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Search Results for " lrp "

Targets Recommended: NOD

28

抑制剂 & 化合物

3

天然产物

28

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T61132	NLRP3-IN-11	NOD	Immunology/Inflammation; NF-κB
	NLRP3-IN-11 是一种NLRP3蛋白抑制剂，具有潜在的抗炎活性。NLRP3-IN-11 可用于研究动脉粥样硬化、阿尔茨海默病和帕金森病类自身炎症性疾病炎症和退行性疾病。
T61392	NLRP3-IN-10 ZVN26391	NOD	Immunology/Inflammation; NF-κB
	NLRP3-IN-10 (ZVN26391) 是强效的 NLRP3 抑制剂，抑制 IL-1β 释放的 IC50 为 251.1 nM。NLRP3-IN-10 通过减弱 ASC 斑点形成来抑制 NLRP3炎症小体激活。
T60442	NLRP3/AIM2-IN-3	NOD; AIM2	Immunology/Inflammation; NF-κB
	NLRP3/AIM2-IN-3 是一种独特的分子，能以物种特异性的方式抑制 NLRP3 和 AIM2 炎性体的激活。它对细胞裂解的 IC50 值为 0.077 ± 0.008 μ M。NLRP3/AIM2-IN-3是一种 NLRP3 和 AIM2 炎症体依赖性细胞裂解的强效抑制剂，对细胞裂解的 IC50 值为 0.077 ± 0.008 μ M。NLRP3/AIM2-IN-3 可抑制 LPS/nigericin 刺激的 THP-1 巨噬细胞的细胞裂解，其 IC50 值为 0.077 ± 0.008 μM。NLRP3/AIM2-IN-3 干扰了 NLRP3 或 AIM2 与桥接蛋白 ASC 的相互作用，抑制了 ASC 的寡聚。
T3230	NLRP3-IN-2 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺,NLRP3 Inflammasome Inhibitor I	NOD-like Receptor (NLR); NOD	Immunology/Inflammation; NF-κB
	NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide) 是一种能够合成格列本脲的中间物，对心肌细胞中NLRP3炎症小体的形成具有抑制作用，在小鼠心肌缺血/再灌注后限制梗死面积，且对代谢无影响。
T28178	NLRP3-IN-9 INF-4E,INF 4E,INF4E	NOD	Immunology/Inflammation; NF-κB
	NLRP3-IN-9 (INF-4E) 是 NLRP3 ATPase 和 caspase-1 的抑制剂。 NLRP3-IN-9 通过不可逆地捕获硫醇亲核体发挥作用，以时间和浓度依赖性方式防止 ATP 和尼日利亚菌素触发的人 THP-1 细胞焦亡。
T60404	NLRP3/AIM2-IN-2	AIM2	Immunology/Inflammation
	NLRP3/AIM2-IN-2是一种新型强效抑制剂，对依赖于 NLRP3和 AIM2炎症体的热扩散具有不同物种特异性影响，IC50为0.2392 ± 0.0233 μ M。
T60756	NLRP3 antagonist 1
	NLRP3 antagonist 1 具有癌症疾病的研究潜力，是NLRP3的有效拮抗剂。NLRP3 参与机体对应激损伤和病原体感染的内在免疫，主要表达在巨噬细胞和中性粒细胞。
T78168	NLRP3-IN-17	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-17为一种高效、选择性且具有口服活性的NLRP3炎性体抑制剂，IC50为7 nM。该化合物在小鼠模型中显著抑制NLRP3依赖的IL-1β分泌，适用于慢性炎症疾病的研究。
T61826	NLRP3-IN-4
	NLRP3-IN-4 is a highly efficient and orally bioavailable inhibitor of NLRP3 inflammasome, which exhibits strong anti-inflammatory properties specifically targeted towards colitis.
T78894	NLRP3-IN-21	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-21（compound L38）是一款NLRP3炎症体抑制剂，具抗炎特性。此化合物能够抑制gasdermin D裂解、防止ASC寡聚化，并阻止NLRP3炎症小体的组装，从而遏制NLRP3炎症小体的激活及焦亡过程。
T73015	NLRP3-IN-16	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-16为高效、选择性NLRP3炎症小体抑制剂。其抑制IL-1β释放的IC50为0.131 μM，适用于炎症相关研究。
T79695	NLRP3-IN-19 NLRP3-IN-19	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-19（JT001）是一种高效、特异性且具有口服活性的NLRP3抑制剂，能够阻断NLRP3炎症小体的组装，抑制细胞因子释放，并预防细胞焦亡。该化合物适用于非酒精性脂肪性肝炎和肝纤维化研究。
