转化生长因子-β 家族

转化生长因子-β (Transforming Growth Factor-β, TGF-β) 是一种多功能细胞因子，属于转化生长因子超家族，包括三种不同的哺乳动物亚型（TGF-β 1~3，HGNC编号TGFB1、TGFB2、TGFB3）和许多其他信号蛋白。TGFB 蛋白由所有白细胞谱系产生。活化的 TGF-β 复合物与其他因子形成与 TGF-β 受体结合的丝氨酸/苏氨酸激酶复合物。TGF-β受体由1型和2型受体亚基组成。TGF-β结合后，2型受体激酶磷酸化并激活1型受体激酶，从而激活信号级联反应。TGF-β在干细胞分化以及T细胞调控和分化中也起着至关重要的作用。由于其在免疫和干细胞调控和分化中的作用，它是癌症、自身免疫性疾病和传染病领域中研究最多的细胞因子。

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPY-03945	Latent TGF beta 1 Protein, Rat, Recombinant (His) Latent TGF beta 1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
TMPY-03945	Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accessi...
TMPY-00608	TGF beta 1 Protein, Rat/Mouse, Recombinant TGF beta 1 Protein, Rat/Mouse, Recombinant	Mouse,Rat	HEK293 Cells
TMPY-00608	TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.
TMPY-04211	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPY-04211	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa.
TMPY-02638	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant	Human,Rhesus,Cynomolgus,Canine	CHO Cells
TMPY-02638	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession...
TMPY-00500	Latent TGF beta 1 Protein, Mouse, Recombinant (His) Latent TGF beta 1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPY-00500	Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the acces...
TMPY-04727	GDF-15 Protein, Human, Recombinant (His) GDF-15 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
TMPY-04727	GDF-15 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 13.7 kDa and the accession number is Q99988.
TMPY-01073	GDF-15 Protein, Human, Recombinant (hFc) GDF-15 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-01073	GDF-15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.6 kDa and the accession number...
TMPY-06247	TGF beta 3 Protein, Human, Recombinant (hFc) TGF beta 3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-06247	TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession nu...
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293 Cells
TMPJ-00249	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and ...
TMPJ-00254	TGF beta 3 Protein, Human/Mouse/Rat, Recombinant TGF beta 3 Protein, Human/Mouse/Rat, Recombinant	Human,Mouse,Rat	HEK293 Cells
TMPJ-00254	Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted a...
TMPJ-00258	TGF beta 2 Protein, Human, Recombinant TGF beta 2 Protein, Human, Recombinant	Human	HEK293 Cells
TMPJ-00258	Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular fun...
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant TGF beta 2 Protein, Mouse/Rat, Recombinant	Mouse,Rat	HEK293 Cells
TMPJ-00261	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deleti...
TMPJ-01471	Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant	Human/Mouse/Rat	HEK293 Cells
TMPJ-01471	Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfami...
TMPY-01133	Latent TGF beta 1 Protein, Human, Recombinant (His) Latent TGF beta 1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPY-01133	Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the acces...
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293) GDNF Protein, Human, Recombinant (HEK293)	Human	HEK293 Cells
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2...