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31

抑制剂 & 化合物

16

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5046	Haloxyfop Haloxyfop Acid,(±)-Haloxyfop,吡氟氯禾灵	Others; Acetyl-CoA Carboxylase	Metabolism; Others
	Haloxyfop (Haloxyfop Acid) 是有效的芳氯氧苯氧丙酸除草剂，广泛应用于阔叶作物的野草。对玉米幼苗叶绿体中乙酰辅酶 A 羧化酶 (EC 6.4.1.2) 具有抑制作用，IC50为 0.5 μM，而对豌豆中该酶无影响。
T19914	Chlorothalonil DAC 2787,Daconil,Daconil M,百菌清	Antifungal	Microbiology/Virology
	Chlorothalonil (DAC 2787) 是一种高效低毒广谱的杀菌剂，广泛用于防治果树、蔬菜菜叶等多种害虫，对水稻、小麦、棉花等多种病害，也具有较好的防治效果。
T64349	Necroptosis-IN-3 Cyclohexanecarboxamide, N-(2-thienylmethyl)-	Necroptosis	Apoptosis
	Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-)(Compound 69) 是一种坏死性凋亡 (necroptosis) 抑制剂，抑制 TNF-α 诱导的坏死性凋亡。Necroptosis-IN-3(Compound 69) 也抑制 11β-HSD1。
TP1410	Cecropin A	Antibacterial; Antibiotic	Microbiology/Virology
	Cecropin A 是37个氨基酸组成的线性多肽，表现出抗菌、抗炎和抗肿瘤的功效。
T9305	Necroptosis-IN-1	RIP kinase	Apoptosis; NF-κB
	Necroptosis-IN-1 是一种 RIPK1 坏死性凋亡抑制剂。它是 Necrostatin-1 的类似物。
TP1313L	Cecropin B acetate Cecropin B acetate(80451-05-4 Free base)	P450; Retinoid Receptor; Parasite	Metabolism; Microbiology/Virology
	Cecropin B acetate 通过破坏 PXR/类视黄醇 X 受体 α (RXR-α) 复合物与 DNA 序列的结合来诱导 NF-κB 活化并抑制 CYP3A29。 Cecropin B acetate 具有很强的抗菌活性。
T38648L	Cecropin P1, porcine acetate	Endogenous Metabolite	Metabolism
	Cecropin P1, porcine acetate 是一种在 Hyalophora cecropia 和猪肠道中发现的抗菌肽。
T10750	Cecropin A TFA (80451-04-3 free base) Cecropin A TFA	Others	Others
	Cecropin A TFA is an antimicrobial polypeptide isolated from Hyalaphora cecropia pupae with anti-inflammatory, anti-bacterial, and anti-cancer activity.
T76468	Cecropin A (1-7)-Melittin A (2-9)
	Cecropin A (1-7)-Melittin A (2-9) 为一种具抗菌效能的肽，对广谱革兰氏阳性及革兰氏阴性需氧菌显示出显著的抗菌活性，同时展现出抗疟能力，而无蜂毒肽所致的不良溶血现象。
T125236	Scrophularoside A5
	Scrophularoside A5 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125236，CAS号为 240820-17-1。
T126316	Scropolioside B
	Scropolioside B 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126316，CAS号为 116084-90-3。
TP1313	Cecropin B
	Cecropin B is a small antibacterial peptide from the giant silkmoth, Hyalophora cecropia.
T124124	Cropodine
	Cropodine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124124。
T19411	Macropa-NH2 diester	Others	Others
	Macropa-NH2 diester is a compound can be used for imaging during the investigation of cancer.
T25811	Micropeptin 478B
	Micropeptin 478B is a plasmin inhibitor from the Cyanobacterium Microcystis aeruginosa.
T11938	Macropa-NH2 hydrochloride	Others	Others
