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Cat. No. Product Name Target Signaling Pathways
TD0098 Direct Red 80

Sirius Red,天狼猩红,Sirius Red F 3BA,C.I. direct red 80

Others Others
Direct Red 80 (Sirius Red) 是一种聚偶氮染料,在降解时不会释放联苯胺,比许多传统的直接染料更安全,主要用于胶原蛋白和淀粉样蛋白的染色方法。
T7460 α-Cyano-4-hydroxycinnamic acid

α-Cyano-4-hydroxycinnamic acid(α-CHCA),2-氰基-4-羟基

Monocarboxylate transporter Membrane transporter/Ion channel
α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) 是非竞争性单羧酸盐转运蛋白 (MCTs) 抑制剂,可抑制线粒体丙酮酸转运蛋白,Ki 值为 6.3 μM。它可作为基质辅助激光解吸电离-飞行时间质谱 (MALDI-TOF) 分析的基质,可以促进肽离子化。
T3338 Ceralasertib

AZD6738

ATM/ATR DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
Ceralasertib (AZD6738) 是一种具有口服活性的选择性 ATR 激酶抑制剂,IC50 为 1 nM。
T6019 Volasertib

BI 6727,伏拉塞替

Apoptosis; PLK Apoptosis; Cell Cycle/Checkpoint
Volasertib (BI 6727) 是一种具有口服活性的高效ATP 竞争性Polo 样激酶 1 抑制剂。它抑制 PLK2 和 PLK3,IC50分别为 5 和 56 nM。它是二氢蝶呤酮衍生物,有抗肿瘤活性,可诱导有丝分裂停滞和细胞凋亡。
T32577 Laserpitin

NSC-109434,NSC 109434,NSC109434

Laserpitin is a coumarin compound from Angelica keiskei.
T124156 Laserine oxide

Laserine oxide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124156,CAS号为 82433-10-1。
T32576 Laserolide

Laserolide is a sesquiterpene lactone.
T26981 Ceralasertib formate

Ceralasertib,AZD-6738,AZD 6738,AZD6738

Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-
T12795 (S)-Ceralasertib

(S)-AZD6738

Others Others
(S)-Ceralasertib is a potent and selective inhibitor of sulfoximine morpholinopyrimidine ATR with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. .
T125424 Laserine

Laserine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125424,CAS号为 19946-83-9。
T41100 Volasertib trihydrochloride

BI6727trihydrochloride,伏拉塞替三盐酸盐

Volasertib (BI 6727) trihydrochloride is a dihydropteridinone derivative that exhibits potent and selective inhibition of Polo-like kinase 1 (PLK1), PLK2, and PLK3. It acts as an orally active ATP-competitive inhibitor with an IC50 of 0.87 nM against PLK1. Additionally, Volasertib trihydrochloride demonstrates IC50 values of 5 nM and 56 nM against PLK2 and PLK3, respectively. Its mechanism of action includes inducing mitotic arrest and apoptosis. Furthermore, Volasertib trihydrochloride has been...
T126023 d-Laserpitin

d-Laserpitin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126023。
T19063 Sulforhodamine B sodium salt

Acid Red 52,Kiton Red 620,磺酰罗丹明B

Others Others
Sulforhodamine B sodium salt (Acid Red 52) 是一种能够定量测定培养细胞的细胞蛋白量的荧光染料,。
T16744 Rhodamine 6G

Basic Red 1,罗丹明6G,罗丹明 6G

Others Others
Rhodamine 6G (Basic Red 1) 是一种罗丹明类似物,可用于表征 MRP1 介导的流出的动力学,测定 Pgp 的流出,可用作激光染料和潜在的线粒体探针。
T3316 Fluorometholone

氟米龙,Fluoromethalone,Cortilet,Oxylone,Delmeson

Glucocorticoid Receptor Endocrinology/Hormones
Fluorometholone (Fluoromethalone) 是合成糖皮质激素,具有抗炎和抗过敏作用。它可用作糖皮质激素受体激动剂,能够用于干眼症的研究。
T14050 5-FAM

5-羧基荧光素,5-Carboxyfluorescein

Others Others
5-FAM (5-Carboxyfluorescein) 是一种绿色荧光探针(Ex/Em 为 490 nm/520 nm),可用于肽,蛋白质和核苷酸的标记。
T36466 Chlorin E6

