Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1563 |
Gap19
|
Gap Junction Protein | Cytoskeletal Signaling |
Gap19 是一种衍生自 Cx43 细胞质环九个氨基酸的肽,是选择性连接蛋白 43 半通道阻滞剂。它可以防止 C 末端与 CL 的分子内相互作用,具有保护心肌作用。 | |||
T1960 |
YL-109
|
AhR; Aryl Hydrocarbon Receptor | Immunology/Inflammation; Metabolism |
YL-109是一种抗肿瘤剂,可以通过芳烃受体 AhR 信号传导诱导 Hsp70 相互作用蛋白 (CHIP) 表达,具有抑制乳腺癌细胞生长和侵袭性的能力。 | |||
T7601L |
Carbetocin acetate
醋酸卡贝缩宫素,Carbetocin acetate(37025-55-1 free base),卡贝缩宫素醋酸盐 |
Oxytocin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Carbetocin acetate 是催产素类似物,是催产素受体激动剂,Ki 是 7.1 nM。它对催产素受体的嵌合 N 末端具有高亲和力,Ki 为 1.17 μM。它能透过血脑屏障,可以通过激活 CNS 中的催产素受体而具有类抗抑郁活性,具有用于产后出血的研究潜力。 | |||
T7601 |
Carbetocin
卡贝缩宫素,醋酸卡贝缩宫素 |
Oxytocin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Carbetocin 是催产素类似物,是催产素受体激动剂,Ki 是 7.1 nM。它对催产素受体的嵌合 N 末端具有高亲和力,Ki 为 1.17 μM。它能透过血脑屏障,可以通过激活 CNS 中的催产素受体而具有类抗抑郁活性,具有用于产后出血的研究潜力。 | |||
TP1432 |
Enfuvirtide acetate
醋酸恩夫韦地 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Enfuvirtide acetate 是一种抗HIV-1融合的抑制肽,是一种由 36 个氨基酸组成的线性合成肽。 它具有乙酰化的 N 端和羧酰胺 C 端。 | |||
TP1246L |
ACTH (22-39) acetate
ACTH (22-39) acetate (37548-29-1 Free base) |
Others | Others |
ACTH (22-39) acetate 是促肾上腺皮质激素 (ACTH) 的片段,在 N 末端的第 3 位和第 15 位含有两个脯氨酸残基。 | |||
T7497L |
C3a 70-77 2TFA(63555-63-5(free base))
Complement 3a (70-77) |
Complement System | Immunology/Inflammation |
C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) 是对应于 C3a 的 COOH 末端的八肽。 | |||
T7497L1 |
C3a 70-77 acetate
C3a 70-77 acetate (63555-63-5 Free base) |
Others | Others |
C3a 70-77 acetate 是对应于 C3a 的 COOH 末端的八肽乙酸酯,具有 C3a 的特异性和 1% 至 2% 的生物活性。 | |||
T10389 |
Aspartyl-alanyl-diketopiperazine
DA-DKP |
Interleukin | Immunology/Inflammation |
Aspartyl-alanyl-diketopiperazine (DA-DKP) 是一种由人血白蛋白的 N 端裂解和环化产生的免疫调节分子,通过与 T 淋巴细胞无反应相关的分子途径调节炎症免疫反应。 | |||
T37088L |
pep2m aceate
|
Others | Others |
pep2m aceate 是 GluR2 亚基 C 端与 N-乙基马来酰亚胺敏感融合蛋白相互作用的肽抑制剂。 | |||
T37891L |
GLP-1(32-36)amide acetate
GLP-1(32-36)amide 醋酸盐,GLP-1(32-36)amide acetate(1417302-71-6 Free base) |
Others | Others |
GLP-1(32-36)amide acetate 是一种五肽,衍生自糖调节激素 GLP-1 的 C 末端。GLP-1(32-36)amide acetate 可抑制糖尿病小鼠的体重增加并调节全身葡萄糖代谢。 | |||
TP1865L |
Rhodopsin Epitope Tag acetate
|
Others | Others |
Rhodopsin Epitope Tag acetate 是一种 9 个氨基酸的肽,代表牛视紫红质的 C 末端,广泛用作表位标签。许多抗视紫红质抗体可以识别该表位。 | |||
T17171 |
Trofinetide
NNZ-2566 |
Others | Others |
Trofinetide (NNZ-2566) 是一种内源性 N 末端三肽甘氨酸-脯氨酸-谷氨酸 (GPE) 的合成类似物,在脑损伤的动物模型中显示出神经保护作用。 | |||
T9002 |
squarunkinA
|
Others; Src | Angiogenesis; Others; Tyrosine Kinase/Adaptors |
squarunkinA 是一种新型的 UNC119-货物相互作用调节剂,有效和选择性地抑制代表 Src 激酶 N 端的肉豆蔻酰化肽与 UNC119A 的结合。 | |||
TP1617L |
Chemerin-9 (149-157) acetate
Chemerin-9 (149-157) acetate (676367-27-4 free base) |
Others | Others |
Chemerin-9 (149-157) acetate (676367-27-4 free base) 对应于加工的 chemerin 的 C 末端,保留了全尺寸蛋白质的大部分活性和关于对 chemerinR 的激动。它是 ChemR23 (chemerinR) 的天然配体。 | |||
TP1033L |
Transdermal Peptide Disulfide Acetate
TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base) |
ATPase | Membrane transporter/Ion channel |
Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) 是一种 11 个氨基酸的肽,与 Na+/K+-ATPase β 亚基 (ATP1B1) 结合,主要与 ATP1B1 的 C 端相互作用。透皮肽可以增强许多大分子的透皮传递。透皮肽 TD 1 酰胺是一种新型肽,旨在增强透皮药物传递。 | |||
TP1945L1 |
Pep2m, myristoylated acetate
