25
2
25
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20920 |
PST2286
PST 2286,17Hydroxydigitoxigenin,17-Hydroxydigitoxigenin,17 Hydroxydigitoxigenin,PST-2286 |
Others | Others |
PST2286 (17-Hydroxydigitoxigenin) 是一种罗他福辛代谢物。 | |||
T2621 |
Rostafuroxin
PST 2238 |
ATPase; RSV | Membrane transporter/Ion channel; Microbiology/Virology |
Rostafuroxin (PST 2238) 是洋地黄毒苷衍生物,是一种口服有效的 Na+,K+-ATPase 抑制剂,具有抗高血压和抗 RSV 活性,用于研究治疗原发性高血压的试验。 | |||
T69974 |
Phenamil
|
||
Phenamil is an irreversible inhibitor of amiloride-sensitive Na channels; derivative of amiloride, synergizing bone formation with BMP2 and inhibits BMP2 induced cyst-like bone formation. | |||
T15600 |
Istaroxime
PST2744 |
Others | Others |
Istaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM). | |||
T15599 |
Istaroxime hydrochloride
PST2744 hydrochloride |
Others | Others |
Istaroxime hydrochloride is an inhibitor of Na+/K+-ATPase (IC50: 0.11 μM). It also is a sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA 2) activator. | |||
TP1304 |
Compstatin
坎普他汀 |
Complement System | Immunology/Inflammation |
Compstatin 是一种环状十三肽,是补体系统 C3的特异性抑制剂。它只抑制灵长类补体系统的激活,可结合到狒狒的 C3,并对狒狒血液中的蛋白水解裂解具有抗性。它对补体经典途径和旁路途径的 IC50值分别为 63 和 12 μM。 | |||
T3695 |
Pepstatin
抑肽素,Pepstatin A,Pepsin Inhibitor S 735A,Ahpatinin C |
Amino Acids and Derivatives; Proteasome; HIV Protease; Autophagy | Autophagy; Metabolism; Microbiology/Virology; Proteases/Proteasome; Ubiquitination |
Pepstatin (Pepsin Inhibitor S 735A) 是由放线菌类产生的特异性天冬氨酸蛋白酶抑制剂,可抑制 HIV 蛋白酶的活性。 | |||
TP2180L |
Compstatin control peptide acetate
|
Complement System | Immunology/Inflammation |
Compstatin control peptide acetate 是补体蛋白 C3 的抑制剂,通过结合和抑制补体 C3 的切割。 | |||
TP1267L |
CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 acetate
CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 acetate(254110-79-7 free base) |
Others | Others |
CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 acetate(254110-79-7 free base) 对应于 BRLF1 的氨基酸 148-156。 BRLF1 是一种转录激活因子,可直接与一些 Epstein-Barr 病毒 (EBV) 裂解基因启动子中的富含 GC 的基序结合。 | |||
T32122 | Hydroxypepstatin | ||
Hydroxypepstatin is a new peptatin produced by Streptomyces. | |||
T25938 | Pepstanone A | ||
Pepstanone A is a potent aspartyl protease inhibitor, produced by pepstatin-producing Streptomyces. | |||
TP1268 |
CEF19, Epstein-Barr Virus latent NA-3A (458-466)
CEF19,Epstein-Barr Virus latent NA-3A 458-466 |
||
CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain). | |||
T26231 |
Acetyl-pepstatin
Streptomyces pepsin inhibitor,Ac-Pepstatin,乙酰胃泌素 |
||
Streptomyces pepsin inhibitor is used as a pepsin inhibitor. | |||
T12407 |
Pepstatin Ammonium
Pepstatin A Ammonium |
Others | Others |
Pepstatin Ammonium is a specific inhibitor of aspartic proteaseproduced by actinomycetes(hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM | |||
T75775 |
Compstatin TFA
|
||
Compstatin TFA是一种含有13个残基的环肽,作为补体系统C3的高效抑制剂,显示出物种特异性。该化合物能够结合到狒狒的C3上,并抵抗狒狒血液中的蛋白质水解裂解(与人类相似)。Compstatin TFA专一性地抑制灵长类动物的补体系统激活。其对补体经典途径和旁路途径的IC50值分别为63μM和12μM。 | |||
T76289 |
EILEVPST
|
||
EILEVST为重组人纤连蛋白衍生的低分子量肽片段。该化合物能够促进细胞类型特异性α4整合素介导的粘附,适用于血栓形成相关研究。 | |||
TP1267 |
CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156)
CEF27,Epstein-Barr Virus BRLF-1 lytic 148-156 |
||
HLA-A*0301-restricted epitope from Epstein-Barr Virus , EBV BRLF-1 (148-156). | |||
T81359 |
PSTi8
|
||
PSTi8 是一种具有生物活性的肽类化合物(胰酶抑制剂8)。 | |||
T26552 |
Acetylpepstatin
Ac-Val-Val-Sta-Ala-Sta-OH,Acetyl-pepstatin |
||
Acetylpepstatin is an inhibitor of HIV-1 protease, HIV-2 protease, aspartyl protease. | |||
T70150 |
Capstafin
|
||
Capstafin is a highly potent and selective inhibitor of STAT5b. | |||
T70149 |
PomCapstafin
|
||
PomCapstafin is a prodrug of Capstafin, acting as a potent, selective STAT5b inhibitor. | |||
TP2421 |
Ysdspstst peptide
|
||
Ysdspstst peptide is a biochemical. | |||
T76457 |
PSTAIR
|
||
