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Cat. No. | Product Name | Target | Signaling Pathways |
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T0208 |
Prednisolone disodium phosphate
泼尼松龙21-磷酸二钠,Prednisolone phosphate sodium,Prednisolone 21-phosphate disodium,泼尼松龙磷酸钠 |
Glucocorticoid Receptor | Endocrinology/Hormones |
Prednisolone disodium phosphate是一种合成的糖皮质素,具有抗炎和免疫调节作用。 | |||
T0337 |
Prednisolone acetate
Omnipred,醋酸泼尼松龙,Prednisolone-21-acetate |
Glucocorticoid Receptor | Endocrinology/Hormones |
Prednisolone acetate (Omnipred) 是一种肾上腺皮质激素类药物,具有抗炎、抗过敏和抑制免疫等多种药理活性。 | |||
T19480 |
NO-prednisolone
NCX-1015 |
IL Receptor | Immunology/Inflammation |
NO-prednisolone (NCX-1015) 是一种有效刺激体内IL-10产生的化合物,是一种释放一氧化氮(NO)的Prednisolone 衍生物。 | |||
T13825 |
Prednisolone hemisuccinate
泼尼松龙半琥珀酸酯,Prednisolone 21-hemisuccinate |
Others | Others |
Prednisolone hemisuccinate is a synthetic glucocorticoid, and is treatment a variety of inflammatory and auto-immune conditions. | |||
T34126 | Prednisolone sodium metazoate | ||
Prednisolone sodium metazoate is used in the treatment of Inflammatory Bowel Disease, Ulcerative Colitis, and GI Disorders. | |||
T12535 |
Prednisolone Tebutate
|
Others | Others |
Prednisolone Tebutate is a synthetic glucocorticoid, and is an antiinflammatory and immunosuppressant. | |||
T12507 |
Prednisolone farnesylate
泼尼松龙法尼酯,PNF21 |
Others | Others |
Prednisolone farnesylate is a novel transdermal corticosteroid with anti-inflammatory activity. | |||
T20734 |
Prednisolone valerate acetate
Lidomex,Acepreval |
||
Prednisolone valerate acetate, a derivative of Prednisolone, is a synthetic corticosteroid. It is metabolically interconverted with prednisone. Prednisolone 21-Acetate Valerate is used for imaging-guided therapy evaluated in experimental cancer in a multi | |||
T1076 |
Dexamethasone
MK 125,Prednisolone F,NSC 34521,Hexadecadrol,地塞米松 |
Glucocorticoid Receptor; Mitophagy; IL Receptor; SARS-CoV; Antibacterial; Antibiotic; Autophagy; Complement System | Autophagy; Endocrinology/Hormones; Immunology/Inflammation; Microbiology/Virology |
Dexamethasone (Hexadecadrol) 是一种糖皮质激素受体激动剂和一种 IL 受体调节剂。Dexamethasone 具有抗炎和免疫抑制活性,可诱导自噬。Dexamethasone 抑制 LPS 诱导的巨噬细胞炎症反应。 | |||
T14154 |
Alclometasone
7a-Chloro-16a-methyl prednisolone |
||
Alclometasone (7a-Chloro-16a-methyl prednisolone), a glucocorticoid, inhibits leukocytes from releasing pro-inflammatory mediators. It is effective in treating corticosteroid-responsive dermatoses such as atopic dermatitis, psoriasis, allergic dermatitis, and eczema [1]. | |||
T9047 |
Fluprednisolone
NSC-47439,NSC 47439,氟泼尼龙,NSC47439 |
Others | Others |
Fluprednisolone (NSC-47439) 是一种合成糖皮质激素,具有抗炎特性。 | |||
T0294 |
6α-Methylprednisolone 21-hemisuccinate sodium salt
Asmacortone,Methylprodnisolone Sodium Succinate,甲强龙琥珀酸钠,Metypresol,Methylprednisolone sodium succinate,Corticel,6-Methylprednisolone succinate sodium |
Glucocorticoid Receptor; Glucagon Receptor | Endocrinology/Hormones; GPCR/G Protein |
6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone) 是一种糖皮质激素,是一种有效的抗炎剂,半衰期比 Prednisolone 长。 | |||
T22367 |
Methylprednisolone succinate
Methylprednisolone hemisuccinate,Methylprednisolone hydrogen succinate,甲基泼尼松龙琥珀酸酯 |
Glucocorticoid Receptor | Endocrinology/Hormones |
