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转化生长因子-β 家族

转化生长因子-β 家族

转化生长因子-β (Transforming Growth Factor-β, TGF-β) 是一种多功能细胞因子,属于转化生长因子超家族,包括三种不同的哺乳动物亚型(TGF-β 1~3,HGNC编号TGFB1、TGFB2、TGFB3)和许多其他信号蛋白。TGFB 蛋白由所有白细胞谱系产生。活化的 TGF-β 复合物与其他因子形成与 TGF-β 受体结合的丝氨酸/苏氨酸激酶复合物。TGF-β受体由1型和2型受体亚基组成。TGF-β结合后,2型受体激酶磷酸化并激活1型受体激酶,从而激活信号级联反应。TGF-β在干细胞分化以及T细胞调控和分化中也起着至关重要的作用。由于其在免疫和干细胞调控和分化中的作用,它是癌症、自身免疫性疾病和传染病领域中研究最多的细胞因子。

TargetMol Recombinant Protein
1 2 3 4
Species
Canine (5)
Cynomolgus (6)
Human (43)
Mouse (26)
Rat (13)
Rhesus (2)
Expression System
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (12)
HEK293 Cells (56)
P. pastoris (Yeast) (1)
Tag
C-6xHis (3)
C-His (14)
C-hFc (1)
C-mFc-Avi (2)
GST (1)
His (1)
N-6xHis (4)
N-6xHis-Avi (1)
N-6xHis-Flag (1)
N-8xHis-Avi (3)
N-8xHis-Flag (1)
N-Avi (3)
N-His (8)
N-His-Avi (1)
N-His-GST (2)
N-hFc (15)
Tag Free (15)
Cat. No. Product Name / Synonyms Species Expression System
TMPY-00413 Latent TGF beta 2 Protein, Mouse, Recombinant (His)
Latent TGF beta 2 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
TGF beta 2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession nu...
TMPY-00990 Lefty-A Protein, Human, Recombinant (hFc)
Lefty-A Protein, Human, Recombinant (hFc)
Human HEK293 Cells
left-right determination factor 2 (Lefty2), also known as Left-right determination factor A (Lefty A), endometrial bleeding associated factor (left-right determi...
TMPY-01190 INHBB Protein, Human, Recombinant (His)
INHBB Protein, Human, Recombinant (His)
Human HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes ar...
TMPY-01576 Artemin Protein, Mouse, Recombinant (hFc)
Artemin Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor ...
TMPY-01817 GDF-10 Protein, Mouse, Recombinant (hFc)
GDF-10 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
BMP-3b / GDF-10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic p...
TMPY-01846 Activin A Protein, Mouse, Recombinant (His)
Activin A Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes ar...
TMPY-02911 GDNF Protein, Rat, Recombinant (His)
GDNF Protein, Rat, Recombinant (His)
Rat Baculovirus Insect Cells
GDNF Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number i...
TMPY-03291 SMAD2 Protein, Mouse, Recombinant (His & GST)
SMAD2 Protein, Mouse, Recombinant (His & GST)
Mouse Baculovirus Insect Cells
SMAD2 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/T...
TMPY-03292 SMAD5 Protein, Mouse, Recombinant (His & GST)
SMAD5 Protein, Mouse, Recombinant (His & GST)
Mouse Baculovirus Insect Cells
SMAD5 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 79.9 kDa and the a...
TMPY-03419 SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST)
SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST)
Human,Mouse,Rat Baculovirus Insect Cells
SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr p...
TMPY-03469 SMAD5 Protein, Mouse, Recombinant
SMAD5 Protein, Mouse, Recombinant
Mouse Baculovirus Insect Cells
SMAD5 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 52.2 kDa and the accession number is P97454.
TMPY-04534 GDF-8 Protein, Mouse, Recombinant (hFc)
GDF-8 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
GDF-8 / Myostatin / MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a po...
TMPY-04535 GDNF Protein, Canine, Recombinant (hFc)
GDNF Protein, Canine, Recombinant (hFc)
Canine HEK293 Cells
GDNF Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is...
TMPY-04577 TGF beta 2 Protein, Rhesus, Recombinant (His)
TGF beta 2 Protein, Rhesus, Recombinant (His)
Rhesus HEK293 Cells
TGF beta 2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession num...
TMPY-05029 INHBE Protein, Human, Recombinant (hFc)
INHBE Protein, Human, Recombinant (hFc)
Human HEK293 Cells
INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Th...
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa...
TMPY-05314 TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
Mouse HEK293 Cells
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and th...
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa...
TMPY-06355 Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)
Human HEK293 Cells
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10...
TMPY-06970 GDNF Protein, Human, Recombinant
GDNF Protein, Human, Recombinant
Human E. coli
GDNF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is P39905-1.
Latent TGF beta 2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00413
Species: Mouse
Expression System: HEK293 Cells
Tag: C-His
Lefty-A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00990
Species: Human
Expression System: HEK293 Cells
Tag: N-hFc
INHBB Protein, Human, Recombinant (His)
Cat.No: TMPY-01190
Species: Human
Expression System: HEK293 Cells
Tag: C-His
Artemin Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01576
Species: Mouse
Expression System: HEK293 Cells
Tag: N-hFc
GDF-10 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01817
Species: Mouse
Expression System: HEK293 Cells
Tag: N-hFc
Activin A Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01846
Species: Mouse
Expression System: HEK293 Cells
Tag: C-His
GDNF Protein, Rat, Recombinant (His)
Cat.No: TMPY-02911
Species: Rat
Expression System: Baculovirus Insect Cells
Tag: N-His
SMAD2 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-03291
Species: Mouse
Expression System: Baculovirus Insect Cells
Tag: His, GST
SMAD5 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-03292
Species: Mouse
Expression System: Baculovirus Insect Cells
Tag: N-His-GST
SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST)
Cat.No: TMPY-03419
Species: Human,Mouse,Rat
Expression System: Baculovirus Insect Cells
Tag: N-His-GST
SMAD5 Protein, Mouse, Recombinant
Cat.No: TMPY-03469
Species: Mouse
Expression System: Baculovirus Insect Cells
Tag: Tag Free
GDF-8 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04534
Species: Mouse
Expression System: HEK293 Cells
Tag: N-hFc
GDNF Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-04535
Species: Canine
Expression System: HEK293 Cells
Tag: N-hFc
TGF beta 2 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-04577
Species: Rhesus
Expression System: HEK293 Cells
Tag: C-His
INHBE Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05029
Species: Human
Expression System: HEK293 Cells
Tag: N-hFc
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05313
Species: Mouse
Expression System: HEK293 Cells
Tag: C-His
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05314
Species: Mouse
Expression System: HEK293 Cells
Tag: C-His
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05521
Species: Human
Expression System: HEK293 Cells
Tag: C-His
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)
Cat.No: TMPY-06355
Species: Human
Expression System: HEK293 Cells
Tag: C-His
GDNF Protein, Human, Recombinant
Cat.No: TMPY-06970
Species: Human
Expression System: E. coli
Tag: Tag Free
1 2 3 4
TargetMol Loading
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