抑制性免疫检查点蛋白

抑制性免疫检查点分子在维持免疫稳态中起着至关重要的作用：它们效应 T 细胞上的表达确保了效应 T 细胞反应的适当紧缩；它们在调节性 T (Treg) 细胞上的表达促进了Treg细胞的抑制功能。阻断共抑制分子已被证实可以增强宿主对各种癌症的免疫应答，在癌症治疗中表现出显著的临床效果。

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Expression System：

Tag：

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPJ-00212	CD47 Protein, Human, Recombinant (mFc) CD47 Protein, Human, Recombinant (mFc)	Human	Human Cells
TMPJ-00212	CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 b...
TMPJ-00218	SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
TMPJ-00218	SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a ...
TMPJ-00233	CD200R1/CRTR2 Protein, Human, Recombinant (His) CD200R1/CRTR2 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00233	Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and...
TMPJ-00321	LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
TMPJ-00321	Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene co...
TMPJ-00353	ILDR2 Protein, Human, Recombinant (His) ILDR2 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00353	ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasi...
TMPJ-00420	CTLA-4 Protein, Mouse, Recombinant (Flag) CTLA-4 Protein, Mouse, Recombinant (Flag)	Mouse	Human Cells
TMPJ-00420	Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity w...
TMPJ-00427	LAIR1 Protein, Rhesus macaque, Recombinant (His) LAIR1 Protein, Rhesus macaque, Recombinant (His)	Rhesus Macaque	Human Cells
TMPJ-00427	Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear c...
TMPJ-00428	PVRIG Protein, Mouse, Recombinant (hFc) PVRIG Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
TMPJ-00428	PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembr...
TMPJ-00433	VSIR Protein, Cynomolgus, Recombinant (His) VSIR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-00433	platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediat...
TMPJ-00435	PVRIG Protein, Cynomolgus, Recombinant (hFc) PVRIG Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-00435	PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembr...
TMPJ-00436	PVRIG Protein, Cynomolgus, Recombinant (His) PVRIG Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-00436	PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembr...
TMPJ-00550	Siglec-9 Protein, Human, Recombinant (hFc) Siglec-9 Protein, Human, Recombinant (hFc)	Human	Human Cells
TMPJ-00550	Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, f...
TMPJ-00551	Siglec-9 Protein,Human, Recombinant(aa 18-348, His) Siglec-9 Protein,Human, Recombinant(aa 18-348, His)	Human	Human Cells
TMPJ-00551	Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, f...
TMPJ-00555	B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	Human Cells
TMPJ-00555	The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C...
TMPJ-00556	B7-2 Protein, Human, Recombinant (His) B7-2 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00556	The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C...
TMPJ-00599	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His) TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
TMPJ-00599	Hepatitis A virus cellular receptor 2（HAVCR2）is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein ...
TMPJ-00613	CD47 Protein, Rhesus macaque, Recombinant (hFc) CD47 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus macaque	Human Cells
TMPJ-00613	CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 b...
TMPJ-00614	CD47 Protein, Rhesus macaque, Recombinant (His & Flag) CD47 Protein, Rhesus macaque, Recombinant (His & Flag)	Rhesus Macaque	Human Cells
TMPJ-00614	CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral mem...
TMPJ-00624	TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His) TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)	Marmoset	Human Cells
TMPJ-00624	T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of...
TMPJ-00626	CD160 Protein, Rhesus macaque, Recombinant (hFc) CD160 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus macaque	Human Cells
TMPJ-00626	CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in wh...