Methylprednisolone succinate (Methylprednisolone hemisuccinate) 是合成的糖皮质激素,常用作抗炎剂。 | |||
T1171L |
Methylprednisolone Aceponate
MPA,SH 440,SH-440,SH440,Advantan,醋丙甲泼尼龙 |
Others | Others |
Methylprednisolone Aceponate (SH 440) 是一种非卤化皮质类固醇,是一种有效的抗炎剂。 | |||
T8339 |
16α-Hydroxyprednisolone
16alpha-羟基泼尼松龙,16alpha-Hydroxyprednisolone |
Others; Drug Metabolite | Metabolism; Others |
16α-Hydroxyprednisolone 是糖皮质激素布地奈德 22(R) epimer 构型的代谢物,经过 CYP3A 酶代谢生成。 | |||
T21338 |
Methylprednisolone Acetate
Depo-Medrate,Depometicort,Depo-Medrin,Depo-medrol,Depomedrone,Lemod |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Methylprednisolone Acetate(Depo-Medrate) 具有抑制氧自由基的能力,可用于治疗急性脊髓损伤。 | |||
T29328 |
21-deacetyldeflazacort
|
Others | Others |
21-deacetyldeflazacort 是 Deflazacort 的代谢物,它是一种全身性皮质类固醇和泼尼松龙的衍生物。 | |||
T0181 |
Loteprednol etabonate
Lotemax,Alrex,氯替泼诺 |
Glucocorticoid Receptor; Antibacterial; Antibiotic | Endocrinology/Hormones; Microbiology/Virology |
Loteprednol etabonate (Lotemax) 是具有抗炎活性的皮质类固醇,用于眼科。 | |||
T3097 |
Mycophenolic Acid Impurity
马替麦考酚酸杂质,5,7-dihydroxy-4-methylphthalide |
Others | Others |
Mycophenolic Acid Impurity (5,7-dihydroxy-4-methylphthalide) 是一种免疫抑制药物和有效的抗增殖剂,可用于代替旧的抗增殖剂 azathioprine。它通常用作三联疗法的一部分,包括钙调神经磷酸酶抑制剂(ciclosporin 或 tacrolimus)和prednisolone。它还可用于研究选择表达编码 XGPRT(黄嘌呤鸟嘌呤磷酸核糖基转移酶)的大肠杆菌基因的动物细胞。 | |||
T4313 |
Tinoridine hydrochloride
盐酸替诺立定,Nonflamin,Y-3642 hydrochloride |
COX; Glutathione Peroxidase | Immunology/Inflammation; Metabolism; Neuroscience |
Tinoridine hydrochloride (Y-3642 hydrochloride) 是非甾体抗炎药,具有显著的自由基清除和抗过氧化物特性。 | |||
T74096 | Prednimustine | ||
Prednimustine (Leo 1031;NSC 134087) 是由 Prednisolone 和 Chlorambucil 形成的酯。Prednimustine 可用于白血病和淋巴瘤的研究。 | |||
T19546 |
Deprodone propionate
丙酸地泼罗酮,RD20000 |
Others | Others |
Deprodone propionate, a corticosteroid, is synthesized by esterification with propionic acid at the 17-position and deoxidation at the 21-position of the prednisolone skeleton. | |||
T33218 |
Mazipredone
Mazipredonum,Mazipredona |
||
Mazipredone is a water-soluble, long-acting prednisolone derivative used topically for skin conditions & parenterally as a glucocorticoid. | |||
T17291 |
ZK 216348
(+)-ZK 216348 |
Others | Others |
ZK 216348 also binds to Progesterone and mineralocorticoid receptors (IC50s: 20.4 nM and 79.9 nM, respectively). ZK 216348 is a nonsteroidal selective glucocorticoid receptor agonist (IC50: 20.3 nM). ZK 216348 has an anti-inflammatory activity similar to | |||
T37613 |
Ibuprofen Carboxylic Acid
|
||
Ibuprofen carboxylic acid is a major metabolite of ibuprofen . It prevents fructose-, cyanate-, and prednisolone-induced inactivation of catalase and fructose- and cyanate-induced inactivation of fumarase when used at a concentration of 2 mM and penetrates into the lens of isolated bovine eyes. Ibuprofen carboxylic acid has been found in bank filtrate and surface water, as well as influent and effluent wastewater, and is considered a micropollutant. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1560 |
Prednisolone
氢化泼尼松,Predonine,Hydroretrocortine,泼尼松龙,Metacortandralone |
Glucocorticoid Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Prednisolone (Hydroretrocortine) 是有口服活性的皮质类固醇和糖皮质激素。它的抗炎特性约为氢化可的松的四倍,同时减少了水和盐的保留。它能够用于眼部抗炎研究。 |