Ce6,Chlorin e6,CE6

Parasite Microbiology/Virology
Chlorin E6 (CE6) 是一种第二代光敏剂,在与辐照结合使用时具有抗肿瘤活性。在植入性纤维肉瘤的小鼠模型中,Chlorin E6(2.5-10 毫克/千克,静脉注射,50-200 焦耳/平方厘米的辐照)在不同程度的辐照后会导致肿瘤完全消失。在一项针对支气管源性早期浅表鳞状细胞癌患者的 I 期临床研究中,对包括 Chlorin E6 在内的制剂进行了测试,结果良好(40 毫克/平方米,静脉注射,100 焦耳/平方厘米的激光辐照)。在一项针对早期肺癌患者的二期临床试验中,同样的给药模式使 82.9% 的患者获得了完全应答。Chlorin E6 已被研究为一种纳米技术给药工具。
T16743L Rhodamine 123 free base

The laser dye rhodamine 123 inhibit mitochondrion function.
T20664 LD 490

C 6H,C-6H,LD-490,LD490,C6H

LD 490 is a laser dye.
T32616 LD-473

LD 473

LD-473 is a laser dye.
T82195 HITCI

HITCI作为具有正电荷的商业化吲哚碳菁染料,常用于近红外(NIR)激光染料应用场合。
T37090 Indo-1 (potassium salt)

Indo-1 is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when indo-1 binds calcium. Indo-1 is prone to photobleaching, which limits its usefulness in methods involving microscopy.
TD0029 Super Fluor 750

Super Fluor 750 dye is a bright, near-IR–fluorescent dye with excitation ideally suited for the 633 nm laser line or dye-pumped laser excitation. Super Fluor 750 dye is pH-insensitive over a wide molar range, helping ensure that you get stable signals in
T78089 FITC-labeled ODN 1018 sodium

FITC-labeled ODN 1018 (sodium) 作为TLR9激动剂,其细胞内摄取和定位可通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术进行评估。
T67840 5-TAMRA Azide

TAMRA Azide, isomer 5

Others Others
5-TAMRA Azide (TAMRA Azide, isomer 5) 是一种橙色荧光探针,兼容各种激发源,包括汞弧灯,钨弧灯和氙弧灯,氦氖激光544 nm 线和532 nm 绿激光线。它主要用于检测末端炔标记的生物分子通过铜催化的点击反应(CuAAC)。
T37317 Fluo-3 (sodium salt)

Fluo-3 is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
T78457 Pyrromethene 597

Pyrromethene 597 是一种具有宽波长调谐范围及高光稳定性的 BODIPY 激光染料,可作为热探针使用。
T74601 Antitumor photosensitizer-3

Antitumor photosensitizer-3(Compound I)是一种二氢卟酚衍生物,能在650 nm激光照射下诱导肿瘤细胞的凋亡和坏死。与阳性参考m-THPC相比,Antitumor photosensitizer-3在体内的皮肤光毒性较低。
T78996 FITC-labeled ODN 2088 sodium

FITC-labeled ODN 2088 (sodium) 作为TLR3、TLR7和TLR9的抑制剂,可用于评估CpG ODN在细胞内的摄取与定位。通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术进行检测。
TD0025 Super Fluor 647

Super Fluor 647 dye is a bright, far-red–fluorescent dye with excitation ideally suited for the 594 nm or 633 nm laser lines. For stable signal generation in imaging and flow cytometry, Super Fluor 647 dye is pH-insensitive over a wide molar range.Probes
TD0027 Super Fluor 680

Super Fluor 680 dye is a bright, near-IR fluorescent dye with excitation ideally suited for the 633 nm laser line. For stable signal generation in imaging and flow cytometry, Super Fluor 680 dye is pH-insensitive over a wide molar range.The fluorescence q
T78998 FITC-labeled ODN 2216 sodium

FITC-labeled ODN 2216 (sodium) 为TLR9激动剂,其细胞摄取与定位可通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术评估。
T82391 Fluo-3

Fluo-3及其相关化合物Fluo3/AM作为细胞内钙(Ca2+)的荧光指示剂。Fluo-3可用于可见光激发(与波长为488 nm的氩离子激光光源兼容)的流式细胞术和共聚焦激光扫描显微镜研究。与钙结合后,荧光强度可增加约40倍。
T78665 FITC-labeled ODN 1826 sodium

FITC-labeled ODN 1826(sodium)为B类CpG ODN,兼作TLR9激动剂。该化合物的细胞摄取和定位可通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)及流式细胞术进行评估。
T37316 Fluo-3 (potassium salt)

Fluo-3 (potassium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
T78663 FITC-labeled Agatolimod sodium

FITC-labeled Agatolimod (sodium) 是一种B类CpG ODN,兼具TLR9激动剂功能。该化合物应用共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术,可以评估CpG ODN在细胞内的摄取及定位情况。
T83482 1,1',3,3,3',3'-Hexamethylindotricarbocyanine perchlorate