T73014	NLRP3-IN-15
	NLRP3-IN-15 是一种有效的、选择性的 NLRP3炎症小体抑制剂 (KD: 5.87 μM)。NLRP3-IN-15 抑制 IL-1β 释放，IC50为 0.131 μM。NLRP3-IN-15可用于炎症研究。
T73018	NLRP3-IN-13
	NLRP3-IN-13 是一种有效的选择性NLRP3抑制剂 (IC50: 2.1 μM)。NLRP3-IN-13 抑制NLRP3和 NLRC4 炎性体，并抑制NLRP3介导的 IL-1β 产生。NLRP3-IN-13 还抑制NLRP3ATPase 活性。NLRP3-IN-13可用于神经炎症疾病的研究。
T81668	NLRP3 agonist 1	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3 agonist1 (compound 23)为高效口服活性NLRP3激动剂。该化合物能够激活Caspase-1酶，进而将pro-IL-1β与pro-IL-18等促炎细胞因子裂解为成熟型态。
T73013	NLRP3-IN-14
	NLRP3-IN-14 是一种有效的、选择性的 NLRP3炎症小体抑制剂 (KD: 5.87 μM)。NLRP3-IN-14 抑制 IL-1β 释放，IC50为 0.131 μM。NLRP3-IN-14可用于炎症研究。
T62809	NLRP3-IN-7
	NLRP3-IN-7 (Compound 36) 是一种 NLRP3炎性体的选择性抑制剂，能够 NLRP3 炎性体的组装。
T78180	NLRP3-IN-18	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-18（化合物13）是一种高效NLRP3抑制剂，其半抑制浓度（IC50）为1.0 µM或更低[1]。
T39607	NLRP3 modulators 1 NLRP3 modulators 1
	NLRP3 modulators 1 (WO2017184746A1, compound 107) is a potent modulator of NLRP3, capable of agonizing or partially agonizing the activity of NLRP3. This compound proves valuable in investigating conditions, diseases, or disorders where a reduction in LRP3 activity plays a role in the pathology.
T73034	NLRP3-IN-12
	NLRP3-IN-12 是一种特异性的 NLRP3炎症小体抑制剂。NLRP3-IN-12 通过靶向 NLRP3蛋白抑制 IL-1β 的释放，IC50值为 0.45 μM。NLRP3-IN-12 可用于研究炎症性肠病。
T39552	NLRP3-IN-5 NLRP3-IN-5
	NLRP3-IN-5, a compound disclosed in WO2016131098, is an inhibitor of NLRP3 inflammasome. It consists of the chemical structure N-((4-chloro-2,6-dimethylphenyl)carbamoyl)-4-(2-hydroxypropan-2-l)furan-2-sulfonamide.
T81665	NLRP3-IN-23	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-23 (Compound 15C) 是 NLRP3 炎症体激发的抑制剂，特别针对血红素介导机制。该化合物在 0.1μM 浓度时能显著抑制血红素诱导的 NLRP3 炎症体激活。
T81667	NLRP3 agonist 2	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3 agonist2（compound 22）为口服有效的NLRP3激动剂，能在THP1细胞内激活Caspase-1。
T62808	NLRP3-IN-6
	NLRP3-IN-6 (Compound 34) 是一种 NLRP3 炎性体的选择性抑制剂。
T81666	NLRP3-IN-22	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-22 (Compound II-4) 作为NLRP3抑制剂，展现出在10 μM浓度下67%的抑制效果。
T60563	NLRP3/AIM2-IN-1
	NLRP3/AIM2-IN-1是热脓毒症的抑制剂(IC50 = 3.136 ± 0.7667 μM)，显示出适度的反热光活性。
T79733	NLRP3-IN-20	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-20（compound 11）是一款口服活性的NLRP3炎症小体抑制剂，其抑制IL-1β分泌的IC50值为25 nM。该化合物展现出卓越的药代动力学性质，并在非酒精性脂肪性肝炎、致命性感染性休克以及结肠炎模型中证明了其显著疗效。
T62221	NLRP3-IN-8
	NLRP3-IN-8 (compound 27) 是具有口服活性的、与 NLRP3直接结合的 NLRP3炎性体抑制剂，对 IL-1β 的 IC50值为1.23 μM. NLRP3-IN-8 对肝微粒体具有良好的代谢稳定性 (t1/2= 138.63 min)，几乎没有毒性 (against L02: IC50> 100 μM) 。

