转化生长因子-β 家族

转化生长因子-β (Transforming Growth Factor-β, TGF-β) 是一种多功能细胞因子，属于转化生长因子超家族，包括三种不同的哺乳动物亚型（TGF-β 1~3，HGNC编号TGFB1、TGFB2、TGFB3）和许多其他信号蛋白。TGFB 蛋白由所有白细胞谱系产生。活化的 TGF-β 复合物与其他因子形成与 TGF-β 受体结合的丝氨酸/苏氨酸激酶复合物。TGF-β受体由1型和2型受体亚基组成。TGF-β结合后，2型受体激酶磷酸化并激活1型受体激酶，从而激活信号级联反应。TGF-β在干细胞分化以及T细胞调控和分化中也起着至关重要的作用。由于其在免疫和干细胞调控和分化中的作用，它是癌症、自身免疫性疾病和传染病领域中研究最多的细胞因子。

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPJ-01290	Neurturin Protein, Human, Recombinant Neurturin Protein, Human, Recombinant	Human	E. coli
TMPJ-01290	Neurturin is a member of the GDNF family of ligands, which include glial cell-derived neurotrophic factor (GDNF), Neurturin, Persephin, and Artemin. Neurturin is...
TMPJ-01414	GDF-15 Protein, Mouse, Recombinant (His & Flag) GDF-15 Protein, Mouse, Recombinant (His & Flag)	Mouse	HEK293 Cells
TMPJ-01414	Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be ...
TMPK-00109	Artemin Protein, Human, Recombinant (hFc) Artemin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-00109	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor ...
TMPK-00196	GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
TMPK-00196	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, i...
TMPK-00197	GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated	Human	HEK293 Cells
TMPK-00197	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacter...
TMPK-00198	GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
TMPK-00198	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacter...
TMPK-00258	Latent TGF beta 3 Protein, Human, Recombinant (His) Latent TGF beta 3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPK-00258	Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, inc...
TMPK-00259	Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
TMPK-00259	Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, inc...
TMPK-00328	TGFBR2 Protein, Human, Recombinant (mFc & Avi) TGFBR2 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293 Cells
TMPK-00328	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TMPK-00329	TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00329	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TMPK-00569	GDF-15 Protein, Canine, Recombinant (His) GDF-15 Protein, Canine, Recombinant (His)	Canine	E. coli
TMPK-00569	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, i...
TMPK-00663	GDF-15 Protein, Cynomolgus, Recombinant (hFc) GDF-15 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
TMPK-00663	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacter...
TMPK-00664	GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated	Cynomolgus	HEK293 Cells
TMPK-00664	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacter...
TMPK-00665	GDF-15 Protein, Cynomolgus, Recombinant (His) GDF-15 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
TMPK-00665	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacter...
TMPK-01243	GDF-15 Protein, Rat, Recombinant (His) GDF-15 Protein, Rat, Recombinant (His)	Rat	E. coli
TMPK-01243	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, i...
TMPK-01244	GDF-15 Protein, Mouse, Recombinant (hFc) GDF-15 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
TMPK-01244	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacter...
TMPK-01245	GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated	Mouse	HEK293 Cells
TMPK-01245	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacter...
TMPK-01246	GDF-15 Protein, Mouse, Recombinant (His) GDF-15 Protein, Mouse, Recombinant (His)	Mouse	E. coli
TMPK-01246	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacter...
TMPY-00229	Latent TGF beta 1 Protein, Canine, Recombinant (His) Latent TGF beta 1 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
TMPY-00229	Latent TGF beta 1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa.
TMPY-00231	TGF beta 2 Protein, Canine, Recombinant (His) TGF beta 2 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
TMPY-00231	TGF beta 2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession num...