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Search Results for " kat "

Targets Recommended: Histone Acetyltransferase

11

抑制剂 & 化合物

6

天然产物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T79131	KAT modulator-1	Histone Acetyltransferase	Chromatin/Epigenetic
	KAT modulator-1 (Compound 3)为一种KAT调节剂, 能够与全长p300进行相互作用，但不影响催化结构域。该化合物主要应用于表观遗传学研究领域。
T15644	KAT681 T0681	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	KAT681 is a liver selective thyromimetic.
T75146	KAT6-IN-1
	KAT6-IN-1 是一种有效的KAT6抑制剂。KAT6-IN-1可用于癌症研究。
TP1062L	Katacalcin acetate(85916-47-8 free base) PDN 21 acetate	Others	Others
	Katacalcin acetate(85916-47-8 free base) (PDN 21 acetate) 是一种有效的血浆降钙肽。
TP1061	Katacalcin TFA (85916-47-8 free base) PDN 21 (TFA),Katacalcin TFA
	Katacalcin TFA (PDN 21 TFA) a potent plasma calcium-lowering peptide.
T39093	TCTDSTNCYKAT
	TCTDSTNCYKAT is an engineered-variant peptide of antifreeze protein (AFP).
TP1062	Katacalcin 抗钙素,PDN 21
	Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide[1].
T78368	Katacalcin TFA PDN 21 TFA
	Katacalcin TFA (PDN 21 TFA)是一多肽激素，有效降低血钙水平。
T28368	PF-04859989 HCl PF 04859989,PF04859989,PF-04859989HCl,PF-04859989	Others	Others
	PF-04859989 HCl 是不可逆的犬尿氨酸转氨酶 KAT II 抑制剂，可透过血脑屏障，抑制 hKATⅡ 和 rKATⅡ 的 IC50分别为 23 和 263 nM。它对 KATⅡ 的选择性高于人 KATⅠ、KATⅢ 和 KATⅣ (IC50分别为22、11和 >50 μM)。
T24617	PF-04859989
	PF-04859989 is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II. PF-04859989 is ~1000-fold selective for KAT II over human KAT I, KAT III, and KAT IV. PF-04859989 has IC50 values of 23 nM for hKAT II and 263 nM for rKAT II.
T26785	BFF122 BFF 122,BF5,BFF-122
	BFF122 is an inhibitor of kynurenine aminotransferase II (KAT II).

化合物

KAT modulator-1

Cat.No: T79131

Target: Histone Acetyltransferase

Cat.No: T15644

Synonym: T0681

Target: Thyroid hormone receptor(THR)

Cat.No: T75146

Katacalcin acetate(85916-47-8 free base)

Cat.No: TP1062L

Synonym: PDN 21 acetate

Target: Others

Katacalcin TFA (85916-47-8 free base)

Cat.No: TP1061

Synonym: PDN 21 (TFA),Katacalcin TFA

Cat.No: T39093

Cat.No: TP1062

Synonym: 抗钙素,PDN 21

Katacalcin TFA

Cat.No: T78368

Synonym: PDN 21 TFA

PF-04859989 HCl

Cat.No: T28368

Synonym: PF 04859989,PF04859989,PF-04859989HCl,PF-04859989

Target: Others

Cat.No: T24617

Cat.No: T26785

Synonym: BFF 122,BF5,BFF-122

Cat. No.	Product Name	Target	Signaling Pathways
T3S0195	Nootkatone 诺卡酮,努特卡酮,诺卡酮	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Nootkatone 是一种神经保护剂，来自于Alpiniae OxyphyllaeFructus ，具有抗氧化和抗炎活性。它能够改善脂多糖诱导的阿尔茨海默氏病小鼠模型的认知障碍。
T5281	Skatole 粪臭素,Scatole,3-Methylindole,3-Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole	AhR; p38 MAPK; Aryl Hydrocarbon Receptor; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal	Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
	Skatole (3-Methyl-1H-indole) 是由肠道菌群产生的，通过激活芳基烃受体和 p38调节肠上皮细胞功能。
TN6229	Pukateine Pukatein
	Pukateine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6229，CAS号为 81-67-4。
T4415	Katacine	Others	Others
	Katacine 抑制氧气消耗，并抑制电子通过线粒体呼吸链从氧化底物转移到分子氧的速度。 Katacine 是来自蓼科蓼科蓼属的 A 型原花青素聚合物在不同聚合阶段的混合物。 Katacine 是一种抗缺氧药。
TN2931	3-Epikatonic acid	Antifection	Microbiology/Virology
	Epikatonic acid shows less active against T. (S.) cruzi trypanosome.
T4928	L-Kynurenine L-犬尿氨酸,(S)-Kynurenine	AhR; Aryl Hydrocarbon Receptor; Endogenous Metabolite	Immunology/Inflammation; Metabolism
	L-Kynurenine ((S)-Kynurenine) 是L-色氨酸的代谢物，是芳香烃受体激动剂，可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。

天然产物

Cat.No: T3S0195

Synonym: 诺卡酮,努特卡酮,诺卡酮

Target: AMPK

Cat.No: T5281

Synonym: 粪臭素,Scatole,3-Methylindole,3-Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole

Target: AhR, p38 MAPK, Aryl Hydrocarbon Receptor, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal

Cat.No: TN6229

Synonym: Pukatein

Cat.No: T4415

Target: Others

3-Epikatonic acid

Cat.No: TN2931

Target: Antifection

Cat.No: T4928

Synonym: L-犬尿氨酸,(S)-Kynurenine

Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01035	JAM-A Protein, Human, Recombinant (His) PAM-1,F11 receptor,JAMA,JAM1,KAT,CD321,JCAM,JAM	Human	HEK293 Cells
	JAM-A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q9Y624-1.
TMPY-00865	JAM-A Protein, Human, Recombinant (hFc) F11 receptor,JAM1,JAMA,KAT,CD321,JCAM,JAM,PAM-1	Human	HEK293 Cells
	JAM-A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50 kDa and the accession number is Q9BQB4-1.
TMPK-00188	JAM-A Protein, Mouse, Recombinant (His) F11R,JCAM1,PAM-1,PAM-1KAT,JAM-1,JAM,JCAM,JAM-A,...	Mouse	HEK293 Cells
	junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyon...
TMPH-01596	AADAT Protein, Human, Recombinant (His & SUMO) 2-aminoadipate transaminase,Glycine transaminase AADAT,Alpha...	Human	E. coli
	Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).
TMPH-03748	KAT14 Protein, Human, Recombinant (His)	Human	E. coli
	Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle.
TMPH-01470	KAT5 Protein, Human, Recombinant (His)	Human	E. coli
	KAT5 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-05906	Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H1N1	HEK293 Cells
	Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is A0A0U4T2C2.

重组蛋白

JAM-A Protein, Human, Recombinant (His)

Cat.No: TMPY-01035

Species: Human

Expression System: HEK293 Cells

JAM-A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00865

Species: Human

Expression System: HEK293 Cells

JAM-A Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00188

Species: Mouse

Expression System: HEK293 Cells

AADAT Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01596

Species: Human

Expression System: E. coli

KAT14 Protein, Human, Recombinant (His)

Cat.No: TMPH-03748

Species: Human

Expression System: E. coli

KAT5 Protein, Human, Recombinant (His)

Cat.No: TMPH-01470

Species: Human

Expression System: E. coli

Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-05906

Species: H1N1

Expression System: HEK293 Cells

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