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87

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19376	Ioversol MP-328,碘佛醇	Others	Others
	Ioversol (MP-328) 是一种非离子碘化造影剂 (CM)，不损伤动物的血脑屏障 (BBB)，可用于动物实验的 CT 扫描或 x-ray。
T8406	Gadobutrol ZK 135079,钆布醇	Others	Others
	Gadobutrol 是一种非离子的顺磁造影剂，可用于磁共振成象（MRI）。
T1554	Iohexol	Mitophagy; Autophagy	Autophagy
	Iohexol 是一种造影剂。Iohexol 的渗透压从322 mOsm/kg(约为血浆的1.1倍)到844 mOsm/kg(约为血液的3倍)不等。
T16471	Perflubron Perfluorooctyl bromide,全氟溴辛烷,PFOB	Others	Others
	Perflubron (Perfluorooctyl bromide) 是一种用于磁共振成像和超声检查的造影剂，可以与卵磷脂(EYP)一起乳化，并表现出较迅速的排泄特性。
T19332	Gadopentetic acid gadolinium complex,钆喷酸,Gd-DTPA	Others	Others
	Gadopentetic acid (gadolinium complex) 是一种顺磁性造影剂，通常通过静脉内注射 (i.v.) 的方式用于 DCE-MRI 研究。
T1576	Iopamidol SQ-13396,Niopam,Iopamiron,Iopamiro,碘帕醇,B-15000,Isovue	Others	Others
	Iopamidol (SQ-13396) 是一种 benzenedicarboxamide 化合物。它具有放射性不透明介质、环境污染物和异种生物的作用。
T19799	Ioxitalamic Acid 碘羟拉酸,Telebrix,Vasobrix,Acidum Joxitalamicum	Others	Others
	Ioxitalamic Acid (Acidum Joxitalamicum) 是一种医用造影剂，可在医学成像中增强体内结构或流体的对比度。
T0960	Iopanoic acid 碘番酸,Iodopanoic acid,Acidum iopanoicum	Others	Others
	Iopanoic acid (Acidum iopanoicum) 是5'-脱碘酶的抑制剂，也是一种碘造影剂。
T1522	Iopromide 碘普罗胺,Iopromidum,Ultravist	Others	Others
	Iopromide (Iopromidum) 是用于血管内的低渗透、非离子造影剂。
T0803	Acetrizoic acid Urokon,醋碘苯酸,Opacaron,Acetrizoesaeure	Others	Others
	Acetrizoic acid (Urokon) 是小分子化合物，可用作显影剂。
T1196	Iodixanol 碘克沙醇,Visipaque,Acupaque	Others	Others
	Iodixanol (Visipaque) 是含碘的非离子放射性造影剂。
T5161	Gadodiamide	Others	Others
	Gadodiamide 是一种含钆造影剂，可用于医学成像。
T1319	Sodium diatrizoate Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,泛影酸钠,Diatrizoate sodium,amidotrizoate sodium,Triombrin	Apoptosis; Others	Apoptosis; Others
	Sodium diatrizoate (Hypaque sodium) 是一种碘化不透射线 X 射线造影剂，在血管造影、尿路造影和放射造影中用作诊断辅助工具。它可通过钙失调诱导线粒体更新和氧化应激，激活细胞凋亡。
T0271	Iodipamide Iodipamic acid,胆影酸,Adipiodone	Others	Others
	Iodipamide (Iodipamic acid) 是一种三碘苯甲酸酯衍生物，也是一种离子二聚剂，可用于诊断成像。
T31786	Ferumoxytol Magnetic Black,Black Iron BM,Magnetic oxide,Black Gold F 89,11557 Black	Others	Others
	Ferumoxytol (Magnetic Black) 是一种非钆基造影剂，可用于磁共振成像应用，可用于治疗缺铁性贫血和慢性肾病。
T20637	Diatrizoate meglumine Reno,Renografin,Renovist,泛影葡胺,Hypaque,Renocal,Sinografin	Others	Others
	Diatrizoate meglumine (Renocal) 是泛影酸盐的葡甲胺盐，它是一种有机的、碘化的、不透射线的 X 射线造影剂，用于放射诊断。
T19333	Gadoteridol ProHance,SQ-32692,钆特醇,Gd-HP-DO3A	Others	Others
	Gadoteridol (Gd-HP-DO3A) 是含钆基的 MRI 造影剂，可用于中枢神经系统成像。
T0503	Meglumine Meglumin,Methylglucamin,葡甲胺,葡萄糖甲胺,Methylglucamine	Others	Others
	Meglumine (Meglumin) 是一种氨基糖，来源于山梨糖醇。其中常在药物中用作赋形剂，并与碘代化合物葡甲胺和碘帕胺葡甲胺等造影剂中的碘化化合物一起使用。
T20110	Ethylene thiourea ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲	Others	Others
	Ethylene thiourea (NCIC03372) 是一种用于水果和蔬菜生产的农药。它还用作基于质子化学交换依赖性饱和转移的 MRI 研究的新型造影剂。
T1395	Diatrizoic Acid Diatrizoate,泛影酸,Amidotrizoic acid	Apoptosis; Others	Apoptosis; Others
	Diatrizoic Acid (Amidotrizoic acid) 是一种有机碘化不透射线 X 射线造影剂，用于放射诊断，具有对气道进行放射照相成像的潜力。它通过钙失调诱导线粒体更新和氧化应激，激活细胞凋亡。
T1937	Spautin-1 Spautin 1	Apoptosis; DUB; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
	Spautin-1是一种特异性自噬抑制剂，可抑制泛素特异性肽酶 USP10和 USP13，IC50s 约为0.6到0.7 μM。
T0438	Proflavine Hemisulfate 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate,硫酸原黄素	Others; Potassium Channel; DNA; Thrombin; Antibacterial; Autophagy	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Others; Proteases/Proteasome
	Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) 是一种 DNA 嵌入剂，也是一种吖啶染料。它是抗菌剂，也可作为 Kir3.2孔阻滞剂，可研究与 Kir3.2 相关的神经系统疾病。
T15378L	Gemcitabine elaidate hydrochloride CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride	Others	Others
	Gemcitabine elaidate (CP-4126) hydrochloride 是 Gemcitabine 的亲脂性前药。Gemcitabine elaidate hydrochloride 通过酯酶转化为 Gemcitabine 以被磷酸化。Gemcitabine elaidate hydrochloride 可以口服给药，具有抗肿瘤活性。
T4506	Gadopentetate dimeglumine Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,钆喷酸葡胺,Gadopentetic acid dimeglumine salt	Others	Others
	Gadopentetate dimeglumine (Gd-DTPA) 可用于核磁共振成像 (MRI) 中，使血管、器官和其他非骨组织能够更清晰地被看到。
T15367	Gadoxetate Disodium Gd-EOB-DTPA Disodium,钆塞酸二钠,ZK 139834	Others	Others
	Gadoxetate Disodium 是一种肝胆系统中磁共振成像 (MRI) 中的造影剂，能够在正常的功能性肝细胞中累积，可用于局灶性肝脏病变（如肝细胞癌或 T1 加权成像的肝转移）的研究。
