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Search Results for " pea "

24

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T17977	Fmoc-PEA
	Fmoc-PEA 是一种可降解的抗体偶联药物 (ADC)的linker。
T7495	Hexa-D-arginine	Others	Others
	Hexa-D-arginine 是稳定的furin 抑制剂，能够作用于 furin (Ki:106 nM)、PACE4 (Ki:580 nM)、PC1 (Ki:13.2 nM)。它在体外和体内均可阻断假单胞菌外毒素 A 和炭疽毒素的毒性。
T8639	Phenibut (hydrochloride) 3-Amino-4-phenylbutyric acid hydrochloride,3-氨基-4-苯基丁酸盐酸盐	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) 是 GABA-B 激动剂，口服有活性，可作用于 GABAB 受体，充当 GABA 类似物。它具有促智 (增强认知) 及抗焦虑的能力。
T2990	Phenibut Phenybut,Fenigam,非尼布特,Fenibut,PhGABA,Aminophenylbutyric acid,β-Phenyl-γ-aminobutyric acid	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Phenibut (Aminophenylbutyric acid) 是GABA-B 激动剂，可作为 GABA 类似物，主要作用于 GABAB 受体，具有抗焦虑和增强认知的作用。
T4171	PEAQX NVP-AAM077	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	PEAQX (NVP-AAM077) 是 NR2A 高效选择性 NMDA 受体拮抗剂，IC50值为270nM。
T16451	PEAQX tetrasodium hydrate NVP-AAM077 tetrasodium hydrate,PEAQX tetrasodium hydrate (459836-30-7 free base),PEAQX tetrasodium hydrate	Apoptosis; NMDAR; iGluR	Apoptosis; Membrane transporter/Ion channel; Neuroscience
	PEAQX tetrasodium hydrate (PEAQX tetrasodium hydrate (459836-30-7 free base)) 是一种可口服的NMDA 拮抗剂，具有有效性和选择性。PEAQX tetrasodium hydrate (459836-30-7 free base) 对 hNMDAR 1A/2A 的 IC50 值分别为 270 nM 对hNMDAR 1A/2B 的 IC50 值为29600 nM。
T9796	22393-62-0_peak 2
	22393-62-0_peak 2 exhibits some aspects of the antiestrogenic activity and other actions that may be connected to the estrogenic properties. A mixture of the (Z)- and (E)-isomers (Broparestrol, INN) is used in dermatology.
T29239	(-)-Inpea HCl (-)-Inpea hydrochloride,l-Inpea hydrochloride
	(-)-Inpea HCl is a bioactive chemical.
T19200	Azonafide-PEABA	Others	Others
	Azonafide-PEABA 是一种具有细胞毒性的药物。
T126169	Hopeachinol B
	Hopeachinol B 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126169。
T69906	PEAQX sodium
	PEAQX, also known as NVP-AAM077; is a competitive antagonist at the NMDA receptor. Although originally described as 100-fold selective for GluN1/GluN2A receptors vs. GluN1/GluN2B receptors, more detailed studies of the Ki of PEAQX revealed it only shows a 5 fold difference in affinity for GluN1/GluN2A vs. GluN1/GluN2B receptors. It is also a potent anticonvulsant in animal tests.
T11603	Ibrutinib-MPEA	Others	Others
	Ibrutinib-MPEA is ibrutinib derivative. Ibrutinib is a covalent and irreversible BTK inhibitor that has been used to treat hematological malignancies.
