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Search Results for " tetrahydrochloride "

13

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T35593	Semapimod tetrahydrochloride CPSI-2364 tetrahydrochloride	TLR; MAPK	Immunology/Inflammation; MAPK
	Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) 是一种合成鸟腙丝裂原活化蛋白激酶阻滞剂,也是促炎细胞因子生成抑制剂，干扰巨噬细胞和小胶质细胞功能。Semapimod tetrahydrochloride 可抑制 TLR4 信号传导，抑制 TNF-α、IL-1β 和 IL-6，可用于研究克罗恩病和其他炎症。
T11281L	FGI-106 tetrahydrochloride	Virus Protease; HCV Protease; Influenza Virus; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	FGI-106 tetrahydrochloride 对多种病毒具有抑制活性，有抗埃博拉病毒，裂谷病毒和登革热病毒的 EC50分别为 100 nM，800 nM 和 400-900 nM，抑制非失血性发热病毒HCV 和HIV-1的EC50分别为 200 nM 和 150 nM 。
T10313	AMXT-1501 tetrahydrochloride	Others	Others
	AMXT-1501 tetrahydrochloride is an inhibitor of polyamine transport. It blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells.
T9640	Diethylnorspermine HCl Diethylnorspermine tetrahydrochloride,N1,N11-Diethylnorspermine tetrahydrochloride,DENSPM tetrahydrochloride	Others	Others
	Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) 可有效诱导 SSAT (亚精胺/精胺N1-乙酰转移酶) mRNA，并有效稳定 SSAT 酶活性。
T38608	Brilacidin tetrahydrochloride PMX 30063 tetrahydrochloride
	Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is a defensin mimetic antibiotic compound, exhibiting potent anti-infective antimicrobial activity against a range of bacteria. It demonstrates MIC90 values of 1 μg/mL and 8 μg/mL against the Gram-positive bacteria Streptococcus pneumoniae and Streptococcus viridans, respectively. Additionally, it has a MIC90 value of 8 μg/mL for the Gram-negative bacteria Haemophilus influenzae and a MIC90 value of 4 μg/mL for Pseudomonas aeruginosa.
T78046	RG7800 tetrahydrochloride RO6885247 tetrahydrochloride	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	RG7800 hydrochloride为一可口服SMN2剪接调节剂，其对SMN2剪接及SMN蛋白的EC1.5x值分别为23 nM及87 nM。
T82620	DAB tetrahydrochloride dihydrate 3,3-Diaminobenzidine tetrahydrochloride dihydrate
	3,3-Diaminobenzidine tetrahydrochloride dehydrate 作为染料，在组织化学（HC）及免疫组织化学（IHC）中应用广泛。该化合物主要用于过氧化物酶体染色和线粒体细胞色素c氧化酶活性的检测。
T19013	Hoechst 34580 tetrahydrochloride Hoechst 34580 tetrahydrochloride (23555-00-2 free base),HOE 34580 tetrahydrochloride	Beta Amyloid	Neuroscience
	Hoechst 34580 tetrahydrochloride, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.
T38443	Methoctramine tetrahydrochloride
	Methoctramine tetrahydrochloride is a potent and cardioselective antagonist of the M2 muscarinic receptor, capable of inhibiting Muscarine-induced bradycardia in vivo.
T36182	Neamine tetrahydrochloride
	Neamine tetrahydrochloride 是一种广谱氨基糖苷类抗生素，一种新霉素的降解产物。Neamine tetrahydrochloride 可通过靶向血管生成素 (angiogenin) 发挥抗血管生成作用。Neamine tetrahydrochloride 具有抗菌，抗肿瘤和神经保护活性。
T63897	LDN193189 Tetrahydrochloride
	LDN193189 Tetrahydrochloride 是 BMPI 型受体的选择性抑制剂，能够抑制 ALK2 (IC50: 5 nM) 和 ALK3 (IC50: 30 nM)，对 ALK4，ALK5 和 ALK7 的作用效果弱 (IC50≥500 nM)。
T33267	Me6TREN 4HCl Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl
	Me6TREN 4HCl is a potent and efficacious mobilizing agent of hematopoietic stem and progenitor cells (HSPCs) that can act by activating MMP-9 expression and disrupting the SDF-1α/CXCR4 axis, exhibiting more significant mobilizing effects than G-CSF or AMD
T69841	GC813 sodium
	GC813 is a potent and permeable inhibitor of MERS coronavirus 3CL protease. GC813 is analogue of GC376.

化合物

Semapimod tetrahydrochloride

Cat.No: T35593

Synonym: CPSI-2364 tetrahydrochloride

Target: TLR, MAPK

FGI-106 tetrahydrochloride

Cat.No: T11281L

Target: Virus Protease, HCV Protease, Influenza Virus, HIV Protease

AMXT-1501 tetrahydrochloride

Cat.No: T10313

Target: Others

Diethylnorspermine HCl

Cat.No: T9640

Synonym: Diethylnorspermine tetrahydrochloride,N1,N11-Diethylnorspermine tetrahydrochloride,DENSPM tetrahydrochloride

Target: Others

Brilacidin tetrahydrochloride

Cat.No: T38608

Synonym: PMX 30063 tetrahydrochloride

RG7800 tetrahydrochloride

Cat.No: T78046

Synonym: RO6885247 tetrahydrochloride

Target: DNA/RNA Synthesis

DAB tetrahydrochloride dihydrate

Cat.No: T82620

Synonym: 3,3-Diaminobenzidine tetrahydrochloride dihydrate

Hoechst 34580 tetrahydrochloride

Cat.No: T19013

Synonym: Hoechst 34580 tetrahydrochloride (23555-00-2 free base),HOE 34580 tetrahydrochloride

Target: Beta Amyloid

Methoctramine tetrahydrochloride

Cat.No: T38443

Neamine tetrahydrochloride

Cat.No: T36182

LDN193189 Tetrahydrochloride

Cat.No: T63897

Cat.No: T33267

Synonym: Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl

Cat.No: T69841

Cat. No.	Product Name	Target	Signaling Pathways
T3093	Spermine tetrahydrochloride 精胺盐酸盐,Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Spermine tetrahydrochloride (Musculamine tetrahydrochloride) 是内源性代谢产物的一种。
T38555	Chitotetraose tetrahydrochloride
	Chitotetraose tetrahydrochloride is a short-chain chitin oligomer derived from arbuscular mycorrhizal (AM) fungi. This compound effectively activates the conserved symbiosis signaling pathway (CSSP) in actinorhizal plant species.

天然产物

Spermine tetrahydrochloride

Cat.No: T3093

Synonym: 精胺盐酸盐,Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride

Target: Others, Endogenous Metabolite

Chitotetraose tetrahydrochloride

Cat.No: T38555

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