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44

抑制剂 & 化合物

22

天然产物

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Cat. No. Product Name Target Signaling Pathways
T8425 Linoleoyl Ethanolamide

TRP/TRPV Channel Membrane transporter/Ion channel
Linoleoyl ethanolamide 是脂肪酸乙醇酰胺。它可弱结合 CB1 和 CB2 受体,并分别抑制[3H]CP-55,940的结合,Ki 分别为 10 和 25μM。它在引起小鼠过氧化氢酶方面的效力是 anandamide 的4倍,且对睡眠时间无延长效果。
T7115 Pymetrozine

CGA 215944,吡蚜酮

Antibacterial Microbiology/Virology
Pymetrozine (CGA 215944)是一种针对Homoptera的喂养抑制剂,能有效防止通过蚜虫Myzus persicae传播cauliflower mosaic caulimovirus。
T38470 Obestatin (human)

Obestatin (human) 是一种由 preproghrelin 经过剪切形成的G蛋白欧联实体39的内源性配体,可以剂量依赖的方式抑制进食,可用于研究肥胖。
T20713 Flonicamid

UNII-9500W2Z53J,N-(cyanomethyl)-4-(trifluoromethyl)nicotinamide

Others Others
Flonicamid (N-(cyanomethyl)-4-(trifluoromethyl)nicotinamide) 是一种吡啶甲酰胺杀虫剂,在食用日本萝卜叶的过程中抑制蚜虫(M.persicae)的唾液分泌和汁液摄入。它对棉蚜、红蚜、巴迪蚜、禾谷蚜和大鼠产生毒性。
TP1889 MCL0020

MCL 0020

Melanocortin Receptor GPCR/G Protein; Neuroscience
MCL0020 是一种有效的选择性黑素皮质素MC4受体拮抗剂,IC50为 11.63 nM。它剂量依赖性减轻束缚应激诱发的厌食症,在体内表现出抗焦虑样活性。
T19940 Sulfoxaflor

GF 2372,氟啶虫胺腈,GF 2032,XDE 208

AChR Neuroscience
Sulfoxaflor (GF 2032) 是 nAChR1 和 nAChR2 亚型的激动剂,是一种作用于昆虫中枢神经系统的内吸性杀虫剂。 Sulfoxaflor 用于防治吸食汁液的昆虫,如褐飞虱、烟粉虱、桃蚜和棉蚜。
TP1981L Neuropeptide S (Mouse) acetate

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Neuropeptide S (Mouse) acetate 是一种生物活性肽。它作为 20 种氨基酸的神经递质/神经调节剂,可用于觉醒、焦虑、运动、摄食行为、记忆和药物成瘾的研究。
T26538 AC-24,055

AC24,055,AC 24,055,AC-24055,AC24055,AC 24055

AC-24,055 is a synthetic insect feeding repellent.
T32246 J-115814

J 115814J-115814, (+/-)-,UNII-81DP93CF8M

J-115814 is a potent feeding stimulant.
T29938 AM-3102

KDS-5104,AM 3102,Methyl oleoylethanolamide

AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding r
T26800 BIBO3304

BIBO-3304,BIBO 3304

BIBO3304 is a selective NPY Y1 receptor antagonist (IC50 values are 0.38 and 0.72 nM at human and rat receptors respectively). BIBO3304 inhibits NPY- and fasting-induced feeding in vivo following central administration.
TP2407 Small cardioactive peptide A

SCPA

Small cardioactive peptide A, as a neuropeptide that modulates neuromuscular synapsis in Aplysia, can also function as a neural cotransmitter in molluscs and exert a role in both the central and peripheral modulation of the control of feeding behavior.
T68565 ANN33840

ANN33840 is a novel selective 5-HT2C agonist with >300-fold functional selectivity over 5-HT2B and >70-fold functional selectivity over 5-HT2A, reducing food intake in an acute rat feeding model.
T20590 Zilpaterol hydrochloride

Zilpaterol hydrochloride is a agonist of β-adrenergic receptor (AR). It is used to increase the feeding efficiency and the size of cattle.
T38813 6-Azathymine acid

