Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ioversol (MP-328) 是一种非离子碘化造影剂 (CM),不损伤动物的血脑屏障 (BBB),可用于动物实验的 CT 扫描或 x-ray。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 137 | 现货 | ||
5 mg | ¥ 289 | 现货 | ||
10 mg | ¥ 479 | 现货 | ||
25 mg | ¥ 691 | 现货 | ||
50 mg | ¥ 953 | 现货 | ||
100 mg | ¥ 1,320 | 现货 | ||
500 mg | ¥ 3,330 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 528 | 现货 |
产品描述 | Ioversol (MP-328) is a nonionic iodinated contrast agent. |
体外活性 | Ioversol significantly increases apoptosis and caspase-3 protein expression in the NRK-52E cells exposed to ioversol for 4 h. Ioversol treatment induces a significant increase in [Ca2+]i and intracellular ROS.Ioversol (100 mg iodine/ml) exposure induces significantly increased lactate dehydrogenase release and decreased 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl tetrazolium bromide conversion in NRK-52E cells. |
体内活性 | In comparison with iothalamate, ioversol has a greatly reduced propensity to stimulate the release of endothelin, from cultured cells and when injected into anesthetized rats. Ioversol produces less renal vasoconstriction than does iothalamate, in control and in USIC rats, and the development of radiocontrast nephropathy, assessed by creatinine clearance and morphologic damage to the renal medulla, is largely avoided. |
别名 | MP-328, 碘佛醇 |
分子量 | 807.11 |
分子式 | C18H24I3N3O9 |
CAS No. | 87771-40-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (61.95 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 1.239 mL | 6.1949 mL | 12.3899 mL | 30.9747 mL |
5 mM | 0.2478 mL | 1.239 mL | 2.478 mL | 6.1949 mL | |
10 mM | 0.1239 mL | 0.6195 mL | 1.239 mL | 3.0975 mL | |
20 mM | 0.0619 mL | 0.3097 mL | 0.6195 mL | 1.5487 mL | |
50 mM | 0.0248 mL | 0.1239 mL | 0.2478 mL | 0.6195 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Ioversol 87771-40-2 Others MP 328 medium MP-328 scan contrast Inhibitor x-ray inhibit 碘佛醇 MP328 inhibitor