T40409	Tau Peptide (275-305) (Repeat 2 domain)
	Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer's tau peptide. Tau Peptide (275-305) is considered crucial in determining the biochemical characteristics of the complete tau protein.
T38591	Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)
	Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, utilized for synthesizing PROTACs.
T32077	Hippeastrine Hydrobromide (+)-Hippeastrine HBr,Hippeastrine HBr
	Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.
T75337	Cy5.5-SE (DIPEA)
	Cy5.5-SE (Cyanine5.5 NHS ester) DIPEA 是一种以奇数个甲基单位连接两个氮原子的花菁(Cyanine)染料。该染料特点包括长波长、可调吸收发射、高消光系数、良好水溶性及合成相对简单。常用于蛋白、抗体和小分子化合物的标记，特别是蛋白抗体的标记，通过简单混合反应即可完成结合。储存应避光。
TP2292	survivin (baculoviral IAP repeat-containing protein 5) (21-28)	Others	Others
	Survivin (baculoviral inhibitor of apoptosis IAP repeat-containing protein-5) is a member of the IAP gene family, which has been implicated in both inhibitions of apoptosis and mitosis regulation1. Survivin is one of the most uniformly up-regulated genes
T31505	d-Inpea HCl L-(+)-Inpea hydrochloride,d-Inpea hydrochloride,(+)-Inpea hydrochloride
	d-Inpea HCl is a bioactive chemical.
T10370	ARN 077 URB913	Others	Others
	ARN 077 is a selective N-acylethanolamine acid amidase (NAAA) inhibitor (IC50: 7 nM for human NAAA). ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS.
T38049	Glycerophospho-N-Palmitoyl Ethanolamine
	N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. For example, arachidonoyl ethanolamide (AEA) is an endogenous neurotransmitter that evokes cellular responses by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). The different types of NAE are derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1). Glycerophospho-N-palmitoyl ethanolamine (GP-NPEA) is the metabo...
T60432	NAAA-IN-3
	NAAA-IN-3 (Compound 17a) 是一种有效的、选择性的 NAAA 抑制剂，IC50为 50 nM。NAAA 是一种半胱氨酸酰胺酶，它优先水解内源性生物脂棕榈酰乙醇酰胺 (PEA) 和油酰乙醇酰胺 (OEA)。PEA 是核过氧化物酶体增殖物激活受体-α (PPAR-α) 的内源性激动剂，PPAR-α 是炎症和疼痛的关键调节因子。 NAAA-IN-3 的潜在作用是作为炎症和疼痛的治疗剂。
T60378	NAAA-IN-2
	NAAA-IN-2 (Compound 9) 是一种有效的、选择性的NAAA 抑制剂，IC50为 50 nM。NAAA 是一种半胱氨酸酰胺酶，优先水解内源性生物脂棕榈酰乙醇酰胺 (PEA) 和油酰乙醇酰胺 (OEA)。NAAA-IN-2 在炎症和疼痛的研究中具有潜力。
T60957	Palmitoyl serinol
	Palmitoyl serinol (N-Palmitoyl serinol) 是内源性大麻素 N-棕榈酰乙醇胺(PEA) 的类似物，可改善正常和发炎皮肤的表皮通透性屏障。
T60767	NAAA-IN-1
	NAAA-IN-1 (Compound 1) 可用于炎症和疼痛的研究。NAAA-IN-1 是NAAA 的选择性抑制剂 (IC50 = 7 nM)。NAAA 优先水解内源性生物脂棕榈酰乙醇酰胺 (PEA) 和油酰乙醇酰胺 (OEA)，是一种半胱氨酸酰胺酶。