6-Azathymine acid is a metabolite derived from Pymetrozine, a potent insecticide known for its effectiveness against plant-sucking insects, specifically aphids and whiteflies. Pymetrozine's neuroactivity disrupts the feeding behavior of these pests, making it a valuable tool in protecting various crops, including vegetables, cotton, field crops, and fruits.
T80146 Galanin-Like Peptide (rat)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Galanin-Like Peptide (rat) 是含60个氨基酸的神经肽,主要功能是调节摄食、体重及能量代谢。
TP1976 Oxyntomodulin

胃泌酸调节素,Oxyntomodulin (porcine, bovine)

GLP-1 receptor agonist. Endogenous preproglucagon-derived neuropeptide that modulates feeding and metabolism. Also secreted by intestinal L-cells. Increases cAMP production and inhibits gastric acid secretion in rat stomach. Also weak glucagon receptor ag
TP1550 Orexin A (human, rat, mouse) (TFA)

Endogenous agonist at orexin receptors (Ki values are 20 and 38 nM for OX1 and OX2 receptors respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions.
T39823 Apelin-12

Apelin-12 is a highly potent C-terminal fragment of a polypeptide that exhibits a strong affinity towards the orphan receptor APJ. It plays a role in maintaining body fluid balance and regulating feeding control in the central nervous system. Additionally, Apelin-12 functions as an inhibitor of HIV-1 entry through the APJ receptor and demonstrates neuroprotective properties.
T70938 SN00799639

SN00799639, also known as SN639, is a potent inhibitor of the motility and development of parasitic larvae of Haemonchus contortus, a blood-feeding parasitic nematode of major economic importance in ruminants. SN639 displayed lower potency, with IC50 values of 8.4 μM (xL3 motility) and 0.29 μM (L4 development).
TP1529 Galanin (1-19), human

Galanin (1-19), human, represents the fragment encompassing amino acids 1 to 19 of the human galanin neuropeptide. Galanin (GAL) is known for its extensive distribution and multifaceted biological roles, such as regulating hormone secretion, providing antinociceptive effects, and altering feeding behavior.
T80144 Galanin-Like Peptide (human)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Galanin-Like Peptide (human) 是由60个氨基酸组成的神经肽,在调节摄食、体重和能量代谢方面具有重要功能。
TP2020 [Pro3]-GIP (Mouse)

GIP receptor antagonist (IC50 = 2.6μM). Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insul
T76355 Neuropeptide Y (3-36) (porcine)

Neuropeptide Y (3-36) (porcine) 是一种针对 Y2 亚型的 NPY 受体的激动剂,同时也通过一种尚未明确的受体来调控大鼠的摄食行为。
TP2093 Apelin-36(human)

Apelin-36 (human)

Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Bloc
T21811 LH 21

LH-21 是一种有效的体内中性大麻素 CB1受体拮抗剂。LH-21 会导致剂量依赖性进食抑制,减少肥胖 Zucker 大鼠的食物摄入和体重增加。
TP2094 Apelin-36(rat, mouse)

Apelin-36 (rat, mouse)

Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM). Involved in regulation of cardiovascular function, fluid homeostasis
TP1542 26Rfa, Hypothalamic Peptide, human

This human neuropeptide of the RFamide peptide family with orexigenic activity may be also involved in the control of feeding behavior. The 26RFa gene is exclusively expressed in the ventromedial hypothalamic nucleus and in the lateral hypothalamic area.
T26860 BMS-814580

BMS-814580 is a potent and selective functional antagonist (Kb = 117 nM) of human MCHR1. BMS-814580 exhibits potent binding affinity (Ki = 17 nM) for human MCHR1. BMS-814580 also exhibits potent binding affinities for cynomolgus monkey and rat MCHR1 (Ki o
TP1885 [(pF)Phe4]Nociceptin(1-13)NH2

Highly potent and selective nociceptin/orphanin FQ receptor (OP4) agonist peptide (pKi = 10.68; pEC50 = 9.80). Displays > 8000-fold selectivity over δ, κ, and μ opioid receptors and has relatively long lasting pronociceptive, hypotensive, negative inotrop
T76365 CART (1-39), Human, Rat

CART (1-39), Human, Rat, 是一种由其1至39个残基构成的神经肽, 具有明显的减少食欲作用, 被认为是鼠类的饱腹因子, 并与瘦素及神经肽Y有着紧密的联系。它能有效抑制正常及饥饿状态下的摄食行为, 同时也能引发焦虑与压力相关的反应。
T75853 HS014 TFA

