抑制性免疫检查点蛋白

抑制性免疫检查点分子在维持免疫稳态中起着至关重要的作用：它们效应 T 细胞上的表达确保了效应 T 细胞反应的适当紧缩；它们在调节性 T (Treg) 细胞上的表达促进了Treg细胞的抑制功能。阻断共抑制分子已被证实可以增强宿主对各种癌症的免疫应答，在癌症治疗中表现出显著的临床效果。

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Cat. No.	Product Name / Synonyms	Species	Expression System
TMPJ-00627	CD160 Protein, Rhesus macaque, Recombinant (His) CD160 Protein, Rhesus macaque, Recombinant (His)	Rhesus macaque	Human Cells
TMPJ-00627	CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in wh...
TMPJ-00629	TIGIT Protein, Cynomolgus, Recombinant (His) TIGIT Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-00629	T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT ...
TMPJ-00630	B7-1 Protein, Cynomolgus, Recombinant (hFc) B7-1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-00630	Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-pr...
TMPJ-00632	B7-2 Protein, Cynomolgus, Recombinant (hFc) B7-2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-00632	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-00635	CTLA-4 Protein, Cynomolgus, Recombinant (hFc) CTLA-4 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-00635	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with...
TMPJ-00636	CTLA-4 Protein, Cynomolgus, Recombinant (His) CTLA-4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-00636	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with...
TMPJ-00637	PD-L1 Protein, Cynomolgus, Recombinant (hFc) PD-L1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-00637	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin ...
TMPJ-00638	PD-L1 Protein, Cynomolgus, Recombinant (His) PD-L1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-00638	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin ...
TMPJ-00640	CTLA-4 Protein, Cavia porcellus, Recombinant (His) CTLA-4 Protein, Cavia porcellus, Recombinant (His)	Cavia porcellus	P. pastoris
TMPJ-00640	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with...
TMPJ-00641	B7-2 Protein, Rhesus macaque, Recombinant (His) B7-2 Protein, Rhesus macaque, Recombinant (His)	Rhesus macaque	Human Cells
TMPJ-00641	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-00659	Galectin-9 Protein, Mouse, Recombinant (GST) Galectin-9 Protein, Mouse, Recombinant (GST)	Mouse	E. coli
TMPJ-00659	Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galect...
TMPJ-00698	BTNL2 Protein, Mouse, Recombinant (His) BTNL2 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
TMPJ-00698	Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I tran...
TMPJ-00949	CD96 Protein, Human, Recombinant (hFc) CD96 Protein, Human, Recombinant (hFc)	Human	Human Cells
TMPJ-00949	The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified...
TMPJ-00950	CD96 Protein, Human, Recombinant (mFc) CD96 Protein, Human, Recombinant (mFc)	Human	Human Cells
TMPJ-00950	The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified...
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His) B7-1 Protein, Rabbit, Recombinant (His)	Rabbit	Human Cells
TMPJ-00958	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of ...
TMPJ-00959	B7-2 Protein, Rabbit, Recombinant (His) B7-2 Protein, Rabbit, Recombinant (His)	Rabbit	Human Cells
TMPJ-00959	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-01086	CD244 Protein, Mouse, Recombinant (His) CD244 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
TMPJ-01086	Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins ha...
TMPJ-01199	BTN2A1 Protein, Human, Recombinant (His) BTN2A1 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-01199	Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein. Mature human Butyrophilin 2A1 consisi...
TMPJ-01242	CD160 Protein, Mouse, Recombinant (His) CD160 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
TMPJ-01242	CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in wh...
TMPJ-01246	BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	Human Cells
TMPJ-01246	Butyrophilin 2A2 (BTN2A2) is a widely expressed type I transmembrane glycoprotein that functions as a negative regulator of immune responses. Mature human Butyro...