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63

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T22465 1,2-Distearoyl-sn-glycerol

Others Others
1,2-Distearoyl-sn-glycerol 是一种内标物,可用于分离和鉴定 1,2-diacyl-sn-glycerol (DAG) 的分子种类。
T41046 Biotin-azide

N-(3-Azidopropyl)biotinamide,Biotin-azide

Others Others
Biotin-azide (N-(3-Azidopropyl)biotinamide) 是具有末端叠氮基团的生物素。Biotin-azide 用于通过 Click Chemistry 制备各种生物素化的缀合物。Biotin-azide 参与鉴定新合成的蛋白质。
T19084 1-Naphthyl acetate

AChE Neuroscience
1-Naphthyl acetate 是一种有吸引力的生色底物,用于检测红细胞乙酰胆碱酯酶的活性。它具有检测有机磷农药中毒的潜力。
T0312 Toluidine Blue

氯托洛宁,Blutene chloride

Others Others
Toluidine Blue (Blutene chloride) 是碱性噻嗪异染染料,能够高度亲和酸性组织成分,广泛应用于活体组织的重要染色及特殊染色。
T15598 Isosulfan blue

Others Others
Isosulfan blue 是用于淋巴管造影中淋巴管识别的蓝色染料,可用于乳腺癌前哨淋巴结活检,但其在乳腺癌手术中有发生过敏反应的可能性。
T124698 4-O-p-Coumaroylquinic acid

4-o-Coumaroylquinic acid,4-O-pCoQA

4-O-p-Coumaroylquinic acid (4-O-pCoQA) 是从木瓜皮和果肉中提取的羟基肉桂酸,可作为用于鉴定与玫瑰苹果蚜虫抗性相关的生物标志物。
T10956 Dansyl glutathione

DNS-glutathione

Others Others
Dansyl glutathione is a capture agent used for quantitative assessment and identification of reactive metabolites.
T33568 N-Acetylanonaine

VLT043

N-Acetylanonaine may be used as a substrate for the identification, differentiation, and characterization of aminoacylase(s)/amidohydrolase(s).
T12562 Protein kinase affinity probe 1

Others Others
Protein kinase affinity probe 1 is a protein kinase affinity probe for the functional identification of protein kinases (PKs).
T38361 GSK717

IL Receptor; NOD Immunology/Inflammation; NF-κB
GSK717 是 NOD2(核苷酸结合寡聚结构域 2) 的选择性抑制剂。它抑制壁酰二肽 (MDP) 诱导的 NOD2 介导的信号转导,抑制 MDP 刺激的 HEK293/hNOD2 细胞分泌 IL-8 (IC50为 400 nM)。
T71873 Temechine hydrobromide

Temechine hydrobromide is used for the identification of new diterpenoidal alkaloid leads as tyrosinase inhibitors.
T30307 BCN-E-BCN

BCN-e-BCN is a new cell permeability probe for protein sulfonic acid identification.
T68962 Declenperone

Declenperon acts as a reagent for antimalarial drug lead identification. The are also used in the chemical development of selective and specific serotonin S2-antagonists.
T81488 PHI-27 (rat)

PHI-27 (rat) 为含27个氨基酸的肽类化合物,主要应用于肽激素和其它活性肽的研究识别。
T36128 Tolmetin β-D-Glucuronide

Tolmetin β-D-Glucuronide 与人血清白蛋白具有反应特性,可通过串联质谱法鉴定结合位点和反应机制。
T37424 CAY10781

CAY10781

Others Others
CAY10781 是一种神经纤毛蛋白-1 (NRP-1) 和 VEGF-A.1 之间蛋白质-蛋白质相互作用的抑制剂。当使用浓度为 12.5 μM 时,它可抑制 43% 的相互作用。 当以相同浓度使用时,CAY10781 还抑制 VEGF-A 诱导的儿茶酚胺 A 分化 (CAD) 细胞中 VEGFR2 的磷酸化。
T40616 8-Azido-ATP

