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Rhodamine 6G

产品编号 T16744 CAS 989-38-8

别名: Basic Red 1, 罗丹明6G, 罗丹明 6G

Rhodamine 6G (Basic Red 1) 是一种罗丹明类似物，可用于表征 MRP1 介导的流出的动力学，测定 Pgp 的流出，可用作激光染料和潜在的线粒体探针。

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Rhodamine 6G, CAS 989-38-8

规格	价格/CNY	货期
5 mg	￥ 99	现货
25 mg	￥ 137	现货
50 mg	￥ 183	现货
100 mg	￥ 249	现货
500 mg	￥ 522	现货
1 g	￥ 662	现货
5 g	￥ 972	现货
10 g	￥ 1,430	现货
1 mL * 10 mM (in DMSO)	￥ 455	现货

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选择批次

纯度: 99.18%

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生物活性

化学信息

存储 & 溶解度

参考文献

产品描述	Rhodamine 6G (Basic Red 1) is a rhodamine analog useful in Pgp efflux assays. It can be widely used in characterizing the kinetics of MRP1- mediated efflux as a laser dye and potential mitochondrial probe.
体外活性	Rhodamine 6G, also known as Rhodamine 590, is widely used as a lasing medium and as a fluorescence tracer. Rhodamine 6G is a fluorescent dye capable of penetrating a living cell. Upon entering the cell, Rhodamine 6G binds to the inner membranes of mitochondria. Based on these observations, it has been proposed that Rhodamine dyes may be used for producing fluorescent images of mitochondria with low background noise and high resolution. Extremely low concentrations of Rhodamine 6G appear to selectively destroy malignant cells in culture, sparing the normal cell populations[2].
体内活性	Compared to their untreated counterparts, Melanoma-transplanted mice receiving Rhodamine 6G demonstrate prolonged survival, inhibited tumor growth, improved clinical parameters and metastases count. It is possible to monitor changes in the interactions between leukocytes and the endothelium by determining the numbers of rolling and adhering leukocytes as well as the total flux of these cells[3]. The Rhodamine-6G enters the circulatory system and labels leukocytes. Twice-a-week 10-6M Rhodamine 6G regimen yield the most prominent results[2].

别名	Basic Red 1, 罗丹明6G, 罗丹明 6G
分子量	479.01
分子式	C28H31ClN2O3
CAS No.	989-38-8

存储

keep away from direct sunlight　|　Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

H2O: 83.3 mg/mL (173.97 mM), Sonication is recommended.

DMSO: 7.5 mg/mL (15.66 mM), Sonication is recommended.

溶液配制表

可选溶剂	浓度体积质量	1 mg	5 mg	10 mg	25 mg
H2O / DMSO	1 mM	2.0876 mL	10.4382 mL	20.8764 mL	52.191 mL
	5 mM	0.4175 mL	2.0876 mL	4.1753 mL	10.4382 mL
	10 mM	0.2088 mL	1.0438 mL	2.0876 mL	5.2191 mL
H2O	20 mM	0.1044 mL	0.5219 mL	1.0438 mL	2.6095 mL
	50 mM	0.0418 mL	0.2088 mL	0.4175 mL	1.0438 mL
	100 mM	0.0209 mL	0.1044 mL	0.2088 mL	0.5219 mL

计算器

摩尔浓度计算器

稀释计算器

配液计算器

分子量计算器

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浓度 (终)

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参考文献

1. Zehentbauer FM, et al. Fluorescence spectroscopy of Rhodamine 6G: concentration and solvent effects. Spectrochim Acta A Mol Biomol Spectrosc. 2014;121:147-51. 2. Kutushov M, et al. Low concentrations of Rhodamine 6G selectively destroy tumor cells and improve survival of melanoma transplanted mice. Neoplasma. 2013;60(3):262-73. 3. Jain RK, et al. Measuring leukocyte-endothelial interactions in mice. Cold Spring Harb Protoc. 2013 Jun 1;2013(6):561-3.

剂量换算

对于不同动物的给药剂量换算，您也可以参考 更多...

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10 只，您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL)，如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法：取 50 μL DMSO 主液，加入 300 μL PEG300，混匀澄清，再加 50 μL Tween 80，混匀澄清，再加 600 μL ddH2O, 混匀澄清。

第一步：请输入动物实验的基本信息

剂量

mg/kg

每只动物体重

给药体积

μL

动物数量

第二步：请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。

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