Pep2m, myristoylated acetate(1423381-07-0 free base) |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Pep2m, myristoylated acetate(1423381-07-0 free base) 是一种细胞可渗透的肉豆蔻酰化形式的 pep2m。 GluA2(AMPA 受体)亚基的 C 末端与 N-乙基马来酰亚胺敏感融合蛋白 (NSF)(一种调节 AMPA 受体功能的蛋白质)之间相互作用的肽抑制剂。降低 CA1 神经元中的突触后电流、培养的海马神经元中 AMPA 介导的电流和 AMPA 受体表面表达。 | |||
TP1616L |
Hsp70-derived octapeptide acetate
Hsp70-derived octapeptide acetate(736171-62-3 free base) |
Others | Others |
Hsp70-derived octapeptide acetate (Hsp70-derived octapeptide acetate)(736171-62-3 free base) 是一组含有四肽重复 (TPR) 的蛋白质,已显示与 70 kDa 热休克同源蛋白 (hsc70) 的 C 末端结构域相互作用。在本研究中,含 TPR 的蛋白质,包括 hsc70 相互作用蛋白 (CHIP)、TPR1 和人富含谷氨酰胺的 TPR 含蛋白 (hSGT) 的 C 端,对 DnaJ 和 hsc70 对荧光素酶重折叠的影响进行了调查。 | |||
T33374 | Mgaipaa | ||
Mgaipaa can be used to elucidate the role of the amino terminus in the activity. | |||
TP1068 |
Pam3CSK4
Pam3Cys-Ser-(Lys)4 |
||
Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs. | |||
TP1849 |
Transportan
|
||
Transportan is a 27 amino acid-long peptide containing 12 functional amino acids from the amino terminus of the neuropeptide galanin and mastoparan in the carboxyl terminus, connected via a lysine. | |||
T41061 |
Histone H3 (116-136), C116-136
Histone H3 (116-136), C116-136 |
||
Histone H3 (116-136), C116-136 is a peptide consisting of amino acids 116 to 136, which spans the C-terminus of histone H3. | |||
TP1855 |
Moth Cytochrome C (MCC) (88-103)
Moth Cytochrome C (MCC) 88-103 |
||
Moth Cytochrome C (MCC) (88-103), derived from the carboxyl terminus of moth cytochrome c, induces positive selection of TCR transgenic thymocytes.This peptide is derived from the carboxyl terminus of moth cytochrome c. Thymic positive and negative select | |||
T7497 |
C3a (70-77)
Complement 3a (70-77),C3a 70-77 |
Complement System | Immunology/Inflammation |
C3a (70-77) 是对应于 C3a 的 COOH 末端的八肽。 | |||
T36623 |
Antileukinate
|
||
Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 μM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury. | |||
TP1162 |
Fibrinopeptide B, human TFA (36204-23-6 free base)
FPB,human TFA,Fibrinopeptide B, human TFA |
||
FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment. | |||
TP2197 |
Pep1-TGL
|
Others | Others |
Peptide containing the 'TGL' motif that corresponds to the C-terminus of GluR1 subunit | |||
T37891 |
GLP-1(32-36)amide
|
||
GLP-1(32-36)amide is a pentapeptide compound derived from the C terminus of the glucoregulatory hormone GLP-1. This compound has shown potential in inhibiting weight gain and regulating glucose metabolism in diabetic mice[1][2]. | |||
TP1641 |
[pSer2, pSer5, pSer7]-CTD TFA
|
||
[pSer2, pSer5, pSer7]-CTD (TFA) is a substrate for CDK7(cyclin-dependent protein kinase), a phosphorylated polypeptide at ser2, ser5, and ser7 of RNA polymerase II carboxyl terminus (CTD). | |||
TP1683 |
[pSer2, pSer5, pSer7]-CTD
|
||
[pSer2, pSer5, pSer7]-CTD is a substrate for CDK7(cyclin-dependent protein kinase), a phosphorylated polypeptide at ser2, ser5, and ser7 of RNA polymerase II carboxyl terminus (CTD). | |||
TP1865 |
Rhodopsin Epitope Tag
|
||
Rhodopsin Epitope Tag is a 9-amino acid peptide representing C terminus of bovine rhodopsin widely used as an epitope tag. A number of anti-rhodopsin antibodies can recognize this epitope. | |||
T37767 |
Transdermal Peptide Disulfide TFA
|
||
Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA), an 11-amino acid peptide, specifically binds to the Na+/K+-ATPase beta-subunit (ATP1B1), predominantly interacting with its C-terminus. This compound is capable of enhancing the transdermal delivery of various macromolecules[1]. | |||