8-Azidoadenosine 5'-triphosphate,8-N3-ATP,8-Azido-ATP

8-Azido-ATP is a nucleotide analog that demonstrates photo-reactivity properties. It offers utility in the precise labeling and identification of proteins, particularly those involved in DNA-dependent RNA polymerase activity.
T36224 N-Hippuryl-His-Leu (hydrate)

N-Hippuryl-His-Leu (hydrate) is a synthetic substrate for angiotensin-converting enzyme (ACE) that has been used in the in vitro identification of ACE inhibitors.,
T81489 PHI-27 (porcine)

PHI-27 (porcine)是由27个氨基酸组成的肽类化合物,主要用于探索肽激素及其他活性肽。
T40837 7-Acetoxy-1-methylquinolinium iodide

7-乙酰氧基-1-甲基喹啉溴化物,AMQI

7-Acetoxy-1-methylquinolinium iodide (AMQI) serves as a fluorogenic substrate for cholinesterase, with excitation (Ex) occurring at 320 nm and emission (Em) at 410 nm. In the fluorometric flow system, the hydrolysis of this compound is employed for the detection and identification of inhibitors.
T82006 JM3A

JM3A为高特异性生物活性肽,针对早期肺癌细胞转化过程中新表达的细胞表面波形蛋白(CSV)。通过与荧光团耦合,JM3A能够检测并标记CSV。
T83753 RAD17-derived Peptide TFA

RAD17衍生肽是一种针对共济失调-毛细血管扩张及RAD3相关蛋白/激酶(ATR)的肽类底物。它已被用于识别ATR的抑制剂。
TP1502 MAGE-A3 (195-203)

MAGE-A3 195-203

This peptide MAGE-3-encoded HLA-A24 epitope is a high MHC binder.The identification of this MAGE-3/HLA-A24 peptide may as a result effectiveially offer the opportunities to design peptide-based immunotherapeutic approaches that might prove to be potent in
T78420 3-MeOARh-NTR

3-MeOARh-NTR为一稳定性佳且高选择性的活性成像探针。该化合物对硝基还原酶(NTR)具备极高选择性及信噪比,成为探测内源性硝基还原酶(NTR)的分子工具。
T36743 CDK7/9 tide

CDK7/9 tide is peptide substrate for CDK7 or CDK9[1]. [1]. Robert T, et, al. Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors. Front Chem. 2020 Feb 27; 8:147.
T36031 Desmethyl Ofloxacin (hydrochloride)

Desmethyl ofloxacin is a metabolite of the fluoroquinolone antibiotic ofloxacin .1 1.Sudo, K., Okazaki, O., Tsumura, M., et al.Isolation and identification of metabolites of ofloxacin in rats, dogs and monkeysXenobiotica16(8)725-732(1986)
T83671 CCP-biotin Peptide (non-cyclized)

Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized),Cyclic Citrullinated Peptide-biotin Peptide (non-cyclized)

CCP-biotin Peptide(非环化)是一种生物素化且非环化的圆形瓜氨酸化肽(CCP)版本。该序列对应于人类filaggrin的447-467氨基酸,但包含Q447H、S449C、G459R、E460G和S462C的替换,并在455位的精氨酸处发生了瓜氨酸化。CCP-biotin Peptide(非环化)旨在用于检测可能与线性肽结合的抗瓜氨酸自身抗体。
T70326 Mevidalen HBA

Mevidalen, also known as LY3154207, is a novel, potent, and subtype selective human D1 positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50 = 3 nM). In contrast to orthosteric agonists, LY3154207 showed a distinct pharmacological profile without a bell-shaped dose-response relationship or tachyphylaxis in preclinical models. Identification of a crystalline form of free LY3154207 from the discovery lots was not successful. Instead, a novel cocrystal form with superi...
T77767 GLF16

GLF16 是一种亲水性荧光 SBB 类似物,可有效识别衰老。 它可以使用流式细胞术和活细胞分选来快速检测衰老细胞。 GLF16 适用于各种生物材料中单细胞水平的衰老细胞群的体内鉴定、分离和下游表征。
T81110 SQM-NBD

