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Search Results for " udp "

62

抑制剂 & 化合物

19

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19595	UDP-glucuronic acid trisodium 尿苷二磷酸葡萄糖醛酸三钠,UDP-glucuronic acid trisodium,尿苷二磷酸葡糖醛酸	Others	Others
	UDP-glucuronic acid trisodium (UDP-glucuronic acid trisodium) 是各种生物领域中重要糖基结合物的必不可少的前体。这些糖基结合物包括哺乳动物的糖胺聚糖、植物细胞壁多糖和细菌囊聚糖基甘油脂。
T19596	UDP-GlcNAc Disodium Salt Uridine 5′-diphospho-N-acetylglucosamine,5′-二磷酸尿嘧啶核苷-N-乙酰半乳糖胺二钠盐,UDP-α-D-N-Acetylglucosamine Disodium Salt	Others	Others
	UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) 是一种 O-GlcNAc 转移酶 (OGT) 的供体底物。
T9369L	UDP-a-D-Galactose disodium salt	Others	Others
	UDP-a-D-Galactose disodium salt 是半乳糖基转移酶的供体底物，用于含半乳糖的寡糖的生物合成。
T37899	UDP-β-D-Glucose (sodium salt)
	UDP-β-D-Glucose is the stereoisomer of UDP-α-D-glucose (sodium salt) . The activities of the UDP-β-D-glucose isomer are not known.
T37898	UDP-α-D-Glucose (sodium salt hydrate)
	UDP-α-D-Glucose is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It has been shown to bind the P2Y14receptor (EC50= 0.35 μM), an atypical P2Y receptor involved in the activation of dendritic cells and glial cells.1It can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.2 1.Jacobson, K.A., Ivanov, A.A., de Castro, S., et al.Development of selective agonists and antagonists of P2Y receptorsPurin...
T37900	UDP-Glucuronic Acid (sodium salt hydrate)
	UDP-Glucuronic acid is a nucleoside diphosphate sugar that is a source of glucuronic acid for polysaccharide biosynthesis. This compound can be used for the formation of many glucuronides with various aglycones.1 1.Green, M.D., and Tephly, T.R.Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteinsDrug Metab. Dispos.26(9)860-867(1998)
T22525	5-OMe-UDP trisodium salt	Others	Others
	Potent P2Y6 agonist
T37901	UDP-N-acetyl-D-Glucosamine (sodium salt hydrate)
	UDP-N-acetyl-D-Glucosamine is a natural nucleotide sugar that is used by glycosyltransferases to transfer N-acetyl-D-glucosamine residues to substrates.1It is an important component of antibiotic biosynthesis pathways in fungi and lipopolysaccharide production in bacteria.2,3 1.Roseman, S.Reflections on glycobiologyJ. Biol. Chem.276(45)41527-41542(2001) 2.Kudo, F., and Eguchi, T.Biosynthetic genes for aminoglycoside antibioticsJ. Antibiot. (Tokyo)62(9)471-481(2009) 3.Mulrooney, E.F., Poon, K.K.,...
T74160	UDP-glucosamine disodium
	UDP-glucosamine (UDP-GlcNAc) disodium 是一种化合物，作为O-GlcNAc转移酶的底物，负责催化O-GlcNAc与蛋白质的结合。同时，O-GlcNAc酶则负责催化从蛋白质中移除O-GlcNAc。作为己糖胺生物合成途径的终产物，UDP-glucosamine (UDP-GlcNAc) disodium主要受葡萄糖-6-磷酸-谷氨酰胺:果糖-6-磷酸氨基转移酶(GFAT)的调节。
T75579	UDP-xylose disodium
	UDP-xylose disodium为从Cryptococcus laurentii (N RRL Y-1401)中提取的天然产物，属于核苷酸糖代谢过程中的一种代谢产物。
T73809	UDP-GalNAc disodium
	UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium 是一种糖核苷酸，同时为EpsC115底物，其中EpsC115为exopolymeric substance (EPS) N端残基1-115缺失的突变体。此化合物充当多种N-乙酰半乳糖胺基转移酶的供体底物，这些酶专门负责将GalNAc从核苷酸糖转移至特定的糖或肽受体上。