PSTAIR 是一种识别 Cdc28 中 PSTAIR 序列的单克隆抗体,PSTAIR 可作为上样内参。 | |||
T81556 |
Pancreastatin
|
||
Pancreastatin(胰酶素,PST),这种肽类化合物具有生物活性,能够增加肝脏的葡萄糖输出,进而导致糖尿病。 | |||
T69975 | Istaroxime oxalate | ||
Istaroxime, also known as PST-2744, is a positive inotropic agent that mediates its action through inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase). Na+/K+ ATPase inhibition increases intracellular sodium levels, which reverses the driving force of the sodium/calcium exchanger, inhibiting calcium extrusion and possibly facilitating calcium entry. Additionally, Istaroxime increases intracellular calcium by improving the efficacy by which intracellular calcium triggers sarco... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T75705 | Pepstatin Trifluoroacetate | ||
Pepstatin (Pepstatin A) Trifluoroacetate 是一种由放线菌产生的特异性天冬氨酸蛋白酶(aspartic proteases)抑制剂,口服活性强。该化合物能有效抑制hemoglobin-pepsin、hemoglobin-proctase、casein-pepsin、casein-proctase、casein-acid protease和hemoglobin-acid protease的活性,其IC50值分别为4.5 nM、6.2 nM、150 nM、290 nM、520 nM和260 nM。此外,对HIV protease也有抑制作用。 | |||
T20441 |
Lipstatin
|
||
Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02062 |
SULT1A1 Protein, Human, Recombinant (His)
HAST1/HAST2,PST,P-PST,ST1A1,STP,sulfotrans... |
Human | E. coli |
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Pa... | |||
TMPY-02948 |
SULT1A3 Protein, Human, Recombinant (His)
M-PST,HAST,SULT1A3,ST1A3/ST1A4,HAST3,SULT1A4,TL- |
Human | E. coli |
SULT1A3 belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. They are different in their tissue distributions and substrate specificities while their gene structure (number and length of exons) is similar. SULT1A3 gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 ar... | |||
TMPJ-00586 |
SULT1A2 Protein, Human, Recombinant (His)
STP2,Aryl Sulfotransferase 2,ST1A2,Phenol Sulfotransferase 2... |
Human | E. coli |
Sulfotransferase 1A2 (SULT1A2) is a member of the Sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1A2 is a cytoplasmic protein and exists as a homodimer. SULT1A2 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and might thus participate as a modulating factor of cancer risk. | |||
TMPY-00144 |
Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350 Protein (His)
BLLF1,gp22 |
EBV | Baculovirus Insect Cells |
Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.7 kDa and the accession number is A0A0B6VN60. | |||
TMPH-00536 |
Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)
|
EBV | P. pastoris (Yeast) |
Plays a key role in the activation of the host resting B-cell and stimulation of B-cell proliferation. Acts by up-regulating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes including CD21, CD23 and MYC. Activates transcription by acting as an adapter molecule that binds to cellular sequence-specific DNA-binding proteins such as host CBF1, SMARCB1 and SPI1. Once EBNA2 is near promoter sites, its acidic activating domain recruits basal and activation-ass... | |||
TMPH-00541 |
Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)
|
EBV | E. coli |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... | |||
TMPH-00535 |
Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)
|
EBV | E. coli |
Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell. | |||
TMPY-01818 |
TPST1 Protein, Human, Recombinant (His)
tyrosylprotein sulfotransferase 1,TANGO13A |
Human | HEK293 Cells |
Protein-tyrosine sulfotransferase 1, also known as Tyrosylprotein sulfotransferase 1 and TPST1, is a single-pass type II membrane protein that belongs to the protein sulfotransferase family. Tyrosine O-sulfation is a common posttranslational modification of proteins in all multicellular organisms. This reaction is mediated by a Golgi enzyme activity called tyrosylprotein sulfotransferase (TPST) that catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to tyrosine residues... | |||