SQM-NBD 为高效选择性AIE荧光探针,对Cys及Hcy具有卓越的敏感性,其检出限(LOD)分别为54 nM与72 nM。该探针展现出良好的细胞膜穿透能力及低毒性,适用于生理及病理状态下Cys/Hcy的识别。
T80657 SARS-CoV-2 3CLpro-IN-15

Virus Protease Microbiology/Virology
SARS-CoV-2 3CLpro-IN-15(compound a)为β-硝基苯乙烯型抑制剂,专门针对SARS-CoV-2的3CL蛋白酶(3CLpro)而设计。该化合物能有效抑制病毒的复制转录过程,是研发抗COVID-19候选先导化合物的关键因素。
T36132 3β-OH-7-Oxocholenic Acid

3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.2,3 |1. Norii, T., Yamaga, N., and Yamasaki, K. Metabolism of 7β-hydroxycholesterol-4-14C in rat. Steroids 15(3), 303-326 (1970).|2. Alvelius, G., Hjalmarson, O., Griffiths, W.J., et al. Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick dise...
T41171 BODIPY FL VH032

BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of VHL ligands. BODIPY FL VH032 consists of a derivative of von Hippel-Lindau (VHL) ligand VH 032 and a fluorophore BODIPY FL(with excitation peak at 504 nm and emission peak at 520 nm), joined by a polyethylene glycol (PEG) 4 linker. The BODIPY FL VH032 VHL TR-FRET signal is stable...
T75377 Thymolphthalein monophosphate disodium hydrate

Thymolphthalein monophosphate disodium hydrate 是用于测定酸性及碱性磷酸酶显色底物。反应过程中释放的百里酚酞可增加介质pH,促使颜色产生并终止水解作用,特别适合于血清中前列腺磷酸酶的特异性检测。
T38382 8Br-HA

8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 μM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 μM, respectively). 1.Kawaguchi, M., Sekimoto, E., Ohta, Y., et al.Synthesis of fluorescent probes targeting tumor-suppressor protein FHIT and Identification of apoptosis-inducing FHIT inhibitorsJ. Med. Chem.64(13)9567-9576(2021)
T83722 FALGPA TFA

2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine,2-Furanacryloyl-Leu-Gly-Pro-Ala-OH

FALGPA是用于胶原蛋白酶的比色底物。它相对于胰蛋白酶、热蛋白酶和弹性蛋白酶具有选择性。胶原蛋白酶优先结合并切割Leu-Gly (LG) 肽序列以释放呋喃丙烯酰基团,该基团可通过在324至345 nm波长的比色检测被定量,作为衡量胶原蛋白酶活性的手段。FALGPA已被用于识别C. histolyticum胶原蛋白酶的抑制剂。
T83813 8-Azidoadenosine-5'-O-diphosphate sodium

8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate

8-Azidoadenosine-5'-O-diphosphate(8-azido-ADP)是ATP前体和嘌呤受体配体ADP的可点击形式。8-azido-ADP的放射性标记形式已被用作各种蛋白质的光亲和标签,包括从牛脑中分离的谷氨酸脱氢酶(GDH)同工酶,以及从兔网织红细胞中分离的真核翻译起始因子2(eIF2)和鸟苷核苷酸交换因子(GEF)。
T37704 Olanzapine Lactam Impurity

Olanzapine lactam impurity is a potential impurity found in commercial preparations of olanzapine.1It is a degradation product formed by exposure to thermal or oxidative stress. 1.Baertschi, S.W., Brunner, H., Bunnell, C.A., et al.Isolation, identification, and synthesis of two oxidative degradation products of olanzapine (LY170053) in solid oral formulationsJ. Pharm. Sci.97(2)883-892(2008)
T37804 8MDP

Potent equilibrative nucleoside transporter 1 (ENT1) inhibitor (IC50 = 0.43 nM). Inhibits hENT1 and hENT2 uptake of [H3]uridine in K562 cells and K15NTD cells respectively. Lin et al (2011) Design, synthesis, and evaluation of 2-diethanolamino-4,8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanolamino)-6-(N,N-diethanolamino)pyrimido[5,4-d]pyrimidine-fluorescein conjugate (8MDP-fluor), as a novel equilibrativ Bioconjug.Chem. 22 1221 PMID:21539390 |Lin et al (2007) Synthesis, flow cytometric evaluat...
T37779 2,3,4,5-Tetrachlorophenol