T75398	UDP-sugar pyrophosphorylase (BlUSP)
	UDP-sugar pyrophosphorylase (BlUSP) 是一种酶，其功能是将葡萄糖-1-磷酸(Glc-1-P)转化为UDP-葡萄糖(UDP-Glc)。该酶通过催化UTP的尿苷基到糖-1-磷酸的可逆转移，进而产生UDP-糖和焦磷酸(PPi)。
T83803	UDP-β-S sodium Uridine-5' O-(2-thiodiphosphate)
	UDP-β-S是一种针对嘌呤P2Y6受体的激动剂。它在表达P2Y6受体的1321N1细胞中，以选择性的方式诱导肌醇磷酸的累积（EC50 = 28 nM），相较于表达P2Y1、P2Y2或P2Y4受体的细胞，在10 µM时效果更显著。在1 µM浓度下，UDP-β-S诱导分离的大鼠主动脉平滑肌细胞的DNA合成。
T83839	Uridine 5'-methylenediphosphate sodium α,β-methylene UDP,UMP-CP
	Uridine 5’-methylenediphosphate (UMP-CP) 是 purinergic P2Y14 受体的激动剂，同时也是 UDP 的一种水解稳定衍生物。它在表达人类 P2Y14 的细胞中选择性地抑制 cAMP 产生，相较于表达人类 P2Y6 的细胞（EC50s 分别为 11 和 339 nM）。
T9054	RO6889678	HBV	Microbiology/Virology
	RO6889678 是高效的 HBV 衣壳结构抑制剂，其吸收、分布、代谢和排泄特征较为复杂。它可通过 CYP3A4 介导的氧化作用进行代谢，以及通过 UDP-葡萄糖醛酸基转移酶 UGT1A3 和 UGT1A1 介导的直接葡萄糖醛酸化作用进行代谢。它是一种诱导剂，可作用于人肝细胞中 CYP3A4 和共调节蛋白。
T10851	CMP-Sialic acid sodium salt CMP-Neu5Ac sodium salt	Others	Others
	CMP-Sialic acid sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. It provides a substrate for Golgi sialyltransferases. UDP-GlcNAc 2-epimerase initiates sialic acid synthesis.
T11876	LpxH-IN-AZ1	Antibacterial	Microbiology/Virology
	LpxH-IN-AZ1 是一种有效的 UDP-2,3-二酰基葡糖胺焦磷酸水解酶LpxH 抑制剂，也是磺酰基哌嗪化合物。LpxH-IN-AZ1 具有抗菌活性，对肺炎克雷伯菌具有抑制作用，IC50 为 0.36 μM。
T65012	Bis(4-nitrophenyl) phosphate BNPP	Others	Others
	Bis(4-nitrophenyl) phosphate （BNPP) 抑制UDP-半乳糖，可用于研究糖基转移酶膜拓扑结构。
T41275	PF-04753299	Others	Others
	PF-04753299 是一种有效的、选择性的LpxC 抑制剂。PF-04753299 对淋球菌分离株具有杀菌作用，对大肠杆菌、铜绿假单胞菌和肺炎菌株的抑制的MIC90值分别为 2 μg/ml、4 μg/ml 和 16 μg/ml。PF-04753299 用于革兰氏阴性菌感染的研究。
T73899	Uridine diphosphate glucuronic acid ammonium
	Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium 是一种由 UDP-葡萄糖脱氢酶催化生成的辅助因子，属于糖核苷酸生物合成的关键前体。它不仅是 C4 表聚酶和脱羧酶释放 UDP-半乳糖醛酸(UDP-GalA)和 UDP-戊糖产物的共同底物，而且作为葡萄糖醛酸供体，在胆红素在内质直肠结合的研究中有重要应用。
T68827	MRS2690
	MRS2690 is a potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
T38489	D,L-erythro-PDMP
	D,L-erythro-PDMP, an erythro isomer of PDMP, exhibits growth inhibition on cultured rabbit skin fibroblasts. Additionally, this compound serves as an effective inhibitor of UDP-glucose: ceramide glucosyltransferase.
T75399	GlcNAc 1-P uridyltransferase (CjGlmU)
	GlcNAc 1-P uridyltransferase (CjGlmU) 为一种糖核苷酸转移酶，以UTP和GlcNAc-1-P为天然底物，负责合成UDP-GlcNAc。此酶展现出潜在的抗菌活性分子研究价值。
T36826	Acetaminophen Glucuronide (sodium salt)
	Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen . It is formed via glucuronidation of acetaminophen by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A6, UGT1A9, UGT1A1, and UGT2B15.
T75413	beta-1,4-Galactosyltransferase (LgtB)
	beta-1,4-Galactosyltransferase (LgtB) (B4GALT1 (LgtB)) 通常用于生化研究。beta-1,4-Galactosyltransferase (LgtB) 催化涉及 UDP-半乳糖和 N-乙酰葡糖胺的反应，用于生产半乳糖 β-1,4-N-乙酰葡糖胺。
T61998	UGM-IN-3
	UGM-IN-3 (compound 10a) 是一种 UDP-吡喃半乳糖变位酶 (UGM) 抑制剂，Kd 为 66 μM。UGM-IN-3 抑制结核分枝杆菌的生长，MIC 值为 6.2 μg/mL。
T75397	Hyaluronan synthase (PmHAS)
