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Search Results for " snap "

Targets Recommended: Others

24

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T23375	SNAP	Others	Others
	NO donor
T8004	SNAP 94847 hydrochloride	GPR; Melanin-concentrating Hormone Receptor (MCHR)	Endocrinology/Hormones; GPCR/G Protein
	SNAP 94847 hydrochloride 是一种选择性黑色素浓缩激素受体1 拮抗剂，Ki 为 2.2 nM，具有抗抑郁样活性。它是 MCH 诱发的肌醇磷酸形成的高亲和力拮抗剂，pA2为 7.81。
T28822	SNAP 398299 SNAP-398299,SNAP398299
	SNAP 398299, a galanin receptor antagonist, is a potential novel pharmacological treatment for mood disorders.
T5406	SNAP 94847 SNAP-94847	GPR; Melanin-concentrating Hormone Receptor (MCHR)	Endocrinology/Hormones; GPCR/G Protein
	SNAP 94847 (SNAP-94847) 是一种选择性黑色素浓缩激素受体1 拮抗剂，Ki 为 2.2 nM。它具有抗焦虑和抗抑郁活性，可减少小鼠的食物摄入。
T5455	HT-2157 SNAP37889,SNAP-37889	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	HT-2157 (SNAP-37889) 是一种高亲和力、选择性和竞争性的甘丙肽 3 受体 (Gal3) 拮抗剂。
T16831	(S)-SNAP5114	Others; GABA Receptor	Membrane transporter/Ion channel; Neuroscience; Others
	(S)-SNAP5114 是一种选择性的 GABA 转运抑制剂，对 hGAT-3 的 IC50 为 5 μM，对 rGAT-2 的 IC50 为 21 μM。 (S)-SNAP5114 具有抗惊厥性质。
T15688	L-771688 SNAP 6383	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-771688（SNAP 6383）是一种新型有效和选择性的 α1A-肾上腺素受体拮抗剂， Ki 值为 0.43±0.02 nM。L-771688 KE 用于治疗良性前列腺增生。
T70437	SNAP-5089
	SNAP-5089 is a highly selective alpha1A-adrenoceptor antagonist.
T28823	SNAP-7941 SNAP7941
	SNAP-7941 is a selective antagonist of the melanin concentrating hormone receptor MCH1 with promising anxiolytic, antidepressant and anorectic effects in initial animal studies.
T23374	SNAP 5089	Others	Others
	α1A-adrenoceptor antagonist
T34666	SNAP-8719 SNAP8719
	SNAP-8719 is a selective antagonist of α1D-AR. SNAP-8719 showed better selectivity for α1D-AR and lower binding affinity for the 5-HT1A receptor.
T12808	S-Nitroso-N-acetyl-DL-penicillamine N-乙酰基-3-(硫代亚硝基)-DL-缬氨酸,SNAP	NO Synthase	Immunology/Inflammation
	S-Nitroso-N-acetyl-DL-penicillamine (SNAP) 是一种稳定的血小板聚集抑制剂，是一氧化氮的供体。
T6990L	SNAP8 Acetate(868844-74-0,free base)	Others	Others
	SNAP8 Acetate(868844-74-0,free base) 减少皱纹出现。
T6990	SNAP8 Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2,SNAP 8,SNAP-8	Others	Others
	SNAP8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2) 是 SNAP-25 N 末端的模拟物，它与 SNAP-25 竞争 SNARE 复合物中的位置，从而调节其形成。
TP1576	SNAP-25 187-203
	This amino acids187 to 203 fragment is derived from the C-terminal helix of synaptosomal-associated protein of 25 kDa (SNAP-25). This peptide is able to rescue exocytosis from botulinum neurotoxin E (BoNT/E)-treated cells, albeit at higher concentrations
T39468	PYBG-TMR
	PYBG-TMR, a fluorochrome, serves as a dye that specifically and efficiently labels genetically encoded SNAP-tags in live cells.
T39469	PYBG-BODIPY
	PYBG-BODIPY, a fluorochrome dye, specifically and efficiently labels genetically encoded SNAP-tags in live cells, serving its role as a targeted marker.
T38538	BGN3
	BGN3 is a good substrate for the SNAP- tag and H 5 enzymes. The activities of SNAP- tag and H 5 enzymes on BGN3 are reasonable (IC 50 = 15.6 and 23.5 μM, respectively).
T39487	HaXS8
	HaXS8 is a dimerizer that facilitates the covalent and irreversible intracellular dimerization of proteins of interest labeled with HaloTag and SNAP-tag. Furthermore, HaXS8 does not exhibit any interference with PI3K/mTOR signaling.
T78396	Janelia Fluor® 646 TFA JF646 TFA
	Janelia Fluor® 646 TFA（JF646 TFA）是一种红色荧光染料，专用于Janelia Fluor 646 HaloTag和SNAP-Tag配体的合成，并适用于活细胞成像实验。
T39504	PA Janelia Fluor® 646, SE PA-JF646-NHS
	PA Janelia Fluor 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag and SNAP-tag . PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λ Excitation/emission ~650/664 nm).
T79925	T4 UvsX Recombinase	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	T4 UvsX Recombinase 促进双链DNA模板上DNA复制的启动，通过催化模板DNA与同源单链DNA引物间的突触形成。此酶显著增强了T4 DNA聚合酶全酶在线性单链DNA模板上进行的回跳（发夹引物）DNA合成反应。
T38156	N-Acetyl-DL-penicillamine
	N-Acetyl-DL-penicillamine is a chelating agent.1,2,3It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM.1,2N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the biological half-life of mercury and decreases liver, kidney, brain, and blood mercury levels, as well as increases urinary excretion of mercury in a concentration-dependent manner, in mi...
T82012	Janelia Fluor® 635, SE JF635, NHS,JF635, SE
	Janelia Fluor® 635, SE（JF635, SE）为红色荧光染料，具备NHS酯基团与伯胺基共轭的特性。JF635, SE常用于作为自标记标签如HaloTag及SNAP-tag的配体，在活细胞成像领域得到应用。