	Macropa-NCS, conjugated to Anti-Human HER2 and the prostate-specific membrane antigen-targeting compound RPS-070, serves as a promising therapeutic radionuclide for soft-tissue metastases treatment. Its precursor, Macropa-NH2 hydrochloride, facilitates its synthesis.
T25810	Micropeptin 478A Micropeptin 478 A,Micropeptin 478-A
	Micropeptin 478A is a plasmin inhibitor from the Cyanobacterium Microcystis aeruginosa.
T11938L	Macropa-NH2	Others	Others
	Macropa-NH2 是 macropa 双功能类似物，是一种常与抗体偶联的载体分子，常作为螯合剂使用，参与癌症研究。
T125235	Scrophularoside A8
	Scrophularoside A8 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125235，CAS号为 240820-44-4。
T76233	Cecropin D
	Cecropin D为具多功能性的抗菌肽，对革兰氏阴性菌和革兰氏阳性菌均有效，MIC值为4.55 μg/mL。此外，Cecropin D还展现出抗病毒、抗真菌、抗肿瘤及免疫调节的作用。
T126343	Cecropiacic acid
	Cecropiacic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126343，CAS号为 114175-98-3。
T11936	Macropa-NCS	Others	Others
	Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070.
T38648	Cecropin P1, porcine
	Cecropin P1, porcine is an antibacterial peptide originally identified in moths (Hyalophora cecropia) and later in pig intestine.
T7110	Thifluzamide	Antifungal	Microbiology/Virology
	Thifluzamide 是广泛用于防治作物病害的杀菌剂。
T14527	Benfluralin
	Benfluralin 是一种除草剂，是一种农用化学品，可用作芽前除草剂。用于控制一系列粮食和非粮食作物中的草和其他杂草。
T40871	Diclobutrazol
	Diclobutrazol is a potent systemic fungicide effective against rusts, powdery mildews, and other fungal phytopathogens. It exhibits high activity in controlling various crop diseases, making it a valuable pesticide option.
T41034	Triclopyricarb 氯啶菌酯,SYP-7017
	Triclopyricarb (SYP-7017) is a strobilurin fungicide that can be used in crops disease control. Triclopyricarb inhibits mycelial growth with EC 50 values ranged from 0.006 μg/mL to 0.047 μg/mL.
T19989	Imazamethabenz Imazamethabenz-methyl,Assert,HSDB 6675,Dagger
	Imazamethabenz is a herbicide. Imazamethabenz-methyl is used on cereals and sunflowers, especially against wild oat. Activity and selectivity are due to differential de-esterification to the active parent acid in target and crop species.
T38272	Thiacloprid	AChR; Parasite	Microbiology/Virology; Neuroscience
	Thiacloprid 属于氯烟碱类杀虫剂，主要用于防治蔬菜和果园中的蚜虫。它会破坏 DNA 的稳定性，通过疏水或氢相互作用，结合到小沟槽中，改变 DNA 的结构和稳定性。
T73978	Valienamine
	Valienamine为α-葡萄糖苷酶抑制剂，为众多天然糖苷酶抑制剂，包含用于作物保护的validamycin A及治疗糖尿病的阿卡波糖，的关键活性成分。
T37519	Diquat (bromide)
	Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).1Diquat administration has been used to induce oxidative stressin vitroand in animal models.2,3,4It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.2Form...