HS014 TFA 是一种高效、选择性的黑素皮质素-4(MC4)受体拮抗剂,对人 MC4、MC1、MC3 和 MC5 受体的Ki 值分别为 3.16、108、54.4 和 694 nM。HS014 TFA 增加自由喂养大鼠的食物摄取量。
T81491 Pheromonotropin (pseudaletia separata)

Pss-PT

Pheromonotropin (Pseudaletia separata) (Pss-PT),是粘虫信息素,含有C端五肽FXPRL-酰胺。该化合物隶属于PK/PBAN家族,能够促进飞蛾性信息素的生物合成,并介导其摄食行为(肠道肌肉收缩)、发育过程(胚胎滞育、蛹滞育及蛹化)以及抵御天敌昆虫。
T73081 (S)-V-0219

(S)-V-0219 是 V-0219 的对映异构体。V-0219 是一种口服有效的 GLP 受体 (GLP Receptor,GLP-1R) 的正变构调节剂 (PAM)。(S)-V-0219 可激活表达 hGLP-1R 的 HEK 细胞中的钙流。(S)-V-0219 具有口服活性,可改善小鼠体内的高葡萄糖水平,并抑制禁食小鼠的进食行为。
TP2049 CRSP-1

Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related peptide (CGRP) and adrenomedullin recept
T36099 Jacaric Acid

Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants. Structurally, it is an 18-carbon ω-6 triene isomer of γ-linolenic acid . Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 μM). It increases the production of reactive oxygen species, and cytotoxicity is abolished by the antioxidant α-tocopherol, suggesting that apoptosis results from oxidative stress. Jacaric acid is metabolized in vivo to conju...
T74265 (S)-V-0219 hydrochloride

(S)-V-0219 hydrochloride 是 V-0219 的对映异构体。V-0219 是一种口服有效的 GLP 受体 (GLP Receptor,GLP-1R) 的正变构调节剂 (PAM)。(S)-V-0219 hydrochloride 可激活表达 hGLP-1R 的 HEK 细胞中的钙流。(S)-V-0219 hydrochloride 具有口服活性,可改善小鼠体内的高葡萄糖水平,并抑制禁食小鼠的进食行为。
T68219 Peraclopone

Peraclopone is a hypolidemic drug. It is an inhibitor of 7-Dehydrocholesterol reductase. Peraclopone potently inhibits the final step in cholesterol biosynthesis. Feeding this agent to rats leads to a rapid replacement of membrane cholesterol with its immediate precursor 7-dehydrocholesterol, and a dramatic reduction in plasma sterol concentration. Peraclopone caused a dose-dependent decrease in cholesterol and a concomitant accumulation of provitamin D3 (7-dehydrocholesterol) in the skin, which...
TP2049L CRSP-1 acetate(697327-12-1 Free base)

CRSP-1 acetate(697327-12-1 Free base) 是一种内源性中枢降钙素(CT)受体激动剂,其刺激cAMP形成的效力是CT的350倍(ED50值分别为0.2和71nM)。CRSP-1 acetate 对降钙素基因相关肽 (CGRP) 和肾上腺髓质素受体没有活性。CRSP-1 acetate 抑制多核破骨细胞的形成,其体外功效与CT相似。CRSP-1 acetate 抑制自由进食大鼠的食物摄入并升高体温,并显着降低体内血浆钙水平。
T35598 Neuromedin U-25 (human) (trifluoroacetate salt)

Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction.1Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-mediated rolesin vivo, as it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock.2,2NMU-25 is the active form of NMU in humans. It binds with high affinity to receptors on human left ventricle and coronary artery ...
T36590 9-PAHSA

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxylated C-16 or C-18 lipid. 9-PAHSA is a FAHFA in which palmitic acid is esterified to 9-hydroxy stearic acid. PAHSAs are the most abundant forms of FAHFA in serum as well as whi...
T36586 12-PAHSA

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 12-PAHSA is a FAHFA in which palmitic acid is esterified at the 12th carbon of hydroxy stearic acid. Among the FAHFA family members, PAHSAs ar...
T37809 Alphitonin

