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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5052 |
Toltrazuril (sulfone)
Toltrazuril sulfone,妥曲珠利砜,Ponazuril |
Parasite | Microbiology/Virology |
Toltrazuril sulfone (Ponazuril) 是 Toltrazuril 的代谢物,是一种抗原生动物剂。它是一种三嗪类抗球虫剂,用于预防家禽球虫病。 | |||
T12309 |
Omeprazole metabolite Omeprazole sulfone
Omeprazole sulphone,Omeprazole sulfone |
Others | Others |
Omeprazole metabolite Omeprazole sulfone 是Omeprazole 的代谢物,能够抑制质子泵。 | |||
T20155 |
Lansoprazole sulfone
|
Others | Others |
Lansoprazole sulfone 是胃泵抑制剂Lansoprazole 的代谢产物。 | |||
T23403 |
Sulindac sulfone
|
Reductase; COX | Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Neuroscience |
Sulindac sulfone 是非甾体抗炎药舒林酸 (sulindac) 的代谢物。 它是醛糖还原酶的抑制剂 (IC50 =367 nM)。 | |||
T7640 |
Aldicarb sulfone
得灭克,丁醛肟威,涕灭威砜 |
AChE | Neuroscience |
Aldicarb sulfone 是一种氨基甲酸酯类杀虫剂,是一种胆碱酯酶抑制剂,能够抑制在突触乙酰胆碱的分解。 | |||
T24051 |
Exisulind
Sulindac sulfone,CP248 |
Apoptosis; PKA | Apoptosis; Tyrosine Kinase/Adaptors |
Exisulind (CP248) 通过激活蛋白激酶 G (PKG) 诱导细胞凋亡。 Exisulind 在实体瘤和血液癌细胞系中表现出抗肿瘤活性,并且是结肠癌、前列腺癌、膀胱癌、乳腺癌和肺癌啮齿动物模型中肿瘤生长的抑制剂。 | |||
T39225 |
Bis-sulfone-PEG3-Azide
Bis-sulfone-PEG3-Azide |
||
Bis-sulfone-PEG3-Azide, a cleavable ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs). | |||
T39297 |
Bis-sulfone-PEG4-DBCO
Bis-sulfone-PEG4-DBCO |
||
Bis-sulfone-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T32681 |
Leukotriene F-4 sulfone
Ltf4 sulfone |
||
Leukotriene F-4 sulfone induces vascular permeability changes. | |||
T0891 |
Dapsone
DDS,4,4‘-Sulfonyldianiline,氨苯砜,Bis(4-aminophenyl) sulfone,Sulphadione,4,4'-Diaminodiphenylsulfone,4-Aminophenyl sulfone |
Reactive Oxygen Species; Antibacterial; Antibiotic; Parasite | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Dapsone (Sulphadione) 是具有口服活性和血脑渗透通透性的磺酰类抗生素,具有抑菌、抗细菌和抗原虫活性。它有抗麻风活性,抑制麻风杆菌细胞提取物中叶酸的合成。它可研究皮肤病。 | |||
T37875 |
Fenbendazole sulfone
|
||
Fenbendazole sulfone is a minor metabolite of the anthelmintic fenbendazole . Fenbendazole undergoes oxidation to form oxfendazole, which is further oxidized to form fenbendazole sulfone. | |||
T36530 |
Pantoprazole sulfone
|
||
Pantoprazole sulfone is a metabolite of the gastric H+/K+ ATPase pump inhibitor pantoprazole . Pantoprazole is metabolized by the cytochrome P450 (CYP) isoforms CYP2C19 and CYP3A4 to form pantoprazole sulfone. | |||
T21226 | Albendazole sulfone | ||
Albendazole sulfone, a metabolite of Albendazole, is an antibiotic, anthelmintic, and antiparisitic. | |||
T35034 | Vamidothion sulfone | ||
Vamidothion sulfone is a biochemical. | |||
T31522 |
Dipropyl sulfone
|
||
Dipropyl sulfone may function as an enhancer of heparin absorption in the intestine. | |||
T21071 |
Fipronil sulfone
|
||
Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor. | |||
T0026 |
Sulfalene
磺胺林,Sulfalene(SMPZ),Sulfalen,SMP2,Butadiene sulfone,AS-18908,Sulfametopyrazine,3-Sulfolene |
Antibacterial; Antibiotic; Parasite; Autophagy | Autophagy; Microbiology/Virology |
Sulfalene (SMP2) 是一种长效磺胺类抗生素,用于治疗慢性支气管炎、尿路感染和疟疾。 | |||
T70105 |
Chlorpromazine Sulfone Hydrochloride
|
||
Chlorpromazine Sulfone Hydrochloride is a metabolite of Chlorpromazine -- an anti-emetic and anti-psychotic agent. It may also be used as a potential N-methyltransferase inhibitor. | |||
T23586 |
5-Hydroxylansoprazole sulfone
AG1909,AG 1909,AG-1909 |
||
5-hydroxylansoprazole is an in vitro metabolism-dependent CYP2C19 inhibitor. | |||
T18188 |
m-PEG3-Sulfone-PEG3
|
Others | Others |
m-PEG3-Sulfone-PEG3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T32680 | Leukotriene E-4 sulfone | ||
Leukotriene E-4 sulfone is a synthetic leukotriene. | |||
T18581 |
Propargyl-peg3-sulfone-peg3-propargyl
|
Others | Others |
Propargyl-PEG3-sulfone-PEG3-propargyl is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T18187 |
m-PEG3-Sulfone-PEG3-Boc
|
Others | Others |
m-PEG3-Sulfone-PEG3-Boc is a polyethylene glycol (PEG)-derived proteolysis-targeting chimera (PROTAC) linker employed for the synthesis of PROTACs[1]. | |||
T18186 |
m-PEG3-Sulfone-PEG3-azide
|
Others | Others |
m-PEG3-Sulfone-PEG3-azide is a polyethylene glycol (PEG)-based linker widely employed in the synthesis of PROTACs, which stands for Proteolysis Targeting Chimeras[1]. | |||
T18189 |
m-PEG3-Sulfone-PEG4-propargyl
|
Others | Others |
m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker. It is utilized in the efficient synthesis of PROTACs, a class of heterobifunctional molecules designed to selectively target and degrade specific protein targets[1]. | |||
T18735 |
Sulfone-Bis-PEG4-acid
|
Others | Others |
Sulfone-Bis-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18586 |
Propargyl-PEG4-Sulfone-PEG4-acid
|
Others | Others |
Propargyl-PEG4-Sulfone-PEG4-acid serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1]. | |||
T18185 | m-PEG3-Sulfone-PEG3-acid | Others | Others |
m-PEG3-Sulfone-PEG3-acid is a polyethylene glycol (PEG)-based protein degradation utilizing targeted chimera (PROTAC) linker [1]. | |||
T17687 |
Boc-PEG4-sulfone-PEG4-Boc
|
Others | Others |
Boc-PEG4-sulfone-PEG4-Boc is a polyethylene glycol (PEG)-derived linker specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T17469 |
Azide-PEG3-Sulfone-PEG3-azide
|
Others | Others |
Azide-PEG3-Sulfone-PEG3-azide is a polyethylene glycol (PEG)-based bifunctional molecule, specifically designed as a PROTAC linker for the synthesis of PROTACs[1]. | |||
T14122 |
Active-mono-sulfone-PEG8-acid
|
Others | Others |
Active-mono-sulfone-PEG8-acid is a polyethylene glycol (PEG) derivative serving as a linker for PROTAC synthesis[1]. | |||
T17508 | Azido-PEG3-Sulfone-PEG4-Boc | Others | Others |
Azido-PEG3-Sulfone-PEG4-Boc is a polyethylene glycol (PEG)-based PROTAC linker, utilized for the synthesis of PROTACs[1]. | |||
T18587 |
Propargyl-PEG4-Sulfone-PEG4-Boc
|
Others | Others |
Propargyl-PEG4-Sulfone-PEG4-Boc is a polyethylene glycol (PEG)-based linker molecule for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T17507 | Azido-PEG3-Sulfone-PEG4-acid | Others | Others |
