68
17
Cat. No. | Product Name | Target | Signaling Pathways |
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T31838 |
Folic acid, methyl-
x-Methylfolic acid,x-Methyl folic acid,x-Methylpteroylglutamic acid |
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Folic acid, methyl- is a nutrient that belongs to the vitamin B family. Folate is significant for the easy conversion of carbohydrates into glucose and is essential in red blood cell formation, cell division, detoxification, and the production of some neu | |||
T32075 |
HH-Folic acid
|
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HH-Folic acid derives from vitamin B9. | |||
T31756 |
Fe-Cap folic
|
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Fe-Cap folic is an encapsulated dosage for use as an iron supplement in pregnancy. | |||
T25999 |
Pteropterin
Teropterin,PTGA,Pteroyl triglutamic acid,Folic acid diglutamate |
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Pteropterin is an antineoplastic agent. | |||
T0699 |
Sulfamonomethoxine
磺胺间甲氧嘧啶,磺胺间甲氧嘧啶钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Sulfamonomethoxine 是一种磺胺类抗菌剂。它可研究血液动力学,竞争性抑制剂二氢叶酸合成,从而阻断叶酸合成。 | |||
T0849 |
Pyrimethamine
Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶 |
DHFR; Antifolate; Parasite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology |
Pyrimethamine (Pirimecidan) 是一种二氢叶酸还原酶的竞争性抑制剂,用作抗疟药。 | |||
T24962 |
10-Formylfolic acid
|
DHFR | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
10-Formylfolic acid 是一种新型有效的二氢叶酸还原酶 (dihydrofolate reductase) 抑制剂,可用于研究白血病。 | |||
T33691 |
Nitrosofolic acid
CCRIS 466,N-Nitrosofolic acid,Glutamic acid, N-nitroso-N-pteroyl-, L- |
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Nitrosofolic acid is a folic acid derivaive. | |||
T32100 |
Homofolic acid
NSC-79249,NSC 79249,9-Methylfolic acid,NSC79249,Homofolate |
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Homofolic acid is a folic acid analog. | |||
T35413 |
(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)
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(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism. Its metabolites participate in the synthesis of thymidine for incorporation into DNA or the synthesis of purines, as well as in the formation of methionine, which can be converted to the ubiquitous methyl donor, S-adenosylmethionine . THFA has also been used to study the activation of metabolite-binding ribos... | |||
T25332 |
Dihydrohomofolic acid
|
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Dihydrohomofolic acid is a substrate for dihydrofolate reductase that produces tetrahydro-homo folate which in turn suppresses thymidylate synthetase and then DNA synthesis. | |||
T24983 |
5-Deazaisofolic acid
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5-Deazaisofolic acid shows potent antitumor activity. | |||
T33035 | Lyofolic acid | ||
Lyofolic acid is a bioactive chemical. | |||
T24967 | 11-Oxahomofolic acid | ||
11-Oxahomofolic acid is a potential antitumor drug. | |||
T73731 |
10-Formyltetrahydrofolic acid disodium
|
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10-Formyltetrahydrofolic acid disodium 为四氢叶酸衍生物,作为甲酰基供体参与合成代谢。该化合物作为甲酰基转移酶反应底物,涉及嘌呤生物合成过程。 | |||
T24981 |
5,6,7,8-Tetrahydro-8-deazahomofolic acid
5,6,7,8-Tdfa |
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5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor. | |||
T26261 |
Tetrahydrohomofolic acid
Tetrahydrohomofolate,Homofolic acid, tetrahydro-,H4HF,THHF |