T20870	IR-820 IR 820,IR820,New Indocyanine Green
	IR-820 (New Indocyanine Green) 是一种近红外染料，具有很好的稳定性、良好的显色性和出色的荧光穿透性。IR-820 是一种红外血池造影剂，用于检测和量化活体动物的病变组织。IR-820 的最大 Ex 和 Em 分别为 710 纳米和 820 纳米。
T19375	Iotalamic acid Iothalamic acid,碘他拉酸	Others	Others
	Lotalamic acid is a molecule used as a contrast medium.
T35133	WIN-68056 WIN 68056
	WIN-68056 is a wetting agent in x-ray contrast compositions.
T33369	Metrizamide Amipak,Amipaque
	Metrizamide is a nonionic radiopaque contrast agent.
T28826	Sodium Ioxaglate P-286,MP 302,MP-302,Ioxaglic acid,P 286
	Sodium Ioxaglate is used as a contrast agent.
T34699	Sprodiamide S 043,S043,S-043
	Sprodiamide is a magnetic susceptibility-based MRI contrast agent.
T16067	Metrizoic acid 甲泛影酸,Metrizoate	Others	Others
	Metrizoic acid is an ionic contrast medium. Metrizoic acid displays high osmolality and has a risk of inducing allergic reactions.
T32182	Iopydone NSC 135284,NSC135284,NSC-135284,Hytrast,Iopydonum
	Iopydone is an iodinated contrast dye.
T36008	Nebentan potassium
	Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan potassium inhibits [125I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively[1]. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo[2]. Nebentan potassium inhibits the specific binding of [125I] endothelin-1 to endothelin ETA and ETB re...
T20132	Perflexane 全氟己烷,Fluorinert FC72	Others	Others
	Perflexane (Fluorinert FC72) 被开发为超声造影剂。
T32183	Iosimenol MP-3047-04,ICJ 3393,ICJ-3393,BP-13
	Iosimenol 是一种氨基苯甲酸和造影剂。
T19413	Mangafodipir trisodium	Others	Others
	Mangafodipir trisodium can enhance contrast in magnetic resonance imaging (MRI) of the liver, is a contrast agent delivered intravenously.
T33322	Methiodal sodium Abrodan,Abrodil,Diagnorenol,Conturex,Iodomethanesulfonic acid sodium salt,Abroden
	Methiodal sodium is a crystalline salt used as a radiopaque contrast medium in intravenous urography.
T33853	P 569 P569,P-569
	P 569 is an MRI contrast medium.
T32167	Iodamide BRN 2175358,Iodamidum,Ametriiodic acid
	Iodamide can be used as a contrast medium.
T32177	Ioforminol GE-145,GE145,AN 113111,AN113111,AN-113111,GE 145
	Ioforminol, also known as GE-145 and AN-113111, is a new low-osmolar dimeric radiographic contrast agent. GE-145 exhibits similar preclinical properties to other dimeric radiographic contrast media. In addition, the low osmolality enables an iso-osmolar f
T31507	Diodone Iodopyracet
	Diodone is an ionic monomeric contrast medium that was formerly used for a variety of diagnostic procedures.
T32867	Lophiraic acid
	Lophiraic acid is isolated from Lophira alata; in contrast to lophirone A, it does not have any biological activity.
TNU0613	S-2-(4-aminobenzyl)-diethylenetriamine penta-t-butyl acetate
	Super-chelating agent& MRI contrast agent
T32178	Ioglucomide MP 8000,MP-8000
	Ioglucomide is an iodinated nonionic contrast medium directed primarily toward myelographic use.
T19377	Ioxilan	Others	Others
	Ioxilan is a low-osmolar, nonionic, and tri-iodinated diagnostic contrast agent used for excretory urography and contrast-enhanced computed tomographic (CECT) imaging of the head and body. Intravascularly injected causes opacification of vessels, allowing for radiographic visualization of internal structures until significant hemodilution occurs.
T40861	Nerindocianine
	Nerindocianine is a hydrophilic, fluorescent diagnostic contrast agent that is predominantly metabolized by the kidneys, enabling non-invasive, intraoperative ureteral imaging.
T29592	Acetrizoate sodium Reopak,Diaginol,MP1023,MP 1023,MP-1023
	Acetrizoate sodium 又称醋碘苯酸的钠盐，可用作高渗透压、水溶性、碘化的放射造影剂。
T11629	Ifenprodil glucuronide	Others	Others
	Ifenprodil glucuronide, a derivative of Ifenprodil, is a vasodilator and an inhibitor of platelet aggregation. In contrast to Ifenprodil, Ifenprodil glucuronide does not affect platelet aggregation nor arterial contraction.
T38783	DOTA-tri(t-butyl ester)
	DOTA-tri(t-butyl ester) is a versatile compound employed for the synthesis of third-generation (G3) nanoglobular magnetic resonance imaging (MRI) contrast agents. These contrast agents find application in the fields of MR angiography and tumor angiogenesis imaging.

