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Targets Recommended: Apoptosis JAK Bcr-Abl DUB Autophagy

抑制剂 & 化合物

天然产物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6300	Degrasyn WP1130	Apoptosis; JAK; Bcr-Abl; DUB; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors; Ubiquitination
	Degrasyn (WP1130) 是一种可渗透细胞的去泛素化酶(DUB)抑制剂，直接抑制USP9x，USP5，USP14和UCH37的DUB 活性。它减弱抗细胞凋亡蛋白Bcr-Abl 和JAK2。
T20435L	Leuphasyl TFA	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Leuphasyl TFA 是一种酰胺肽，一种 δ-阿片受体激动剂，是一种抗降解的长效 Leu-脑啡肽类似物，用于研究 δ 阿片受体的信号通路。它是一种有效的长效 Leu-脑啡肽类似物，可抵抗酶促降解。
T23709	alphaSYN-IN-NAB2 alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2
	alphaSYN-IN-NAB2 是一种神经元保护剂，是一种由 NAB2基因编码的蛋白质。NAB2 高效且具有选择性地保护多种细胞免受 α-syn 毒性。NAB2 对依赖于 E3 泛素连接酶 Rsp5/Nedd4 的内体转运具有促进作用。NAB2 确定 α-syn 生物学中的一个可活性分子节点，该节点可以纠正其潜在病理学的多个方面，包括功能失调的内体和内质网到高尔基体囊泡的运输。NAB2参与细胞分化、凋亡和应激反应等细胞过程，可用来研究癌症、神经发育和神经元活动。
T16954	Sulfasymazine	Antibacterial	Microbiology/Virology
	Sulfasymazine is a sulfonamide drug.
T31588	Dynasylan 1161 Y 9138
	Dynasylan 1161 是一种双官能有机硅烷，可以与合适的聚合物反应。在水存在时，Dynasylan 1161可与各种无机基材结合。

化合物

Degrasyn

Cat.No: T6300

Synonym: WP1130

Target: Apoptosis, JAK, Bcr-Abl, DUB, Autophagy

Leuphasyl TFA

Cat.No: T20435L

Synonym:

Target: Opioid Receptor

alphaSYN-IN-NAB2

Cat.No: T23709

Synonym: alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2

Target: Antibacterial

Cat. No.	Product Name	Target	Signaling Pathways
T7682	Asymmetric dimethylarginine	Endogenous Metabolite; NO Synthase; NOD	Immunology/Inflammation; Metabolism; NF-κB
	Asymmetric dimethylarginine 是内源性一氧化氮合成酶抑制剂，可以作为内皮功能障碍的标志。
T25596	Lactiflorasyne
	Lactiflorasyne is a bioactive chemical from Artemisia lactiflora Wall that contains an ester group, a spiro system and two triple bonds.
TN3771	Dasycarpol	Others	Others
	Dasycarpol(9beta-Hydroxyfraxinellone) shows significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM. Dasycarpol also shows moderate inhibitory activity on lung
T83601	(+)-Diasyringaresinol
	(+)-Diasyringaresinol 是从 Aquilaria agallocha 提取的一种木质素化合物。

天然产物

Asymmetric dimethylarginine

Cat.No: T7682

Synonym:

Target: Endogenous Metabolite, NO Synthase, NOD

(+)-Diasyringaresinol

Cat.No: T83601

Synonym:

Target:

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02001	RTN4 Protein, Human, Recombinant (GST) UNG1,NOGO,reticulon 4,RTN4-A,Nbla00271,NOGO-A,RTN-X,NSP,UNG1...	Human	E. coli
	Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that contains one reticulon domain. Isoform 1 of RTN4 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 of RTN4 is widely expressed except for the liver. Isoform 3 of RTN4 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 ...
TMPY-00488	COASY Protein, Human, Recombinant (His) pOV-2,CoA synthase,PPAT,DPCK,NBIA6,NBP,UKR1	Human	E. coli
	COASY Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.5 kDa and the accession number is Q13057-1.