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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22864 |
Immethridine dihydrobromide
|
Others | Others |
Immethridine dihydrobromide is a histamine H3 receptor agonist. | |||
T6801 |
CeMMEC13
|
Carboxypeptidase; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome |
CeMMEC13 是一种异喹啉酮,可选择性抑制 TAF1 的第二个溴结构域,IC50为 2.1 μM。 | |||
T4345 |
CeMMEC1
CeMMEC1 HCl |
Epigenetic Reader Domain; Carboxypeptidase; DNA/RNA Synthesis | Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome |
CeMMEC1 是一种 BRD4 抑制剂,对 TAF1 有很好的亲和力,IC50为0.9 μM。 | |||
T22863 |
Immepip dihydrobromide
|
Others | Others |
Immepip dihydrobromide is a histamine H3 receptor agonist. | |||
T73408 | Immepip | ||
Immepip 是一种 H3激动剂。Immepip 可以减少皮质组胺的释放。Immepip 可用于神经系统疾病的研究。 | |||
T77799 |
CeMMEC1 HCl
|
||
CeMMEC1是一种衍生自N-methylisoquinolinone的化合物,具有抑制TAF1第二溴结构域的功能。 | |||
T26977 |
CeMMEC2
CeMMEC-2,CeMMEC 2 |
||
CeMMEC2, a novel inhibitor of BRD4, binds both the first and the second bromodomain of BRD4. | |||
T32019 |
Guanyl-damme
Guanyl damme |
||
Guanyl-damme is an analog of stable met-enkephalin. | |||
T16467 | Pentaethylene glycol monomethyl ether | Others | Others |
Pentaethylene glycol monomethyl ether (PEG-MME) is a PEG-based PROTAC linker, which is employed for the synthesis of PROTACs[1]. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7682 |
Asymmetric dimethylarginine
|
Endogenous Metabolite; NO Synthase; NOD | Immunology/Inflammation; Metabolism; NF-κB |
Asymmetric dimethylarginine 是内源性一氧化氮合成酶抑制剂,可以作为内皮功能障碍的标志。 | |||
T73068 | Mammea A/BA | ||
Mammea A/BA 对克氏锥虫 (T. cruzi) 显示出有效抗性。通过诱导线粒体功能障碍、产生活性氧 (ROS)、DNA 片段化以及增加酸性液泡数量,Mammea A/BA 触发细胞死亡机制,包括细胞凋亡 (apoptosis)、细胞自噬 (autophagy) 和细胞坏死,对于南美锥虫病的研究具有潜在应用价值。 | |||
T38331 |
Commendamide
|
||
Commendamide is a natural bacterial product that was discovered in a screen for commensal bacteria effector genes (Cbegs). Cbeg12 is a bacterial effector gene that encodes for its production. Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM. | |||
T33171 |
Mammeisin
|
||
Mammeisin is a constituent of Mammea americana. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02869 |
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptidase 12 |
Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... | |||
TMPJ-00942 |
MMP-12 Protein, Mouse, Recombinant (His)
Mme,Mmp12,MMP-12,Mmel,Matrix metalloprotei... |
Mouse | HEK293 Cells |
Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. | |||
TMPH-03691 |
VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc)
|
VSIV | E. coli |
Attaches the virus to host cellular receptor, inducing clathrin-dependent endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane. VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.8 kDa and the accession number is P0C2X0. |