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35

抑制剂 & 化合物

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天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T32948	Lumin
	Lumin is a cyanine dye that enhances interleukin 12-dependent interferon gamma production by lipopolysaccharide-stimulated mouse splenocytes.
T21428	Mianserin Lantanon,Lumin,Norval,Lerivon,Depnon	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Mianserin 是H1受体反向激动剂，是四环抗抑郁药(TeCA)治疗家族中的一种精神活性化合物，具有抗抑郁、抗焦虑、止吐、促氧、催眠和抗组胺作用，可作为去甲肾上腺素和特定的血清素联合用药能治疗抑郁症。
T18914	AkaLumine hydrochloride AkaLumine hydrochloride (1176235-08-7 free base),AkaLumine hydrochloride
	AkaLumine hydrochloride 是一种荧光素类似物，对重组荧光蛋白的 Km 值为 2.06 μM。
T1209	Flunixin meglumine Banamine,Finadyne,Flunixin meglumin,氟尼辛葡甲胺	COX	Immunology/Inflammation; Neuroscience
	Flunixin meglumine (Banamine) 是一种环氧合酶抑制剂，具有抗炎和解热活性。
T1790	Fosaprepitant dimeglumine 福沙匹坦二甲葡胺,L785298,福沙吡坦二甲葡胺,MK-0517,Fosaprepitant dimeglumine salt	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Fosaprepitant dimeglumine (MK-0517) 是 Aprepitant 的前药。它是一种神经激肽 1 受体拮抗剂，可用于预防化疗引起的恶心呕吐。
T8173	Delafloxacin meglumine ABT492 meglumine,德拉沙星葡甲胺,WQ-3034 meglumine,RX-3341 meglumine	Antibacterial; Antibiotic	Microbiology/Virology
	Delafloxacin meglumine (RX-3341 meglumine) 是一种广谱氟喹诺酮类抗生素。Delafloxacin 对耐药性的金黄色葡萄球菌，肺炎克雷伯菌和肺炎链球菌有活性。
T4506	Gadopentetate dimeglumine Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,钆喷酸葡胺,Gadopentetic acid dimeglumine salt	Others	Others
	Gadopentetate dimeglumine (Gd-DTPA) 可用于核磁共振成像 (MRI) 中，使血管、器官和其他非骨组织能够更清晰地被看到。
T19637	Aluminum phthalocyanine chloride Phthalocyanine Chloroaluminum,铝酞菁,Chloroaluminum Phthalocyanine	Others	Others
	Aluminum phthalocyanine chloride (Phthalocyanine Chloroaluminum) 是一种强烈的蓝绿色芳香大环化合物，广泛用于染色。
T13545	Aluminum Hydroxide	Others	Others
	Aluminum Hydroxide 是一种具有口服活性的铝佐剂的主要形式。它也可作为佐剂补偿亚单位疫苗的低固有免疫原性。基于它辅助的研究包括储存库效应、促吞噬作用和激活促炎症的 NLRP3 通路。
T0503	Meglumine Meglumin,Methylglucamin,葡甲胺,葡萄糖甲胺,Methylglucamine	Others	Others
	Meglumine (Meglumin) 是一种氨基糖，来源于山梨糖醇。其中常在药物中用作赋形剂，并与碘代化合物葡甲胺和碘帕胺葡甲胺等造影剂中的碘化化合物一起使用。
T35381	Aluminum potassium sulfate Potassium Aluminium Sulfate,APS	Others	Others
	Aluminum potassium sulfate (Potassium Aluminium Sulfate) 可用于研究严重急性呼吸系统综合症，可用于预防和治疗癌症。
T1989	Luminespib AUY922,VER-52296,NVP-AUY922	Apoptosis; HSP; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Metabolism
	Luminespib (VER-52296) 是一种 HSP90抑制剂，抑制 HSP90α 和 HSP90β 的 IC50分别为 7.8 和 21 nM。
T15792	Luminol 鲁米诺,Diogenes reagent	Others	Others
	Luminol (Diogenes reagent) 是化学发光物质，pKa 值为 6.74 和 15.1。它的最适荧光波长为 425 nm。它在刑事侦查、生物工程、化学示踪等领域中可用作法医检测血迹的诊断工具。
T20637	Diatrizoate meglumine Reno,Renografin,Renovist,泛影葡胺,Hypaque,Renocal,Sinografin	Others	Others
	Diatrizoate meglumine (Renocal) 是泛影酸盐的葡甲胺盐，它是一种有机的、碘化的、不透射线的 X 射线造影剂，用于放射诊断。
T7582	tafamidis meglumine Fx-1006A,他发米帝司甲葡胺	Others	Others
	Tafamidis meglumine (Fx-1006A) 是transthyretin (TTR)的选择性稳定剂，对野生型 WT-TTR 和突变型同源四聚体 V30M-TTR，V122I-TTR 的活性相当，EC50值为 2.7-3.2 μM。它能够阻碍淀粉样蛋白的生成。
T29237	(-)-Adlumine
	(-)-Adlumine is a bioactive chemical.
T64984	Aluminum Glycinate
	Aluminum Glycinate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64984，CAS号为 13682-92-3。
T35699	Fosetyl-aluminum
