抑制性免疫检查点蛋白

抑制性免疫检查点分子在维持免疫稳态中起着至关重要的作用：它们效应 T 细胞上的表达确保了效应 T 细胞反应的适当紧缩；它们在调节性 T (Treg) 细胞上的表达促进了Treg细胞的抑制功能。阻断共抑制分子已被证实可以增强宿主对各种癌症的免疫应答，在癌症治疗中表现出显著的临床效果。

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Expression System：

Tag：

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPK-00260	CD155/PVR Protein, Human, Recombinant (His & Avi) CD155/PVR Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00260	CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tum...
TMPK-00286	Siglec-9 Protein, Human, Recombinant (His & Avi) Siglec-9 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00286	Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells. Aberrant glycosylation occurs in essentially all types of cancers and results ...
TMPK-00287	Siglec-9 Protein, Human, Recombinant (His & Avi), Biotinylated Siglec-9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00287	Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells. Aberrant glycosylation occurs in essentially all types of cancers and results ...
TMPK-00310	BTN3A1 Protein, Human, Recombinant (His & Avi), Biotinylated BTN3A1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00310	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the...
TMPK-00312	Nectin-1 Protein, Human, Recombinant (His & Avi) Nectin-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00312	Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homo...
TMPK-00313	Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00313	Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homo...
TMPK-00314	B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00314	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet ...
TMPK-00315	B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00315	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet ...
TMPK-00470	PVRIG Protein, Mouse, Recombinant (hFc & Avi) PVRIG Protein, Mouse, Recombinant (hFc & Avi)	Mouse	HEK293
TMPK-00470	Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG...
TMPK-00471	PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated	Mouse	HEK293
TMPK-00471	Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG...
TMPK-00476	CD200 Protein, Cynomolgus, Recombinant (His) CD200 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00476	CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with...
TMPK-00530	BTLA Protein, Cynomolgus, Recombinant (His) BTLA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00530	B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibi...
TMPK-00535	FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag) FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag)	Cynomolgus	HEK293
TMPK-00535	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immun...
TMPK-00536	FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated	Cynomolgus	HEK293
TMPK-00536	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immun...
TMPK-00556	BTN3A1 Protein, Cynomolgus, Recombinant (His & Avi) BTN3A1 Protein, Cynomolgus, Recombinant (His & Avi)	Cynomolgus	HEK293
TMPK-00556	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the...
TMPK-00557	BTN3A1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated BTN3A1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated	Cynomolgus	HEK293
TMPK-00557	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the...
TMPK-00559	CD300A Protein, Cynomolgus, Recombinant (Avi) CD300A Protein, Cynomolgus, Recombinant (Avi)	Cynomolgus	HEK293
TMPK-00559	CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential...
TMPK-00560	CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated	Cynomolgus	HEK293
TMPK-00560	CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential...
TMPK-00561	CD300A Protein, Cynomolgus, Recombinant (His) CD300A Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00561	CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential...
TMPK-00584	BTN2A2 Protein, Mouse, Recombinant (His) BTN2A2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPK-00584	Butyrophilin (BTN) genes encode a set of related proteins. Cell surface BTN2A2 protein, such as the B7 family molecule programmed death ligand 1, was upregulated...