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抑制剂 & 化合物

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天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T27794	λ-Cyhalothrin lambda-Cyhalothrin,Karate,λ-氯氟氰菊酯,Icon	Sodium Channel; Parasite	Membrane transporter/Ion channel; Microbiology/Virology
	λ-Cyhalothrin (Icon) 是广谱的 II 型合成除虫菊酯杀虫剂，含有 α-氰基，用于防治多种害虫。它是一种钠通道神经毒素，靶向中枢神经系统中神经元膜。
T20914	Simethicone Disflatyl,西甲硅油,Simeticone,Phazyme	Others	Others
	Simethicone (Disflatyl) 是一种口服消泡剂，可用于减少因胃或肠道内过多气体引起的腹胀、疼痛和不适。
T4985	Neticonazole Hydrochloride	Antifungal	Microbiology/Virology
	Neticonazole hydrochloride 是一种咪唑衍生物，具有抗感染和抗癌作用。它也是一种长效抗真菌剂。
T25982	Pramiconazole R-126638,R126638,R 126638,Azoline	Antifungal	Microbiology/Virology
	Pramiconazole (R126638) 是一种可口服的抗真菌化合物。Pramiconazole 是治疗皮肤癣菌和皮肤酵母菌感染的候选化合物，可用于治疗脂溢性皮炎。
T1290	Oxiconazole nitrate 硝酸奥昔康唑,Ro 13-8996	Others; Antibiotic; Antifection; Antifungal	Microbiology/Virology; Others
	Oxiconazole nitrate (Ro 13-8996) 是广谱抗真菌药物，抑制T. tonsurans 和T.rubrum 的生长，MIC90值分别为 0.25 和 0.5 μg/mL。
T2411	Luliconazole NND 502,卢立康唑	Antibiotic; Antifungal	Microbiology/Virology
	Luliconazole (NND 502) 是一种咪唑类抗生素，具有广谱抗真菌活性。它可研究皮肤感染。
T73586	Anticonvulsant agent 2	Others	Others
	Anticonvulsant agent 2 是一种有效的口服活性抗惊厥剂，在耐药性癫痫模型中显示出抗癫痫活性。
T7363	Ibuprofen Piconol U75630,匹美诺芬,布洛芬吡啶甲醇	Others	Others
	Ibuprofen Piconol (U75630) 是非甾体抗炎药物，局部使用可缓解原发性热灼伤和晒伤。
T0120	Voriconazole UK-109496,伏立康唑	Antifection; Antifungal	Microbiology/Virology
	Voriconazole (UK-109496) 是一种三唑类抗真菌剂，可抑制真菌麦角甾醇的生物合成。它特异性抑制由真菌细胞色素 P450 酶介导的 14-α-羊毛甾醇去甲基化作用
T0344	Miconazole R18134,咪康唑	Potassium Channel; NOS; Antibacterial; Antibiotic; Antifection; Antifungal	Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology
	Miconazole (R18134) 是一种具有抗菌作用的咪唑类抗真菌剂。
T6499	Fenticonazole Nitrate REC 15-1476,硝酸芬替康唑,Falvin,Lomexin	Antibiotic; Antifungal	Microbiology/Virology
	Fenticonazole Nitrate (Lomexin) 是一种抗真菌的咪唑环衍生物。它阻止麦角固醇整合和依次破坏细胞质外膜起作用。它对革兰氏阳性菌，真菌病和阴道念珠菌病有效。
T19721	Epoxiconazole BAS-480F,BAS 480F,EC 406 850 2,氟环唑,BAS480F,EC-406-850-2	Antifungal	Microbiology/Virology
	Epoxiconazole (BAS-480F) 是一种 14-α 去甲基化酶抑制剂，抑制麦角甾醇的合成和真菌细胞壁的形成。它是一种杀菌剂，对耐多菌灵和耐苯甲酰胺的菌株均表现出强大的抑制作用，可用于控制多种农作物病害。
T14179	Aliconazole	Antifungal	Microbiology/Virology
	Aliconazole 是一种具有抗真菌活性的咪唑衍生物，可用于研究皮肤感染。
T5952	Diniconazole 烯唑醇,Rac-diniconazole	Antibacterial	Microbiology/Virology
	Diniconazole (Rac-diniconazole) 是新型杀菌剂, 抑制由酵母细胞色素P-450催化的羊毛甾醇14α-脱甲基化。
T21482	Uniconazole	P450; ROS Kinase	Metabolism; Tyrosine Kinase/Adaptors
	Uniconazole 是植物生长调节剂，能够抑制细胞色素 P450 707As (Ki=68 nM)。他是分解脱落酸的酶家族成员，能够抑制赤霉素和甾醇的生物合成。
T41244	Triticonazole	Antifungal	Microbiology/Virology
	Triticonazole 是一种三唑类农药。它具有杀菌和干扰内分泌作用。
TP1559L	Ziconotide Acetate (107452-89-1 free base) 醋酸齐考诺肽,Prialt,Ziconotide Acetate	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Ziconotide Acetate (107452-89-1 free base) (Prialt) 是一种镇痛剂，已用于治疗神经性和非神经性疼痛。 Ziconotide 通过与位于伤害感受通路初级传入神经元末端部分的 N 型钙通道结合起作用，因此通过有效的镇痛作用减少突触传递。
T28777	Silicon Phthalocyanine 4 Pc-4,Pc 4,Pc4