	Hyaluronan synthase (PmHAS)为膜蛋白，依赖Mg+2及两种糖-UDP底物（GlcUA-UDP与GlcNAc-UDP）合成HA链。该酶负责透明质酸(HA)的生物合成。
T36300	Uridine-5’-monophosphate (sodium salt hydrate)
	Uridine-5’-monophosphate (UMP) is a ribonucleotide.1It is formedviadecarboxylation of orotidine-5’-monophosphate (5’-OMP) by OMP decarboxylase. UMP is further phosphorylated by UMP-CMP kinase to form UDP and UTP during nucleic acid biosynthesis. Formulations containing UMP have been used as dietary supplements. 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide BiosynthesisBiochemistry(2002)
T19685	Faldaprevir BI-201335,BI201335,BI 201335
	Faldaprevir is an effective NS3/NS4A protease inhibitor potentially for the treatment of HCV infection. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1.
T37117	Etodolac Acyl Glucuronide
	Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A9, UGT1A10, and UGT2B7. 1.Kutsuno, Y., Itoh, T., Tukey, R.H., et al.Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 miceDrug Metab. Dispos.42(7)1146-1152(2014)
T71215	Faldaprevir sodium
	Faldaprevir sodium is a potent NS3/NS4A protease inhibitor potentially for the treatment of HCV infection. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1.
T11715	JH-LPH-28	Others	Others
	JH-LPH-28, a sulfonyl piperazine analog, is a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH, exhibiting exceptional antibiotic activity with a minimum inhibitory concentration (MIC) value of 0.83 μg/mL.
T75417	alpha-1,3-Galactosyltransferase (a1,3GalT)
	α-1,3-Galactosyltransferase (a1,3GalT) (GGTA1) 能够将UDP中的半乳糖 (Gal) 通过α1-3键转移到糖蛋白的N-乙酰乳糖胺 (Galβ1,4GlcNAc-R) 上。该酶主要参与合成α-半乳糖 (α-Gal) 表位，此种表位在大多数哺乳动物中普遍存在。
T72129	D,L-erythro-PDMP hydrochloride
	D,L-erythro-PDMP hydrochloride 是 PDMP 的赤型异构体。D,L-erythro-PDMP 诱导体外兔皮肤成纤维细胞的生长抑制。PDMP 是一种 UDP 葡萄糖神经酰胺葡萄糖基转移酶抑制剂。
T35952	all-trans Retinoyl β-D-Glucuronide
	all-trans Retinoyl β-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase (UGT) system. It is rapidly converted to all-trans retinoic acid following in vitro or in vivo administration.
T11716	JH-LPH-33	Others	Others
	JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. It exhibits remarkable antibiotic activity, reflected by a minimal inhibitory concentration (MIC) value of 0.66 μg/mL.
T75411	beta-1, 3-N-Acetylhexaminyltransferase (LgtA)
	Beta-1, 3-N-Acetylhexaminyltransferase (LgtA) 是一种糖基转移酶，在生化研究中常见。该酶主要催化作用为将 N-乙酰葡糖胺从 UDP-GlcNAc 转移到 N-乙酰乳糖胺和乳糖上。
T37852	Chlorzoxazone N-Glucuronide
	Chlorzoxazone N-glucuronide is a phase II metabolite of the skeletal muscle relaxant chlorzoxazone . Chlorzoxazone N-glucuronide is formed via glucuronidation of chlorzoxazone by the UDP-glucuronosyltransferase (UGT) isoform UGT1A9.
T37005	Estriol 3-β-D-Glucuronide (sodium salt)
	Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membranes with Kd values of 85 and 164 μM, respectively. It competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide and is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc).