Alphitonin is a flavonoid that has been found in L. leptolepis wood.1 It is also a metabolic intermediate that is formed during the catabolism of quercetin by the human gut bacteria E. ramulus.2,3 |1. Chen, K., Ohmura, W., Doi, S., et al. Termite feeding deterrent from Japanese larch wood. Bioresour. Technol. 95(2), 129-134 (2004).|2. Braune, A., Gütschow, M., Engst, W., et al. Degradation of quercetin and luteolin by Eubacterium ramulus. Appl. Environ. Microbiol. 67(12), 5558-55567 (2001).|3. J...
T37718 Galanin (rat, mouse) (trifluoroacetate salt)

GAL (rat, mouse),Galanin (rat, mouse) (trifluoroacetate salt)

Galanin is a neuropeptide with diverse biological activities. [1][2][3][4][5] It binds to rat galanin (GAL) receptor subtypes GAL1-3 (IC50s = 0.339, 1.35, and 3.31 nM, respectively) and human GAL1-3 (IC50s = 0.288, 1.62, and 12.3 nM, respectively). [1] Galanin binds to and inhibits contraction of guinea pig gastric smooth muscle cells induced by carbachol . [2] In vivo, Galanin (6 nmol, i.c.v.) increases feeding behavior in rats and increases latency to hindpaw withdrawal in response to heat and...

化合物

Linoleoyl Ethanolamide
Cat.No: T8425
Synonym:
Target: TRP/TRPV Channel
Pymetrozine
Cat.No: T7115
Synonym: CGA 215944,吡蚜酮
Target: Antibacterial
Obestatin (human)
Cat.No: T38470
Synonym:
Target:
Flonicamid
Cat.No: T20713
Synonym: UNII-9500W2Z53J,N-(cyanomethyl)-4-(trifluoromethyl)nicotinamide
Target: Others
MCL0020
Cat.No: TP1889
Synonym: MCL 0020
Target: Melanocortin Receptor
Sulfoxaflor
Cat.No: T19940
Synonym: GF 2372,氟啶虫胺腈,GF 2032,XDE 208
Target: AChR
Neuropeptide S (Mouse) acetate
Cat.No: TP1981L
Synonym:
Target: Neuropeptide Y Receptor
AC-24,055
Cat.No: T26538
Synonym: AC24,055,AC 24,055,AC-24055,AC24055,AC 24055
Target:
J-115814
Cat.No: T32246
Synonym: J 115814J-115814, (+/-)-,UNII-81DP93CF8M
Target:
AM-3102
Cat.No: T29938
Synonym: KDS-5104,AM 3102,Methyl oleoylethanolamide
Target:
BIBO3304
Cat.No: T26800
Synonym: BIBO-3304,BIBO 3304
Target:
Small cardioactive peptide A
Cat.No: TP2407
Synonym: SCPA
Target:
ANN33840
Cat.No: T68565
Synonym:
Target:
Zilpaterol hydrochloride
Cat.No: T20590
Synonym:
Target:
6-Azathymine acid
Cat.No: T38813
Synonym:
Target:
Galanin-Like Peptide (rat)
Cat.No: T80146
Synonym:
Target: Neuropeptide Y Receptor
Oxyntomodulin
Cat.No: TP1976
Synonym: 胃泌酸调节素,Oxyntomodulin (porcine, bovine)
Target:
Orexin A (human, rat, mouse) (TFA)
Cat.No: TP1550
Synonym:
Target:
Apelin-12
Cat.No: T39823
Synonym:
Target:
SN00799639
Cat.No: T70938
Synonym:
Target:
Galanin (1-19), human
Cat.No: TP1529
Synonym:
Target:
Galanin-Like Peptide (human)
Cat.No: T80144
Synonym:
Target: Neuropeptide Y Receptor
[Pro3]-GIP (Mouse)
Cat.No: TP2020
Synonym:
Target:
Neuropeptide Y (3-36) (porcine)
Cat.No: T76355
Synonym:
Target:
Apelin-36(human)
Cat.No: TP2093
Synonym: Apelin-36 (human)
Target:
LH 21
Cat.No: T21811
Synonym:
Target:
Apelin-36(rat, mouse)
Cat.No: TP2094
Synonym: Apelin-36 (rat, mouse)
Target:
26Rfa, Hypothalamic Peptide, human
Cat.No: TP1542
Synonym:
Target:
BMS-814580
Cat.No: T26860
Synonym:
Target:
[(pF)Phe4]Nociceptin(1-13)NH2
Cat.No: TP1885
Synonym:
Target:
CART (1-39), Human, Rat
Cat.No: T76365
Synonym:
Target:
HS014 TFA
Cat.No: T75853
Synonym:
Target:
Pheromonotropin (pseudaletia separata)
Cat.No: T81491
Synonym: Pss-PT
Target:
(S)-V-0219
Cat.No: T73081
Synonym:
Target:
CRSP-1
Cat.No: TP2049
Synonym:
Target:
Jacaric Acid
Cat.No: T36099
Synonym:
Target:
(S)-V-0219 hydrochloride
Cat.No: T74265
Synonym:
Target:
Peraclopone
Cat.No: T68219
Synonym:
Target:
CRSP-1 acetate(697327-12-1 Free base)
Cat.No: TP2049L
Synonym:
Target:
Neuromedin U-25 (human) (trifluoroacetate salt)
Cat.No: T35598
Synonym:
Target:
9-PAHSA
Cat.No: T36590
Synonym:
Target:
12-PAHSA
Cat.No: T36586
Synonym:
Target:
Alphitonin
Cat.No: T37809
Synonym:
Target:
Galanin (rat, mouse) (trifluoroacetate salt)
Cat.No: T37718
Synonym: GAL (rat, mouse),Galanin (rat, mouse) (trifluoroacetate salt)
Target:
Cat. No. Product Name Target Signaling Pathways
T8275 (+)-Isopulegol