TMPH-00547 |
Epstein-Barr virus (strain B95-8) BARF1 Protein (His & Myc)
|
EBV | E. coli |
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. | |||
TMPH-00540 |
Epstein-Barr virus (strain GD1) LMP1 Protein (His)
|
EBV | P. pastoris (Yeast) |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... | |||
TMPH-00537 |
Epstein-Barr virus (strain B95-8) EBNA3 Protein (His & Myc)
|
EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. | |||
TMPH-03022 |
PstP Protein, Mycobacterium tuberculosis, Recombinant
|
Mycobacterium tuberculosis | E. coli |
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth and development of the cell. Plays a role in establishing and maintaining infection. PstP Protein, Mycobacterium tuberculosis, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.3 kDa and the accession number is P9WHW4. | |||
TMPH-00545 |
Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc)
|
EBV | E. coli |
Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency. Triggers lytic replication, and initiates a cellular senescence program in epithelial cells. Upregulates human DCR3/TNFRSF6B by directly binding to its receptor. Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is Q3KS... | |||
TMPH-00548 |
Epstein-Barr virus (strain B95-8) BZLF1 Protein (His & SUMO)
|
EBV | E. coli |
Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 activates the promoter of another EBV gene (BSLF2+BMLF1). | |||
TMPH-00538 |
Epstein-Barr virus (strain GD1) EBNA3 Protein (His & Myc)
|
EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. | |||
TMPH-00539 |
Epstein-Barr virus (strain B95-8) BDLF3 Protein (His & Myc)
|
EBV | E. coli |
Epstein-Barr virus (strain B95-8) BDLF3 Protein (His & Myc) is expressed in E. coli. | |||
TMPH-00544 |
Epstein-Barr virus (strain B95-8) LMP2 Protein (His & SUMO)
|
EBV | E. coli |
Epstein-Barr virus (strain B95-8) LMP2 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.6 kDa and the accession number is P13285. | |||
TMPH-00542 |
Epstein-Barr virus (strain Raji) LMP1 Protein (His)
|
EBV | P. pastoris (Yeast) |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... | |||
TMPY-06899 |
Epstein-Barr virus (EBV) (strain B95-8) gH & gL Heterodimer Protein (His & Flag)
|
EBV | HEK293 Cells |
Epstein-Barr virus (EBV) (strain B95-8) gH & gL Heterodimer Protein (His & Flag) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 89.51 kDa and the accession number is P03231. | |||
TMPH-00546 |
Epstein-Barr virus (strain GD1) BARF1 Protein (His)
|
EBV | E. coli |
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. | |||
TMPY-06322 |
Epstein-Barr virus (B95-8) Glycoprotein gp350 Protein (His & Avi), Biotinylated
gp22,BLLF1 |
EBV | HEK293 Cells |
Epstein-Barr virus (B95-8) Glycoprotein gp350 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 55.51 kDa and the accession number is YP_401667.1. | |||
TMPH-03021 |
PstP Protein, Mycobacterium tuberculosis, Recombinant (His)
|
Mycobacterium tuberculosis | E. coli |
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth and development of the cell. Plays a role in establishing and maintaining infection. | |||
TMPH-00550 |
Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc)
|
EBV | E. coli |
Plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. Inhibits IFN-gamma synthesis. Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted m... | |||
TMPH-00543 |
Epstein-Barr virus (strain Raji) LMP1 Protein (His & SUMO)
|
EBV | E. coli |
Epstein-Barr virus (strain Raji) LMP1 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.0 kDa and the accession number is P13198. | |||
TMPH-00549 |
Epstein-Barr virus (strain GD1) BZLF1 Protein (His & Myc)
|
EBV | E. coli |
Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 activates the promoter of another EBV gene (BSLF2+BMLF1). |