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Cat. No.	Product Name	Target	Signaling Pathways
T15684	L-689560	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	L-689560 是 N-甲基-D-天冬氨酸受体（NMDA）的有效拮抗剂，抑制 NMDA 甘氨酸结合位点。它用于研究 NMDA 受体在正常神经系统过程以及疾病中的作用，也广泛用作结合研究中的放射性标记配体，也。
T32237	Isoxaben EL 107,NA 8318,Isoxaben； EL 107； NA 8318	Cell wall	Immunology/Inflammation
	Isoxaben (EL 107) 是一种细胞壁生物合成的特异性抑制剂，常作为除草剂使用，可抑制放射性标记的葡萄糖掺入酸不溶性细胞壁部分。
T15629	JTE-013	Apoptosis; S1P Receptor; LPL Receptor	Apoptosis; GPCR/G Protein
	JTE-013 是一种选择性S1P2拮抗剂。它抑制放射性标记的 S1P 与人和大鼠 S1P2的特异性结合，IC50分别为 17 nM 和 22 nM。
T60336	CCR4 antagonist 3-1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR4 antagonist 3-1 是一种具有较低活性的趋化因子受体 4 (CCR4) 拮抗剂，对 [125I]TARC (胸腺和活化调节趋化因子) 具有抑制作用，IC50 值为 1.7 μM。CCR4 antagonist 3-1 对放射标记的[125I]TARC和巨噬细胞来源的趋化因子(MDC) 与 CEM 细胞表面的CCR4 受体的结合有抑制作用，并对 TARC 介导的 CEM 细胞的体外迁移有抑制作用，IC50 值为 6.4 μM。
T24014	Dotanoc DOTA-Nal3-octreotide,DOTA-NOC
	Dotanoc is a ligand to make gallium Ga 68-DOTANOC, which is a gallium Ga 68-radiolabeled analog of somatostatin.
T31787	Fet F-18 Fet F18,18F-Fluoroethyltyrosine,18F-FET
	Fet F-18 is an amino acid analog radiolabeled with fluorine F-18, a positron-emitting isotope, can be used as a tracer in positron emission tomography (PET).
T18926	Biotin-probe 1	Others	Others
	Biotin-probe 1 is a non-radiolabeled probe and can be applied to in situ hybridization.
T70599	Asem F-18
	Asem F-18 is a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor with PET .
T68873	Cornigerine
	Cornigerine is a natural product analog of colchicine produced by Colchicum cornigerum that inhibited tubulin polymerization both with and without microtubule-associated proteins, inhibited the binding of radiolabeled colchicine to tubulin, and stimulated tubulin-dependent GTP hydrolysis.
T80238	NODAGA-LM3 TFA
	NODAGA-LM3 TFA 是一种可用68Ga标记的SSTR2拮抗剂，适用于PET成像，专门针对SSTR阳性副神经节瘤进行成像诊断。
T35448	10-Thiastearic Acid
	Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools. 10-Thiastearic acid inhibits desaturation of radiolabeled stearate to oleate in rat hepatocytes and hepatoma cells by more than 80% at a concentration of 25 μM. This activity is associated with a hypolipidemic effect, making this 10-thiastearic acid a useful tool for evaluating new anti-obesity therapeutics.
T80157	DOTA-JR11
	DOTA-JR11为SSTR2生长抑素受体拮抗剂，能经68Ga标记，应用于神经内分泌肿瘤（NETs）配对成像研究。
T37275	2,3-dinor-11β-Prostaglandin F2α 2,3-dinor-11β-Prostaglandin F2α
	2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α wh...
T76253	WL12
	WL12是一种专门针对程序性死亡配体1 (PD-L1)的结合肽，可通过多种放射性核素标记，生成放射性示踪剂，用于评估肿瘤中PD-L1的表达情况。
T39545	MK-6884
	MK-6884, a positive allosteric modulator (PAM) of M4 muscarinic receptors, exhibits a high affinity (Ki = 0.19 nM). It is a valuable compound for the investigation of neurodegenerative diseases. Additionally, MK-6884 can be efficiently radiolabeled with carbon-11, enabling its use as a PET imaging agent.
T69712	Icapamespib HCl
	Icapamespib, also known as PU-HZ 151, is a heat shock protein 90 (HSP90) inhibitor. PU-HZ151 showed EC50 of 5 nM in the FP assay as compared to 11 nM for PU-H71 and a logD of 2.37 as compared to 1.21 for PU-H71. PU-HZ151 and radiolabeled PU-HZ151 showed selectivity for epichaperomes over the individual chaperome members. Icapamespib demonstrated the ability to productively engage the target in cells, mice, and humans.
T68714	Iobenguane I 131
	Iobenguane I 131 is a guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
T61087	THK-5105
	THK-5105为芳基喹啉衍生物，具备与tau原纤维高度结合的亲和力。它对tau蛋白聚集体及含tau的阿尔茨海默病(AD)脑匀浆显示出显著的结合能力。18F-THK-5105展现出作为tau成像PET探针的潜能。
T70865	BMY-42393
	BMY-42393 is orally active and selective platelet aggregation inhibitor. BMY-42393 is also a prostacyclin partial agonist that inhibited ADP, collagen and thrombin-induced platelet aggregation (IC50 range 0.3 - 2.0 microM). BMY-42393 stimulated platelet adenylate cyclase activity (EC50 = 25 nM). Platelets treated with BMY 42393 showed an elevation of cAMP levels and activation of cAMP-dependent protein kinase. BMY 42393 also inhibited thrombin-induced elevation of intracellular free calcium. B...
T75252	Gemcitabine triphosphate
	Gemcitabine triphosphate (dFdCTP) 是 Gemcitabine 在细胞内的两种核苷代谢产物的一种。另一种是活性二磷酸 (dFdDTP)。Gemcitabine triphosphate 能够作为放射性标记探针成像研究的标准物，用于识别对 Gemcitabine 的肿瘤，并评估 Gemcitabine 被细胞摄取和保留性质。
T83813	8-Azidoadenosine-5'-O-diphosphate sodium 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate
	8-Azidoadenosine-5'-O-diphosphate（8-azido-ADP）是ATP前体和嘌呤受体配体ADP的可点击形式。8-azido-ADP的放射性标记形式已被用作各种蛋白质的光亲和标签，包括从牛脑中分离的谷氨酸脱氢酶（GDH）同工酶，以及从兔网织红细胞中分离的真核翻译起始因子2（eIF2）和鸟苷核苷酸交换因子（GEF）。