化合物

Cat.No: T5046

Synonym: Haloxyfop Acid,(±)-Haloxyfop,吡氟氯禾灵

Target: Others, Acetyl-CoA Carboxylase

Cat.No: T19914

Synonym: DAC 2787,Daconil,Daconil M,百菌清

Target: Antifungal

Necroptosis-IN-3

Cat.No: T64349

Synonym: Cyclohexanecarboxamide, N-(2-thienylmethyl)-

Target: Necroptosis

Cat.No: TP1410

Target: Antibacterial, Antibiotic

Necroptosis-IN-1

Cat.No: T9305

Target: RIP kinase

Cecropin B acetate

Cat.No: TP1313L

Synonym: Cecropin B acetate(80451-05-4 Free base)

Target: P450, Retinoid Receptor, Parasite

Cecropin P1, porcine acetate

Cat.No: T38648L

Target: Endogenous Metabolite

Cecropin A TFA (80451-04-3 free base)

Cat.No: T10750

Synonym: Cecropin A TFA

Target: Others

Cecropin A (1-7)-Melittin A (2-9)

Cat.No: T76468

Scrophularoside A5

Cat.No: T125236

Scropolioside B

Cat.No: T126316

Cat.No: TP1313

Cat.No: T124124

Macropa-NH2 diester

Cat.No: T19411

Target: Others

Micropeptin 478B

Cat.No: T25811

Macropa-NH2 hydrochloride

Cat.No: T11938

Target: Others

Micropeptin 478A

Cat.No: T25810

Synonym: Micropeptin 478 A,Micropeptin 478-A

Cat.No: T11938L

Target: Others

Scrophularoside A8

Cat.No: T125235

Cat.No: T76233

Cecropiacic acid

Cat.No: T126343

Cat.No: T11936

Target: Others

Cecropin P1, porcine

Cat.No: T38648

Cat.No: T7110

Target: Antifungal

Cat.No: T14527

Cat.No: T40871

Cat.No: T41034

Synonym: 氯啶菌酯,SYP-7017

Cat.No: T19989

Synonym: Imazamethabenz-methyl,Assert,HSDB 6675,Dagger

Cat.No: T38272

Target: AChR, Parasite

Cat.No: T73978

Diquat (bromide)

