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Cat. No.	Product Name	Target	Signaling Pathways
T6009	TAPI1 TAPI 1,TAPI,TAPI-1	MMP	Proteases/Proteasome
	TAPI1 (TAPI) 是一种 ADAM17/TACE 抑制剂，可抑制细胞因子受体的脱落。
TQ0129	TNF Protease Inhibitor 2 TAPI-2	MMP	Proteases/Proteasome
	TAPI-2 is a broad-spectrum inhibitor of MMP (IC50: 20 μM), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM).
TP2107	TAPI 0
	ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.
TP2108	TAPI 2
	ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes.
T4122	TAPI-1 trifluoroacetate (163847-77-6(free base))	MMP	Proteases/Proteasome
	TAPI-1 trifluoroacetate 是一种 ADAM17/TACE 抑制剂，可阻断细胞因子受体的脱落。
T70664	TAPI-0
	TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.
T63390	(S,S)-TAPI-1
	(S,S)-TAPI-1 是一种 TAPI-1 的异构体。其中 TAPI-1是金属蛋白酶 (MMP) 抑制剂，也是 TACE(ADAM17) 抑制剂，对多种细胞表面蛋白脱落表现出有效的抑制作用。
T31992	Granotapide	CETP	Metabolism
	Granotapide 是一种微粒体甘油三酯转移蛋白（MTP）抑制剂，治疗和而预防动脉硬化，冠状动脉疾病，代谢综合征，肥胖，糖尿病，糖尿病前期和高血压。
T35316	Zometapine CI 716,Zolazepamum,CI-716,CI716,Flupyrazapon	Others	Others
	Zometapine (CI 716) 是一种抗抑郁化合物，是吡唑和二氮卓的衍生物。
T4223	Mitapivat PKR-IN-1	PKM	Metabolism
	Mitapivat (PKR-IN-1) 是口服具有活性的变构丙酮酸激酶 (pyruvate kinase) 激活剂，其AC50=20 nM。它在广泛的 PKLR 基因型中增加酶活性、蛋白质稳定性和 ATP 水平。它有潜在的恢复 PK 缺乏的糖酵解途径活性的作用。
T4644	Tapinarof GSK2894512,Benvitimod,苯烯莫德,WBI 1001	AhR; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism
	Tapinarof (Benvitimod) 是一种从发光杆菌中提取的天然产物，可消除炎症。它是芳烃受体 (AhR) 激动剂，EC50为 13 nM。
T2545	Lomitapide Mesylate 甲磺酸洛美他派,BMS-201038 mesylate,AEGR-733 mesylate	CETP	Metabolism
	Lomitapide Mesylate (BMS-201038 mesylate) 是一种高效MTP 蛋白抑制剂，其体外IC50值为8 nM。
T6267	Lomitapide AEGR-733,洛美他派,BMS-201038	CETP	Metabolism
	Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂，体内试验的IC50值为8 nM。
T15006	Dirlotapide CP742033,Slentrol	Others; CETP	Metabolism; Others
	Dirlotapide (CP742033) 是一种肠道选择性微粒体甘油三酯转移蛋白(MTP)抑制剂。它可以减轻糖尿病狗的体重。Dirlotapide 以剂量依赖性方式减少食物摄入量，可能是通过增加肽YY 释放到循环中。
T3179	Eptapirone F 11440	5-HT Receptor	GPCR/G Protein; Neuroscience
	Eptapirone (F 11440) 是一种高效且选择性的 5-HT1A 受体激动剂，具有显着的抗抑郁和抗焦虑潜力。
T35005	Usistapide R-256918,JNJ-16269110,JNJ16269110,R256918,JNJ 16269110,R 256918
	UsISpide(JNJ-16269110 R256918) is an inhibitor of microsomal triglyceride transfer protein (MTTP) under development for the treatment of obesity and type 2 diabetes.
T15570	Implitapide 英普他派,AEGR 427	CETP	Metabolism
	Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T10504	Implitapide Racemate	Others	Others
	Implitapide Racemate is the racemate of Implitapide. Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T69865	Mitapivat sulfate
	Mitapivat sulfate, also known as AG-348 sulfate hydrate, is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency.
T7459	Abametapir 5 5'-二甲基-2,2-联吡啶,HA-44,BRN 0123183	MMP; Others; Parasite	Microbiology/Virology; Others; Proteases/Proteasome
	Abametapir (BRN 0123183) 是一种金属蛋白酶抑制剂，能够靶向对卵孵化和虱子发育至关重要的金属蛋白酶。
T69677	Mitapivat sulfate anhydrous
	Mitapivat sulfate anhydrous is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency.
T73667	Motapizone
	Motapizone (NAT 05-239) 是一种选择性 PDE3抑制剂。Motapizone 适度抑制脂多糖 (LPS) 诱导的肺泡巨噬细胞中细胞因子的释放。Motapizone 还通过增加细胞内 cAMP 来抑制人血小板聚集。
T124572	Desacetylcentapicrin
	Desacetylcentapicrin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124572，CAS号为 60197-56-0。
T31801	Florbetapir F-18
	Florbetapir F-18 is a PET agent for Abeta plaques.
T70183	Eptapirone fumarate
	Eptapirone, also known as F11440, is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (pKi, 7.50), and somewhat lower than that of flesinoxan (pKi, 8.91). In vivo, F 11440 was 4- to 20-fold more potent than flesinoxan, and 30- to 60-fold more potent than buspirone, in exerting 5-HT1A agonist activity at pre- and postsynaptic receptors in rats (measured by, for exam...
T41082	Flobetapir AV-45,Flobetapir
	Flobetapir (AV-45) is a well-tolerated imaging compound used in PET scanning. It is synthesized to create Florbetapir (18F), which is a radiopharmaceutical compound containing fluorine-18 radionuclide.