化合物

Cat.No: T61132

Target: NOD

Cat.No: T61392

Synonym: ZVN26391

Target: NOD

NLRP3/AIM2-IN-3

Cat.No: T60442

Target: NOD, AIM2

Cat.No: T3230

Synonym: 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺,NLRP3 Inflammasome Inhibitor I

Target: NOD-like Receptor (NLR), NOD

Cat.No: T28178

Synonym: INF-4E,INF 4E,INF4E

Target: NOD

NLRP3/AIM2-IN-2

Cat.No: T60404

Target: AIM2

NLRP3 antagonist 1

Cat.No: T60756

Cat.No: T78168

Target: NOD-like Receptor (NLR)

Cat.No: T61826

Cat.No: T78894

Target: NOD-like Receptor (NLR)

Cat.No: T73015

Target: NOD-like Receptor (NLR)

Cat.No: T79695

Synonym: NLRP3-IN-19

Target: NOD-like Receptor (NLR)

Cat.No: T73014

Cat.No: T73018

NLRP3 agonist 1

Cat.No: T81668

Target: NOD-like Receptor (NLR)

Cat.No: T73013

Cat.No: T62809

Cat.No: T78180

Target: NOD-like Receptor (NLR)

NLRP3 modulators 1

Cat.No: T39607

Synonym: NLRP3 modulators 1

Cat.No: T73034

Cat.No: T39552

Synonym: NLRP3-IN-5

Cat.No: T81665

Target: NOD-like Receptor (NLR)

NLRP3 agonist 2

Cat.No: T81667

Target: NOD-like Receptor (NLR)

Cat.No: T62808

Cat.No: T81666

Target: NOD-like Receptor (NLR)

NLRP3/AIM2-IN-1

Cat.No: T60563

Cat.No: T79733

Target: NOD-like Receptor (NLR)

Cat.No: T62221

Cat. No.	Product Name	Target	Signaling Pathways
T2S0265	Robinin NSC 9222,刺槐素	TLR	Immunology/Inflammation
	Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin (NSC-9222) was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry.
T5214	Cholesteryl linoleate CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester,胆甾烯基亚油酸酯	Others; Endogenous Metabolite	Metabolism; Others
	Cholesteryl linoleate (Linoleic Acid cholesteryl ester) 是低密度脂蛋白和动脉粥样硬化病变中主要的胆固醇酯。它存在于 LDL 中的胆固醇酯，利用 LDL 受体相关蛋白转移到表达 15-脂氧合酶的巨噬细胞和 CHO 细胞的质膜，被氧化形成胆固醇亚油酸氢过氧化物。
TQ0215	Salinomycin sodium salt 盐霉素钠,Sodium salinomycin,Salinomycin sodium	Apoptosis; Wnt/beta-catenin; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Stem Cells
	Salinomycin sodium salt (Sodium salinomycin) 是钾离子载体抗生素，是作用于 Wnt/Fzd/LRP 复合物的Wnt/β-catenin 信号传导抑制剂，能阻断 Wnt 诱导的 LRP6 磷酸化，导致 LRP6 蛋白降解。它选择性抑制人肿瘤干细胞。