化合物

Cat.No: T17977

Hexa-D-arginine

Cat.No: T7495

Target: Others

Phenibut (hydrochloride)

Cat.No: T8639

Synonym: 3-Amino-4-phenylbutyric acid hydrochloride,3-氨基-4-苯基丁酸盐酸盐

Target: GABA Receptor

Cat.No: T2990

Synonym: Phenybut,Fenigam,非尼布特,Fenibut,PhGABA,Aminophenylbutyric acid,β-Phenyl-γ-aminobutyric acid

Target: GABA Receptor

Cat.No: T4171

Synonym: NVP-AAM077

Target: NMDAR, iGluR

PEAQX tetrasodium hydrate

Cat.No: T16451

Synonym: NVP-AAM077 tetrasodium hydrate,PEAQX tetrasodium hydrate (459836-30-7 free base),PEAQX tetrasodium hydrate

Target: Apoptosis, NMDAR, iGluR

22393-62-0_peak 2

Cat.No: T9796

Cat.No: T29239

Synonym: (-)-Inpea hydrochloride,l-Inpea hydrochloride

Azonafide-PEABA

Cat.No: T19200

Target: Others

Cat.No: T126169

Cat.No: T69906

Cat.No: T11603

Target: Others

Tau Peptide (275-305) (Repeat 2 domain)

Cat.No: T40409

Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)

Cat.No: T38591

Synonym: Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)

Hippeastrine Hydrobromide

Cat.No: T32077

Synonym: (+)-Hippeastrine HBr,Hippeastrine HBr

Cy5.5-SE (DIPEA)

Cat.No: T75337

survivin (baculoviral IAP repeat-containing protein 5) (21-28)

Cat.No: TP2292

Target: Others

Cat.No: T31505

Synonym: L-(+)-Inpea hydrochloride,d-Inpea hydrochloride,(+)-Inpea hydrochloride

Cat.No: T10370

Synonym: URB913

Target: Others

Glycerophospho-N-Palmitoyl Ethanolamine

Cat.No: T38049

Cat.No: T60432

Cat.No: T60378

Palmitoyl serinol

Cat.No: T60957

Cat.No: T60767

Cat. No.	Product Name	Target	Signaling Pathways
TN6233	Hopeaphenol (+)-Hopeaphenol
	Hopeaphenol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6233，CAS号为 388582-37-4。
T75655	Hippeastrine
	Hippeastrine 是一种活性生物碱，对拓扑异构酶 ITop I 具有良好的剂量依赖性抑制作用，IC50为7.25 μg/mL。具有抗增殖和抗癌活性。
TN6234	Isohopeaphenol (-)-Isohopeaphenol
	Isohopeaphenol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6234，CAS号为 197446-77-8。
T4914	Mesoxalate sodium (monohydrate) Sodium mesoxalate monohydrate,丙酮二酸钠	Others; Endogenous Metabolite	Metabolism; Others
	Mesoxalate sodium (monohydrate) 是内源性代谢产物的一种。
T4714	Methyl 2-(1H-indol-3-yl)acetate Methyl indole-3-acetate,吲哚-3-醋酸甲酯,Indole-3-acetic acid, methyl ester	Others; Endogenous Metabolite	Metabolism; Others
	苹果中含有 Methyl 2-(1H-indol-3-yl)acetate (Methyl indole-3-acetate)。它是从海豌豆(Lathyrus maritimus)、紫豆(Vicia amurensis)、野生大豆(Glycine soja)、野豆(Vigna catiang var. sinensis)和风信子豆(Dolichos lablab)的未成熟种子中分离得到的。
TN4800	Pisatin	NADPH-oxidase; P450	Immunology/Inflammation; Metabolism
	Pisatin is an isoflavonoid phytoalexin synthesized by pea (Pisum sativum L.).
T4S1585	Dencichin
	Dencichine is a haemostatic agent present , it is also a reported neurotoxic agent found in Lathyrus sativus (grass pea seed).
TN1690	Glabrene	Others; Estrogen/progestogen Receptor; Tyrosinase	Endocrinology/Hormones; Others; Proteases/Proteasome
	Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely the major contributors to the notable synergistic antioxidant activity when coupled with pea pr

天然产物

Cat.No: TN6233

Synonym: (+)-Hopeaphenol

Cat.No: T75655

Cat.No: TN6234

Synonym: (-)-Isohopeaphenol

Mesoxalate sodium (monohydrate)

Cat.No: T4914

Synonym: Sodium mesoxalate monohydrate,丙酮二酸钠

Target: Others, Endogenous Metabolite

Methyl 2-(1H-indol-3-yl)acetate

Cat.No: T4714

Synonym: Methyl indole-3-acetate,吲哚-3-醋酸甲酯,Indole-3-acetic acid, methyl ester

Target: Others, Endogenous Metabolite

Cat.No: TN4800

Target: NADPH-oxidase, P450

Cat.No: T4S1585

Cat.No: TN1690

Target: Others, Estrogen/progestogen Receptor, Tyrosinase

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