	0 [1]. Fan Z, Jia S, Ding N, et al. Determination of Fosetyl-Aluminium by Ion-Pair Reversed Phase-High Performance Liquid Chromatography With Evaporative Light Scattering Detection. Se Pu. 2009;27(6):849‐851. [2]. TüRK LMEZ , et al. Activity of metalaxyl-M+mancozeb, fosetyl-Al, and phosphorous acid against Phytophthora crown and root rot of apricot and cherry caused by Phytophthora palmivora. Plant Protect. Sci., 53: 216-225.
T33916	Pentagastrin meglumine
	Pentagastrin meglumine is a synthetic pentapeptide that has effects like gastrin when given parenterally.
T29922	Aluminum phthalocyanine disulfonate disodium AlPcS2,AlPcS(2a),Disulfonated aluminum phthalocyanine,ClAlPcS2. Clalpcs,AlS2Pc
	Aluminum phthalocyanine disulfonate sodium, also known as AlPcS2 disodium or AlS2Pc or AlPcS(2a), is a potent photosensitizer, and is potentially useful in cancer sonodynamic therapy and cancer photodynamic therapy. Aluminum phthalocyanine disulfonate is
T32168	Iodamide Meglumine Opacist E.R.,Meglumine iodamide,Iodamide 300,Renovue-65,Isteropac E.R.
	Iodamide Meglumine is a bioactive chemical.
T31344	Decanoic acid, aluminum salt Aluminum caprate,Decanoic acid,aluminum salt (3:1),Aluminum tridecanoate,aluminum salt
	Decanoic acid, aluminum salt is a biochemical.
T31753	Food Yellow No. 5 Aluminum Lake C.I. Food Yellow 4:1
	FD&C Yellow No. 5 Aluminum Lake is a synthetic lemon yellow azo dye primarily used as a food coloring.
T31423	Diazoluminolmelanin DALM
	Diazoluminolmelanin is a synthetic luminescent biopolymer.
T32949	Luminamicin
	Luminamicin is active against anaerobic bacteria, especially Clostridium sp.; isolated from actinomycete strain OMR-59.
T29796	AkaLumine Aka Lumine
	Akalumine is a luciferin anemone. When the bioluminescence produced in the reaction with natural firefly luciferase is obtained in the near-infrared wavelength range (λ Max =677 nm).
T74593	Taragarestrant meglumine
	Taragarestrant meglumine (D-0502) 是一种口服有效、选择性的雌激素受体 (estrogen receptor) 降解剂，展现了对各种ER+乳腺癌细胞系及移植模型的强大活性。
T126534	Caulophyllumine A
	Caulophyllumine A 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126534。
T21243	Aluminium clofibrate Atherolip,Alfibrate,Alufibrate
	Aluminium clofibrate, a salt of clofibric acid, is a peroxisome proliferator.
T30666	C.I. Food Blue 1-aluminum lake EINECS 240-589-3,Indigotine-aluminum lake,Acid Blue 74-aluminum lake,Pigment Blue 63
	C.I. Food Blue 1-aluminum lake is a type of colorant.
T32184	Iothalamate meglumine Cysto-Conray,Methylglucamine iotalamate,EINECS 235-998-9,Meglumine conray
	Iothalamate meglumine, known as radiopaque medium, can be used for urography, angiography, venography, and myelography. It is highly viscous and can bind to plasma proteins.
T29242	(+-)-Adlumine
	(+-)-Adlumine is a bioactive chemical.
T10391	Aspirin Aluminum Aluminum diacetylsalicylate,阿司匹林铝	Others	Others
	Aspirin Aluminum is an intermolecular compound that can inhibit gastrointestinal mucosal disorders induced by NSAIDs.
T13198	Transcrocetin meglumine salt trans-Crocetin meglumine salt	Others	Others
	Transcrocetin meglumine salt is a natural product isolated from saffron (Crocus sativus L.) and is a high-affinity antagonist of the NMDA receptor.
T68760	Luminespib mesylate
	Luminespib, also known as AUY-922, NVP-AUY922, VER52296, is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock protein 72 (Hsp72) in a wide range of human tumor cell lines.

