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Search Results for " riα "
Targets Recommended: DNA/RNA Synthesis

12

抑制剂 & 化合物

7

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T2628 RI-2

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
RI-2 是一种可逆的RAD51抑制剂,IC50值为 44.17 μM,可抑制人体细胞中的同源重组修复。
T2276 RI-1

RI-1; 3-氯-1-(3,4-二氯苯基)-4-(4-吗啉基)-1H-吡咯-2,5-二酮,RI1,RAD51 inhibitor 1

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
RI-1 (RAD51 inhibitor 1) 是一种选择性 RAD51的抑制剂,IC50值为 5-30 μM,可以破坏人类细胞中的同源重组。它在半胱氨酸 319 处与 RAD51 蛋白表面共价结合,并通过直接结合到 RAD51 细丝中蛋白质亚基之间的界面的蛋白质表面来灭活 RAD51。
T9523 TGFβRI-IN-3

TGF-beta/Smad Stem Cells
TGFβRI-IN-3 抑制TGFβR1,IC50为 0.79 nM,是对 MAP4K4 的选择性2000 倍。TGFβRI-IN-3 是一种高选择性的 TGFβR1 抑制剂,在免疫肿瘤中具有潜在的应用。
T39615L P8RI acetate

Integrin Cytoskeletal Signaling
P8RI acetate 是 CD31 的仿生肽和 CD3 的激动剂。 P8RI acetate 通过恢复 CD31 抑制途径显示出免疫抑制作用。
T39615 P8RI

D-P8RI

P8RI (D-P8RI) is a CD31 biomimetic peptide and agonist that specifically targets the juxtamembrane amino acid sequence of the ectodomain of CD31. By restoring the CD31 inhibitory pathway, P8RI exhibits immunosuppressive properties.
T37140 5'-O-DMT-rI

5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1]. [1]. Kadokura M. Synthesis of 4-thiouridine, 6-thioinosine, and 6-thioguanosine 3’,5’-O-bisphosphates as donor molecules for RNA ligation and their application to the synthesis of photoactivatable TMG-capped U1 snRNA fragments. J Org Chem. 2000 Aug 25;65(17):5104-13.
T73493 RI-962

RIP kinase Apoptosis; NF-κB
RI-962 是一种针对受体相互作用蛋白激酶 1 (RIPK1) 的高效选择性抑制剂,具有35.0 nM的IC50。本化合物主要用于神经系统疾病和炎症性疾病研究领域。
T62559 TGFβRI-IN-4

TGFβRI-IN-4 是一种高效的、口服具有活力的 TGFβ 受体 I 型激酶 (TGFβRI) 抑制剂,能够作用于 ALK5 (IC50: 44 nM) 和 NIH3T3 (IC50: 42.5 nM)。TGFβRI-IN-4 在异种移植瘤模型中,能够抑制肿瘤生长和肿瘤重量。
T60931 TGFβRI-IN-5

TGFβRI-IN-5 (Compound 4b) 是 TGFβRI 的有效抑制剂,IC50值为 0.08 μM。TGFβRI-IN-5 对所有测试细胞系的均显示出显著的抗癌活性,可增强细胞凋亡并抑制细胞周期的 G2/M 期。
T72976 TGFβRI-IN-6

TGFβRI-IN-6 是一种有效的TGFβRI 抑制剂,IC50值为 0.55 nM。TGFβRI-IN-6 具有增强抗肿瘤免疫力的潜力。
T38676 5'-O-DMT-2'-O-TBDMS-rI

5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside utilized in the synthetic process of deoxyribonucleic acid (DNA) or nucleic acid.
TP2129 RI-STAD 2

AKAP disruptor. Selectively binds PKA-RI with high affinity (KD values are 6.2 and 12.1 nM for the RIα and β subunits, respectively) and blocks its interaction with AKAP. Inhibits type I PKA-mediated phosphorylation in live cells. Cell permeable.

化合物

RI-2
Cat.No: T2628
Synonym:
Target: DNA/RNA Synthesis
RI-1
Cat.No: T2276
Synonym: RI-1; 3-氯-1-(3,4-二氯苯基)-4-(4-吗啉基)-1H-吡咯-2,5-二酮,RI1,RAD51 inhibitor 1
Target: DNA/RNA Synthesis
TGFβRI-IN-3
Cat.No: T9523
Synonym:
Target: TGF-beta/Smad
P8RI acetate
Cat.No: T39615L
Synonym:
Target: Integrin
P8RI
Cat.No: T39615
Synonym: D-P8RI
Target:
5'-O-DMT-rI
Cat.No: T37140
Synonym:
Target:
RI-962
Cat.No: T73493
Synonym:
Target: RIP kinase
TGFβRI-IN-4
Cat.No: T62559
Synonym:
Target:
TGFβRI-IN-5
Cat.No: T60931
Synonym:
Target:
TGFβRI-IN-6
Cat.No: T72976
Synonym:
Target:
5'-O-DMT-2'-O-TBDMS-rI
Cat.No: T38676
Synonym:
Target:
RI-STAD 2
Cat.No: TP2129
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-05084 Fc epsilon RI Protein, Human, Recombinant

alpha polypeptide,FcERI,α polypeptide,Fc fragment of IgE, hi...

Human HEK293 Cells
Fc epsilon RI Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P12319.
TMPY-03054 Fc epsilon RI Protein, Human, Recombinant (His)

Fc ε RI,α polypeptide,Fc fragment of IgE, high affinity I, r...

Human HEK293 Cells
Fc epsilon RI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P12319.
TMPY-05207 PRKAR1A Protein, Mouse, Recombinant (His)

1300018C22Rik,protein kinase, cAMP-dependent, regulatory, ty...

Mouse Baculovirus Insect Cells
PRKAR1A Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.6 kDa and the accession number is Q9DBC7.
TMPY-03064 Fc epsilon RI Protein, Mouse, Recombinant (hFc)

α polypeptide,FcERI,Fc ε RI,Fcr-5,alpha polypeptide,Fce1a,Fc...

Mouse HEK293 Cells
Fc epsilon RI Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P20489.
TMPK-00149 Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)

Fc-ε RI-α,Fc-epsilon RI-alpha,FCER1A,Fc-epsilon RI-α,FCE1A,F...

Human HEK293 Cells
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic dis...
TMPK-00241 Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated

FcERI,CD64,FLJ18345,IGFR1,Fc gamma RI,Fcgr,Fcr,Fc γ RI/CD64,...

Human HEK293 Cells
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma  RI (also known as CD64), Fc gamma  RII (CD32), and Fc gamma  RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight i...
TMPK-00240 Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi)

FcgRI,IGFR1,FCE1A,FCGR1A,Fc-γ RIA,Fc gamma RI,Fc-gamma RIA,F...

Human HEK293 Cells
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma  RI (also known as CD64), Fc gamma  RII (CD32), and Fc gamma  RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 33.5 kDa and...

重组蛋白

Fc epsilon RI Protein, Human, Recombinant
Cat.No: TMPY-05084
Species: Human
Expression System: HEK293 Cells
Fc epsilon RI Protein, Human, Recombinant (His)
Cat.No: TMPY-03054
Species: Human
Expression System: HEK293 Cells
PRKAR1A Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05207
Species: Mouse
Expression System: Baculovirus Insect Cells
Fc epsilon RI Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03064
Species: Mouse
Expression System: HEK293 Cells
Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)
Cat.No: TMPK-00149
Species: Human
Expression System: HEK293 Cells
Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00241
Species: Human
Expression System: HEK293 Cells
Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00240
Species: Human
Expression System: HEK293 Cells
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