化合物

Cat.No: T6009

Synonym: TAPI 1,TAPI,TAPI-1

Target: MMP

TNF Protease Inhibitor 2

Cat.No: TQ0129

Synonym: TAPI-2

Target: MMP

Cat.No: TP2107

Cat.No: TP2108

TAPI-1 trifluoroacetate (163847-77-6(free base))

Cat.No: T4122

Target: MMP

Cat.No: T70664

Cat.No: T63390

Cat.No: T31992

Target: CETP

Cat.No: T35316

Synonym: CI 716,Zolazepamum,CI-716,CI716,Flupyrazapon

Target: Others

Cat.No: T4223

Synonym: PKR-IN-1

Target: PKM

Cat.No: T4644

Synonym: GSK2894512,Benvitimod,苯烯莫德,WBI 1001

Target: AhR, Aryl Hydrocarbon Receptor

Lomitapide Mesylate

Cat.No: T2545

Synonym: 甲磺酸洛美他派,BMS-201038 mesylate,AEGR-733 mesylate

Target: CETP

Cat.No: T6267

Synonym: AEGR-733,洛美他派,BMS-201038

Target: CETP

Cat.No: T15006

Synonym: CP742033,Slentrol

Target: Others, CETP

Cat.No: T3179

Synonym: F 11440

Target: 5-HT Receptor

Cat.No: T35005

Synonym: R-256918,JNJ-16269110,JNJ16269110,R256918,JNJ 16269110,R 256918

Cat.No: T15570

Synonym: 英普他派,AEGR 427

Target: CETP

Implitapide Racemate

Cat.No: T10504

Target: Others

Mitapivat sulfate

Cat.No: T69865

Cat.No: T7459

Synonym: 5 5'-二甲基-2,2-联吡啶,HA-44,BRN 0123183

Target: MMP, Others, Parasite

Mitapivat sulfate anhydrous

Cat.No: T69677

Cat.No: T73667

Desacetylcentapicrin

Cat.No: T124572

Florbetapir F-18

Cat.No: T31801

Eptapirone fumarate

Cat.No: T70183

Cat.No: T41082

Synonym: AV-45,Flobetapir

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