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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T63992 KS100

KS100 是 ALDH 的有效抑制剂，能够作用于 ALDH1A1 (IC50: 334 nM)、ALDH2 (IC50: 2137 nM) 和 ALDH3A1 (IC50: 360 nM)。KS100 能够明显提高 ROS 活性、脂质过氧化和有毒醛的积累，且具有低毒性的抗增殖和抗癌活性。KS100 能够将细胞周期阻滞在 G2/M 期，并诱导细胞凋亡 (apoptosis)。
T3581 KS176

Potassium Channel; BCRP Membrane transporter/Ion channel
KS176是选择性高活性乳腺癌耐药蛋白多药转运通道抑制剂，在Pheo A 和Hoechst 检测中，IC50值分别为0.59和1.39 μM。
T63081 KS106

KS106 是一种 ALDH 的有效抑制剂，能够作用于 ALDH1A1 (IC50: 334 nM)、ALDH2 (IC50: 2137 nM) 和 ALDH3A1 (IC50: 360 nM)。KS106 具有抗增殖和抗癌作用，且毒性较低。KS106 可将细胞周期阻滞在G2/M 期，饼诱导细胞凋亡。KS106 能够明显提高 ROS 活性、脂质过氧化和有毒醛的积累。
T72437 PARP1/2/TNKS1/2-IN-1

Apoptosis; PARP; Wnt/beta-catenin Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
PARP1/2/TNKS1/2-IN-1 是一种多靶点抑制剂，抑制 PARP-1、PARP-2、TNKS1 和 TNKS2 。PARP1/2/TNKS1/2-IN-1 具有潜在的抗肿瘤活性，可诱导细胞凋亡。
T72922 TNKS1/2-IN-1

TNKS1/2-IN-1是一种针对tankyrase TNKS1/2的高效抑制剂，其pIC50值介于7.1至8.2之间。该化合物主要用于癌症、纤维化及其他高增殖性疾病的研究领域。
T27593 IKs124

IKs-124,IKs 124
IKs124 is a blocker of KCNE2 and KCNQ1 potassium channel.
T38433 KS15

KS15 is a chemical compound that acts as an inhibitor on the interactions between cryptochromes, specifically CRY1 and CRY2, and the CLOCK: BMAL1 heterodimer. This compound, with an EC50 value of 4.9 μM, hinders the feedback actions of CRYs on E-box-dependent transcription. The CLOCK: BMAL1 heterodimer is a vital transcriptional regulator for the mammalian circadian clock. In addition, KS15 exhibits significant anti-proliferative activity.

化合物

KS100
Cat.No: T63992
Synonym:
Target:
KS176
Cat.No: T3581
Synonym:
Target: Potassium Channel, BCRP
KS106
Cat.No: T63081
Synonym:
Target:
PARP1/2/TNKS1/2-IN-1
Cat.No: T72437
Synonym:
Target: Apoptosis, PARP, Wnt/beta-catenin
TNKS1/2-IN-1
Cat.No: T72922
Synonym:
Target:
IKs124
Cat.No: T27593
Synonym: IKs-124,IKs 124
Target:
KS15
Cat.No: T38433
Synonym:
Target:
Species：
Human (13)
Cynomolgus,Rhesus (2)
Mouse (1)
Expression System：
HEK293 Cells (12)
E. coli (4)
Tag：
C-His (4)
Tag Free (4)
C-hFc (3)
C-His-Avi (1)
C-hFc-Avi (1)
C-mFc (1)
His, Avi (1)
N-His (1)
Cat. No. Product Name Species Expression System
TMPY-01300 EpCAM/TROP1 Protein, Human, Recombinant (His)

TROP-1,ESA,EGP40,HNPCC8,EGP314,M4S1

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.84 kDa and the accession number is P16422.
TMPY-05587 EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated

HNPCC8,EGP314,KSA,KS1/4,...

 Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 30.7 kDa and the accession number is P16422.
TMPY-03781 CXCL14 Protein, Human, Recombinant

SCYB14,MIP-2g,MIP2G,KS1,BRAK,NJAC...

 Human E. coli
CXCL14 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is O95715.
TMPY-06582 CXCL14 Protein, Human, Recombinant (His)

SCYB14,BRAK,MIP2G,KS1,MIP-2g,chem...

 Human E. coli
CXCL14 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 11.51 kDa and the accession number is O95715.
TMPY-05618 CXCL14 Protein, Human, Recombinant, Biotinylated

MIP2G,BMAC,KS1,MIP-2g,chemokine (C-X-C mot...

 Human E. coli
CXCL14 Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is O95715.
TMPY-06849 EpCAM/TROP1 Protein, Human, Recombinant (mFc)

DIAR5,M4S1,EGP314,ESA,epithelial cell adhe...

 Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 53.81 kDa and the accession number is NP_002345.1.
TMPY-04953 EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated

M4S1,EGP-2,DIAR5,TROP1,TROP-1,HNP...

 Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is P16422.
TMPY-00785 EpCAM/TROP1 Protein, Human, Recombinant (hFc)

KSA,DIAR5,HNPCC8,TACSTD1,KS1<...

 Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54 kDa and the accession number is P16422.
TMPY-05117 EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated

EGP314,DIAR5,TACSTD1,MK-1,KS<...

 Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is P16422.
TMPY-05601 EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

MK-1,TROP1,EGP314,DIAR5,HNPCC8,TR...

 Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 56 kDa and the accession number is P16422.
TMPY-00001 CXCL14 Protein, Mouse, Recombinant

MIP2gamma,Scyb14,BMAC,MIP2γ,bolekine,AI414...

 Mouse E. coli
CXCL14 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is Q9WUQ5.
TMPK-00679 EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant

EpCAM,ACSTD1,ESA,MK1,EGP-2,EGP,MOC31

Cynomolgus,Rhesus HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.38 kDa and the accession number is Q1WER1.
TMPK-00207 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)

DIAR5,MOC31,EGP,MK1,HNPCC8,EGP314...

 Human HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.2 kDa and the accession number is P16422.
TMPK-00206 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)

ESA,TACSTD1,EGP-2,TROP1,EpCAM,EGP31

Human HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 54.2 kDa and the accession number is P16422.
TMPK-00680 EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

EGP40,EGP314,CD326,EGP,KSA,HNPCC8,ESA,DIAR...

 Cynomolgus,Rhesus HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.5 kDa and the accession number is Q1WER1.
TMPK-00205 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated

EGP40,TROP1,EGP314,MIC18,DIAR5,ES...

 Human HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P1...

重组蛋白

EpCAM/TROP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01300
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05587
Species: Human
Expression System: HEK293 Cells
CXCL14 Protein, Human, Recombinant
Cat.No: TMPY-03781
Species: Human
Expression System: E. coli
CXCL14 Protein, Human, Recombinant (His)
Cat.No: TMPY-06582
Species: Human
Expression System: E. coli
CXCL14 Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05618
Species: Human
Expression System: E. coli
EpCAM/TROP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-06849
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04953
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00785
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05117
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05601
Species: Human
Expression System: HEK293 Cells
CXCL14 Protein, Mouse, Recombinant
Cat.No: TMPY-00001
Species: Mouse
Expression System: E. coli
EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant
Cat.No: TMPK-00679
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)
Cat.No: TMPK-00207
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)
Cat.No: TMPK-00206
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00680
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated
Cat.No: TMPK-00205
Species: Human
Expression System: HEK293 Cells
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