T37484	1-Salicylate Glucuronide
	1-Salicylate glucuronide is a metabolite of salicylic acid and aspirin .1It is formed from salicylic acid primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A9 but also by a variety of other UGT isoforms and from aspirinviasalicylic acid as an intermediate. 1.Kuehl, G.E., Bigler, J., Potter, J.D., et al.Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomesDrug Metab. Dispos.34(2)199-202(2006)
T39478	L-threo-PPMP
	L-threo-PPMP is an inhibitor of GlcT, which is the UDP-Glc: Ceramide β1,1glucosyltransferase enzyme. It effectively inhibits glycosphingolipid biosynthesis, while also inducing apoptosis. These properties of L-threo-PPMP contribute to its notable anti-cancer activity.
T62624	LpxA-IN-1
	LpxA-IN-1 是一种新型的 UDP-N-乙酰氨基葡萄糖酰基转移酶 (LpxA)抑制剂（IC502 nM）。LpxA-IN-1 具有抑制 Pseudomonas aeruginosa（MIC 8 μg/mL）的活性。
T78352	N-acetylglucosamine-1-P uridyltransferase (AGX1) GlcNAc1pUT
	N-acetylglucosamine-1-P uridyltransferase (AGX1) (GlcNAc1pUT) 是具有双功能乙酰转移酶/尿苷转移酶活性的原核生物专有酶。该酶能结合GlcNAc-1-P与UTP，催化合成UDP-GlcNAc的尿苷酰转移反应。
T36071	Silodosin Glucuronide (sodium salt)
	Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to rats with an LD50 value of 0.347 mg/kg.
T83873	Dabigatran Acyl-β-D-Glucuronide TFA Dabigatran β-1-O-Acyl Glucuronide
	Dabigatran acyl-β-D-glucuronide是凝血酶抑制剂dabigatran的一种活性代谢产物，主要通过UDP-葡萄糖醛酸转移酶(UGT)的UGT2B15亚型形成。在人体去除血小板的贫血浆中，Dabigatran acyl-β-D-glucuronide (0.46 µM) 能增加活化部分凝血活酶时间(aPTT)。
T73747	CMP-Sialic acid
	CMP-Sialic acid (CMP-Neu5Ac) 是 UDP-GlcNAc 2-epimerase 的变构抑制剂。CMP-Sialic acid 可为高尔基体唾液酸转移酶提供底物。CMP-Sialic acid 是唾液酸及其结合物的生物合成中的重要糖类核苷酸。
T36081	Trehalose 6-phosphate (potassium salt hydrate)
	Trehalose is a natural non-reducing disaccharide found in plants, invertebrates, fungi, and bacteria.1,2In addition to roles as an energy source and stress protectant, trehalose can function as a signaling molecule.3,4Trehalose 6-phosphate is an intermediate in the biosynthesis of trehalose. It is generated from UDP-glucose and glucose 6-phosphate by trehalose 6-phosphate synthase (TPS or otsA).5In plants, changes in trehalose 6-phosphate levels positively correlate with diurnal changes in sucro...
T75418	alpha-1,3-Galactosyltransferase (GTB)
	Alpha-1,3-Galactosyltransferase (GTB) 催化异种抗原或 α-半乳糖 (α-Gal) 表位的合成，通过将 UDP-Gal 中的半乳糖转移到类型1或类型2的 αFuc1→2βGal-R (H)-终止受体上。
T35939	Dabigatran Acyl-β-D-Glucuronide
	Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabolized primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15 to form dabigatran acyl-β-D-glucuronide. Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran.
T35845	(R,S)-Carvedilol Glucuronide
	(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. (R)-Carvedilol glucuronide is formed via glucuronidation of (R)-carvedilol by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1 and UGT2B4. (S)-Carvedilol glucuronide is formed via glucuronidation of (S)-carvedilol by UGT2B4 and UGT2B7.

