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Cat. No. | Product Name | Target | Signaling Pathways |
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T50028 |
6-fluoro-3-(4-1,2,5,6-tetrahydropyridyl)indole
6-氟-3-(1,2,3,6-四氢吡啶-4-基)-1H-吲哚,6-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole |
Others | Others |
6-fluoro-3-(4-1,2,5,6-tetrahydropyridyl)indole (6-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) 是一种吲哚衍生物,具有潜在抗癌活性,是开发新药的潜在先导化合物。 | |||
T3465L |
Vesnarinone HCl
Synonym 2,OPC-8212 HCl,Vesnarinone HCl(81840-15-5 Free base) |
Potassium Channel; Calcium Channel; PDE | Membrane transporter/Ion channel; Metabolism |
Vesnarinone HCl (OPC-8212 HCl) 是一种具有口服活性的 phosphodiesterase 3 (PDE3) 抑制剂。Vesnarinone HCl 可对钙离子和钾离子进行调节, 增加钙通量,减少钾通量。Vesnarinone HCl 是一种新的正性肌力化合物,可增强心肌收缩力,可用于心力衰竭的研究。 | |||
T3295 |
1-Methyl-1H-pyrazol-3-amine
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Others | Others |
1-Methyl-1H-pyrazol-3-amine 是一种吡唑类化合物。它已被用于合成各种化合物,如药物、染料和聚合物。它也是合成某些药物的重要中间体。它还被用于新药的开发,以及酶抑制剂和受体调节剂的研究。 | |||
T8826 |
3-AMINO-1,2,4-TRIAZINE
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Others | Others |
3-AMINO-1,2,4-TRIAZINE 是一种芳香族生物活性化合物,已用于合成各种药物,包括抗真菌药物氟康唑、抗炎药物布洛芬和抗癌药物紫杉醇;也被用于设计新药,如抗艾滋病药物齐多夫定和抗疟疾药物青蒿素;以及用于合成各种其他化合物,如抗糖尿病药物二甲双胍和抗高血压药物赖诺普利。 | |||
T14296 | Antitumor agent-3 | Others | Others |
Antitumor agent-3 is a potent compound. It comprises a new imidazopyridine having excellent antitumor activity as an active ingredient. | |||
T60925 |
TRβ agonist 3
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TRβ agonist 3 (Compound 3) 是TRβ的有效激动剂,它是一种新的潜在 TRβ 选择性拟甲状腺素。在体外研究中,TRβ agonist 3 可减少 HepG2 中的脂质积累并促进脂肪分解。 | |||
T60282 |
Metallo-β-lactamase-IN-3
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Metallo-β-lactamase-IN-3 (compound 35) 是一种有效的金属 -β- 内酰胺酶 (MBL) 抑制剂,具有恢复现有 β-内酰胺类抗生素活性的潜力并为新抗生素的发现提供正交策略。Metallo-β-lactamase-IN-3 对 VIM-1和 NDM-1的活性较高,其 IC50值分别为 0.6 和 1.0 μM。Metallo-β-lactamase-IN-3 对 IMP-7 无抑制作用。 | |||
T71230 |
VMY-1-103
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VMY-1-103 is a potent CDK inhibitor, is also a novel dansylated analog of purvalanol B, was shown to inhibit cell cycle progression and proliferation in prostate and breast cancer cells more effectively than purvalanol B. VMY-1-103 , but not purvalanol B, significantly decreased the proportion of cells in S phase and increased the proportion of cells in G(2)/M. VMY-1-103 increased the sub G(1) fraction of apoptotic cells, induced PARP and caspase-3 cleavage and increased the levels of the Death ... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN6410 |
New compound 3
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New compound 3 可用于生命科学领域的相关研究,其产品编号为 TN6410。 | |||
T5S1988 |
Isorhamnetin-3-O-glucoside
Isorhamnetin-3-O-beta-D-Glucoside,异鼠李素-3-O-葡萄糖苷 |
Others | Others |
Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) 是一种天然化合物,广泛存在于蔬菜和水稻中,经消化后可在肠道菌群中代谢。 | |||
T4S21320 |
ISOGINKGETIN
异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮 |
MMP; Others | Others; Proteases/Proteasome |
ISOGINKGETIN (4',4'''-Dimethylamentoflavone) 是一种MMP9抑制剂,也是一种Pre-mRNA Splicing 抑制剂。 | |||
TN3218 |
7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one
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Beta Amyloid; PI3K; mTOR | Neuroscience; PI3K/Akt/mTOR signaling |
7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may provide new insights on drug discovery of Alzheimer's disease (AD). | |||
T37690 |
Phenylpyropene A
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Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3 |1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of ... |