T80225 |
Bid BH3 (80-99), FAM labeled
|
||
Bid BH3 (80-99), FAM标记,是一种被5-FAM标记并具有生物活性的肽。 | |||
T40522 | 3'-Deoxy-3'-amino-ATP | ||
3'-Deoxy-3'-amino-ATP, an ATP analogue, is a highly effective and competitive inhibitor of ATP, exhibiting a K i value of 2.3 μM. Its application includes the synthesis of 3′-Amino-3′-deoxy transfer RNA by integrating it into the 3' terminus of tRNA-C-C. | |||
TP1435 |
Chemerin-9 (149-157) TFA(676367-27-4 free base)
Chemerin-9 (149-157) (TFA) |
||
Chemerin-9 (149-157) TFA, the nonapeptide (149)YFPGQFAFS(157) (chemerin-9), corresponding to the C terminus of processed chemerin, retains most of the activity of the full-size protein, with regard to agonism toward the chemerinR[1]. | |||
TP1707 |
LL-37, acetylated,amidated
|
||
This LL-37 peptide is acetylated on the N-terminus and amidated on the C-terminus.It plays a key role in the first line of defense against local infection and systemic invasion of pathogens at sites of inflammation and wounds. | |||
TP2299 |
tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]
|
Others | Others |
Tumor protein p53 binding protein (53BP1) has been identified in a yeast two-hybrid screen as a protein that interacts with the central DNA–binding domain of p532. Similar to breast cancer susceptibility gene 13, 4 (BRCA1; 53BP1 enhances p53-dependent tra | |||
T75966 |
C3a (70-77) (TFA)
|
||
C3a (70-77) TFA (Complement 3a (70-77) TFA) 为COOH末端对应C3a的八肽,具有C3a的特异性且生物活性约为1至2%。 | |||
TP1617 |
Chemerin-9 (149-157)
Chemerin-9 149-157 |
||
The nonapeptide 149,YFPGQFAFS157 (chemerin-9), corresponding to the C terminus of processed chemerin, retained most of the activity of the full-size protein, with regard to agonism toward the chemerinR.the natural ligand of ChemR23 (chemerinR). | |||
TP1585 |
sgp91 ds-tat Peptide 2, scrambled
|
||
This peptide is a scrambled sequence of NADPH oxidase assembly peptide inhibitor gp91 ds-tat. It is used as a control peptide. It is two amino acid residues shorter at the N-terminus compared to the scrambled gp91 ds-tat. | |||
T81437 |
PLTX-II
|
||
PLTX-II为一种肽类钙通道抑制剂,含44个氨基酸残基,其中10个为Cys残基,并在羧基末端具O-棕榈酰化的苏氨酸酰胺。 | |||
T76483 |
[Sar4] Substance P (4-11)
|
||
[Sar4] Substance P (4-11)为Substance P (4-11)的类似物,后者是Substance P (Substance P) C端片段并充当Substance P激动剂。 | |||
TP1033 |
Transdermal Peptide Disulfide
Transdermal Peptide,TD 1 (peptide) |
||
Transdermal Peptide (TD 1 peptide) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Pep | |||
TP1945 |
Pep2m, myristoylated
|
||
Cell-permeable, myristoylated form of pep2m. Peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF), a protein that regulates AMPA receptor function. Reduces pos | |||
T77162 | Donanemab | ||
Donanemab (LY3002813)为针对N末端焦谷氨酸β淀粉样蛋白(Aβ)表位的人源化IgG1单克隆抗体, 具潜力于早期阿尔茨海默病研究。 | |||
TP1944 |
pep2-SVKI
|
||
Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and | |||
T36338 |
AAF-CMK (trifluoroacetate salt)
|
||
Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at 50 μM. | |||
T76480 |
Amylin (1-37) (human)
|
||
Amylin (1-37) (human) (hIAPP (1-37)) 为胰岛β细胞分泌颗粒中的肽类激素,其C端经酰胺化处理,第2和第7个半胱氨酸残基间形成二硫键。 | |||
TP1130 |
β-CGRP, human
CGRP-II (Human),Human β-CGRP |
||
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at the N-terminus, a C-terminal phenylal | |||
T37532 |
Docosahexaenoyl Glycine
|
||
The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus. |