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Search Results for " lactic "

19

抑制剂 & 化合物

17

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5230	DL-Indole-3-lactic acid	Others	Others
	DL-Indole-3-lactic acid 是制备抗菌剂的反应物。
T41001	L-Lactic acid-13C3 L-Lactic acid-13C3,(S)-2-hydroxypropanoic-13-C3
	L-Lactic acid-13C3 is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-13C3 can be used for lactate metabolism research.
T19521	PLGA poly(lactic-co-glycolic acid),聚乳酸-羟基乙酸共聚物	Others	Others
	PLGA (poly(lactic-co-glycolic acid)) 是一种聚乳酸和聚乙醇酸的共聚物，能够制造用于药物递送和组织工程应用的装置。
T40923	Calcium lactate Lactic acid calcium,Hemicalcium L-lactate,Lactate calcium,乳酸钙,Conclyte calcium	Others	Others
	Calcium lactate (Conclyte calcium) 被饮料工业用作强化果汁的钙源。Calcium lactate 促进豆芽生长和植酸降解。
T33870	Palmitoyllactic acid Lactic acid,palmitate
	Palmitoyllactic acid is a long-chain fatty acid.
T33871	Palmitoyllactic acid, (S)- L-2-o-palmitoyllactic acid
	Palmitoyllactic acid, (S)- is a bioactive chemical.
T32528	Lacticolorin
	Lacticolorin is a phenolic glucoside ester; metabolite of Protea lacticolor Salisb.
T6193	Dovitinib Dilactic Acid Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic acid	VEGFR; FGFR; FLT; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	Dovitinib Dilactic Acid (Dovitinib(TKI-258) Dilactic Acid) 是 Dovitinib 的双乳酸，是一种多靶点 RTK 抑制剂，主要用于 III 类 (FLT3/c-Kit)，IC50 为 1 nM/2 nM，对 IV 类 (FGFR1/ 3) 和 V 类 (VEGFR1-4) RTK，IC50 为 8-13 nM，对 InsR、EGFR、c-Met、EphA2、Tie2、IGFR1 和 HER2 的效力较低。
TP1329	Nisin	Antibacterial; Antibiotic	Microbiology/Virology
	Nisin 是乳酸链球菌肽，由一组属于乳球菌和链球菌属的革兰氏阳性菌产生。
T4103	(L)-Sodium lactate L-乳酸钠,Sodium L-Lactate	Others	Others
	(L)-Sodium lactate (Sodium L-Lactate) 是由乳酸脱氢酶从丙酮酸中产生的。它在无氧糖酵解过程中或增殖活跃的细胞中产生。它在人和动物的血液和肌肉液中少量存在。剧烈运动后，肌肉和血液中的乳酸浓度会增加。它也存在于肝脏、肾脏、胸腺、人羊水以及其他器官和体液中。
T20416	Phenylphosphinic acid NSC 2670,NSC2670,苯膦酸,NSC-2670	Others	Others
	Phenylphosphinic acid (NSC-2670) 是一种与野依氏催化剂一起使用的添加剂，可提高聚乳酸的阻燃性。Phenylphosphinic acid 可用于将硫化物氧化成砜。
T39862	Trimethoprim lactate
	Trimethoprim lactic is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim lactic is active against a wide range of Gram-positive and Gram-negative aerobic bacteria . Trimethoprim lactic has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment.
T32809	L-Lactate ion L-Lactate,Lactate ion, L-
	L-Lactate ion is the conjugate base of lactic acid.
T25281	Cyclopeptolide 1 SDZ 90-215,Cyclopeptolide-1
	Cyclopeptolide 1 is a novel antifungal cyclopeptolide. Cyclopeptolide 1 is similar to cyclosporin A that consists of nine S-amino acids and R-lactic acid.
T20316	Calcium stearate AI3 01335,AI3-01335,AI301335
	Calcium Stearate is a potent Alternative to Poly(vinyl alcohol) in Poly-Lactic-co-Glycolic Acid Nanoparticles Synthesis.
T13538	AlbA-DCA	ROS	Immunology/Inflammation
	AlbA-DCA is a conjugate formed by the attachment of Albiziabioside A to a dichloroacetate acid subunit. It can induce a marked increase in intracellular ROS and alleviate the accumulation of lactic acid in the tumor microenvironment, and also selectively
T78225	3-Butynoic acid	Endogenous Metabolite	Metabolism
	3-Butynoic acid 是一种有效的酰基辅酶A脱氢酶 (acyl CoA dehydrogenase) 抑制剂，是Zn依赖性黄素酶D-乳酸脱氢酶的底物，可用于研究乳酸代谢。
T73930	(-)-Eseroline fumarate
	(-)-Eseroline fumarate 是一种 AChE 抑制剂 Physostigmine 的代谢产物。(-)-Eseroline fumarate 引起癌细胞的乳酸脱氢酶 (LDH) 泄漏。(-)-Eseroline fumarate 还诱导神经元细胞释放腺嘌呤核苷酸和5-羟色胺 (5-HT)，从而诱导细胞死亡。(-)-Eseroline fumarate 抑制小鼠输精管和豚鼠回肠的电诱发抽搐。
T83849	OP-145 TFA acetyl-IGKEFKRIVERIKRFLRELVRPLR-amide,P60.4-Ac
	OP-145是一种合成抗菌肽及抗菌肽LL-37的衍生物。它对E. coli、P. aeruginosa、C. albicans和A. niger具有活性（MICs分别为2、3、6和18 µM）。含有OP-145的聚乳酸-共-聚乙二醇酸（PLGA）微球能够在骨折部位接种细菌后通过外科股骨骨折所诱导的小鼠骨感染模型中防止生物膜的形成。