化合物

UDP-glucuronic acid trisodium

Cat.No: T19595

Synonym: 尿苷二磷酸葡萄糖醛酸三钠,UDP-glucuronic acid trisodium,尿苷二磷酸葡糖醛酸

Target: Others

UDP-GlcNAc Disodium Salt

Cat.No: T19596

Synonym: Uridine 5′-diphospho-N-acetylglucosamine,5′-二磷酸尿嘧啶核苷-N-乙酰半乳糖胺二钠盐,UDP-α-D-N-Acetylglucosamine Disodium Salt

Target: Others

UDP-a-D-Galactose disodium salt

Cat.No: T9369L

Target: Others

UDP-β-D-Glucose (sodium salt)

Cat.No: T37899

UDP-α-D-Glucose (sodium salt hydrate)

Cat.No: T37898

UDP-Glucuronic Acid (sodium salt hydrate)

Cat.No: T37900

5-OMe-UDP trisodium salt

Cat.No: T22525

Target: Others

UDP-N-acetyl-D-Glucosamine (sodium salt hydrate)

Cat.No: T37901

UDP-glucosamine disodium

Cat.No: T74160

UDP-xylose disodium

Cat.No: T75579

UDP-GalNAc disodium

Cat.No: T73809

UDP-sugar pyrophosphorylase (BlUSP)

Cat.No: T75398

UDP-β-S sodium

Cat.No: T83803

Synonym: Uridine-5' O-(2-thiodiphosphate)

Uridine 5'-methylenediphosphate sodium

Cat.No: T83839

Synonym: α,β-methylene UDP,UMP-CP

Cat.No: T9054

Target: HBV

CMP-Sialic acid sodium salt

Cat.No: T10851

Synonym: CMP-Neu5Ac sodium salt

Target: Others

Cat.No: T11876

Target: Antibacterial

Bis(4-nitrophenyl) phosphate

Cat.No: T65012

Synonym: BNPP

Target: Others

Cat.No: T41275

Target: Others

Uridine diphosphate glucuronic acid ammonium

Cat.No: T73899

Cat.No: T68827

D,L-erythro-PDMP

Cat.No: T38489

GlcNAc 1-P uridyltransferase (CjGlmU)

Cat.No: T75399

Acetaminophen Glucuronide (sodium salt)

Cat.No: T36826

beta-1,4-Galactosyltransferase (LgtB)

Cat.No: T75413

Cat.No: T61998

Hyaluronan synthase (PmHAS)

Cat.No: T75397

Uridine-5’-monophosphate (sodium salt hydrate)

Cat.No: T36300

Cat.No: T19685

Synonym: BI-201335,BI201335,BI 201335

Etodolac Acyl Glucuronide

Cat.No: T37117

Faldaprevir sodium

Cat.No: T71215

Cat.No: T11715

Target: Others

alpha-1,3-Galactosyltransferase (a1,3GalT)

Cat.No: T75417

D,L-erythro-PDMP hydrochloride

Cat.No: T72129

all-trans Retinoyl β-D-Glucuronide

Cat.No: T35952

Cat.No: T11716

Target: Others

beta-1, 3-N-Acetylhexaminyltransferase (LgtA)

Cat.No: T75411

Chlorzoxazone N-Glucuronide

Cat.No: T37852

Estriol 3-β-D-Glucuronide (sodium salt)

Cat.No: T37005

1-Salicylate Glucuronide

Cat.No: T37484

Cat.No: T39478

Cat.No: T62624

N-acetylglucosamine-1-P uridyltransferase (AGX1)

Cat.No: T78352

Synonym: GlcNAc1pUT

Silodosin Glucuronide (sodium salt)

Cat.No: T36071

Dabigatran Acyl-β-D-Glucuronide TFA

Cat.No: T83873

Synonym: Dabigatran β-1-O-Acyl Glucuronide

CMP-Sialic acid

Cat.No: T73747

Trehalose 6-phosphate (potassium salt hydrate)

Cat.No: T36081

alpha-1,3-Galactosyltransferase (GTB)