2,3,4,5-Tetrachlorophenol is a metabolite of the insecticide γ-lindane.1It is toxic to fathead minnows and rainbow trout (LC50s = 0.496 and 0.304 mg/L, respectively, in tank water).2 1.Chadwick, R.W., and Freal, J.J.The identification of five unreported lindane metabolites recovered from rat urineBull. Environ. Contam. Toxicol.7(2)137-146(1972) 2.Holcombe, G.W., Phipps, G.L., Knuth, L., et al.The acute toxicity of selected substituted phenols, benzenes and benzoic acid esters to fathead minnows ...
T35534 7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine

7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine is a building block.1It has been used in the synthesis of PI3K inhibitors. 1.Scott, W.J., Hentemann, M.F., Rowley, R.B., et al.Discovery and SAR of novel 2,3-dihydroimidazo[1,2-c]quinazoline PI3K inhibitors: Identification of copanlisib (BAY 80-6946)ChemMedChem.11(14)1517-1530(2016)
T37628 Ibuprofen impurity 1

Ibuprofen impurity 1 is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1]. [1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.
T37823 M 084 hydrochloride

TRPC4/5 channel blocker (IC50 values are 3.7-10.3 and 8.2 μM, respectively). Also weakly blocks TRPC3 channels. Exhibits rapid antidepressant and anxiolytic effects in vivo. Zhu et al (2015) Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels. Br.J.Pharmacol. 172 3495 PMID:25816897 |Yang et al (2015) Acute treatment with a novel TRPC4/C5 channel inhibitor produces antidepressant and anxiolytic-like effects in mice. PLoS One 10 e0136...
T37528 tBPC

Positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y4R over Y1R, Y2R and Y5R. Schubert et al (2017) Identification and characterization of the first selective Y4 receptor positive allosteric modulator. J.Med.Chem. 60 7605 PMID:28795803
T37131 MS 15203

Potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of forskolin activated adenylyl cyclase activity in rat hypothalamic memebranes). Exhibits minimal binding to a panel of ~70 GPCRs and 10 other receptors (<22% of radioligand displaced from the target receptors). Increases neuronal activity in the paraventricular nucleus. Increases food intake and body weight in mice. Wardman et al (2016) Identification of a small-molecule ligand that activates the neuropeptide receptor GP...
T35485 6-Prenylindole

6-Prenylindole is a bacterial metabolite that has been found in Streptomyces and has antifungal and antimalarial properties.1 It is active against A. brassicicola strain TP-F0423 and F. oxysporum f. sp. tulipae TU-4-2 (15 and 30 μg/disc in the paper disc assay), and also drug-resistant P. falciparum strain K1 (IC50 = 21 μg/ml).2 |1. Sasaki, T., Igarashi, Y., Ogawa, M., et al. Identification of 6-prenylindole as an antifungal metabolite of Streptomyces sp. TP-A0595 and synthesis and bioactivity o...
T36608 (±)8-HEPE

(±)8-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 8(S)-HEPE and 8(R)-HEPE. The ability of (±)8-HEPE to induce hatching of E. modestus and B. balanoides eggs is probably due to the presence of the 8(R) isomer within the racemic mixture.[1][2] Reference:[1]. Shing, T.K.M., Gibson, K.H., Wiley, J.R., et al. First total synthesis of a barnacle hatching factor 8(R)-hydroxy-eicosa-5(Z),9(E),11(Z)-pentaenoic acid. Tetrahedron Letters 35, 1067-1070 (1994).[2]. Hill, E...
T36409 Roccellic Acid

Roccellic acid is a lichen secondary metabolite that has been found in R. montagnei and has antibacterial and anticancer activities.1,2 It is active against the bacteria S. gordonii and P. gingivalis (MIC = 46.9 μg/ml for both).1 Roccellic acid (100 μg/ml) inhibits proliferation of MDA-MB-231, MCF-7, and DLD-1 cancer cells by 65.3, 75.8, and 87.9%, respectively.2 |1. Sweidan, A., Chollet-Krugler, M., Sauvager, A., et al. Antibacterial activities of natural lichen compounds against Streptococcus ...
T37321 RN-9893 (hydrochloride)