化合物

DL-Indole-3-lactic acid

Cat.No: T5230

Target: Others

L-Lactic acid-13C3

Cat.No: T41001

Synonym: L-Lactic acid-13C3,(S)-2-hydroxypropanoic-13-C3

Cat.No: T19521

Synonym: poly(lactic-co-glycolic acid),聚乳酸-羟基乙酸共聚物

Target: Others

Calcium lactate

Cat.No: T40923

Synonym: Lactic acid calcium,Hemicalcium L-lactate,Lactate calcium,乳酸钙,Conclyte calcium

Target: Others

Palmitoyllactic acid

Cat.No: T33870

Synonym: Lactic acid,palmitate

Palmitoyllactic acid, (S)-

Cat.No: T33871

Synonym: L-2-o-palmitoyllactic acid

Cat.No: T32528

Dovitinib Dilactic Acid

Cat.No: T6193

Synonym: Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic acid

Target: VEGFR, FGFR, FLT, c-Kit

Cat.No: TP1329

Target: Antibacterial, Antibiotic

(L)-Sodium lactate

Cat.No: T4103

Synonym: L-乳酸钠,Sodium L-Lactate

Target: Others

Phenylphosphinic acid

Cat.No: T20416

Synonym: NSC 2670,NSC2670,苯膦酸,NSC-2670

Target: Others

Trimethoprim lactate

Cat.No: T39862

Cat.No: T32809

Synonym: L-Lactate,Lactate ion, L-

Cyclopeptolide 1

Cat.No: T25281

Synonym: SDZ 90-215,Cyclopeptolide-1

Calcium stearate

Cat.No: T20316

Synonym: AI3 01335,AI3-01335,AI301335

Cat.No: T13538

Target: ROS

3-Butynoic acid

Cat.No: T78225

Target: Endogenous Metabolite

(-)-Eseroline fumarate

Cat.No: T73930

Cat.No: T83849

Synonym: acetyl-IGKEFKRIVERIKRFLRELVRPLR-amide,P60.4-Ac

Cat. No.	Product Name	Target	Signaling Pathways
T4845	L-Lactic acid 2-HYDROXYPROPIONIC ACID,L-乳酸,L-(+)-Lactic acid,(S)-2-Hydroxypropanoic acid	Endogenous Metabolite; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology
	L-Lactic acid ((S)-2-Hydroxypropanoic acid) 属于天然产物，由丙酮酸的无氧糖酵解产生。L-Lactic acid 是组织缺氧的敏感指标，可作为危重病人的血流动力学指标。
TN6945	Lactic acid 2-hydroxypropanoic acid	Others	Others
	Lactic acid (2-hydroxypropanoic acid) 是糖酵解的产物，广泛存在与自然界中。Lactate acid 在体内收缩骨骼肌缺氧时会产生，可在完全有氧条件下被去除。Lactic acid 可作为危重病人的血流动力学指标。Lactic acid 具有抗肿瘤活性。
T10943	D-(-)-Lactic acid (R)-2-Hydroxypropionic acid,D-乳酸	Others; Endogenous Metabolite	Metabolism; Others
	D-(-)-Lactic acid 是糖发酵（氧化、代谢）中的一种正常中间体。它被鉴定为植物中 ProDH（脯氨酸脱氢酶）的竞争性抑制剂。
T5220	D-(-)-Lactic acid sodium Sodium D-lactate,D-乳酸钠	Others; Endogenous Metabolite	Metabolism; Others
	D-(-)-Lactic acid sodium (Sodium D-lactate) 是一种有机酸。它是一种手性分子，由 L-乳酸和 D-乳酸两种光学异构体组成，其中 L-异构体在生物体中最常见。D-(-)-Lactic acid sodium 也是一种微生物代谢产物。
T3490	alpha-(3,4-Dihydroxyphenyl)lactic acid	Antioxidant	oxidation-reduction