Cat.No: T37519

Cat. No.	Product Name	Target	Signaling Pathways
T3S0027	Picropodophyllotoxin AXL 1717,Picropodophyllin,苦鬼臼毒素	IGF-1R	Tyrosine Kinase/Adaptors
	Picropodophyllotoxin (AXL 1717) 是一种环木脂素生物碱，存在于五月树(Podophyllum peltatum) 中，是一种具有潜在抗肿瘤活性的胰岛素样生长因子 1 受体 (IGF1R) 的小分子抑制剂。它特异性抑制 IGF1R 的活性并下调细胞表达，而不干扰其他生长因子受体的活性，例如胰岛素受体、表皮生长因子、血小板衍生生长因子、成纤维细胞生长因子和肥大/干细胞生长因子 (KIT) ）。该药剂在抑制肿瘤细胞增殖和诱导肿瘤细胞凋亡方面显示出有效的活性。 IGF1R 是一种在多种人类癌症中过度表达的受体酪氨酸激酶，在多种癌细胞的生长和存活中起关键作用。
TN2071	Picropodophyllone (-)-Picropodophyllone,Picropodopyllotoxone,苦鬼臼脂毒酮	Others	Others
	Picropodophyllone 是一种从Podophyllum hexandrum 的叶子中分离出来的芳基四氢呋喃木脂素，具有抗真菌活性。
T6943	Picropodophyllin AXL1717,苦鬼臼脂素,Picropodophyllin (PPP),Picropodophyllotoxin,PPP,苦鬼臼毒素	Apoptosis; IGF-1R	Apoptosis; Tyrosine Kinase/Adaptors
	Picropodophyllin (Picropodophyllin (PPP)) 是一种选择性的胰岛素样生长因子-1受体抑制剂，IC50为1 nM。
TN2070	Picropodophyllol	Others	Others
	Picropodophyllol 是从 Dysosma versipellis 的根中分离出来的天然产物。
T75974	Cecropin A TFA
	Cecropin A TFA 是由 37 个氨基酸残基构成的线性抗菌肽，从 Hyalaphora cecropiapupae 得到，具有抗菌、抗炎和抗癌作用。
TN2466	Isopicropodophyllone	Others	Others
	Isopicropodophyllone is a natural product from Sinopodophyllum hexandrum (Royle) Ying
T81463	Picropodophyllin-4-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside
	Picropodophyllin-4-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (compound 17)是一种从中华鬼臼根及根茎中提取的木脂素化合物。
TN6021	Daphmacropodine
	Daphmacropodine是一种天然产物，属于交让木科虎皮楠属，其产品编号为 TN6021，CAS号为 39729-21-0。Daphmacropodine可用作对照参考。
TN4484	Macrophylline	Others	Others
	Macrophylline A shows weak inhibitory action on KCl-induced contraction.
T81462	Picropodophyllin-β-D-glucoside
	Picropodophyllin-β-D-glucoside (compound 3) 是从中药植物提取的一种鬼臼毒素葡萄糖苷。
TN6558	Macrophylloside D
	Macrophylloside D 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6558，CAS号为 179457-69-3。
T75622	β-Apopicropodophyllin
	β-Apopicropodophyllin 是一种天然产物，可以从Hyptis wticillata 中分离得到。β-Apopicropodophyllin 通过诱导微管破坏、DNA 损伤、细胞周期停滞和 ER 应激来诱导细胞凋亡。β-Apopicropodophyllin 可用于癌症研究。
T20754	Deltamethrin Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974	Others	Others
	Deltamethrin (RU 22974) 是一种具有神经毒性的拟除虫菊酯杀虫剂，在大鼠中能够产生一系列可逆的运动症状(如包括后肢僵硬、舞蹈性关节炎)。
T3897	Isoschaftoside	Anti-infection; Antifungal	Microbiology/Virology
	Isoschaftosid 是从 Desmodium uncinatum 根部分泌物中提取的 c- 糖基黄酮类天然产物，有抗肿瘤、抗氧化和抗菌活性，它还对 M. incognita 具有很强的杀线虫活性。
TN4040	Eupatoriochromene	Antifection	Microbiology/Virology
	Eupatoriochromene retard seed germination , reduced radicle and hypocotyl growth of weed and crop plant seedlings and increased adventitious root formation of mung bean cuttings. Eupatoriochromene has insecticidal activity, it exhibits toxicity againstCul
TN3930	Encecalin	ATPase	Membrane transporter/Ion channel
	Encecalin and demethylencecalin are major phytotoxic compounds isolated from Helianthella quinquenervis (Hook) A Gray (Asteraceae), they inhibit photosystem II (from water to 2,5-dibromo-3-methyl-6-isopropyl-1,4 p-benzo-quinone).They retard seed germinati

天然产物

Picropodophyllotoxin

Cat.No: T3S0027

Synonym: AXL 1717,Picropodophyllin,苦鬼臼毒素

Target: IGF-1R

Picropodophyllone

Cat.No: TN2071

Synonym: (-)-Picropodophyllone,Picropodopyllotoxone,苦鬼臼脂毒酮

Target: Others

Picropodophyllin

Cat.No: T6943

Synonym: AXL1717,苦鬼臼脂素,Picropodophyllin (PPP),Picropodophyllotoxin,PPP,苦鬼臼毒素

Target: Apoptosis, IGF-1R

Picropodophyllol

Cat.No: TN2070

Target: Others

Cat.No: T75974

Isopicropodophyllone

Cat.No: TN2466

Target: Others

Picropodophyllin-4-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside

Cat.No: T81463

Daphmacropodine

Cat.No: TN6021

Cat.No: TN4484

Target: Others

Picropodophyllin-β-D-glucoside

Cat.No: T81462

Macrophylloside D

Cat.No: TN6558

β-Apopicropodophyllin

Cat.No: T75622

Cat.No: T20754

Synonym: Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974

Target: Others

Cat.No: T3897

Target: Anti-infection, Antifungal

Eupatoriochromene

Cat.No: TN4040

Target: Antifection

Cat.No: TN3930

Target: ATPase

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