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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T0509	Cloxiquine 5-Chloro-8-quinolinol,氯羟喹,Dermofungin,Dermofongin,5-氯-8-羟基喹啉	Antibacterial; Antibiotic; PPAR; Parasite; Antifungal	DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Cloxiquine (Dermofongin) 具有抗菌，抗真菌和抗阿米巴虫的作用。它还可通过激活 PPARγ抑制黑素瘤细胞的生长和转移。它可研究结核病和皮肤病。
T1561	Clobetasol propionate Dermovate,Clobetasol 17-propionate,CGP9555,Temovate,丙酸氯倍他索,CCl 4725	Glucocorticoid Receptor; P450	Endocrinology/Hormones; Metabolism
	Clobetasol propionate (CGP9555) 是CYP3A5的选择性抑制剂(IC50:0.206 μM)，而对 CYP3A4 或其他主要 CYP 无抑制作用。它是皮质类固醇，对于牛皮癣和其他皮肤病具有潜在的研究价值。
T14981	Clobetasone butyrate	Glucocorticoid Receptor	Endocrinology/Hormones
	Clobetasone butyrate 是糖皮质类固醇，特别是在皮肤上，具有局部抗炎活性。它可用于改善皮质类固醇反应性症状，如特应性皮炎、牛皮癣。
T14154	Alclometasone 7a-Chloro-16a-methyl prednisolone
	Alclometasone (7a-Chloro-16a-methyl prednisolone), a glucocorticoid, inhibits leukocytes from releasing pro-inflammatory mediators. It is effective in treating corticosteroid-responsive dermatoses such as atopic dermatitis, psoriasis, allergic dermatitis, and eczema [1].
T68475	AO-1535
	AO-1535 is a semisynthetic monoglycosylceramide derived from O-glycosilated sphingosine. It has been shown to inhibit superoxide production by macrophages suggesting a potential clinical application of AO 1535 in the treatment of inflammatory dermatoses.
T36379	Halometasone
	Halometasone is a synthetic corticosteroid.1,2Formulations containing halometasone have been used in the treatment of psoriasis vulgaris and eczematous dermatoses. 1.de la Brassine, M., Kint, A., Lachapelle, J.M., et al.Halomethasone (C 48.401-Ba) for the topical treatment of common dermatosesJ. Int. Med. Res.12(5)307-309(1984) 2.Zhu, J.-W., Wu, X.-J., Lu, Z.-F., et al.Role of VEGF receptors in normal and psoriatic human keratinocytes: Evidence from irradiation with different UV sourcesPLoS One8...

化合物

Cloxiquine

Cat.No: T0509

Synonym: 5-Chloro-8-quinolinol,氯羟喹,Dermofungin,Dermofongin,5-氯-8-羟基喹啉

Target: Antibacterial, Antibiotic, PPAR, Parasite, Antifungal

Clobetasol propionate

Cat.No: T1561

Synonym: Dermovate,Clobetasol 17-propionate,CGP9555,Temovate,丙酸氯倍他索,CCl 4725

Target: Glucocorticoid Receptor, P450

Clobetasone butyrate

Cat.No: T14981

Synonym:

Target: Glucocorticoid Receptor

Alclometasone

Cat.No: T14154

Synonym: 7a-Chloro-16a-methyl prednisolone

Cat. No.	Product Name	Target	Signaling Pathways
T0070	Pentoxifylline Oxpentifylline,PTX,己酮可可碱,BL-191	HIV Protease; PDE; Adenosine Receptor; Autophagy	Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Pentoxifylline (PTX) 是一种具有口服活性的磷酸二酯酶非选择性抑制剂，具有免疫调节、抗炎、抗纤溶、抗增殖和血液流变学改善作用。它可研究周围血管疾病、脑血管疾病和其他一些涉及局部微循环缺陷的疾病。
T1068	Dithranol 1,8,9-trihydroxyanthracene,cignoline,蒽林,Anthralin	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Dithranol (cignoline) 是蒽醌衍生物，可破坏线粒体功能和结构，用于治疗皮肤病。
T0330	Diphenhydramine hydrochloride 盐酸苯海拉明,Diphenhydramine HCl,DPH	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Diphenhydramine hydrochloride (DPH) 是一种组胺 H1 拮抗剂，用作镇咳药和止吐药。它还用于治疗瘙痒和皮肤病、过敏反应、抗帕金森病、催眠药和普通感冒制剂的成分。