	alpha-(3,4-Dihydroxyphenyl)lactic acid 具有抗氧化活性，可通过 PI3K/Akt/Nrf2 信号通路增强 HO-1 表达以抑制 6-OHDA 诱导的氧化损伤。
T39887	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid (S)-3-(4-羟苯基)乳酸,(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid	Others	Others
	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid ((S)-3-(4-Hydroxyphenyl)lactic acid) 是分离自间肠隐球菌培养基的代谢物，具有高的 DPPH 清除自由基活性和抗氧化活性。
T3604	Sodium dichloroacetate Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯	Apoptosis; Dehydrogenase; Reactive Oxygen Species; PDK	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Sodium dichloroacetate (BCA) 是癌细胞线粒体中的一种代谢调节剂，具有抗癌活性。它抑制丙酮酸脱氢酶激酶，从而导致肿瘤微环境中的乳酸减少。它增加活性氧的产生并促进癌细胞凋亡，还可作为NKCC 抑制剂。
TQ0284	Hydroxyphenyllactic acid	Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology
	Hydroxyphenyllactic acid 是具有抗真菌活性的代谢物。
T5274	D-(+)-Phenyllactic acid D-3-苯乳酸,D-3-Phenyllactic acid	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-(+)-Phenyllactic acid (D-3-Phenyllactic acid) 是一种由白地霉分泌得到的抗菌剂，可抑制部分来自人类和食品的革兰氏阳性菌以及来自人类的革兰氏阴性菌。
T4455	DL-3-Phenyllactic acid DL-3-苯乳酸,3-Phenyllactic acid,2-Hydroxy-3-phenylpropanoic acid	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	DL-3-Phenyllactic acid (3-Phenyllactic acid) 是广谱抗菌化合物，对细菌和真菌具有活性。
TQ0265	Indolelactic acid	Endogenous Metabolite	Metabolism
	Indolelactic acid 是 Azotobacter vinelandii 培养中的色氨酸分解代谢物。
T5809	Stachyose hydrate Stachyose,水苏糖	Others	Others
	Stachyose hydrate 是一种能够增强有益细菌的生长和活性的益生元。它具有降血糖作用，能够调节肠道微生物而改善炎症。
T13509	4-Vinylphenol	Apoptosis; Endogenous Metabolite	Apoptosis; Metabolism
	4-Vinylphenol 是酒中乳酸菌对香豆酸和阿魏酸的代谢产物，在白花蛇舌草中发现。 4-Vinylphenol 在体内诱导细胞凋亡。
T12796	S-Dihydrodaidzein S-二氢大豆苷元,(3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one	Others	Others
	S-Dihydrodaidzein ((3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one) 是一种 dihydrodaidzein 的 (S) 型对映体。其中 dihydrodaidzein 是一种可食用性植物雌激素。
T4S0554	Theaflavine-3,3'-digallate TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素	Others	Others
	Theaflavine-3,3'-digallate (theaflavin digallate) 和乳酸一起可以减少单纯疱疹病毒的传播。
T74862	N-Lactoyl-Phenylalanine N-Lactoylphenylalanine	Endogenous Metabolite	Metabolism
	N-Lactoyl-Phenylalanine (Lac-Phe) 是一种乳酸和苯丙氨酸的肽偶联物，是急性运动中代谢物之一，可用于研究肥胖和代谢相关疾病。
TN1208	2-Amino-3-carboxy-1,4-naphthoquinone	NADPH-oxidase	Immunology/Inflammation
	2-Amino-3-carboxy-1,4-naphthoquinone 是电子转移介质，可改变同型发酵乳酸菌的葡萄糖代谢，可作为双歧杆菌生长刺激剂，它通过NAD(P)H 介导的氧化作用影响双歧杆菌的终产物形态。