化合物

Cat.No: T23375

Target: Others

SNAP 94847 hydrochloride

Cat.No: T8004

Target: GPR, Melanin-concentrating Hormone Receptor (MCHR)

Cat.No: T28822

Synonym: SNAP-398299,SNAP398299

Cat.No: T5406

Synonym: SNAP-94847

Target: GPR, Melanin-concentrating Hormone Receptor (MCHR)

Cat.No: T5455

Synonym: SNAP37889,SNAP-37889

Target: Neuropeptide Y Receptor

Cat.No: T16831

Target: Others, GABA Receptor

Cat.No: T15688

Synonym: SNAP 6383

Target: Adrenergic Receptor

Cat.No: T70437

Cat.No: T28823

Synonym: SNAP7941

Cat.No: T23374

Target: Others

Cat.No: T34666

Synonym: SNAP8719

S-Nitroso-N-acetyl-DL-penicillamine

Cat.No: T12808

Synonym: N-乙酰基-3-(硫代亚硝基)-DL-缬氨酸,SNAP

Target: NO Synthase

SNAP8 Acetate(868844-74-0,free base)

Cat.No: T6990L

Target: Others

Cat.No: T6990

Synonym: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2,SNAP 8,SNAP-8

Target: Others

SNAP-25 187-203

Cat.No: TP1576

Cat.No: T39468

Cat.No: T39469

Cat.No: T38538

Cat.No: T39487

Janelia Fluor® 646 TFA

Cat.No: T78396

Synonym: JF646 TFA

PA Janelia Fluor® 646, SE

Cat.No: T39504

Synonym: PA-JF646-NHS

T4 UvsX Recombinase

Cat.No: T79925

Target: DNA/RNA Synthesis

N-Acetyl-DL-penicillamine

Cat.No: T38156

Janelia Fluor® 635, SE

Cat.No: T82012

Synonym: JF635, NHS,JF635, SE

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02245	SNAP-25 Protein, Human, Recombinant (His) synaptosomal-associated protein, 25kDa,SEC9,SNAP,RI...	Human	E. coli
	Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-00151	Alpha SNAP Protein, Human, Recombinant (His) N-ethylmaleimide-sensitive factor attachment protein, alpha,...	Human	E. coli
	NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. NAPA overexpression decreased the ubiquitination and degradation of s...
TMPY-03616	NAPG Protein, Human, Recombinant (His) γSNAP,GAMMASNAP,N-ethylmaleimide-sensitive...	Human	E. coli
	NAPG (NSF Attachment Protein Gamma, also known as gamma SNAP) is a Protein Coding gene. This gene encodes soluble NSF attachment protein gamma. The encoded protein mediates platelet exocytosis and controls the membrane fusion events of this process. NAPG is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. NAPG belongs to the SNAP family. It is widely expressed in the brain, thyroid, and other tissues. SNAPs enable N-ethyl-maleimide-sensitive fusion prot...

重组蛋白

SNAP-25 Protein, Human, Recombinant (His)

Cat.No: TMPY-02245

Species: Human

Expression System: E. coli

Alpha SNAP Protein, Human, Recombinant (His)

Cat.No: TMPY-00151

Species: Human

Expression System: E. coli

NAPG Protein, Human, Recombinant (His)

Cat.No: TMPY-03616

Species: Human

Expression System: E. coli

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