HITC

1,1',3,3,3',3'-Hexamethylindotricarbocyanine perchlorate (HITC)为一种长波长染料,对膜电位具有敏感性。该化合物作为电位计荧光素表现出缓慢的反应性,并用作红外激光器中的激光染料。
T78992 FITC-labeled ODN 1585 sodium

FITC-labeled ODN 1585 (sodium) 为B类CpG ODN同时兼作TLR9激动剂。通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术,可评估其细胞内摄取和定位情况。
T78994 FITC-labeled ODN 1668 sodium

FITC-labeled ODN 1668 (sodium) 是B类CpG ODN,兼具TLR9激动剂功能。该化合物能借助共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)及流式细胞术,用于评估CpG ODN在细胞内的摄取及定位情况。
T37091 Indo-1 (sodium salt)

Indo-1 is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when indo-1 binds calcium. Indo-1 is prone to photobleaching, which limits its usefulness in methods involving microscopy.
T79000 FITC-labeled ODN 2395 sodium

FITC-labeled ODN 2395 (sodium) 是C类CpG ODN,具有TLR9激动剂功能。该化合物的细胞摄取和定位可通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术进行评估。
T37315 Fluo-3 (ammonium salt)

Fluo-3 (ammonium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. [1] Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
TD0021 Super Fluor 488

Super Fluor 488 dye is a bright, green-fluorescent dye with excitation ideally suited to the 488 nm laser line. For stable signal generation in imaging and flow cytometry, Super Fluor 488 dye is pH-insensitive over a wide molar range.Probes with high fluo
T79002 FITC-labeled ODN TTAGGG sodium

FITC-labeled ODN TTAGGG (sodium) 作为一种寡核苷酸抑制剂,对TLR9、AIM2及cGAS具有拮抗作用。通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术,可以评估CpG ODN在细胞内的摄取及定位情况。
T41209 DPNB-ABT 594

DPNB-ABT 594 is a nitrobenzyl-caged ABT 594, a selective α4β2 nAChR agonist. One-photon uncaging evokes large inward currents and Ca2+transients on cell bodies and dendrites of medial habenular neurons in mouse brain slices. Two-photon uncaging induces fast nAChR-mediated currents. Photolyzed with high quantum yield of 0.20. Effective photolysis occurs using one- or two-photon excitation; one-photon uncaging requires illumination at 410 nm for 1.5-3 ms; two-photon uncaging requires illumination ...
T36908 Bimatoprost grenod

15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α

Bimatoprost grenod(15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α) is a nitric oxide-donating derivative of 17-phenyl trinor PGF2α.1It increases cGMP levels in rabbit aqueous humor and iris ciliary body when topically administered at a concentration of 0.042%. Topical administration of 15-(6-nitroxylhexanoyl)-17-phenyl trinor PGF2α(0.14%) reduces intraocular hypertension (IOP) in a rabbit model of hypertonic saline-induced transient ocular pressure. It also reduces IOP in a cynomolgus monkey mode...
T34112 Porfimer Sodium

DHE,dihematoporphyrin ether,CL184116,CL-184116,CL 184116,Porfimer

Porfimer sodium is t he sodium salt of a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units with photodynamic activity. Absorbed selectively by tumor cells, porfimer produces oxygen radicals after activation by 630 nm w
T35494 (±)11(12)-EET

(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms CYP2C23 and CYP2C24 while CYP2B2 produces a higher proportion of 11(S),12(R)-EET.[3]11(12)-EET has been shown, along with 8(9)-EET to play a role in the recovery of depleted calcium pools in cultured smooth muscle cells[4] It also inhibits basolateral 18-pS potassium channels in t...
T36364 Flutax-2

Green fluorescent taxol derivative. Used for microtubule imaging. Binds microtubules with high affinity (Ka ~ 107M-1). Excitation/emission maximum λ ~ 496/526 nm. Lillo et al (2002) Location and properties of the Tax. binding center in microtubules: a picosecond laser study with fluorescent taxoids. Biochemistry. 41 12436 PMID:12369834 |Diaz et al (2000) Molecular recognition of Tax. by microtubules. Kinetics and thermodynamics of binding of fluorescent Tax. derivatives to an exposed site. J.Bio...