RN-9893 is an antagonist of transient receptor potential vanilloid 4 (TRPV4; IC50s = 0.42 and 0.66 μM, respectively, for the human and rat receptors).1 It is selective for TRPV4 over TRPV1, TRPV3, and TRPM8 (IC50s = 10, >30, and 30 μM, respectively). RN-9893 reduces rat TRPV4 activity induced by 4α-phorbol 12,13-didecanoate or hypotonicity (IC50s = 0.57 and 2.1 μM, respectively, in cell free assays). |1. Wei, Z.L., Nguyen, M.T., O'Mahony, D.J., et al. Identification of orally-bioavailable antago...
T35929 O-Demethyl Apremilast

O-Demethyl apremilast is an active metabolite of the phosphodiesterase 4 (PDE4) inhibitor apremilast .1It inhibits the activity of PDE4 isolated from U937 cells and LPS-induced TNF-α production in isolated human peripheral blood mononuclear cells (PBMCs; IC50s = 8.3 and 5.6 μM, respectively). O-Demethyl apremilast is also an oxidative degradation product of apremilast.2,3 1.Hoffmann, M., Kumar, G., Schafer, P., et al.Disposition, metabolism and mass balance of [14C]apremilast following oral admi...

化合物

1,2-Distearoyl-sn-glycerol
Cat.No: T22465
Synonym:
Target: Others
Biotin-azide
Cat.No: T41046
Synonym: N-(3-Azidopropyl)biotinamide,Biotin-azide
Target: Others
1-Naphthyl acetate
Cat.No: T19084
Synonym:
Target: AChE
Toluidine Blue
Cat.No: T0312
Synonym: 氯托洛宁,Blutene chloride
Target: Others
Isosulfan blue
Cat.No: T15598
Synonym:
Target: Others
4-O-p-Coumaroylquinic acid
Cat.No: T124698
Synonym: 4-o-Coumaroylquinic acid,4-O-pCoQA
Target:
Dansyl glutathione
Cat.No: T10956
Synonym: DNS-glutathione
Target: Others
N-Acetylanonaine
Cat.No: T33568
Synonym: VLT043
Target:
Protein kinase affinity probe 1
Cat.No: T12562
Synonym:
Target: Others
GSK717
Cat.No: T38361
Synonym:
Target: IL Receptor, NOD
Temechine hydrobromide
Cat.No: T71873
Synonym:
Target:
BCN-E-BCN
Cat.No: T30307
Synonym:
Target:
Declenperone
Cat.No: T68962
Synonym:
Target:
PHI-27 (rat)
Cat.No: T81488
Synonym:
Target:
Tolmetin β-D-Glucuronide
Cat.No: T36128
Synonym:
Target:
CAY10781
Cat.No: T37424
Synonym: CAY10781
Target: Others
8-Azido-ATP
Cat.No: T40616
Synonym: 8-Azidoadenosine 5'-triphosphate,8-N3-ATP,8-Azido-ATP
Target:
N-Hippuryl-His-Leu (hydrate)
Cat.No: T36224
Synonym:
Target:
PHI-27 (porcine)
Cat.No: T81489
Synonym:
Target:
7-Acetoxy-1-methylquinolinium iodide
Cat.No: T40837
Synonym: 7-乙酰氧基-1-甲基喹啉溴化物,AMQI
Target:
JM3A
Cat.No: T82006
Synonym:
Target:
RAD17-derived Peptide TFA
Cat.No: T83753
Synonym:
Target:
MAGE-A3 (195-203)
Cat.No: TP1502
Synonym: MAGE-A3 195-203
Target:
3-MeOARh-NTR
Cat.No: T78420
Synonym:
Target:
CDK7/9 tide
Cat.No: T36743
Synonym:
Target:
Desmethyl Ofloxacin (hydrochloride)
Cat.No: T36031
Synonym:
Target:
CCP-biotin Peptide (non-cyclized)
Cat.No: T83671
Synonym: Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized),Cyclic Citrullinated Peptide-biotin Peptide (non-cyclized)
Target:
Mevidalen HBA
Cat.No: T70326
Synonym:
Target:
GLF16
Cat.No: T77767
Synonym:
Target:
SQM-NBD
Cat.No: T81110
Synonym:
Target:
SARS-CoV-2 3CLpro-IN-15
Cat.No: T80657
Synonym:
Target: Virus Protease
3β-OH-7-Oxocholenic Acid
Cat.No: T36132
Synonym:
Target:
BODIPY FL VH032
Cat.No: T41171
Synonym:
Target:
Thymolphthalein monophosphate disodium hydrate
Cat.No: T75377
Synonym:
Target:
8Br-HA
Cat.No: T38382
Synonym:
Target:
FALGPA TFA
Cat.No: T83722
Synonym: 2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine,2-Furanacryloyl-Leu-Gly-Pro-Ala-OH
Target:
8-Azidoadenosine-5'-O-diphosphate sodium
Cat.No: T83813
Synonym: 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate
Target:
Olanzapine Lactam Impurity
Cat.No: T37704
Synonym:
Target:
8MDP
Cat.No: T37804
Synonym:
Target:
2,3,4,5-Tetrachlorophenol
Cat.No: T37779
Synonym:
Target:
7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine
Cat.No: T35534
Synonym:
Target:
Ibuprofen impurity 1
Cat.No: T37628
Synonym:
Target:
M 084 hydrochloride
Cat.No: T37823
Synonym:
Target:
tBPC
Cat.No: T37528
Synonym:
Target:
MS 15203
Cat.No: T37131
Synonym:
Target:
6-Prenylindole
Cat.No: T35485
Synonym:
Target:
(±)8-HEPE
Cat.No: T36608
Synonym:
Target:
Roccellic Acid
Cat.No: T36409
Synonym:
Target:
RN-9893 (hydrochloride)
Cat.No: T37321
Synonym:
Target:
O-Demethyl Apremilast
Cat.No: T35929
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3O2709 Bronze Red

