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Search Results for " antileukemic activity "

9

抑制剂 & 化合物

11

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T24269	KPT-251 KPT251	Others	Others
	KPT-251 是一种选择性核输出抑制剂。
T25503	Hisphen Synonyms Hisfen,MD 2
	Hisphen shows antileukemic activity.
T24492	Moflomycin F 860191,F-860191,F860191
	Moflomycin is an anthracycline derivative. It exhibits a higher antileukemic activity compared to other anthracyclines.
T22132	PD 166326
	PD166326 是一种吡啶并嘧啶型受体酪氨酸激酶抑制剂，对于Src 和Abl 的IC50值分别为 6 nM 和 8 nM。PD166326 显示出抗白血病活性。
T15472	Hepsulfam NCI 329680,ZINC01574758	Others	Others
	Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors).
T25170	Botryodiplodin Cytostipin,Antibiotic PSX 1
	Botryodiplodin, an antibiotic, has antileukemic activity from Botryodiplodia theobromae. It has the property of turning the skin of the individual in various shades of pink 2-3 hrs after application. It is a toxic metabolite of Penicillium carneo-lutescen
T60559	S-(N-PhenethylthiocarbaMoyl)-L-cysteine
	S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) 是一种抗癌剂。S-(N-PhenethylthiocarbaMoyl)-L-cysteine 具有抗白血病活性，可抑制 HL60 细胞中的 DNA 合成。S-(N-PhenethylthiocarbaMoyl)-L-cysteine 是P450的抑制剂。
T73167	HDAC-IN-49
	HDAC-IN-49 是一种有效的非选择性 HDAC(HDAC) 抑制剂，对 HDAC1、HDAC2、HDAC3、HDAC4 和 HDAC6的 IC50分别为 13 nM、14 nM、21 nM、1880 nM 和 10 nM 。HDAC-IN-49 表现出显着的抗白血病活性，但对健康细胞具有低细胞毒性。
T82774	Caspase-3 activator 3	Caspase	Apoptosis; Proteases/Proteasome
	Caspase-3 activator 3 (compound 2h) 通过激活caspase 3诱导HL-60和K562细胞apoptosis，表现出抗白血病活性。其对HL-60细胞的IC50值为42.89 μM，对K562细胞的IC50值为33.61 μM。

化合物

Cat.No: T24269

Synonym: KPT251

Target: Others

Cat.No: T25503

Synonym: Synonyms Hisfen,MD 2

Cat.No: T24492

Synonym: F 860191,F-860191,F860191

Cat.No: T22132

Cat.No: T15472

Synonym: NCI 329680,ZINC01574758

Target: Others

Cat.No: T25170

Synonym: Cytostipin,Antibiotic PSX 1

S-(N-PhenethylthiocarbaMoyl)-L-cysteine

Cat.No: T60559

Cat.No: T73167

Caspase-3 activator 3

Cat.No: T82774

Target: Caspase

Cat. No.	Product Name	Target	Signaling Pathways
TN1932	Microhelenin C	Others	Others
	Microhelenin C 是抑制从Helenium microcephalum 中提取的倍半萜内酯，具有抗肿瘤作用。
TN4673	(+)-Nortrachelogenin Wikstromol,荛花酚	Apoptosis; HIV Protease; PI3K; Antifection	Apoptosis; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	(+)-Nortrachelogenin 是一种从 Wikstroemia indica C.A. Meyer （百里香科）中分离出来的木脂素。 (+)-Nortrachelogenin 具有抗白血病活性。
T5S1058	Triptonide 雷公藤内酯酮,PG 492,NSC 165677	Apoptosis; Wnt/beta-catenin; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Stem Cells
	Triptonide (PG 492) 是从雷公藤中鉴定出的一种天然产物，是一种 Wnt 信号抑制剂，其 IC50约为 0.3 nM。它具有免疫抑制、抗炎、避育、神经保护和抗淋巴瘤作用。
TN2319	Yadanzioside A 鸦胆子苷A,鸦胆子内脂A	Others	Others
	Yadanzioside A has antileukemic activity.
TN5266	Yadanzioside F	Others	Others
	Yadanzioside F has antileukemic activity.
TN5265	Yadanzioside C	Others	Others
	Yadanzioside C has antileukemic activity.
TN2320	Yadanzioside G	Others	Others
	Yadanzioside G has antileukemic activity.
TN4027	Eucannabinolide	Others	Others
	Eucannabinolide exhibits in vivo antileukemic activity.
TN3796	Dehydrobruceantinol	Others	Others
	Dehydrobruceantinol shows bitter taste and has antileukemic activity.
TN3542	Bruceantinoside A	Others	Others
	Bruceantinoside A has antileukemic activity.
TN5092	Tagitinin F	Antifection	Microbiology/Virology
	Tagitinin F possesses antileukemic activity; it also shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes.

天然产物

Cat.No: TN1932

Target: Others

(+)-Nortrachelogenin

Cat.No: TN4673

Synonym: Wikstromol,荛花酚

Target: Apoptosis, HIV Protease, PI3K, Antifection

Cat.No: T5S1058

Synonym: 雷公藤内酯酮,PG 492,NSC 165677

Target: Apoptosis, Wnt/beta-catenin, Autophagy

Cat.No: TN2319

Synonym: 鸦胆子苷A,鸦胆子内脂A

Target: Others

Cat.No: TN5266

Target: Others

Cat.No: TN5265

Target: Others

Cat.No: TN2320

Target: Others

Eucannabinolide

Cat.No: TN4027

Target: Others

Dehydrobruceantinol

Cat.No: TN3796

Target: Others

Bruceantinoside A

Cat.No: TN3542

Target: Others

Cat.No: TN5092

Target: Antifection

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