天然产物

Cat.No: T2S0265

Synonym: NSC 9222,刺槐素

Target: TLR

Cholesteryl linoleate

Cat.No: T5214

Synonym: CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester,胆甾烯基亚油酸酯

Target: Others, Endogenous Metabolite

Salinomycin sodium salt

Cat.No: TQ0215

Synonym: 盐霉素钠,Sodium salinomycin,Salinomycin sodium

Target: Apoptosis, Wnt/beta-catenin, Antibacterial, Antibiotic, Autophagy

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01063	LRP-10 Protein, Mouse, Recombinant (His) Lrp10,LRP-10,Lrp9	Mouse	HEK293 Cells
	LDL receptor-related protein (LRP) 10 was recently identified as a Parkinson's disease gene through genome-wide linkage and sequencing analysis, but its role in Parkinson's disease in various populations is still unclear.
TMPK-00744	LRP-6 Protein, Human, Recombinant (mFc) DCAD2,LRP-6,FLJ90421,LRP6,FLJ90062	Human	HEK293 Cells
	Dickkopf-related protein 1 (DKK-1), a ligand for the WNT coreceptors low-density lipoprotein receptor-related proteins 5 and 6 (LRP-5 and LRP-6) and an inhibitor of WNT/β-catenin signaling, effectively inhibits pericyte activation, detachment, and transition to myofibroblasts in vivo in response to kidney injury, resulting in attenuated fibrogenesis, capillary rarefaction, and inflammation.LRP-6 interacts closely with PDGF receptor β and TGF-β receptor 1 at the cell membrane, suggesting that it ...
TMPK-00740	LRP-5 Protein, Human, Recombinant (mFc) LRP7,EVR1,LR3VBCH2,HBM,LRP5,EVR4,VBCH2,OPS...	Human	HEK293 Cells
	A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass. Subsequent studies of LRP5 and sclerostin have provided important insights into the mechanisms by which these proteins regulate skeletal homeostasis. LRP-5 Protein, Human, Recomb...
TMPK-00739	LRP-5 Protein, Human, Recombinant (hFc) EVR1,BMND1,BMND1OPTA1,LRP5,LRP7,OPPG,EVR4,...	Human	HEK293 Cells
	A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass. Subsequent studies of LRP5 and sclerostin have provided important insights into the mechanisms by which these proteins regulate skeletal homeostasis. LRP-5 Protein, Human, Recomb...
TMPY-06639	LRP-5 Protein, Human, Recombinant (His) OPS,HBM,EVR1,BMND1,EVR4,OPTA1,LRP7,VBCH2,OPPG,LR3,L...	Human	HEK293 Cells
	LRP-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.21 kDa and the accession number is O75197-1.
TMPJ-01412	LRP-12 Protein, Human, Recombinant (His) LRP-12,ST7,Suppressor of Tumorigenicity 7 Protein,<...	Human	HEK293 Cells
	Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as ...
TMPY-02653	LRP-10 Protein, Human, Recombinant (hFc) low density lipoprotein receptor-related protein 10,MST087,M...	Human	HEK293 Cells
	LRP-10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73 kDa and the accession number is Q7Z4F1-1.
TMPY-02748	LRP-10 Protein, Human, Recombinant (His) MST087,LRP9,low density lipoprotein receptor-relate...	Human	HEK293 Cells
	LRP-10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.5kDa and the accession number is Q7Z4F1-1.
TMPY-03975	LRP-11 Protein, Human, Recombinant (His) MANSC3,bA350J20.3,low density lipoprotein receptor-related p...	Human	HEK293 Cells
	LRP-11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is Q86VZ4-1.
TMPY-06698	LRP-6 Protein, Human, Recombinant (His) LDL receptor related protein 6,ADCAD2	Human	HEK293 Cells
	LRP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.41 kDa and the accession number is O75581-1.
TMPY-06834	LRP-6 Protein, Human, Recombinant (hFc) LDL receptor related protein 6,ADCAD2	Human	HEK293 Cells
	LRP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.69 kDa and the accession number is O75581.
TMPY-02511	PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST) LRP,PTP α/PTPRA Protein, Human, Recombinant (aa 174...	Human	Baculovirus Insect Cells
	PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTPRA could promote the cell cycle progression through stimulating the c-Src signaling pathways. The PTPRA gene, which encodes the protein RPTP-alpha, is critical to neurodevelopment. Previous linkage studies, genome-wide association studies, controlled expression analyses and anima...
TMPY-00088	LRRC3B Protein, Human, Recombinant (His) leucine rich repeat containing 3B,LRP15	Human	HEK293 Cells