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Tetrahydrohomofolic acid is a thymidylate synthetase inhibitor, antibacterial, and antimalarial agent. | |||
T24991 |
8-Deazahomofolic acid
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8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor. | |||
T24964 |
10-Thiofolic acid
NSC238147,NSC-238147,NSC 238147 |
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10-Thiofolic acid is a potential antibacterial, antineoplastic. | |||
T24990 |
8-Deazafolic acid
NSC-173522,NSC173522,NSC 173522 |
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8-Deazafolic acid is a potent folate-dependent bacteria inhibitor, Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 7469), and to have activity against lymphoid leukemia L1210 in mice. | |||
T26007 |
Pyrrofolic acid
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Pyrrofolic acid shows high anti-folate biological activity for S. faecalis. | |||
T24965 |
11-Deazahomofolic acid
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11-Deazahomofolic acid is a phosphoribosylglycinamide formyltransferase inhibitor. | |||
T26544 |
Acanthifolicin
Acanthifolic acid |
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Acanthifolicin, an okadaic acid derivative, has been shown top inhibit protein phosphatase 1 with an IC50= 20 nM (similar to that of okadaic acid at 19 nM). | |||
T62996 | 10-Formyl-5,8-dideazafolic acid | ||
10-Formyl-5,8-dideazafolic acid 是一种胸苷酸合成酶 (thymidylate synthase) 抑制剂。 | |||
T24979 | 5,10-Dideazafolic acid | ||
5,10-Dideazafolic acid is an antileukemic drug. | |||
T16045 |
Methotrexate metabolite
DAMPA,甲喋呤杂质E |
Antifolate; Drug Metabolite | Cell Cycle/Checkpoint; Metabolism |
Methotrexate metabolite (DAMPA) (DAMPA)是 Methotrexate 的活性代谢物。Methotrexate 具有拮抗叶酸 (folic acid) 的作用,被用作免疫抑制剂。 | |||
T20339 |
7-Hydroxymethotrexate
NSC 380963,NSC-380963,NSC380962,NSC380963,NSC 380962,NSC-380962 |
Drug Metabolite | Metabolism |
7-Hydroxymethotrexate 是 Methotrexate 主要的代谢产物。Methotrexate 对叶酸具有抑制作用,抑制二氢叶酸还原酶,从而防止叶酸转化为四氢叶酸,并抑制 DNA 合成。Methotrexate 对代谢也具有抑制作用。 | |||
T20882 |
4-Nitrobenzoic acid
Kyselina p-nitrobenzoova,4Nitrobenzoic acid,Nitrodracylic acid,4 Nitrobenzoic acid |
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4-Nitrobenzoic acid (4Nitrobenzoic acid) 是一种药物中间体,常在叶酸、DABA、PABA 和染料的生产中出现。 | |||
T7593 |
Levomefolate calcium
左旋甲状腺素钙,L-5-甲基四氢叶酸钙 |
Antifolate | Cell Cycle/Checkpoint |
Levomefolate calcium 是一种人工形式的叶酸。它是叶酸的一种辅酶形式,是膳食补充剂中生物利用度更高的替代品。 | |||
T0930 |
Sulfadiazine
Sulphadiazine,磺胺嘧啶 |
Antibacterial; Antibiotic; Parasite; Autophagy | Autophagy; Microbiology/Virology |
Sulfadiazine (Sulphadiazine) 是一种磺胺类抗生素具有抗疟活性,可研究弓形虫病。 | |||
T21434 |
Sulfacetamide
NSC 63871,磺胺醋酰,NSC-63871,Sebizon,Region,NSC63871,Sulphacetamide,Acetosulfamine |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Sulfacetamide (NSC-63871) 是一种抗生素,通过限制细菌生存所需的叶酸的存在来治疗睑缘炎或结膜炎,有潜力用于眼部感染的研究。 | |||
T68629 |
Lysine-iodoacetylmethotrexate
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Lysine-iodoacetylmethotrexate if a Folic Acid Antagonist. | |||
T31508 |
Diopterin
Folate monoglutamate,Pteroyl diglutamic acid |
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Diopterin is a folic acid analog. | |||
T34183 |
Pteroylpentaglutamic acid
Pte-penta-glu,NSC372667,NSC 372667,NSC-372667 |
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Pteroylpentaglutamic acid within the folic acid family is a bioactive chemical. | |||
T11144 |
EC0488
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Others | Others |
EC0488 was used to synthesize EC0531, which has folic acid receptor specificity and anti-tumor activity. | |||