Cat.No: T75418

Dabigatran Acyl-β-D-Glucuronide

Cat.No: T35939

(R,S)-Carvedilol Glucuronide

Cat.No: T35845

Cat. No.	Product Name	Target	Signaling Pathways
T8949	UDP-g acid	Others	Others
	UDP-g acid 是一种用于生产多糖的糖，是抗坏血酸生物合成的中间体。
T75525	UDP-rhamnose UDP-L-rhamnose	Endogenous Metabolite	Metabolism
	UDP-rhamnose (UDP-L-rhamnose) 是一种广泛存在于动植物中的糖核苷酸，可用于合成细胞壁中果胶。UDP-rhamnose 可被真菌中识别，可用于合成槲皮素。
T80020	UDP-3-O-acyl-GlcNAc diammonium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Endogenous Metabolite	Metabolism
	UDP-3-O-acyl-GlcNAc diammonium 是一种E. coli代谢产物，涉及3-deoxy-D-manno-octulosonate (KDO) 生物合成途径。
T4743	Uridine 5′-diphosphoglucose disodium salt 二磷酸尿苷葡萄糖二钠盐,UDP-Glucose sodium salt,UDPG sodium salt,UDP-α-D-Glucose sodium salt,Uridine 5'-diphosphoglucose disodium sal	Endogenous Metabolite; P2Y Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) 是一种内源性核苷酸糖，参与代谢中的糖基转移酶反应。它是 P2Y14 受体的激动剂，EC50为 0.35 μM。
T4706	Uridine-5'-diphosphate disodium salt UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐	DNA/RNA Synthesis; Endogenous Metabolite; P2Y Receptor	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Uridine-5'-diphosphate disodium salt (UDP disodium salt) 是一种选择性 P2Y6受体激动剂，EC50为300 nM，对人 P2Y6受体的 pEC50为6.52。它可刺激炎症介质的产生、吞噬作用和血管收缩，催化多种底物的葡糖醛酸糖化反应，用于核酸生物合成。
T73607	UDP-xylose
	UDP-xylose是一种从Cryptococcus laurentii（NRRL Y-1401）提取的天然产物。它作为糖供体，在植物、脊椎动物和真菌中参与糖蛋白、多糖及多种代谢物和寡糖的合成。
T75685	UDP-3-O-acyl-GlcNAc
	UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) 是一种E. coli 代谢产物，参与 3-deoxy-D-manno-octulosonate (KDO) 生物合成途径。
T13229	Tunicamycin	Influenza Virus; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Tunicamycin 是一种抗生素的混合物，通过阻断 GlcNAc 磷酸转移酶 (GPT)，抑制 N-连接糖基化。Tunicamycin 具有抗肿瘤活性，还具有抗细菌、抗真菌和抗病毒活性。
T4878	Hecogenin 海柯吉宁,Hocogenin	Others; Antifungal	Microbiology/Virology; Others
	Hecogenin（Hocogenin），一种从Agave sisalana提取的甾体皂苷，作为人类UDP-glucuronosyltransferases的特异性抑制剂。它具有广泛的药理活性，包括抗炎、抗真菌和胃保护作用[1]。
TN1160	1,2,3,6-Tetragalloylglucose 1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG	LDL; UGT	Metabolism
	1,2,3,6-Tetragalloylglucose (TeGG) 是 UDP-葡萄糖醛酸转移酶 1 家族成员，是多肽A1 的抑制剂(Ki:1.68 μM)。
TJO2758	D-Glucuronic acid D-葡萄糖醛酸,Aldehydo-D-Glucuronic Acid	Others; Endogenous Metabolite	Metabolism; Others
	D-Glucuronic acid (Aldehydo-D-Glucuronic Acid) 是一种从许多树胶中分离出的重要中间体。它对皮肤具有抗炎作用。它及其衍生物葡萄糖醛酸内酯作为预防人类健康的肝脏解毒剂。
T0004	Salicylamide 水杨酰胺,Salamide,2-Hydroxybenzamide	COX	Immunology/Inflammation; Neuroscience
	Salicylamide(2-Hydroxybenzamide) 是一种止痛剂和抗热解药剂，是一种微粒体 UDP-葡糖醛酸基转移酶抑制剂。
T3600	Licochalcone A	Caspase; UGT; Autophagy	Apoptosis; Autophagy; Metabolism; Proteases/Proteasome
	Licochalcone A 是从名药甘草中分离得到的黄酮类天然产物，具有抗癌功效，对UDP-葡萄糖醛酸转移酶 (UGTs) 具有广泛抑制活性。它对 UGT1A1、1A3、1A4、1A6、1A7、1A9 和 2B7 具有强烈的抑制作用，IC50和Ki 值均低于5 μM。
TN1036	Gomisin D 戈米辛 D,戈米辛D	Others	Others
	Gomisin D 是一种分离自五味子中的木脂素。它抑制 UDP-葡糖醛酸基转移酶活性，清除 ABTS(+) 自由基。它是生脉散和参芪降糖颗粒的质量标志物，具有成为抗糖尿病药和抗阿尔茨海默病药的潜力。
T4S0145	Corylifol A Corylinin,补骨脂异黄酮A	hCE; STAT; UGT	JAK/STAT signaling; Metabolism; Stem Cells
	Corylifol A (Corylinin) 是补骨脂中的一种天然产物，可抑制IL-6 诱导的STAT3激活和磷酸化，IC50值为0.81 μM。
T7995	α-Angelica lactone α-当归内酯,当归内酯,Alpha-Angelica Lactone	Others; GST	Others; oxidation-reduction
	α-Angelica lactone 是一种乙烯基亲核试剂，也是一种天然存在的抗癌剂。它可以得到手性的 δ-氨基 γ，γ-二取代丁烯醇内酯羰基衍生物，并在 γ-碳上表现出亲电子俘获。它通过选择性增强谷胱甘肽-S-硫转移酶 (GST) 和 UDP-葡糖苷转移酶 (UGT) 解毒酶发挥强大的化学保护作用。
T3S0860	Gitogenin	UGT	Metabolism
	Gitogenin 是一种从Tribulus longipetalus 整株中分离出来的天然类固醇，是一种 UDP-葡萄糖醛酸转移酶 1A4 (UGT1A4) 和 α-葡萄糖苷酶的选择性抑制剂，其IC50分别为 0.69 µM (使用三氟拉嗪为底物) 和 37.2 μM，对人类主要细胞色素 P450 亚型的活性无抑制作用。
TN5356	Epiglobulol
	Epiglobulol shows antibacterial activities, it can strongly inhibit the growth of foodborne microorganisms. Epiglobulol can inhibit the recombinant human UDP-glucuronosyltransferase (UGT) 2B7, it may serve as valuable lead structures for the design of pot
T10805	Cholesterol glucuronide	Others	Others
	Cholesterol glucuronide is an endogenous metabolite of lipid generated by UDP glucuonyltransferase in the liver.

