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Search Results for " dmh "

Targets Recommended: mTOR

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8569	DMH-25	mTOR	PI3K/Akt/mTOR signaling
	DMH-25 是一种新型共价有效的 mTOR 抑制剂，在体内对三阴性乳腺癌细胞具有抗肿瘤活性。
T1942	DMH-1 DMH1	ALK; Autophagy; TGF-beta/Smad	Angiogenesis; Autophagy; Stem Cells; Tyrosine Kinase/Adaptors
	DMH-1 是一种选择性 BMP 抑制剂，对 ALK1、ALK2、ALK3和 ALK6的 IC50值分别为 27、107.9、<5和 47.6 nM。
T22737	DMH4	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	DMH4 是一种有效的选择性 VEGFR2 抑制剂，其 IC50 为 0.16 µM。
T25346	DMH2 DMH-2,DMH 2
	DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.
T37586	DMHAPC-Chol
	DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells when used at lipid concentrations greater than 20 μM. DMHAPC-Chol, as part of a lipoplex with DOPE , has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to delive...
T40898	DMHCA
	DMHCA, a potent, selective LXR agonist, specifically activates the LXR pathway's cholesterol efflux arm, avoiding triglyceride synthesis stimulation. This compound exhibits anti-inflammatory properties and is utilized in researching cholesterol homeostasis and diabetes.
T83934	DMHBO+
	DMHBO+是一种阳离子荧光团。通过与辣椒适体结合激活其荧光(Kd = 12 nM)，形成的Chili-DMHBO+复合体模仿红色荧光蛋白，适用于细胞中RNA的成像。它是理想的FRET供体，可与罗丹明染料Atto 590配合使用，在基于FRET的RNA分析系统中有应用。激发/发射峰值(λ) = 456/592 nm；量子产率 = 0.1；斯托克斯位移 = 136 nm。

化合物

Target: ALK, Autophagy, TGF-beta/Smad

Synonym: DMH-2,DMH 2

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01257	Dystonin Protein, Human, Recombinant (His) DT,BP230,Dystonin,BP240,DST,DMH,BPAG1,KIAA0728	Human	P. pastoris (Yeast)
	Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo...
TMPH-01256	Dystonin Protein, Human, Recombinant (His & SUMO) DT,DST,BPAG1,BP240,BP230,KIAA0728,Dystonin,DMH	Human	E. coli
	Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo...

重组蛋白

Dystonin Protein, Human, Recombinant (His)

Cat.No: TMPH-01257

Species: Human

Expression System: P. pastoris (Yeast)

Dystonin Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01256

Species: Human

Expression System: E. coli

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