T34822 |
Tetrahydromethotrexate
NSC 526044,NSC-526044,NSC526044 |
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Tetrahydromethotrexate is a folic acid derivative. | |||
T30690 |
Calcium dextrofolinate
Calcium (6R)-folinate |
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Calcium dextrofolinate is a calcium salt of a derivative of Folic Acid. | |||
T29461 |
5-Methyltetrahydrofolate triglutamate
5-Me-Thf(glu)3 |
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5-Methyltetrahydrofolate triglutamate is a form of folic acid. | |||
T25796 |
Methotrexate 1-methyl ester
Methotrexate related compound I,Methotrexate alpha-methyl ester |
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Methotrexate 1-methyl ester is an impurity of Methotrexate which is a folic acid antagonist. It's used as an antineoplastic and antirheumatic. | |||
T24961 |
10-Deazaaminopterin
NSC 311469,NSC-311469,10-Deaza-aminopterin,NSC311469 |
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10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor. | |||
T70080 |
Methasquin
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Methasquin is a folic acid antagonist that has been used in the treatment of experimental leukemia; acts by inhibiting the dihydrofolate reductase in the cell. | |||
T24976 | 3'-Fluoroaminopterin | ||
3'-Fluoroaminopterin is a folic acid antagonist agent. | |||
T24972 |
2'-Fluoroaminopterin
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2'-Fluoroaminopterin is a folic acid antagonist agent. | |||
T29434 |
4-Desacetylvinblastine hydrazide
DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide |
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Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent. | |||
T31851 |
Formiminoglutamic acid
NSC-334078,NSC334078,NSC 334078 |
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Formiminoglutamic acid is used to indicate folic acid deficiency and megaloblastic anemia of pregnancy with the measurement in the urine after oral administration of histidine. | |||
T32706 |
Levomefolate calcium pentahydrate
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Levomefolate calcium pentahydrate is the calcium salt of 5-methyltetrahydrofolic acid, a biologically active form of folic acid that functions, in conjunction with Vitamin B12. Levomefolate is included in formulations of certain oral contraceptives to ens | |||
T24535 |
Ninopterin
NSC-107137,NSC107137,9-Me-PGA,NSC 107137,L-Glutamic acid, 9-methylpteroyl- |
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Ninopterin is an experimental antineoplastic and folic acid analog. | |||
T25208 |
CB 3717
CB3717,CB-3717,N(sup 10)-Propargyl-5,8-dideazafolic acid |
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CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist. | |||
T25358 |
EC-17 free acid
EC17,EC 17,EC-17,FTIC-Folate,Folate-FTIC |
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EC17 is a FITC conjugated folic acid, also known as Folate-FITC. It also acts as an FRα-targeting agent that fluoresces at 500nm. EC17 is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic acti | |||
T25797 |
Methotrexate 5-methyl ester
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Methotrexate 5-methyl ester is an impurity of Methotrexate which is a folic acid antagonist. It's used as an antineoplastic and antirheumatic. |
Cat. No. | Product Name | Target | Signaling Pathways |
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T0062 |
Folic acid
Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Folic acid (Vitamin B9) 是维生素B9,是合成DNA/RNA,新细胞产生和维持的必要成分。 | |||
T31836 |
Folate sodium
Folic acid, monosodium salt,Folvite sodium |
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Folate sodium, as a member of the vitamin B family, can stimulate the hematopoietic system. Folic acid can be used in the treatment and prevention of folate deficiencies and megaloblastic anemia. | |||
T7730 |
Aminopterin
APGA,氨基蝶呤,4-Aminofolic acid |
Antifolate | Cell Cycle/Checkpoint |
Aminopterin (4-Aminofolic acid) 是叶酸的 4-氨基衍生物,是叶酸拮抗剂,具有抗癌和免疫抑制活性,用于研究儿童白血病。它催化叶酸还原为四氢叶酸,竞争性抑制二氢叶酸还原酶,Ki 值为 3.7 pM。 | |||
T7094 |
Levomefolic Acid
L-5-甲基四氢叶酸,5-MTHF,5-甲基四氢叶酸 |
Reactive Oxygen Species; Endogenous Metabolite | Immunology/Inflammation; Metabolism; NF-κB |
Levomefolic Acid (5-MTHF) 是一种具有口服活性、可穿过血脑屏障的天然活性叶酸,是广泛使用的叶酸食品补充剂。 | |||
T13516 |
5-Methyltetrahydrofolic acid
甲基叶酸盐,5-Methyl THF |
Endogenous Metabolite | Metabolism |
5-Methyltetrahydrofolic acid (5-Methyl THF) 是四氢叶酸的甲基化衍生物,具有生物活性。5-Methyltetrahydrofolic acid 是主要的天然膳食叶酸,是血浆和脑脊液中叶酸的主要形式。 | |||
T21367 |
Tetrahydrofolic acid
5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate |
Endogenous Metabolite | Metabolism |
Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) 是一种维生素 B9 衍生物,是生物体常见的一碳供体,参与生物体生长代谢。 | |||
T15128 |
Dihydrofolic acid
7,8-Dihydrofolic acid,Dihydrofolate |
Others | Others |
Dihydrofolic acid (7,8-Dihydrofolic acid) 是一种叶酸衍生物,在二氢叶酸还原酶的作用下生成四氢叶酸。 | |||
TN3058 |
4-O-Methylgrifolic acid
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Others | Others |
4-O-Methylgrifolic acid is a natural carbonic anhydrase Ⅱ(CAⅡ) inhibitor, it shows in-hibitory activities against CAⅡ with IC50s in the range of 6.37-71.73 umol/L. | |||
TN4167 |
Grifolic acid
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Antifection | Microbiology/Virology |
Grifolic acid is a natural carbonic anhydrase Ⅱ inhibitor(CAⅡ), it shows in-hibitory activities against CAⅡ with IC50 of 6.37 umol/L. Grifolic acid has antibacterial activity, it can inhibit the growth of Staphylococcus aureus and Staphylococcus epidermid | |||
TN5938 |
Rubifolic acid
30-Hydroxyursolic acid |
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Rubifolic acid是一种天然产物,属于茜草科拉拉藤属,其产品编号为 TN5938,CAS号为 80489-65-2。Rubifolic acid可用作对照参考。 | |||
T0148 |
Folinic acid calcium
亚叶酸钙,Wellcovorin,Calcium folinate,Leucovorin Calcium,Folinic acid calcium salt |
DNA/RNA Synthesis; Endogenous Metabolite; Antifolate | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Folinic acid calcium (Leucovorin Calcium) 是叶酸的活性代谢物,是一种解毒剂,通常与甲氨蝶呤 (MTX) 联用,以降低 MTX 诱导的毒性。 | |||
T8854 |
PTEROIC ACID
|
Others | Others |
PTEROIC ACID 是叶酸结构的一部分 | |||
T1040 |
Vitamin B12
Cyanocobalamin,Cobalamin,维生素B12 |
Endogenous Metabolite | Metabolism |
Vitamin B12 (Cobalamin) 是一种维生素,在维持血流形成和脑、神经系统正常功能等方面发挥关键作用。 | |||
TN6988 |
Pterine-6-carboxylic acid
6-Carboxypterin |
DNA; PDE | DNA Damage/DNA Repair; Metabolism |
Pterine-6-carboxylic acid (6-Carboxypterin) 是叶酸的光降解产物,可被用作光敏感剂研究UVA 破环DNA 结构的分子机制。 | |||
T13969 |
Xanthopterin (hydrate)
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Others; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
Xanthopterin hydrate 是东方大黄蜂翅膀中黄色颗粒的主要成分,是一种非共轭的蝶啶天然产物,在 386/456 nm 处产生特征性的激发光。 它可抑制 RNA 合成,引起大鼠肾脏生长和肥大。 | |||
T4877 |
L-Homocystine
|
Endogenous Metabolite | Metabolism |
L-Homocystine 是一种 L-homocysteine 的氧化物。其中 L-homocysteine 是抗血栓因子、血管舒张损害剂、促炎因子,也是研究心血管疾病发生机制的内质网应激反应的诱导剂。 | |||
T29477 |
6R-Leucovorin
(6R,2'S)-Folinic acid,Dextrofolinic acid |
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6R-Leucovorin is a derivative of Folic Acid. |