天然产物

L-Lactic acid

Cat.No: T4845

Synonym: 2-HYDROXYPROPIONIC ACID,L-乳酸,L-(+)-Lactic acid,(S)-2-Hydroxypropanoic acid

Target: Endogenous Metabolite, Antibacterial, Antibiotic

Cat.No: TN6945

Synonym: 2-hydroxypropanoic acid

Target: Others

D-(-)-Lactic acid

Cat.No: T10943

Synonym: (R)-2-Hydroxypropionic acid,D-乳酸

Target: Others, Endogenous Metabolite

D-(-)-Lactic acid sodium

Cat.No: T5220

Synonym: Sodium D-lactate,D-乳酸钠

Target: Others, Endogenous Metabolite

alpha-(3,4-Dihydroxyphenyl)lactic acid

Cat.No: T3490

Target: Antioxidant

(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

Cat.No: T39887

Synonym: (S)-3-(4-羟苯基)乳酸,(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

Target: Others

Sodium dichloroacetate

Cat.No: T3604

Synonym: Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯

Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK

Hydroxyphenyllactic acid

Cat.No: TQ0284

Target: Endogenous Metabolite, Antifungal

D-(+)-Phenyllactic acid

Cat.No: T5274

Synonym: D-3-苯乳酸,D-3-Phenyllactic acid

Target: Endogenous Metabolite, Antibacterial

DL-3-Phenyllactic acid

Cat.No: T4455

Synonym: DL-3-苯乳酸,3-Phenyllactic acid,2-Hydroxy-3-phenylpropanoic acid

Target: Others, Endogenous Metabolite, Antibacterial

Indolelactic acid

Cat.No: TQ0265

Target: Endogenous Metabolite

Stachyose hydrate

Cat.No: T5809

Synonym: Stachyose,水苏糖

Target: Others

Cat.No: T13509

Target: Apoptosis, Endogenous Metabolite

S-Dihydrodaidzein

Cat.No: T12796

Synonym: S-二氢大豆苷元,(3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

Target: Others

Theaflavine-3,3'-digallate

Cat.No: T4S0554

Synonym: TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素

Target: Others

N-Lactoyl-Phenylalanine

Cat.No: T74862

Synonym: N-Lactoylphenylalanine

Target: Endogenous Metabolite

2-Amino-3-carboxy-1,4-naphthoquinone

Cat.No: TN1208

Target: NADPH-oxidase

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