	LRRC3B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is A1LNH5.
TMPY-00353	LRRC3B Protein, Human, Recombinant (hFc) LRP15,leucine rich repeat containing 3B	Human	HEK293 Cells
	LRRC3B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is A1LNH5.
TMPY-02883	C1D Protein, Human, Recombinant (GST) SUNCOR,Rrp47,SUN-CoR,hC1D,C1D nuclear receptor corepressor,<...	Human	E. coli
	C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to m...
TMPH-01616	LRP2 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	LRP2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50.8 kDa and the accession number is P98164.
TMPH-01738	NLRP1 Protein, Human, Recombinant (GST)	Human	E. coli
	NLRP1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.9 kDa and the accession number is Q9C000.
TMPY-01732	LRPAP1 Protein, Mouse, Recombinant (His) C77774,AU042172,RAP,AI790446,low density lipoprotein recepto...	Mouse	HEK293 Cells
	LRPAP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.4 kDa and the accession number is P55302.
TMPH-01739	NLRP3 Protein, Human, Recombinant (His)	Human	E. coli
	NLRP3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.7 kDa and the accession number is Q96P20.
TMPY-01233	LRPAP1 Protein, Human, Recombinant (His) HBP44,MYP23,low density lipoprotein receptor-related protein...	Human	HEK293 Cells
	LRPAP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is P30533.
TMPH-02796	NLRP3 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	NLRP3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 34.2 kDa and the accession number is Q8R4B8.
TMPH-02502	LRPAP1 Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus Insect Cells
	Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. LRPAP1 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is P55302.
TMPY-03182	PLRP2 Protein, Human, Recombinant (His) PLRP2,pancreatic lipase-related protein 2	Human	Baculovirus Insect Cells
	Galactolipase, also known as PNLIPRP2, is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on monoglycerides, phospholipids and galactolipids. It also hydrolyses milk fat with a lower catalytic efficiency. The expressed galactolipase shows a lipolytic activity that is, however, only marginally dependent on the presence of colipase. The lipolytic activity of pancreatic extracts and human pancreatic juice on Labraso...
TMPY-01085	VLDLR Protein, Human, Recombinant (His) VLDLRCH,CAMRQ1,CHRMQ1,very low density lipoprotein receptor,...	Human	HEK293 Cells
	The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ...
TMPJ-00354	FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc) Frizzled-1,mFz1,Fzd1,Fz-1,Frizzled homolog 1	Mouse	HEK293 Cells
	Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.
TMPK-01155	MANSC1 Protein, Mouse, Recombinant (His) MANSC1,LOH12CR3,9130403P13Rik	Mouse	HEK293 Cells
	MANSC1 contains 1 MANSC domain. MANSC is a seven-cysteine-containing domain present in animal membrane and extracellular proteins. MANSC (motif at N terminus with seven cysteines) is a novel domain with a well-conserved seven-cysteine motif that is present at the N terminus of membrane and extracellular proteins, including low-density lipoprotein receptor-related protein 11 (LRP-11), hepatocyte growth factor activator inhibitor 1 (HAI-1) and some uncharacterized proteins encoded by multicellular...
TMPY-04422	Casein Kinase 1 gamma 2 Protein, Human, Recombinant (His) CK1g2,casein kinase 1, γ2,casein kinase 1, gamma 2,Casein Ki...	Human	Baculovirus Insect Cells
	Casein kinase I gamma 2 isoform (CSNK1G2), a member of the large casein kinase I (CKI) subfamily, protein kinase superfamily. It may affect the development of brain, and associate with vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. The CKI family includes several other isoforms (alpha, beta, gamma, and delta). Dishevelled (Dsh), another positive component of the Wnt pathway, becomes phosphorylated in response to Wnt signals. All the CKI isoforms, with the exce...
TMPY-01451	MESDC2 Protein, Human, Recombinant (His) MESD,mesoderm development candidate 2,BOCA	Human	HEK293 Cells
	MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity reside...