化合物

Cat.No: T19376

Synonym: MP-328,碘佛醇

Target: Others

Cat.No: T8406

Synonym: ZK 135079,钆布醇

Target: Others

Cat.No: T1554

Target: Mitophagy, Autophagy

Cat.No: T16471

Synonym: Perfluorooctyl bromide,全氟溴辛烷,PFOB

Target: Others

Gadopentetic acid

Cat.No: T19332

Synonym: gadolinium complex,钆喷酸,Gd-DTPA

Target: Others

Cat.No: T1576

Synonym: SQ-13396,Niopam,Iopamiron,Iopamiro,碘帕醇,B-15000,Isovue

Target: Others

Ioxitalamic Acid

Cat.No: T19799

Synonym: 碘羟拉酸,Telebrix,Vasobrix,Acidum Joxitalamicum

Target: Others

Cat.No: T0960

Synonym: 碘番酸,Iodopanoic acid,Acidum iopanoicum

Target: Others

Cat.No: T1522

Synonym: 碘普罗胺,Iopromidum,Ultravist

Target: Others

Acetrizoic acid

Cat.No: T0803

Synonym: Urokon,醋碘苯酸,Opacaron,Acetrizoesaeure

Target: Others

Cat.No: T1196

Synonym: 碘克沙醇,Visipaque,Acupaque

Target: Others

Cat.No: T5161

Target: Others

Sodium diatrizoate

Cat.No: T1319

Synonym: Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,泛影酸钠,Diatrizoate sodium,amidotrizoate sodium,Triombrin

