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Search Results for " pentacyclic triterpene "

5

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T38088	28-Deoxybetulin methyleneamine
	28-Deoxybetulin methyleneamine is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It has been used in the synthesis of triterpene derivatives with antiviral activity. 1.Nitz, T.J., Montalbetti, C., Mears, R., et al.Extended Triterpene Derivatives(2008)
T37038	Betulinic Acid propargyl ester
	Betulinic acid propargyl ester is a pentacyclic lupane triterpene and alkyne derivative of betulinic acid .1,2It has been used in click chemistry reactions for the synthesis of cytotoxic anticancer betulinic acid derivatives.
T35678	2,3-Indolobetulinic glycine amide
	2,3-Indolobetulinic glycine amide is a pentacyclic triterpene and derivative of betulinic acid .1It has been used in the synthesis of betulinic acid derivatives with anticancer activity. 1.Kumar, V., Rani, N., Aggarwal, P., et al.Synthesis and cytotoxic activity of heterocyclic ring-substituted betulinic acid derivativesBioorg. Med. Chem. Lett.18(18)5058-5062(2008)
T63092	Anti-inflammatory agent 12
	Anti-inflammatory agent 12 是一种五环三萜化合物，在 LPS 诱导的炎症反应中表现出显着的偏差 (IC50: 2.22 μM)。Anti-inflammatory agent 12 具有潜力用于炎症性疾病的研究。
T63061	Anti-inflammatory agent 13
	Anti-inflammatory agent 13 是一种五环三萜化合物，对炎症模型具有明显的抑制作用。Anti-inflammatory agent 13 具有潜力进行 DAMP 或 PAMP 引发炎症的研究。

化合物

28-Deoxybetulin methyleneamine

Cat.No: T38088

Betulinic Acid propargyl ester

Cat.No: T37038

2,3-Indolobetulinic glycine amide

Cat.No: T35678

Anti-inflammatory agent 12

Cat.No: T63092

Anti-inflammatory agent 13

Cat.No: T63061

Cat. No.	Product Name	Target	Signaling Pathways
TN2097	Pomolic acid 坡模酸	Apoptosis; Caspase; HIV Protease; AMPK	Apoptosis; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Pomolic acid 是从野鸦椿中分离出来的一种五环三萜烯。它抑制肿瘤细胞的生长，诱导细胞凋亡，有用于前列腺癌的潜力。
T2813	Madecassoside Asiaticoside A,羟基积雪草苷	Apoptosis; Antioxidant; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	Madecassoside (Asiaticoside A) 是从崩大碗中分离出来的一种五环三萜，有抗炎症，抗氧化和抗衰老的作用。
TN1111	Arnidiol	Immunology/Inflammation related	Immunology/Inflammation
	Arnidiol 是一种五环三萜烯，从Barleria Longiflora LinnF. 中提取得到。
T2830	Betulinic acid 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid	Apoptosis; Mitophagy; NF-κB; HIV Protease; Topoisomerase; Endogenous Metabolite; Aminopeptidase; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Betulinic acid (ALS-357) 是从白桦树皮中分离出来的一种五环三萜类天然产物，是真核细胞拓扑异构酶 I 的抑制剂，IC50值为 5 μM，具有抗逆转录病毒、抗疟疾、抗癌和抗炎特性。
T24884	Tingenone Maytenin,Maitenin,Tingenin A,Tingenon
	Tingenone is a pentacyclic triterpene. It induces peripheral antinociception due to opioidergic activation.
T13964	Waltonitone	Others	Others
	Waltonitone is a natural ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill.
T82747	Centellasaponin A
	Centellasaponin A (compound 10)为五环三萜皂苷类化合物，可通过积雪草甲醇提取物进行分离提取。
T82042	Isoasiaticoside
	Isoasiaticoside为五环三萜皂苷类化合物，可从积雪草(Centella asiatica)提取。该化合物在6-OHDA诱导的PC12细胞模型中显示出潜在神经保护效应。

天然产物

Cat.No: TN2097

Synonym: 坡模酸

Target: Apoptosis, Caspase, HIV Protease, AMPK

Cat.No: T2813

Synonym: Asiaticoside A,羟基积雪草苷

Target: Apoptosis, Antioxidant, Endogenous Metabolite

Cat.No: TN1111

Target: Immunology/Inflammation related

Cat.No: T2830

Synonym: 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid

Target: Apoptosis, Mitophagy, NF-κB, HIV Protease, Topoisomerase, Endogenous Metabolite, Aminopeptidase, Autophagy

Cat.No: T24884

Synonym: Maytenin,Maitenin,Tingenin A,Tingenon

Cat.No: T13964

Target: Others

Centellasaponin A

Cat.No: T82747

Isoasiaticoside

Cat.No: T82042

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