首页工具

登录

搜索结果

Search Results for " allergy "

15

抑制剂 & 化合物

6

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T26253	Tecastemizole Norastemizole,R-43512,R43512,R 43512,T 1348	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Tecastemizole (R 43512) 是 H1 受体的选择性拮抗剂，是阿司咪唑的主要代谢产物，具有抗炎作用。
T21419	Diphenhydramine 苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Diphenhydramine (Syntedril) 是第一代具有抗胆碱能作用的H1 受体拮抗剂，它能透过血脑屏障。
T15259	Evatanepag CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Evatanepag (CP-533536 free acid) 是一种 EP2 受体选择性前列腺素 E2 (PGE2) 激动剂，可诱导局部骨形成，EC50 为 0.3 nM。它在大鼠骨折愈合模型中以单剂量局部给药时表现出愈合骨折的能力。
T21390	Fexofenadine Carboxyterfenadine,Telfast,非索非那定,MDL 16.455,Allegra	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Fexofenadine (Carboxyterfenadine) 是一种抗组胺药物，用于治疗过敏症状，如鼻塞、花粉热和荨麻疹。与第一代抗组胺药相比，它通过血脑屏障并引起镇静的能力较差。
T3520	Setipiprant KYTH-105,塞替匹仑,ACT-129968	GPR; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
	Setipiprant (ACT-129968) 是一种口服的选择性 CRTH2 拮抗剂，IC50为6.0 nM。
T7084	2-Bromo-4'-hydroxyacetophenone SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮	Phosphatase	Metabolism
	2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) 是一种PTP1B 的有效抑制剂，其Ki=42 μM。
T24771	SCH-336 SCH336,SCH 336	Cannabinoid Receptor	GPCR/G Protein
	SCH-336是一种 CB2受体激动剂(Ki-1.8 nM, EC50-2 nM)，具有有效性，选择性和口服活性。SCH-336对 CB1受体也具有生物活性，对CB2受体的选择性是CB1的100倍。SCH-336能够减少鸟苷5'-3- o -(硫)三磷酸与含hCB 的膜的结合，抑制 BaF3/CB2 细胞迁移，抑制小鼠延迟型超敏反应模型中的白细胞迁移，抑制小鼠过敏模型中抗原诱导的肺嗜酸性粒细胞增多。
T28372	PF-06462894 PF 6462894,PF-6462894,PF6462894
	PF-06462894 is a morpholinopyrimidone mGlu5 (mGlu5 Ki = 6 nM) with favorable properties. PF-06462894 did not show any evidence of immune activation in a mouse drug allergy model.
T71053	AHR-5333 mandelate
	AHR-5333 mandelate is an anti-allergy compound which has been shown to protect against antigen-induced anaphylactic collapse and ascaris antigen-induced skin hypersensitivity. AHR-5333 mandelate has also been shown to inhibit 5-HETE, LTB4 and LTC4 synthesis.
T29545	Acamelin
	Acamelin is a quinone isolated from the Australian black wood acacia melanoxylon. It is responsible for the allergy-inducing properties of the species.
T26447	A 78773 A78773,A-78773
	A 78773 is a potent, selective, direct, and reversible 5-lipoxygenase inhibitor. It has activity in a variety of purified cells and in more complex biological systems such as whole blood, lung fragments, and tracheal tissues. A 78773 acts against inflamma
TQ0032L	Rosiptor acetate AQX-1125,AQX 1125,AQX1125,AQX-1125 acetate
	Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte
T81590	OVA peptide
	OVA peptide，主要源于鸡蛋清，作为I类MHC（主要组织相容性复合体）分子H-2Kb（小鼠MHC的I类基因）所呈递的特定卵白蛋白Kb限制性表位。在过敏性研究领域，OVA peptide具有广泛应用。
T78641	ER-27319	Syk	Angiogenesis; Tyrosine Kinase/Adaptors
	ER-27319为吖啶酮衍生物，高效选择性抑制SYK，阻断其酪氨酸磷酸化和活性。本化合物阻止抗原刺激下人及大鼠肥大细胞释放过敏介质，IC50约为10 μM，适用于过敏性疾病研究。
T37604	ITK inhibitor
	Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for the treatment of inflammation and immune-mediated disorders. ITK inhibitor (N-[5-[[3-[(4-Acetylpiperazin-1-yl)carbonyl]-4-methyl-6-methoxy-phenyl]thio]thiazol-2-yl]-4-(N-1,2-dimethylpropylaminome...

