首页工具

登录

搜索结果

Search Results for " pai-1 "

15

抑制剂 & 化合物

2

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T2030	Tiplaxtinin PAI-039,Tiplasinin	PAI-1; Apoptosis	Apoptosis; Metabolism
	Tiplaxtinin (Tiplasinin) 是一种具有口服活性的选择性纤溶酶原激活物抑制剂-1 抑制剂，IC50为 2.7 μM。
T8962	TM5007	PAI-1	Metabolism
	TM5007 是纤溶酶原激活物抑制剂-1（PAI-1；IC50 为 29 uM）的强效抑制剂。
T4254	TM5441	PAI-1; Apoptosis	Apoptosis; Metabolism
	TM5441 是口服生物可利用的纤溶酶原激活物抑制剂-1 抑制剂，抑制多个癌症细胞系的 IC50值在 13.9 到 51.1 μM。它诱导几种人类癌症细胞的内在调亡，减弱 Nω-硝基-1-精氨酸甲酯诱导的心脏高血压和血管衰老。
T3442	UK-371804 UK371804	PAI-1; Serine Protease	Metabolism; Proteases/Proteasome
	UK-371804 是一种尿嘧啶型纤溶酶原激活物的抑制剂，Ki=10 nM。
T4255	TM5275 sodium TM5275 sodium salt	PAI-1	Metabolism
	TM5275 sodium (TM5275 sodium salt) 是一种纤溶酶原激活物抑制剂，IC50=6.95 μM。
T13257	Upamostat	PAI-1; Serine/threonin kinase; Serine Protease	Cell Cycle/Checkpoint; Metabolism; Proteases/Proteasome
	Upamostat 是一种丝氨酸蛋白酶抑制剂，也是一种具有口服活性的 WX-UK1 前药，是一种尿激酶型纤溶酶原激活剂 (uPA) 抑制剂。
T13408	ZK824190	Others; Serine Protease	Others; Proteases/Proteasome
	ZK824190 是具有口服活性尿激酶型纤溶酶原激活剂 (uPA) 选择性抑制剂，对 uPA，tPA 和 Plasmin 的IC50分别为 237，1600 和 1850 nM。ZK824190在多发性硬化症中有研究价值。
T29856	Aleplasinin PAZ 417,PAZ417,PAZ-417	PAI-1	Metabolism
	Aleplasinin (PAZ 417) 是纤溶酶原激活物抑制剂 1 (PAI-1) 的选择性和口服活性抑制剂，是纤溶系统的关键负调节剂。 Aleplasinin 可用于阿尔茨海默病研究。
T28788	SK-216 SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor
	SK-216 is a specific PAI-1 inhibitor. SK-216 reduced the extent of angiogenesis in the tumors and inhibited VEGF-induced migration and tube formation by human umbilical vein endothelial cells in vitro. SK-216 reduced the degree of bleomycin-induced pulmon
T23764	AZ3976 AZ 3976,AZ-3976	PAI-1	Metabolism
	AZ3976 是一种纤溶酶原激活物抑制剂-1抑制剂，在血浆凝块溶解试验中的 IC50为16μM。AZ3976 显示促纤维蛋白溶解活性。
T25915	Diaplasinin PAI-749,PAI749,PAI 749
	PAI-749 is a selective and effective antagonist agent of plasminogen activator inhibitor 1 (PAI-1).
T68572	IMD-1622
	IMD-1622 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor.
T25217	CDE-096
	CDE-096 is a plasminogenactivator inhibitor-1 (PAI-1) inactivator.
T70810	THR-18
	THR-18 is an 18-mer peptide derived from the sequence of human plasminogen activator inhibitor 1 (PAI-1), having the ability to bind to a site of tissue plasminogen activator (tPA) distal to its catalytic site and uncouple the beneficial clot-dissolving properties of tPA from its deleterious non-fibrinolytic effects.
T35520	Aflatoxin G1-13C17 Aflatoxin G1-13C17
	Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg/kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase...

化合物

Cat.No: T2030

Synonym: PAI-039,Tiplasinin

Target: PAI-1, Apoptosis

Cat.No: T8962

Target: PAI-1

Cat.No: T4254

Target: PAI-1, Apoptosis

Cat.No: T3442

Synonym: UK371804

Target: PAI-1, Serine Protease

Cat.No: T4255

Synonym: TM5275 sodium salt

Target: PAI-1

Cat.No: T13257

Target: PAI-1, Serine/threonin kinase, Serine Protease

Cat.No: T13408

Target: Others, Serine Protease

Cat.No: T29856

Synonym: PAZ 417,PAZ417,PAZ-417

Target: PAI-1

Cat.No: T28788

Synonym: SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor

Cat.No: T23764

Synonym: AZ 3976,AZ-3976

Target: PAI-1

Cat.No: T25915

Synonym: PAI-749,PAI749,PAI 749

Cat.No: T68572

Cat.No: T25217

Cat.No: T70810

Aflatoxin G1-13C17

Cat.No: T35520

Synonym: Aflatoxin G1-13C17

Cat. No.	Product Name	Target	Signaling Pathways
T4S0592	Toddalolactone (+)-Toddalolactone,飞龙掌血内酯,毛两面针素	PAI-1	Metabolism
	Toddalolactone ((+)-Toddalolactone) 是一种Toddalia asiatica 的主要成分，能够抑制重组人纤溶酶原激活物抑制物-1(PAI-1)的活性， IC50=37.31 μM。
T3876	Loureirin B 龙血素B,龙血素 B	PAI-1; ERK; Potassium Channel; JNK	MAPK; Membrane transporter/Ion channel; Metabolism
	Loureirin B 是从剑叶龙血树中分离到的一种黄酮，是 PAI-1抑制剂，IC50值为 26.10 μM。它抑制 KATP，以及 ERK 和 JNK 的磷酸化，具有抗糖尿病的功效。

天然产物

Cat.No: T4S0592

Synonym: (+)-Toddalolactone,飞龙掌血内酯,毛两面针素

Target: PAI-1

Cat.No: T3876

Synonym: 龙血素B,龙血素 B

Target: PAI-1, ERK, Potassium Channel, JNK

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