抑制性免疫检查点蛋白

抑制性免疫检查点分子在维持免疫稳态中起着至关重要的作用：它们效应 T 细胞上的表达确保了效应 T 细胞反应的适当紧缩；它们在调节性 T (Treg) 细胞上的表达促进了Treg细胞的抑制功能。阻断共抑制分子已被证实可以增强宿主对各种癌症的免疫应答，在癌症治疗中表现出显著的临床效果。

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Expression System：

Tag：

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPJ-01247	BTN2A2 Protein, Human, Recombinant (hFc) BTN2A2 Protein, Human, Recombinant (hFc)	Human	Human Cells
TMPJ-01247	Butyrophilin 2A2 (BTN2A2) is a widely expressed type I transmembrane glycoprotein that functions as a negative regulator of immune responses. Mature human Butyro...
TMPJ-01421	LAG-3 Protein, Cynomolgus, Recombinant (hFc) LAG-3 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-01421	Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene co...
TMPJ-01455	Galectin-9 Protein, Human, Recombinant (His) Galectin-9 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-01455	Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galect...
TMPK-00062	CD160 Protein, Human, Recombinant (His & Avi) CD160 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00062	CD160 (also Natural killer cell receptor BY55) is a 27 ‑ 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic c...
TMPK-00112	CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00112	CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune ...
TMPK-00166	PD-L2 Protein, Human, Recombinant (His & Avi) PD-L2 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00166	PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T...
TMPK-00172	B7-H4 Protein, Human, Recombinant (His & Avi) B7-H4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00172	B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas i...
TMPK-00177	LAIR1 Protein, Human, Recombinant (His & Avi) LAIR1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00177	LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig sup...
TMPK-00178	B7-1 Protein, Human, Recombinant (His & Avi) B7-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00178	Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal ne...
TMPK-00179	B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated	Human	HEK293
TMPK-00179	Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal ne...
TMPK-00180	PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated	Human	HEK293
TMPK-00180	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp...
TMPK-00181	PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated	Mouse	HEK293
TMPK-00181	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp...
TMPK-00182	PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated	Human	HEK293
TMPK-00182	B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been ident...
TMPK-00186	CD300A Protein, Human, Recombinant (Avi) CD300A Protein, Human, Recombinant (Avi)	Human	HEK293
TMPK-00186	CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential...
TMPK-00187	CD300A Protein, Human, Recombinant (Avi), Biotinylated CD300A Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293
TMPK-00187	CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential...
TMPK-00189	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His & Avi), Biotinylated TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00189	Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded...
TMPK-00190	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His) TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His)	Human	HEK293
TMPK-00190	Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded...
TMPK-00204	FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated	Human	HEK293
TMPK-00204	Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1...
TMPK-00212	CD300A Protein, Mouse, Recombinant (His) CD300A Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPK-00212	CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential...
TMPK-00222	SLAMF6 Protein, Human, Recombinant (His & Avi) SLAMF6 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00222	SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobul...