首页工具

登录

搜索结果

Search Results for " oligonucleotide "

93

抑制剂 & 化合物

2

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T38423	CL097 CL097	Reactive Oxygen Species; TLR	Immunology/Inflammation; Metabolism; NF-κB
	CL097 是 TLR7 和 TLR8 的有效激动剂。 CL097 诱导巨噬细胞中的促炎细胞因子和 NADPH 氧化酶引发，从而增加 fMLF 刺激的 ROS 产生。
T18898	5(6)-TAMRA SE 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester,5(6)-羧基四甲基罗丹明琥珀酰亚胺酯	Others	Others
	5(6)-TAMRA SE (5(6)-Carboxytetramethylrhodamine N-succinimidyl ester) 是荧光染料，能够结合寡聚核苷酸，并用于DNA 测序。
T18903	6-ROX 6-Carboxy-X-rhodamine,6-羧基-X-罗丹明	Others	Others
	6-ROX (6-Carboxy-X-rhodamine) 是寡核苷酸的荧光标记物，其激发波长和发射波长均为568nm。它是耦合至5-FAM 的受体，在FRET 成像中作为供体。
T36752	Dmt-2'fluoro-da(bz) amidite	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Dmt-2'fluoro-da(bz) amidite 是一种 2'-脱氧-2'-氟代硫代磷酸酯寡核苷酸，对 RNA 靶标具有很高的亲和力和特异性。Dmt-2'fluoro-da(bz) amidite 也是 5'-DMT-3'-亚磷酰胺合成的中间体，是抗核酸酶的反义化合物。
T13254L	UNC10217938A HCl UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl	Others	Others
	UNC10217938A HCl (UNC7938 HCl) 是具有寡核苷酸 (oligonucleotides) 增强作用的 3-deazapteridine 类似物，通过调节寡核苷酸在细胞内的运输和从内体中的释放来增强寡核苷酸的作用。UNC10217938A HCl 还增强了 siRN 和反义寡核苷酸的作用。
T39479	Rovanersen WVE-120101,Rovanersen
	Rovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research.
T39517	Suvodirsen WVE-210201
	Suvodirsen (WVE-210201) is an oligonucleotide compound with potential applications in the study of Duchenne muscular dystrophy (DMD).
T13254	UNC10217938A	Others	Others
	UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects.
T40506	5'-O-DMT-dT 5'-O-DMT-dT,5'-O-(4,4'-Dimethoxytrityl)thymidine
	5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative that finds utility in oligonucleotide synthesis.
T38566	Bz-rC Phosphoramidite
	Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.
T36755	DMT-dG(dmf) Phosphoramidite
	DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer employed for oligonucleotide synthesis.
T37133	5'-O-DMT-2'-TBDMS-Uridine
	5’-O-DMT-2’-TBDMS-Uridine is a deoxyribonucleoside used for the oligonucleotide synthesis.
T38656	Nusinersen
	Nusinersen is an antisense oligonucleotide drug that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein.
T17129	Tos-PEG3	Others	Others
	Tos-PEG3, a PEG-based PROTAC linker, is suitable for synthesizing PROTACs and 3'-aminooxy oligonucleotide solid supports[1].
T37102	2'-O-Me-C(Bz) Phosphoramidite
	2’-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
T37103	2'-OMe-A(Bz) Phosphoramidite
	2’-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
T37104	2’-OMe-G(ibu) Phosphoramidite
	2’-OMe-G(ibu) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
T40776	Diguanosine 5′-triphosphate Diguanosine 5′-triphosphate,Gp3G
	Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase. Diguanosine 5′-triphosphate is a virus-specific oligonucleotide, can be used to prime reovirus transcription and inhibit RNA methylation.
T74434	Apatorsen
	Apatorsen 是一种靶向Hsp27mRNA 的反义寡核苷酸，抑制Hsp27蛋白的产生。
TD0068	5(6)-ROX N-succinimidyl ester 5(6)-ROX, SE [5-(and-6)-Carboxy-X-rhodamine, succinimidyl ester] Mixed isomers,5(6)-羧基-X-罗丹明琥珀酰亚胺酯（混合物）
	5(6)-ROX, SE is an amine-reactive fluorescent probe that is widely used for oligonucleotide labeling and automated DNA sequencing applications.
T38829	Lademirsen RG-012,SAR339375
	Lademirsen (SAR339375; RG-012) is a highly specific antisense oligonucleotide (ASO) targeting miR-21 . Lademirsen has the potential for Alport nephropathy research.
T74479	m7GpppUpG
	m7GpppUpG，作为一种oligonucleotide，属于M7GpppNpG 三核苷酸帽类似物。该化合物被应用于合成具cap 0或cap 1结构的RNA的化学工具。
T38425	Ac-dA Phosphoramidite
	Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.
T39480	Lexanersen WVE-120102,Lexanersen
	Lexanersen (WVE-120102), an antisense oligonucleotide, is utilized in Huntington's disease research.
T40556	2-Amino-2'-deoxyadenosine
	2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis.
T39141	7-Deaza-2'-deoxy-7-iodoadenosine
	7-Deaza-2'-deoxy-7-iodoadenosine is a modified oligonucleotide containing 7-Deazaadenine.
T38554	Eteplirsen 依特立生；依特普森,AVI 4658
	Eteplirsen (AVI 4658) is a synthetic antisense oligonucleotide utilized in research for Duchenne muscular dystrophy.
T40727	Mipomersen sodium
	Mipomersen (sodium), a second-generation, 20-base phosphorothioate antisense oligonucleotide (ASO), targets human apoB-100.
T36753	DMT-dC(ac) Phosphoramidite
	DMT-dC(ac) Phosphoramidite is a phosphoramidite monomer that has been modified for use in oligonucleotide synthesis.
T83297	5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT
	5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT 是带有荧光素 FAM 标记的寡核苷酸。
T39166	Tominersen IONIS-HTTRx,RG6042
	Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen can be used for the research of Huntington’s disease.
T38464	Miravirsen SPC-3649,Miravirsen
	Miravirsen (SPC-3649), a β-d-oxy-locked nucleic acid-modified phosphorothioate antisense oligonucleotide, inhibit the biogenesis of miR-122 . Miravirsen (SPC-3649) is used in the study for HCV infections.
T76238	Zilganersen
	Zilganersen (ION373) 为GFAP抑制剂，属于反义寡核苷酸类。适用于亚历山大病(AxD)的研究。
T38909	Inotersen sodium ISIS-420915 sodium
	Inotersen sodium, also known as ISIS-420915 sodium, is a 2′-O-methoxyethyl-modified antisense oligonucleotide compound. It effectively inhibits transthyretin (TTR) protein production by targeting the TTR RNA transcript, thereby reducing TTR transcript levels. Inotersen sodium holds potential for research on hereditary TTR amyloidosis polyneuropathy.
T74691	Aprinocarsen sodium
	Aprinocarsen (ISIS 3521) sodium，是针对蛋白激酶C-α（PKC-α）的特异性反义寡核苷酸抑制剂，为一种20-mer寡核苷酸，通过调节细胞分化和增殖来发挥作用。其能有效抑制人类肿瘤细胞系在裸鼠体内的生长，展示了作为人类癌症化疗化合物的潜力。
T74433	Apatorsen sodium
	Apatorsen (sodium)是一种靶向Hsp27mRNA 的反义寡核苷酸，抑制Hsp27蛋白的产生。
T39455	Viltolarsen NS-065,NCNP-01
	Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide that specifically targets the splicing of exon 53 in the dystrophin gene. It is utilized in research related to Duchenne muscular dystrophy (DMD).
T39712	RGLS4326 RG4326,RGLS4326
	RGLS4326 (RG4326) is a short oligonucleotide inhibitor of microRNA-17 (miR-17), with a pioneering role in its class. This compound, with a research focus on autosomal dominant polycystic kidney disease (ADPKD), effectively suppresses the activity of miR-17 in HeLa cells, displaying an EC50 value of 28.3 nM.
T15074	DBCO-PEG4-TAMRA	Others	Others
	DBCO-PEG4-TAMRA, contains a DBCO group, is a PEG-based TARMA dye. The TAMRA dye is a dye widely used in oligonucleotide labeling.
T39650	Tadnersen IONIS-C9Rx,BIIB078
	Tadnersen (BIIB078) is an antisense oligonucleotide (ASO) designed for the selective targeting of C9ORF72 transcript variants 1 and 3, specifically those carrying the expansion.
TD0070	6-ROX, SE [6-Carboxy-X-rhodamine, succinimidyl ester] Single isomer,6-羧基-X-罗丹明琥珀酰亚胺酯（单一化合物）
	The isomeric 6-ROX, SE is an amine-reactive form of carboxy-X-rhodamine and is widely used for oligonucleotide labeling and automated DNA sequencing applications.
T75153	ATL 1102
	ATL 1102 是一种靶向CD49dmRNA 的反义寡核苷酸
T39498	Tofersen BIIB067,ISIS-SOD1Rx
	Tofersen (BIIB067) is an antisense oligonucleotide utilized to inhibit the synthesis of superoxide dismutase 1 (SOD1) protein by facilitating the degradation of SOD1 mRNA via the RNase H-dependent mechanism. This compound holds potential for amyotrophic lateral sclerosis (ALS) research.
T39294	Cobomarsen MRG-106,Cobomarsen
	Cobomarsen (MRG-106) is an oligonucleotide inhibitor targeting miR-155. This compound effectively suppresses various gene pathways involved in cell survival, such as JAK/STAT, MAPK/ERK, and PI3K/AKT. Cobomarsen is particularly valuable in the study of B-cell lymphoma.
T74250	Custirsen
	Custirsen 是一种高度特异性的反义寡核苷酸，可抑制clusterin 的产生，clusterin 是一种抗凋亡蛋白，在化疗反应中上调表达，并导致耐药性。
T74704	5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)
	5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite 为一种高效核酸类似物，归属于修饰型反义寡核苷酸。
T39347	RG-101
	RG-101 is a hepatocyte-targeted N-acetylgalactosamine conjugated oligonucleotide that functions as an antagonist for miR-122, an essential host factor in the replication of the hepatitis C virus (HCV).
T74842	Trecovirsen
	Trecovirsen (GEM91) 是一种靶向 HIVgag 基因的反义寡核苷酸。
T21096	Decamethylene glycol alpha,omega-Decanediol,Decamethylenediol,1,10-Dihydroxydecane,Decane-1,10-diol
	Decamethylene glycol is a substance used as a reagent in the biological study of modified oligonucleotide with in vivo antitumoral activity. Also used in the pharmaceutical study on the composition of essential oils obtained from myrrh and frankincense an

化合物

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

Cat.No: T38423

Synonym: CL097

Target: Reactive Oxygen Species, TLR

Cat.No: T18898

Synonym: 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester,5(6)-羧基四甲基罗丹明琥珀酰亚胺酯

Target: Others

Cat.No: T18903

Synonym: 6-Carboxy-X-rhodamine,6-羧基-X-罗丹明

Target: Others

Dmt-2'fluoro-da(bz) amidite

Cat.No: T36752

Target: DNA/RNA Synthesis

UNC10217938A HCl

Cat.No: T13254L

Synonym: UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl

Target: Others

Cat.No: T39479

Synonym: WVE-120101,Rovanersen

Cat.No: T39517

Synonym: WVE-210201

Cat.No: T13254

Target: Others

Cat.No: T40506

Synonym: 5'-O-DMT-dT,5'-O-(4,4'-Dimethoxytrityl)thymidine

Bz-rC Phosphoramidite

Cat.No: T38566

DMT-dG(dmf) Phosphoramidite

Cat.No: T36755

5'-O-DMT-2'-TBDMS-Uridine

Cat.No: T37133

Cat.No: T38656

Cat.No: T17129

Target: Others

2'-O-Me-C(Bz) Phosphoramidite

Cat.No: T37102

2'-OMe-A(Bz) Phosphoramidite

Cat.No: T37103

2’-OMe-G(ibu) Phosphoramidite

Cat.No: T37104

Diguanosine 5′-triphosphate

Cat.No: T40776

Synonym: Diguanosine 5′-triphosphate,Gp3G

Cat.No: T74434

5(6)-ROX N-succinimidyl ester

Cat.No: TD0068

Synonym: 5(6)-ROX, SE [5-(and-6)-Carboxy-X-rhodamine, succinimidyl ester] *Mixed isomers*,5(6)-羧基-X-罗丹明琥珀酰亚胺酯（混合物）

Cat.No: T38829

Synonym: RG-012,SAR339375

Cat.No: T74479

Ac-dA Phosphoramidite

Cat.No: T38425

Cat.No: T39480

Synonym: WVE-120102,Lexanersen

2-Amino-2'-deoxyadenosine

Cat.No: T40556

7-Deaza-2'-deoxy-7-iodoadenosine

Cat.No: T39141

Cat.No: T38554

Synonym: 依特立生；依特普森,AVI 4658

Mipomersen sodium

Cat.No: T40727

DMT-dC(ac) Phosphoramidite

Cat.No: T36753

5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT

Cat.No: T83297

Cat.No: T39166

Synonym: IONIS-HTTRx,RG6042

Cat.No: T38464

Synonym: SPC-3649,Miravirsen

Cat.No: T76238

Inotersen sodium

Cat.No: T38909

Synonym: ISIS-420915 sodium

Aprinocarsen sodium

Cat.No: T74691

Apatorsen sodium

Cat.No: T74433

Cat.No: T39455

Synonym: NS-065,NCNP-01

Cat.No: T39712

Synonym: RG4326,RGLS4326

DBCO-PEG4-TAMRA

Cat.No: T15074

Target: Others

Cat.No: T39650

Synonym: IONIS-C9Rx,BIIB078

Cat.No: TD0070

Synonym: [6-Carboxy-X-rhodamine, succinimidyl ester] *Single isomer*,6-羧基-X-罗丹明琥珀酰亚胺酯（单一化合物）

Cat.No: T75153

Cat.No: T39498

Synonym: BIIB067,ISIS-SOD1Rx

Cat.No: T39294

Synonym: MRG-106,Cobomarsen

Cat.No: T74250

5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)

Cat.No: T74704

Cat.No: T39347

Cat.No: T74842

Decamethylene glycol

Cat.No: T21096

Synonym: alpha,omega-Decanediol,Decamethylenediol,1,10-Dihydroxydecane,Decane-1,10-diol

Cat. No.	Product Name	Target	Signaling Pathways
T5888	5-Methoxysalicylic acid 5-MeOSA,5-甲氧基水杨酸	Others	Others
	5-Methoxysalicylic acid (5-MeOSA) 是一种天然产物。它同精胺联用后，是低聚核苷酸 MALDI 质谱分析的有效基质。
T1104	Paromomycin Sulfate Aminosidine sulfate,Paromomycin sulfate salt,硫酸巴龙霉素,巴龙霉素硫酸盐	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Paromomycin Sulfate (Aminosidine sulfate) 是一种广谱氨基糖苷类抗生素，是具有杀螨杀菌作用的新霉素衍生物。它通过与细菌 30S 核糖体 A 位点的 RNA 寡核苷酸特异性结合，使 mRNA 的翻译提前终止，并抑制蛋白质合成。它可研究细菌和寄生虫感染。

天然产物

5-Methoxysalicylic acid

Cat.No: T5888

Synonym: 5-MeOSA,5-甲氧基水杨酸

Target: Others

Paromomycin Sulfate

Cat.No: T1104

Synonym: Aminosidine sulfate,Paromomycin sulfate salt,硫酸巴龙霉素,巴龙霉素硫酸盐

Target: Antibacterial, Antibiotic, Parasite

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