Azido-PEG3-Sulfone-PEG4-acid is a polyethylene glycol (PEG) derivative frequently employed as a linker in the construction of proteolysis targeting chimeras (PROTACs)[1]. | |||
T69187 |
Cenicriviroc Sulfone
|
||
Cenicriviroc Sulfone is a derivative of Cenicriviroc which is an experimental drug candidate for the treatment of HIV infection. It is an inhibitor of CCR2 and CCR5 receptors allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell. | |||
T29603 |
Acid Blue 120 parent
Sulfone cyanine,J269.396H |
||
Acid Blue 120 parent is a dye. | |||
T71710 |
Fulvestrant sulfone
|
||
Fulvestrant sulfone is a synthetic estrogen receptor antagonist. | |||
T74640 |
Ilaprazole sulfone
|
||
Ilaprazole sulfone 是Ilaprazole 的主要代谢物,主要由 CYP3A4/5 催化。Ilaprazole (IY-81149) 是一种口服活性质子泵抑制剂。 | |||
TMIH-0077 |
Albendazole sulfone-d3
|
||
Albendazole sulfone-d3 是 Albendazole sulfone 的氘代化合物。 | |||
T124301 | 5'-Methyl-Thioadenosine-sulfone | ||
5'-Methyl-Thioadenosine-sulfone 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124301。 | |||
T70104 |
Verubecestat tosylate
|
||
Verubecestat tosylate, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat tosylate is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat tosylate reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. | |||
T3202 |
Fluensulfone
MCW-2 |
Parasite | Microbiology/Virology |
Fluensulfone (MCW-2) 是一种新型杀线虫剂,可化学防治植物寄生线虫。 | |||
T23606 |
Acediasulfone
|
||
Acediasulfone is an antibiotic. It is used to treat ear infections. | |||
T66319 | 3,4,5,6-Tetrabromophenolsulfonephthalein | ||
3,4,5,6-Tetrabromophenolsulfonephthalein 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66319,CAS号为 77172-72-6。 | |||
T69240 | Pyroxasulfone | ||
Pyroxasulfone is an inhibitor of very-long-chain fatty acid biosynthesis. Pyroxasulfone is used to control grass weed species in pre-emergence in major field crops. | |||
T2112 |
Fexinidazole
非昔硝唑,HOE 239 |
Others; Parasite | Microbiology/Virology; Others |
Fexinidazole (HOE 239) 是具有口服活性的硝基咪唑抗锥虫药物。它显示出对布鲁氏杆菌亚种和菌株的杀锥虫活性,IC50值为 0.7-3.3 μM (0.2-0.9 μg/ml)。它具有用于因感染布鲁氏菌引起的人类昏睡病的潜力。 | |||
T6070 |
(E/Z)-Rigosertib sodium
N-[2-甲氧基-5-[[[2-(2,4,6-三甲氧基苯基)乙烯基]磺酰]甲基]苯基]甘氨酸钠盐,(E/Z) ON-01910 sodium |
PLK | Cell Cycle/Checkpoint |
ON-01910 是一种非 ATP 竞争性 PLK1 抑制剂(IC50 为 9 nM,在无细胞试验中)。它对 Plk2 的选择性高出 30 倍,对 Plk3 没有活性。 Rigosertib 抑制 PI3K/Akt 通路并激活氧化应激信号。 Rigosertib 可诱导多种癌细胞凋亡。它是一种合成的苄基苯乙烯基砜类似物,具有潜在的抗肿瘤活性。 | |||
T69183 |
APC-3316 tosylate
|
||
APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist. | |||
T69182 |
APC-3316 hydrochloride
|
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APC-3316 hydrochloride is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist. | |||
T68506 |
Briciclib Na
|
||
Briciclib Na inhibits benzylstyryl sulfone kinase and is use for the treatment of Cancer |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13581 |
Biotin sulfone
|
Endogenous Metabolite | Metabolism |
Biotin sulfone 是一个被分离的天然生物素代谢物。 | |||
TN6752 |
Dimethyl sulfone
|
Endogenous Metabolite | Metabolism |
Dimethyl sulfone 是内源性代谢产物的一种。 |