化合物

Direct Red 80
Cat.No: TD0098
Synonym: Sirius Red,天狼猩红,Sirius Red F 3BA,C.I. direct red 80
Target: Others
α-Cyano-4-hydroxycinnamic acid
Cat.No: T7460
Synonym: α-Cyano-4-hydroxycinnamic acid(α-CHCA),2-氰基-4-羟基
Target: Monocarboxylate transporter
Ceralasertib
Cat.No: T3338
Synonym: AZD6738
Target: ATM/ATR
Volasertib
Cat.No: T6019
Synonym: BI 6727,伏拉塞替
Target: Apoptosis, PLK
Laserpitin
Cat.No: T32577
Synonym: NSC-109434,NSC 109434,NSC109434
Target:
Laserine oxide
Cat.No: T124156
Synonym:
Target:
Laserolide
Cat.No: T32576
Synonym:
Target:
Ceralasertib formate
Cat.No: T26981
Synonym: Ceralasertib,AZD-6738,AZD 6738,AZD6738
Target:
(S)-Ceralasertib
Cat.No: T12795
Synonym: (S)-AZD6738
Target: Others
Laserine
Cat.No: T125424
Synonym:
Target:
Volasertib trihydrochloride
Cat.No: T41100
Synonym: BI6727trihydrochloride,伏拉塞替三盐酸盐
Target:
d-Laserpitin
Cat.No: T126023
Synonym:
Target:
Sulforhodamine B sodium salt
Cat.No: T19063
Synonym: Acid Red 52,Kiton Red 620,磺酰罗丹明B
Target: Others
Rhodamine 6G
Cat.No: T16744
Synonym: Basic Red 1,罗丹明6G,罗丹明 6G
Target: Others
Fluorometholone
Cat.No: T3316
Synonym: 氟米龙,Fluoromethalone,Cortilet,Oxylone,Delmeson
Target: Glucocorticoid Receptor
5-FAM
Cat.No: T14050
Synonym: 5-羧基荧光素,5-Carboxyfluorescein
Target: Others
Chlorin E6
Cat.No: T36466
Synonym: Ce6,Chlorin e6,CE6
Target: Parasite
Rhodamine 123 free base
Cat.No: T16743L
Synonym:
Target:
LD 490
Cat.No: T20664
Synonym: C 6H,C-6H,LD-490,LD490,C6H
Target:
LD-473
Cat.No: T32616
Synonym: LD 473
Target:
HITCI
Cat.No: T82195
Synonym:
Target:
Indo-1 (potassium salt)
Cat.No: T37090
Synonym:
Target:
Super Fluor 750
Cat.No: TD0029
Synonym:
Target:
FITC-labeled ODN 1018 sodium
Cat.No: T78089
Synonym:
Target:
5-TAMRA Azide
Cat.No: T67840
Synonym: TAMRA Azide, isomer 5
Target: Others
Fluo-3 (sodium salt)
Cat.No: T37317
Synonym:
Target:
Pyrromethene 597
Cat.No: T78457
Synonym:
Target:
Antitumor photosensitizer-3
Cat.No: T74601
Synonym:
Target:
FITC-labeled ODN 2088 sodium
Cat.No: T78996
Synonym:
Target:
Super Fluor 647
Cat.No: TD0025
Synonym:
Target:
Super Fluor 680
Cat.No: TD0027
Synonym:
Target:
FITC-labeled ODN 2216 sodium
Cat.No: T78998
Synonym:
Target:
Fluo-3
Cat.No: T82391
Synonym:
Target:
FITC-labeled ODN 1826 sodium
Cat.No: T78665
Synonym:
Target:
Fluo-3 (potassium salt)
Cat.No: T37316
Synonym:
Target:
FITC-labeled Agatolimod sodium
Cat.No: T78663
Synonym:
Target:
1,1',3,3,3',3'-Hexamethylindotricarbocyanine perchlorate
Cat.No: T83482
Synonym: HITC
Target:
FITC-labeled ODN 1585 sodium
Cat.No: T78992
Synonym:
Target:
FITC-labeled ODN 1668 sodium
Cat.No: T78994
Synonym:
Target:
Indo-1 (sodium salt)
Cat.No: T37091
Synonym:
Target:
FITC-labeled ODN 2395 sodium
Cat.No: T79000
Synonym:
Target:
Fluo-3 (ammonium salt)
Cat.No: T37315
Synonym:
Target:
Super Fluor 488
Cat.No: TD0021
Synonym:
Target:
FITC-labeled ODN TTAGGG sodium
Cat.No: T79002
Synonym:
Target:
DPNB-ABT 594
Cat.No: T41209
Synonym:
Target:
Bimatoprost grenod
Cat.No: T36908
Synonym: 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α
Target:
Porfimer Sodium
Cat.No: T34112
Synonym: DHE,dihematoporphyrin ether,CL184116,CL-184116,CL 184116,Porfimer
Target:
(±)11(12)-EET
Cat.No: T35494
Synonym:
Target:
Flutax-2
Cat.No: T36364
Synonym:
Target:
TargetMol Loading
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