Target: Apoptosis, Others

Cat.No: T0271

Synonym: Iodipamic acid,胆影酸,Adipiodone

Target: Others

Cat.No: T31786

Synonym: Magnetic Black,Black Iron BM,Magnetic oxide,Black Gold F 89,11557 Black

Target: Others

Diatrizoate meglumine

Cat.No: T20637

Synonym: Reno,Renografin,Renovist,泛影葡胺,Hypaque,Renocal,Sinografin

Target: Others

Cat.No: T19333

Synonym: ProHance,SQ-32692,钆特醇,Gd-HP-DO3A

Target: Others

Cat.No: T0503

Synonym: Meglumin,Methylglucamin,葡甲胺,葡萄糖甲胺,Methylglucamine

Target: Others

Ethylene thiourea

Cat.No: T20110

Synonym: ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲

Target: Others

Diatrizoic Acid

Cat.No: T1395

Synonym: Diatrizoate,泛影酸,Amidotrizoic acid

Target: Apoptosis, Others

Cat.No: T1937

Synonym: Spautin 1

Target: Apoptosis, DUB, Autophagy

Proflavine Hemisulfate

Cat.No: T0438

Synonym: 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate,硫酸原黄素

Target: Others, Potassium Channel, DNA, Thrombin, Antibacterial, Autophagy

Gemcitabine elaidate hydrochloride

Cat.No: T15378L

Synonym: CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride

Target: Others

Gadopentetate dimeglumine

Cat.No: T4506

Synonym: Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,钆喷酸葡胺,Gadopentetic acid dimeglumine salt

Target: Others

Gadoxetate Disodium

Cat.No: T15367

Synonym: Gd-EOB-DTPA Disodium,钆塞酸二钠,ZK 139834

Target: Others

Cat.No: T20870

Synonym: IR 820,IR820,New Indocyanine Green

Cat.No: T19375

Synonym: Iothalamic acid,碘他拉酸

Target: Others

Cat.No: T35133

Synonym: WIN 68056

Cat.No: T33369

Synonym: Amipak,Amipaque

Sodium Ioxaglate

Cat.No: T28826

Synonym: P-286,MP 302,MP-302,Ioxaglic acid,P 286

Cat.No: T34699

Synonym: S 043,S043,S-043

Cat.No: T16067

Synonym: 甲泛影酸,Metrizoate

Target: Others

Cat.No: T32182

Synonym: NSC 135284,NSC135284,NSC-135284,Hytrast,Iopydonum

Nebentan potassium

Cat.No: T36008

Cat.No: T20132

Synonym: 全氟己烷,Fluorinert FC72

Target: Others

Cat.No: T32183

Synonym: MP-3047-04,ICJ 3393,ICJ-3393,BP-13

Mangafodipir trisodium

Cat.No: T19413

Target: Others

Methiodal sodium

Cat.No: T33322

Synonym: Abrodan,Abrodil,Diagnorenol,Conturex,Iodomethanesulfonic acid sodium salt,Abroden

Cat.No: T33853

Synonym: P569,P-569

Cat.No: T32167

Synonym: BRN 2175358,Iodamidum,Ametriiodic acid

Cat.No: T32177

Synonym: GE-145,GE145,AN 113111,AN113111,AN-113111,GE 145

Cat.No: T31507

Synonym: Iodopyracet

Cat.No: T32867

S-2-(4-aminobenzyl)-diethylenetriamine penta-t-butyl acetate

Cat.No: TNU0613

Cat.No: T32178

Synonym: MP 8000,MP-8000

Cat.No: T19377

Target: Others

Cat.No: T40861

Acetrizoate sodium

Cat.No: T29592

Synonym: Reopak,Diaginol,MP1023,MP 1023,MP-1023

Ifenprodil glucuronide

Cat.No: T11629

Target: Others

DOTA-tri(t-butyl ester)

Cat.No: T38783

Cat. No.	Product Name	Target	Signaling Pathways
T5803	D(-)-Tartaric acid	Others	Others
	D(-)-Tartaric acid 存在于许多植物中，特别是罗望子和葡萄，口服后通过与碳酸氢钠相互作用产生二氧化碳。二氧化碳会延伸胃部并在双造影射线照相期间提供负造影剂。
TJS1183	Cyclen 轮环藤宁,1,4,7,10-tetraazacyclododecane	Others	Others
	Cyclen (1,4,7,10-tetraazacyclododecane) 是一种氮杂冠醚的类似物，是制备有效的大环螯合物的中间体，是制备磁共振造影剂的前体物质。
TN4427	Lethedioside A	Others	Others
	Lethedoside A was either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.

天然产物

D(-)-Tartaric acid

Cat.No: T5803

Target: Others

Cat.No: TJS1183

Synonym: 轮环藤宁,1,4,7,10-tetraazacyclododecane

Target: Others

Cat.No: TN4427

Target: Others

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