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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T25538	Iperoxo Iperoxo iodide	AChR	Neuroscience
	Iperoxo (Iperoxo iodide) 是毒蕈碱 AChR 的激动剂，可用于探测毒蕈碱受体的激活相关构象转变。
T30601	BTC
	BTC is a human G-quadruplexes regulator, inducing dynamic transitions between the ensembles of unfolded conformations to the folded state in G-quadruplexes, altering the rod shaped DNA sequences into globular quadruplexes with a decrease in hydrodynamic r
T62623	G247
	G247是一种特异的 MsbA 抑制剂。G247 作为跨膜结构域 (TMDs) 楔形物，对称地增加核苷酸结合结构域 (NBDs) 的分离，并防止 MsbA 的构象转变。G247 利用增加 NBDs 间的距离来抑制 ATP 酶活性。
T61852	hCAIX-IN-8
	hCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX, demonstrating potent inhibitory activity against CAIX with an IC50 value of 0.024 μM. It also exhibits inhibitory activity against CAII and CAVA with IC50 values of 1.99 μM and 1.10 μM, respectively. Furthermore, hCAIX-IN-8 exhibits anti-proliferative effects and low toxicity. It effectively reduces the occurrence of epithelial-to-mesenchymal transitions and promotes apoptosis. Additionally, hCAIX-IN-8 effectively inhi...
T82147	Hydroxy naphthol blue disodium
	Hydroxy naphthol blue disodium 作为一种钙离子金属指示剂和碱土金属离子比色试剂(λmax = 650 nm)，在pH值介于12至13的环境中表现出明显的颜色变化；该指示剂在钙离子存在时显淡红色，在EDTA二钠作用下则转为深蓝色。
T75348	Malachite Green Carbinol base
	Malachite Green Carbinol base (MGOH, MGCB) 是孔雀石绿(MG)的衍生物，无荧光。Malachite Green Carbinol base (MGOH, MGCB) 可作为 pH 调节剂，MGCB 分子在紫外光照射下释放 OH-，使 pH 值逐渐变化。MGCB 溶液在高压 UV 灯(500w, 50w /cm)照射下迅速由无色变为深绿色。

化合物

Iperoxo

Cat.No: T25538

Synonym: Iperoxo iodide

Hydroxy naphthol blue disodium

Cat.No: T82147

Synonym:

Target:

Malachite Green Carbinol base

Cat.No: T75348

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
TN3910	Ecdysone	Apoptosis; ATPase; Glucocorticoid Receptor; Potassium Channel; Sodium Channel; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism
	Ecdysone 是存在于昆虫和草药中的主要类固醇激素，可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。
T2732	(-)-Epicatechin gallate 表儿茶素没食子酸酯,(−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG	Virus Protease; COX; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) 抑制环加氧酶-1 的IC50值为 7.5 μM。