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Cat. No.	Product Name	Target	Signaling Pathways
T1385	Amlodipine 氨氯地平,UK-48340	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Amlodipine (UK-48340) 是可口服的二氢吡啶钙通道阻滞剂，有抗心绞痛作用。它通过阻断电压依赖性的 L 型钙通道，从而抑制钙离子内流，用于高血压和癌症的研究。
T0231	Amlodipine Besylate Amlodipine benzenesulfonate,苯磺酸氨氯地平	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Amlodipine Besylate (Amlodipine benzenesulfonate) 是可口服的二氢吡啶钙通道阻滞剂，有抗心绞痛作用。它通过阻断电压依赖性的 L 型钙通道，从而抑制钙离子内流，用于高血压和癌症的研究。
T15757	Limaprost 17α,20-dimethyl-δ2-PGE1,利马前列素,OP1206,ONO1206	PGE Synthase	Immunology/Inflammation
	Limaprost (17α,20-dimethyl-δ2-PGE1) 是PGE1类似物，也是口服具有活性的血管舒张剂。它能够增加血流量以及减少血小板聚集。它具有抗心绞痛的功能，可用于疼痛的缓解，以及用于研究缺血性症状。
T31577	Droprenilamine Valcor
	Droprenilamine (Valcor) 是戊烯胺的脂环族衍生物，具有抗心绞痛作用。
T68853	Diproteverine HCl	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Diproteverine HCl 是具有抗心绞痛特性的新型钙拮抗剂,具有解痉活性和血管活性。
T0207	Ranolazine dihydrochloride 盐酸雷诺嗪,雷诺嗪二盐酸盐,RS 43285,Ranolazine 2HCl	Calcium Channel; Sodium Channel; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Ranolazine dihydrochloride (Ranolazine 2HCl) 是一种抗心绞痛和抗缺血剂，可通过抑制内向钠电流的后期作用来发挥功效，而不会影响心率或血压。它对 INa 和 IKr 的 IC50值分别为 6 μM 和 12 μM。它还是脂肪酸氧化的部分抑制剂。
T1496	Amiodarone hydrochloride 盐酸胺碘酮,Amiodar,Amiodarone HCl,Nexterone	Potassium Channel; Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Amiodarone hydrochloride (Amiodarone HCl) 是一种抗心绞痛和 III 类抗心律失常药物，通过抑制钾通道和电压门控钠通道来增加心室和心房肌肉作用的持续时间，可导致心率和血管阻力降低。它通过成纤维细胞中的 ERK1/2和 p38 MAPK 信号传导诱导细胞增殖和肌成纤维细胞分化，可研究室上性和室性心律失常。
T27183	Diproteverine
	Diproteverine is a calcium antagonist, it has antianginal property.
T71021	Fendiline
	Fendiline is a coronary vasodilator that inhibits calcium function in muscle cells in excitation-contraction coupling; proposed as an antiarrhythmic and antianginal agent.
T15755	Lidoflazine	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Lidoflazine is a high-affinity blocker of the HERG K+ channel and is an antianginal calcium channel blocker. It carries an obvious risk of QT interval prolongation and ventricular arrhythmia.
T26140	RS 5773 RS-5773,RS5773
	RS 5773 is a benzothiazepine derivative with antianginal effects.
T25691	Levamlodipine gentisate (S)-Amlodipine gentisate,(S)-(-)-Amlodipine gentisate
	Levamlodipine gentisate is a pharmacologically active enantiomer of amlodipine. Amlodipine is the dihydropyridine calcium channel blocker used as an antihypertensive and antianginal drug.
T12402L	Penbutolol HOE 893,l-Penbutolol,Levopenbutol,HOE 893D,Betapressin
	Penbutolol is a nonselective beta-blocker utilized as an antihypertensive and an antianginal.
T36723	Desmethyl Ranolazine
	Desmethyl ranolazine is a metabolite of the antianginal agent ranolazine .1It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A. 1.Wang, Y., Chen, X., Sun, Z., et al.Development and validation of a sensitive LC-MS/MS assay for simultaneous quantitation of ranolazine and its three metabolites in human plasmaJ. Chromatogr. B889-89010-16(2012)
TP1234	Amlodipine aspartic acid impurity Amlodipine aspartate
	Amlodipine aspartic acid is a calcium channel blocker compound that exhibits antihypertensive and antianginal properties. It is important to note that Amlodipine aspartic acid impurity is an impurity specific to this compound.
T27302	Falipamil AQ-A 39,AQ-A-39,AQ-A39
	Falipamil is a verapamil derivative and a calcium channel antagonist. Falipamil exerts antitachycardic effects by a direct action on the sinus node. Falipamil decreases HR at exercise in normal subjects and may exert antianginal effects in patients with m
T29183	YM-430 YM-15430,YM-15430-1,YM-154301,YM-15430-2,YM430,YM-15430-3
	YM-430 is a β1 adrenergic receptor antagonist and a calcium channel antagonist. YM430 could be both an antianginal and antihypertensive agent. YM430 (10(-8)-10(-6) M) inhibited 3,4-diaminopyridine-induced rhythmic contractions with an IC50 value of 59.2 n

化合物

Cat.No: T1385

Synonym: 氨氯地平,UK-48340

Target: Calcium Channel

Amlodipine Besylate

Cat.No: T0231

Synonym: Amlodipine benzenesulfonate,苯磺酸氨氯地平

Target: Calcium Channel

Cat.No: T15757

Synonym: 17α,20-dimethyl-δ2-PGE1,利马前列素,OP1206,ONO1206

Target: PGE Synthase

Cat.No: T31577

Synonym: Valcor

Diproteverine HCl

Cat.No: T68853

Target: Calcium Channel

Ranolazine dihydrochloride

Cat.No: T0207

Synonym: 盐酸雷诺嗪,雷诺嗪二盐酸盐,RS 43285,Ranolazine 2HCl

Target: Calcium Channel, Sodium Channel, Autophagy

Amiodarone hydrochloride

Cat.No: T1496

Synonym: 盐酸胺碘酮,Amiodar,Amiodarone HCl,Nexterone

Target: Potassium Channel, Adrenergic Receptor, Autophagy

Cat.No: T27183

Cat.No: T71021

Cat.No: T15755

Target: Calcium Channel

Cat.No: T26140

Synonym: RS-5773,RS5773

Levamlodipine gentisate

Cat.No: T25691

Synonym: (S)-Amlodipine gentisate,(S)-(-)-Amlodipine gentisate

Cat.No: T12402L

Synonym: HOE 893,l-Penbutolol,Levopenbutol,HOE 893D,Betapressin

Desmethyl Ranolazine

Cat.No: T36723

Amlodipine aspartic acid impurity

Cat.No: TP1234

Synonym: Amlodipine aspartate

Cat.No: T27302

Synonym: AQ-A 39,AQ-A-39,AQ-A39

Cat.No: T29183

Synonym: YM-15430,YM-15430-1,YM-154301,YM-15430-2,YM430,YM-15430-3

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