异苏木精,異洋薄[荷]醇

Parasite Microbiology/Virology
(+)-Isopulegol 是加拿大薄荷树中发现的一种萜类,是T. confusum 成虫和T. granarium 幼虫的摄食引诱剂,对S. granarius 和T. confusum 的成虫具有刺激作用。
TN1402 Arjungenin

阿江榄仁素,2ALPHA,19ALPHA,23-三羟基齐墩果酸

Antifection; Immunology/Inflammation related Immunology/Inflammation; Microbiology/Virology
Arjungenin, a triterpene derived from Terminalia arjuna, exhibits insect feeding-deterrent and growth inhibitory properties.
T3S1892 Crassicauline A

粗茎乌头碱甲,Crassicauline I

Others Others
Crassicauline A (Crassicauline I) 是一种乌头根中具有生物活性的生物碱。它对赤拟谷盗成虫具有拒食剂作用,其 EC50=1134.5 ppm。
TN3601 Carminic acid

ROS Immunology/Inflammation
Carminic acid 是天然红色色素,是球虫染料家族中的一种。
TN6835 (E)-β-Farnesene

(6E)-7,11-dimethyl-3-methylidenedodeca-1,6,10-triene,trans-β-Farnesene

Antifungal Microbiology/Virology
(E)-β-Farnesene (trans-β-Farnesene) 是一种存在于 Phlomis aurea Decne中的倍半萜烃,是许多蚜虫报警信息素的主要成分,可中断蚜虫摄食。(E)-β-Farnesene 通过破坏昆虫激素平衡来损害 Chilo suppressalis 幼虫的发育和存活。
T6S0071 Fraxinellone

HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物,是PD-L1抑制剂,可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1,有用于癌症免疫的潜力。
TN1064 Aristolochic acid C

Others Others
Aristolochic acid C 是马兜铃酸的一种衍生物,是磷脂酶 A 抑制剂。Aristolochic acid C 作用于拟南芥,可破坏间期细胞的周质微管列阵和抑制根生长。
T4776 Glycerol

Glycerin,甘油

Endogenous Metabolite Metabolism
Glycerol 是甘油三酯(即脂肪和油)和磷脂的重要成分。它在食品工业中被广泛用作甜味剂和保湿剂以及药物制剂。
TN4403 Lactupicrin

Antifection Microbiology/Virology
Lactupicrin has antimicrobial and anti-cancer effects, it also protect the plant from insect feeding.
TN1401 Arjunetin

Others Others
Arjunetin, an insect feeding-deterrent and growth inhibitor, shows antioxidant and anti-inflammatory activities.
TN4994 Sequirin C

Others Others
Sequirin C can inhibit feeding behavior.
TN2522 1,7-Diphenyl-4-hepten-3-one

Others Others
1,7-Diphenyl-4-hepten-3-one has feeding deterrent activities against Tribolium castaneum.
T78482 Ajugacumbin B

Ajugacumbin B作为一种抗食性化合物,对Helicoverpa armigera具有显著的拒食效果,其EC50值为15.2 μg/cm2。
TN4026 Eucamalol