808猩红,Scarlet 808

Others Others
Bronze Red 属于酰胺类有机物,可用于含量测定、鉴定、药理实验等。
T2S0712 Sinigrin

黑芥子苷,Allylglucosinolate,2-Propenylglucosinolate

Others Others
Sinigrin (2-Propenylglucosinolate) 是十字花科植物中主要的硫代葡萄糖苷,具有抗脂肪生成作用。它在芥子油苷的分离和鉴定程序中用作参考材料。
TN2254 Taccalonolide A

根薯酮内酯A,根薯酮内酯 A

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Taccalonolide A 是从水田七根茎中分离得到的一种类固醇,具有细胞毒性和抗疟活性。它在体外对过表达 p 糖蛋白、多药耐药蛋白 7 细胞系有抑制作用,抑制 SK-OV-3 细胞生长的 IC50值为 622 nM。它是微管稳定剂,能引起 G2-M 期滞留、Bcl-2 磷酸化,并引发细胞凋亡。
T11555 Heptasaccharide Glc4Xyl3

Others Others
Heptasaccharide Glc4Xyl3 is a covalent inhibitor of endo-xyloglucanases. It used for the identification and analysis of diverse xyloglucan-active enzymes in nature.
T37690 Phenylpyropene A

Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3 |1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of ...
T35415 α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabol...

天然产物

Bronze Red
Cat.No: T3O2709
Synonym: 808猩红,Scarlet 808
Target: Others
Sinigrin
Cat.No: T2S0712
Synonym: 黑芥子苷,Allylglucosinolate,2-Propenylglucosinolate
Target: Others
Taccalonolide A
Cat.No: TN2254
Synonym: 根薯酮内酯A,根薯酮内酯 A
Target: Apoptosis, Microtubule Associated
Heptasaccharide Glc4Xyl3
Cat.No: T11555
Synonym:
Target: Others
Phenylpyropene A
Cat.No: T37690
Synonym:
Target:
α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
Cat.No: T35415
Synonym:
Target:
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