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Cat. No. Product Name Target Signaling Pathways
T14489 Azvudine

4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮,FNC,RO-0622

HCV Protease; HBV; HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
Azvudine (FNC) 是一种有效的核苷逆转录酶抑制剂 (NRTI),对 HIV、HBV 和 HCV 具有抗病毒活性。它抑制耐 NRTI 的病毒株,高效抑制 HIV-1和 HIV-2。
T78737 NNRTIs-IN-3

HIV Protease Microbiology/Virology; Proteases/Proteasome
NNRTIs-IN-3(化合物8)作为一种HIV-1非核苷逆转录酶抑制剂,表现出较高的效力(EC50=0.01 µM)。
T78948 NNRTIs-IN-1

NNRTIs-IN-1是一种非核苷逆转录酶抑制剂, 对野生型HIV-1及五种突变株表现出有效抑制作用, 其EC50值处于纳摩尔量级。该化合物同时展现出优良的药代动力学性质, 并具备显著的抗抗药性特点。
T0110 Zalcitabine

Dideoxycytidine,ddC,扎西他滨,NSC 606170,Ro 24-2027/000,2',3'-Dideoxycytidine

HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
Zalcitabine (Dideoxycytidine) 是一种核苷类似物逆转录酶抑制剂,用于HIV 感染相关研究。
T2409 Tenofovir alafenamide

替诺福韦艾拉酚胺,替诺福韦,GS-7340

HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
Tenofovir alafenamide (GS-7340) 是一种核苷酸逆转录酶抑制剂和抗逆转录病毒替诺福韦的新型酯类前药。
T2279 Tizoxanide

替唑尼特,Desacetyl-nitazoxanide,TIZ

Antiviral; HIV Protease; Antibacterial; Autophagy Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Tizoxanide (Desacetyl-nitazoxanide) 是 Nitazoxanide 活性代谢物,有抗HIV-1的活性。Nitazoxanide 可抗细菌和多种病毒复制。
T6214 Emtricitabine

恩曲他滨,FTC,Emtriva,BW1592

HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
Emtricitabine (FTC) 是一种核苷逆转录酶抑制剂, 在 PBMC 细胞中的 EC50值为0.01 µM,可研究 HIV 感染。
T38727 Azvudine hydrochloride

RO-0622 hydrochloride,Azvudine hydrochloride,FNChydrochloride

Azvudine hydrochloride (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI) that exhibits strong antiviral effects against HIV, HBV, and HCV. It demonstrates highly potent inhibition of HIV-1 (EC 50 ranging from 0.03 to 6.92 nM) and HIV-2 (EC 50 ranging from 0.018 to 0.025 nM). Additionally, Azvudine hydrochloride effectively inhibits NRTI-resistant viral strains.
T61427 Lamivudine salicylate

Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI) that effectively inhibits the reverse transcriptase activity of both HIV 1/2 and hepatitis B virus. Moreover, it demonstrates the ability to penetrate the central nervous system [1] [2].
T60356 Stavudine sodium

Stavudine (d4T) sodium 是一种口服活性核苷逆转录酶抑制剂 (NRTI), 具有抗HIV-1和HIV-2的活性。Stavudine sodium 还抑制线粒体 DNA (mtDNA) 的复制。Stavudine sodium 降低 NLRP3 炎症小体激活并调节淀粉样 β 自噬。Stavudine sodium 诱导细胞凋亡。
T71983 Zidovudine glucuronide

Zidovudine glucuronide is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
T71518 Zidovudine diphosphate

Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
T71241 Carbovir

Carbovir, also known as (-)-Carbovir, is a nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) caused mitochondrial toxicity in human hepatoma carcinoma cell.
T40120 FNC-TP

FNC-TP, the intracellular active form of FNC, is a potent nucleoside reverse transcriptase inhibitor (NRTI) with broad-spectrum antiviral activity against HIV, HBV, and HCV.
T14488 Azt-pmap

HIV Protease Microbiology/Virology; Proteases/Proteasome
AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1]. As a nucleoside reverse transcriptase inhibitor (NRTI), AZT-PMPA targets HIV infection effectively[2].
T64188 FNC-TP trisodium

FNC-TP trisodium 是 FNC 的细胞内活性形式。FNC 是一种核苷逆转录酶的有效抑制剂 (NRTI),对 HIV、HBV 和 HCV 表现出抗病毒作用。
T24839 Stampidine

HI-113,HI 113,HI113

Stampidine can prevent the sexual transmission of HIV-1. It exhibited remarkable subnanomolar to low nanomolar in vitro antiretroviral potency against nucleoside reverse transcriptase inhibitor-resistant primary clinical HIV isolates, non-nucleoside RT-re

化合物

Azvudine
Cat.No: T14489
Synonym: 4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮,FNC,RO-0622
Target: HCV Protease, HBV, HIV Protease, Reverse Transcriptase
NNRTIs-IN-3
Cat.No: T78737
Synonym:
Target: HIV Protease
NNRTIs-IN-1
Cat.No: T78948
Synonym:
Target:
Zalcitabine
Cat.No: T0110
Synonym: Dideoxycytidine,ddC,扎西他滨,NSC 606170,Ro 24-2027/000,2',3'-Dideoxycytidine
Target: HIV Protease, Reverse Transcriptase
Tenofovir alafenamide
Cat.No: T2409
Synonym: 替诺福韦艾拉酚胺,替诺福韦,GS-7340
Target: HIV Protease, Reverse Transcriptase
Tizoxanide
Cat.No: T2279
Synonym: 替唑尼特,Desacetyl-nitazoxanide,TIZ
Target: Antiviral, HIV Protease, Antibacterial, Autophagy
Emtricitabine
Cat.No: T6214
Synonym: 恩曲他滨,FTC,Emtriva,BW1592
Target: HIV Protease, Reverse Transcriptase
Azvudine hydrochloride
Cat.No: T38727
Synonym: RO-0622 hydrochloride,Azvudine hydrochloride,FNChydrochloride
Target:
Lamivudine salicylate
Cat.No: T61427
Synonym:
Target:
Stavudine sodium
Cat.No: T60356
Synonym:
Target:
Zidovudine glucuronide
Cat.No: T71983
Synonym:
Target:
Zidovudine diphosphate
Cat.No: T71518
Synonym:
Target:
Carbovir
Cat.No: T71241
Synonym:
Target:
FNC-TP
Cat.No: T40120
Synonym:
Target:
Azt-pmap
Cat.No: T14488
Synonym:
Target: HIV Protease
FNC-TP trisodium
Cat.No: T64188
Synonym:
Target:
Stampidine
Cat.No: T24839
Synonym: HI-113,HI 113,HI113
Target:
TargetMol Loading
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