化合物

Cat.No: T26253

Synonym: Norastemizole,R-43512,R43512,R 43512,T 1348

Target: Histamine Receptor

Diphenhydramine

Cat.No: T21419

Synonym: 苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255

Target: Histamine Receptor

Cat.No: T15259

Synonym: CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸

Target: Prostaglandin Receptor

Cat.No: T21390

Synonym: Carboxyterfenadine,Telfast,非索非那定,MDL 16.455,Allegra

Target: Histamine Receptor

Cat.No: T3520

Synonym: KYTH-105,塞替匹仑,ACT-129968

Target: GPR, Prostaglandin Receptor

2-Bromo-4'-hydroxyacetophenone

Cat.No: T7084

Synonym: SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮

Target: Phosphatase

Cat.No: T24771

Synonym: SCH336,SCH 336

Target: Cannabinoid Receptor

Cat.No: T28372

Synonym: PF 6462894,PF-6462894,PF6462894

AHR-5333 mandelate

Cat.No: T71053

Cat.No: T29545

Cat.No: T26447

Synonym: A78773,A-78773

Rosiptor acetate

Cat.No: TQ0032L

Synonym: AQX-1125,AQX 1125,AQX1125,AQX-1125 acetate

Cat.No: T81590

Cat.No: T78641

Target: Syk

Cat.No: T37604

Cat. No.	Product Name	Target	Signaling Pathways
TN2290	Uvaol	Endogenous Metabolite; JNK; PPAR	DNA Damage/DNA Repair; MAPK; Metabolism
	Uvaol 存在于橄榄和初榨橄榄油中，具有抗炎、抗增殖和血管舒张活性。
T3S1534	Secoxyloganin 断氧化马钱苷,幼枝含断氧化马钱子甙,金银花	Anti-infection	Microbiology/Virology
	Secoxyloganin 是从Lonicera japonicaThunb 提取得到，能够抑制血流量减少，具有抗过敏活性。
T8297	Gomisin N	Apoptosis	Apoptosis
	Gomisin N 是从五味子中分离得到的一种天然产物，有镇静和催眠生物活性。它具有用于治疗过敏和抑制癌症增殖和诱导细胞凋亡的潜力。
TN3000	4,2'-Dihydroxy-4'-methoxychalcone	Others	Others
	4,2'-Dihydroxy-4'-methoxychalcone shows allergy-preventive effects.
T80019	17-Hydroxyneomatrine
	17-Hydroxyneomatrine 是一种从苦参 (Sophora flavescens) 提取的化合物，有效抑制人宫颈癌Hela细胞生长，并展现抗菌、抗过敏、抗肿瘤、抗心律失常、消肿、利尿、免疫调节等多种生物活性。
TN2517	1,7-Dihydroxy-2,3-dimethoxyxanthone	Others	Others
	1,7-Dihydroxy-2,3-dimethoxyxanthone may have medicinal use in the management of inflammation, asthma and allergy, it antagonises in a non competitive but, reversible manner the contractions induced by chemical inflammatory mediators in the guinea pig trac

天然产物

Cat.No: TN2290

Target: Endogenous Metabolite, JNK, PPAR

Cat.No: T3S1534

Synonym: 断氧化马钱苷,幼枝含断氧化马钱子甙,金银花

Target: Anti-infection

Cat.No: T8297

Target: Apoptosis

4,2'-Dihydroxy-4'-methoxychalcone

Cat.No: TN3000

Target: Others

17-Hydroxyneomatrine

Cat.No: T80019

1,7-Dihydroxy-2,3-dimethoxyxanthone

Cat.No: TN2517

Target: Others

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