天然产物

Cat.No: T8949

Target: Others

Cat.No: T75525

Synonym: UDP-L-rhamnose

Target: Endogenous Metabolite

UDP-3-O-acyl-GlcNAc diammonium

Cat.No: T80020

Synonym: UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium

Target: Endogenous Metabolite

Uridine 5′-diphosphoglucose disodium salt

Cat.No: T4743

Synonym: 二磷酸尿苷葡萄糖二钠盐,UDP-Glucose sodium salt,UDPG sodium salt,UDP-α-D-Glucose sodium salt,Uridine 5'-diphosphoglucose disodium sal

Target: Endogenous Metabolite, P2Y Receptor

Uridine-5'-diphosphate disodium salt

Cat.No: T4706

Synonym: UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐

Target: DNA/RNA Synthesis, Endogenous Metabolite, P2Y Receptor

Cat.No: T73607

UDP-3-O-acyl-GlcNAc

Cat.No: T75685

Cat.No: T13229

Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal

Cat.No: T4878

Synonym: 海柯吉宁,Hocogenin

Target: Others, Antifungal

1,2,3,6-Tetragalloylglucose

Cat.No: TN1160

Synonym: 1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG

Target: LDL, UGT

D-Glucuronic acid

Cat.No: TJO2758

Synonym: D-葡萄糖醛酸,Aldehydo-D-Glucuronic Acid

Target: Others, Endogenous Metabolite

Cat.No: T0004

Synonym: 水杨酰胺,Salamide,2-Hydroxybenzamide

Target: COX

Cat.No: T3600

Target: Caspase, UGT, Autophagy

Cat.No: TN1036

Synonym: 戈米辛 D,戈米辛D

Target: Others

Cat.No: T4S0145

Synonym: Corylinin,补骨脂异黄酮A

Target: hCE, STAT, UGT

α-Angelica lactone

Cat.No: T7995

Synonym: α-当归内酯,当归内酯,Alpha-Angelica Lactone

Target: Others, GST

Cat.No: T3S0860

Target: UGT

Cat.No: TN5356

Cholesterol glucuronide

Cat.No: T10805

Target: Others

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