化合物

Cat.No: T15684

Target: NMDAR, iGluR

Cat.No: T32237

Synonym: EL 107,NA 8318,Isoxaben； EL 107； NA 8318

Target: Cell wall

Cat.No: T15629

Target: Apoptosis, S1P Receptor, LPL Receptor

CCR4 antagonist 3-1

Cat.No: T60336

Target: CCR

Cat.No: T24014

Synonym: DOTA-Nal3-octreotide,DOTA-NOC

Cat.No: T31787

Synonym: Fet F18,18F-Fluoroethyltyrosine,18F-FET

Cat.No: T18926

Target: Others

Cat.No: T70599

Cat.No: T68873

Cat.No: T80238

10-Thiastearic Acid

Cat.No: T35448

Cat.No: T80157

2,3-dinor-11β-Prostaglandin F2α

Cat.No: T37275

Synonym: 2,3-dinor-11β-Prostaglandin F2α

Cat.No: T76253

Cat.No: T39545

Icapamespib HCl

Cat.No: T69712

Iobenguane I 131

Cat.No: T68714

Cat.No: T61087

Cat.No: T70865

Gemcitabine triphosphate

Cat.No: T75252

8-Azidoadenosine-5'-O-diphosphate sodium

Cat.No: T83813

Synonym: 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate

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