Others Others
Eucamolol exhibits significant repellent activity against Aedes albopictus, and inhibits its feeding as well as DEET, is effective repellent (75%) up to 3 h after exposure to mosquito.
T82300 Gluconasturtiin

Gluconasturtiin 作为P. maculipennis幼虫的摄食诱导剂,但其高浓度会对幼虫产生毒害效应。
TN2723 Jatrophane 3

Antifection Microbiology/Virology
Jatrophane 4 (2R*,3R*,4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera), with an EC50 value of 0.36 ug/cm2.
TN2728 Jatrophane 4

Antifection Microbiology/Virology
Jatrophane 3 (2R*,3R*, 4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,14-triacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxy-9-nicotinoyloxyjatropha-6(17),11E-diene) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera), with an EC50 value of 0.43 ug/cm2.
TN2727 Jatrophane 2

P-gp; Antifection Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6(17),11E-diene (Jatrophane 2 ) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera). Jatrophane 2 also demonstrates the mo
T83440 17-Hydroxyjolkinolide A

Caudicifolin,Fischeriana A

17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) 是一种从大戟根中提取的昆虫摄食抑制剂。它能有效诱导玉米夜蛾 (S. zeamais) 与赤霉成虫 (T. castaneum) 对谷物产生拒食行为,其EC50s 值分别为 631.9 ppm 和 656.5 ppm。
TN4691 Octadecyl caffeate

Others Others
z-Octadecyl caffeate may have pain-relieving activity. Octadecyl caffeate and coptisonine can stimulate glucose uptake at 25 and 50 ug/mL. Octadecyl caffeate and octadecyl coumarate applied to the surface of susceptible varieties in laboratory bioassays r
TN5580 Rediocide A

Rediocide A, an insecticide, can inhibit calcium mobilization in Drosophila G-protein- coupled receptors (GPCR)s other than methuselah, it can induce GPCR desensitization and internalization, and such effects are mediated by the activation of conventional
TN5228 Vestitol

Antifection Microbiology/Virology
Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemica...

天然产物

(+)-Isopulegol
Cat.No: T8275
Synonym: 异苏木精,異洋薄[荷]醇
Target: Parasite
Arjungenin
Cat.No: TN1402
Synonym: 阿江榄仁素,2ALPHA,19ALPHA,23-三羟基齐墩果酸
Target: Antifection, Immunology/Inflammation related
Crassicauline A
Cat.No: T3S1892
Synonym: 粗茎乌头碱甲,Crassicauline I
Target: Others
Carminic acid
Cat.No: TN3601
Synonym:
Target: ROS
(E)-β-Farnesene
Cat.No: TN6835
Synonym: (6E)-7,11-dimethyl-3-methylidenedodeca-1,6,10-triene,trans-β-Farnesene
Target: Antifungal
Fraxinellone
Cat.No: T6S0071
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1
Aristolochic acid C
Cat.No: TN1064
Synonym:
Target: Others
Glycerol
Cat.No: T4776
Synonym: Glycerin,甘油
Target: Endogenous Metabolite
Lactupicrin
Cat.No: TN4403
Synonym:
Target: Antifection
Arjunetin
Cat.No: TN1401
Synonym:
Target: Others
Sequirin C
Cat.No: TN4994
Synonym:
Target: Others
1,7-Diphenyl-4-hepten-3-one
Cat.No: TN2522
Synonym:
Target: Others
Ajugacumbin B
Cat.No: T78482
Synonym:
Target:
Eucamalol
Cat.No: TN4026
Synonym:
Target: Others
Gluconasturtiin
Cat.No: T82300
Synonym:
Target:
Jatrophane 3
Cat.No: TN2723
Synonym:
Target: Antifection
Jatrophane 4
Cat.No: TN2728
Synonym:
Target: Antifection
Jatrophane 2
Cat.No: TN2727
Synonym:
Target: P-gp, Antifection
17-Hydroxyjolkinolide A
Cat.No: T83440
Synonym: Caudicifolin,Fischeriana A
Target:
Octadecyl caffeate
Cat.No: TN4691
Synonym:
Target: Others
Rediocide A
Cat.No: TN5580
Synonym:
Target:
Vestitol
Cat.No: TN5228
Synonym:
Target: Antifection
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