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Targets Recommended: Opioid Receptor

3

抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T4411 DAMGO TFA (78123-71-4(Free base))

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
DAMGO TFA (78123-71-4(Free base)) 是Mu-opioid 受体的强效选择性激动剂。它也是镇痛药。它刺激钙激活的腺苷酸环化酶相关 cAMP 的产生。通过 TGF-beta1 表达趋化因子和趋化因子受体。增加老鼠的食物摄入量。
TP1607 DAMGO (TFA)

DAMGO is a selective peptide agonist of the µ-opioid receptor .
T4351 DAMGO

Dagol,DAGO,RX-783006

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
DAMGO (DAGO) 是一种阿片受体激动剂,Kd 值为 3.46 nM。它能够影响啮齿动物的运动活动,可作为镇痛剂。

化合物

DAMGO TFA (78123-71-4(Free base))
Cat.No: T4411
Synonym:
Target: Opioid Receptor
DAMGO (TFA)
Cat.No: TP1607
Synonym:
Target:
DAMGO
Cat.No: T4351
Synonym: Dagol,DAGO,RX-783006
Target: Opioid Receptor
Cat. No. Product Name Target Signaling Pathways
TN2165 Rubrofusarin gentiobioside

Rubrofusarin-6-O-beta-D-gentiobioside,红链霉素-龙胆二糖苷,芸苔红素龙胆苷

ERK; NF-κB; TGF-beta/Smad MAPK; NF-κB; Stem Cells
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) 一种分离自决明子的、具有清除自由基作用的化合物。
T3S1227 Aristolactam I

Aristolactam,Aristololactam I,马兜铃内酰胺I,Aristololactum

Apoptosis; Caspase Apoptosis; Proteases/Proteasome
Aristolactam I (Aristololactum) 是马兜铃酸 I (AA-I) 的主要代谢产物,参与导致肾损伤的过程。它具有细胞毒性,通过诱导半胱天冬酶 3 依赖性途径中的细胞凋亡介导。

天然产物

Rubrofusarin gentiobioside
Cat.No: TN2165
Synonym: Rubrofusarin-6-O-beta-D-gentiobioside,红链霉素-龙胆二糖苷,芸苔红素龙胆苷
Target: ERK, NF-κB, TGF-beta/Smad
Aristolactam I
Cat.No: T3S1227
Synonym: Aristolactam,Aristololactam I,马兜铃内酰胺I,Aristololactum
Target: Apoptosis, Caspase
Cat. No. Product Name Species Expression System
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His)

transforming growth factor, beta 1,TGF...

Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated

transforming growth factor, beta 1,transfo...

Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-01027 Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)

carnitine palmitoyltransferase 1B (muscle),AV080368...

Mouse HEK293 Cells
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. It is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. The granule-derived mouse mast cell proteases-1 and -2 (mMCP-1 and -2) colocalize in similar quantities in mucosal mast cells but micrograms of mMCP-1 compared w...

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Latent TGF beta 1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00500
Species: Mouse
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05313
Species: Mouse
Expression System: HEK293 Cells
Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01027
Species: Mouse
Expression System: HEK293 Cells
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