重组蛋白

LRP-10 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01063

Species: Mouse

Expression System: HEK293 Cells

LRP-6 Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00744

Species: Human

Expression System: HEK293 Cells

LRP-5 Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00740

Species: Human

Expression System: HEK293 Cells

LRP-5 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00739

Species: Human

Expression System: HEK293 Cells

LRP-5 Protein, Human, Recombinant (His)

Cat.No: TMPY-06639

Species: Human

Expression System: HEK293 Cells

LRP-12 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01412

Species: Human

Expression System: HEK293 Cells

LRP-10 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02653

Species: Human

Expression System: HEK293 Cells

LRP-10 Protein, Human, Recombinant (His)

Cat.No: TMPY-02748

Species: Human

Expression System: HEK293 Cells

LRP-11 Protein, Human, Recombinant (His)

Cat.No: TMPY-03975

Species: Human

Expression System: HEK293 Cells

LRP-6 Protein, Human, Recombinant (His)

Cat.No: TMPY-06698

Species: Human

Expression System: HEK293 Cells

LRP-6 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06834

Species: Human

Expression System: HEK293 Cells

PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)

Cat.No: TMPY-02511

Species: Human

Expression System: Baculovirus Insect Cells

LRRC3B Protein, Human, Recombinant (His)

Cat.No: TMPY-00088

Species: Human

Expression System: HEK293 Cells

LRRC3B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00353

Species: Human

Expression System: HEK293 Cells

C1D Protein, Human, Recombinant (GST)

Cat.No: TMPY-02883

Species: Human

Expression System: E. coli

LRP2 Protein, Human, Recombinant (mFc)

Cat.No: TMPH-01616

Species: Human

Expression System: HEK293 Cells

NLRP1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01738

Species: Human

Expression System: E. coli

LRPAP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01732

Species: Mouse

Expression System: HEK293 Cells

NLRP3 Protein, Human, Recombinant (His)

Cat.No: TMPH-01739

Species: Human

Expression System: E. coli

LRPAP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01233

Species: Human

Expression System: HEK293 Cells

NLRP3 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02796

Species: Mouse

Expression System: E. coli

LRPAP1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02502

Species: Mouse

Expression System: Baculovirus Insect Cells

PLRP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03182

Species: Human

Expression System: Baculovirus Insect Cells

VLDLR Protein, Human, Recombinant (His)

Cat.No: TMPY-01085

Species: Human

Expression System: HEK293 Cells

FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00354

Species: Mouse

Expression System: HEK293 Cells

MANSC1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01155

Species: Mouse

Expression System: HEK293 Cells

Casein Kinase 1 gamma 2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04422

Species: Human

Expression System: Baculovirus Insect Cells

MESDC2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01451

Species: Human

Expression System: HEK293 Cells

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