化合物

Cat.No: T32948

Cat.No: T21428

Synonym: Lantanon,Lumin,Norval,Lerivon,Depnon

Target: Histamine Receptor

AkaLumine hydrochloride

Cat.No: T18914

Synonym: AkaLumine hydrochloride (1176235-08-7 free base),AkaLumine hydrochloride

Flunixin meglumine

Cat.No: T1209

Synonym: Banamine,Finadyne,Flunixin meglumin,氟尼辛葡甲胺

Target: COX

Fosaprepitant dimeglumine

Cat.No: T1790

Synonym: 福沙匹坦二甲葡胺,L785298,福沙吡坦二甲葡胺,MK-0517,Fosaprepitant dimeglumine salt

Target: Neurokinin receptor

Delafloxacin meglumine

Cat.No: T8173

Synonym: ABT492 meglumine,德拉沙星葡甲胺,WQ-3034 meglumine,RX-3341 meglumine

Target: Antibacterial, Antibiotic

Gadopentetate dimeglumine

Cat.No: T4506

Synonym: Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,钆喷酸葡胺,Gadopentetic acid dimeglumine salt

Target: Others

Aluminum phthalocyanine chloride

Cat.No: T19637

Synonym: Phthalocyanine Chloroaluminum,铝酞菁,Chloroaluminum Phthalocyanine

Target: Others

Aluminum Hydroxide

Cat.No: T13545

Target: Others

Cat.No: T0503

Synonym: Meglumin,Methylglucamin,葡甲胺,葡萄糖甲胺,Methylglucamine

Target: Others

Aluminum potassium sulfate

Cat.No: T35381

Synonym: Potassium Aluminium Sulfate,APS

Target: Others

Cat.No: T1989

Synonym: AUY922,VER-52296,NVP-AUY922

Target: Apoptosis, HSP, Autophagy

Cat.No: T15792

Synonym: 鲁米诺,Diogenes reagent

Target: Others

Diatrizoate meglumine

Cat.No: T20637

Synonym: Reno,Renografin,Renovist,泛影葡胺,Hypaque,Renocal,Sinografin

Target: Others

tafamidis meglumine

Cat.No: T7582

Synonym: Fx-1006A,他发米帝司甲葡胺

Target: Others

Cat.No: T29237

Aluminum Glycinate

Cat.No: T64984

Fosetyl-aluminum

Cat.No: T35699

Pentagastrin meglumine

Cat.No: T33916

Aluminum phthalocyanine disulfonate disodium

Cat.No: T29922

Synonym: AlPcS2,AlPcS(2a),Disulfonated aluminum phthalocyanine,ClAlPcS2. Clalpcs,AlS2Pc

Iodamide Meglumine

Cat.No: T32168

Synonym: Opacist E.R.,Meglumine iodamide,Iodamide 300,Renovue-65,Isteropac E.R.

Decanoic acid, aluminum salt

Cat.No: T31344

Synonym: Aluminum caprate,Decanoic acid,aluminum salt (3:1),Aluminum tridecanoate,aluminum salt

Food Yellow No. 5 Aluminum Lake

Cat.No: T31753

Synonym: C.I. Food Yellow 4:1

Diazoluminolmelanin

Cat.No: T31423

Synonym: DALM

Cat.No: T32949

Cat.No: T29796

Synonym: Aka Lumine

Taragarestrant meglumine

Cat.No: T74593

Caulophyllumine A

Cat.No: T126534

Aluminium clofibrate

Cat.No: T21243

Synonym: Atherolip,Alfibrate,Alufibrate

C.I. Food Blue 1-aluminum lake

Cat.No: T30666

Synonym: EINECS 240-589-3,Indigotine-aluminum lake,Acid Blue 74-aluminum lake,Pigment Blue 63

Iothalamate meglumine

Cat.No: T32184

Synonym: Cysto-Conray,Methylglucamine iotalamate,EINECS 235-998-9,Meglumine conray

Cat.No: T29242

Aspirin Aluminum

Cat.No: T10391

Synonym: Aluminum diacetylsalicylate,阿司匹林铝

Target: Others

Transcrocetin meglumine salt

Cat.No: T13198

Synonym: trans-Crocetin meglumine salt

Target: Others

Luminespib mesylate

Cat.No: T68760

Cat. No.	Product Name	Target	Signaling Pathways
T75267	Crocetin meglumine
	Crocetin (Transcrocetin) meglumine 从藏红花 (Crocus sativus L.) 中提取的，是一种高亲和力的 NMDA 受体拮抗剂。
TN3702	(-)-Corlumine	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Corlumine exhibits spasmolytic and GABA antagonist activity.

天然产物

Crocetin meglumine

Cat.No: T75267

Cat.No: TN3702

Target: GABA Receptor

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