	Silicon Phthalocyanine 4 is a drug with anti-cutaneous neoplasms activity.
T131004	3-O-Methylfunicone
	3-O-Methylfunicone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131004。
T20693	Oxiconazole Oxiconazolum,Ro13-8996,Ro 13-8996,Ro-13-8996
	Oxiconazole, an antifungal medicine, is used to treat certain kinds of yeast or fungal infections of the skin.
T73955	Potassium clavulanate mixture with silicon dioxide (1:1)
	Potassium clavulanate mixture with silicon dioxide (1:1)为Potassium clavulanate与Silicon dioxide按1:1比例混合而成的化合物。
T75710	Ziconotide TFA
	Ziconotide TFA (SNX-111 TFA)，一种肽类化合物，作为高效且选择性的N型钙通道拮抗剂，能减少突触传递，适用于慢性疼痛的研究。
T126480	(7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-xyloside
	(7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-xyloside 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126480。
T64105	Voriconazole camphorsulfonate
	Voriconazole (UK-109496) camphorsulfonate 是一种二代广谱的三唑类抗真菌 (antifungal) 化合物，对真菌麦角甾醇的生物合成表现出抑制作用。Voriconazole camphorsulfonate 能够抑制由真菌细胞色素 P450 酶介导的 14-α-羊毛甾醇去甲基化作用，表现出抗真菌效果。
T32689	Leuteonosticon
	Leuteonosticon is a peptide.
T20595	Propiconazole CGA64250,CGA-64250,CGA 64250,Desmel
	Propiconazole is an agricultural pesticide.
T31487	Dimethicone 350 Polysilane,Dimeticonum,Dimethicone,Ophtasiloxane,Dimeticona
	Dimethicone 350 is a silicone oil consisting of a mixture of fully methylated linear siloxane polymers end-blocking with trimethylsiloxy units. Commonly used in skin and hair products.
T27619	Iodiconazole
	Iodiconazole, an azole antifungal, is used potentially for the treatment of fungal infection.
T25357	Eburicone
	Eburicone 是一种羊毛甾烷型三萜类化合物，它可从香樟中分离得到，具有抗肿瘤活性。
T126440	Japonicone D
	Japonicone D 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126440。
T35335	Neticonazole SS717,Neticonazole
	Neticonazole (SS717) 是一种选择性的针对 exosome 形成和分泌的抑制剂。 Neticonazole 具有 Neticonazole 的抗真菌和抗肿瘤活性。
T62817	Fenticonazole
	Fenticonazole 是一种咪唑衍生物，具有抗菌和抗真菌作用。Fenticonazole 具有潜力进行混合性阴道炎的研究。
TP1471	Ziconotide TFA (107452-89-1 free base) Ziconotide TFA
	Ziconotide TEA acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
TP1559	Ziconotide
	Ziconotide is an atypical analgesic agent for the amelioration of severe and chronic pain. Derived from Conus magus, a cone snail, it is the synthetic form of an ω-conotoxin peptide.
T37796	Voriconazole N-oxide
	Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole . It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.
T32943	Luliconazole, (+)-
	Luliconazole, (+)- is a bioactive chemical.
T20803	Uniconazole-P S3307D,(S)-S3307,S-3307D,S 3307D,Lomica
	Uniconazole-P is an agricultural chemical.
T10027	Anticonvulsant agent 1 4-(2,2-Difluoroethenyl)-α-ethyl-2-oxo-1-pyrrolidineacetamide	Others	Others
	Anticonvulsant agent 1 is an anticonvulsant compound.
T73189	Ficonalkib
	Ficonalkib, 作为间变性淋巴瘤激酶(ALK)的有效抑制剂，其作用目标是酪氨酸激酶受体，可用于抗肿瘤药物的开发。
T125302	Versiconol
	Versiconol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125302，CAS号为 22268-13-9。

化合物

Cat.No: T27794

Synonym: lambda-Cyhalothrin,Karate,λ-氯氟氰菊酯,Icon

Target: Sodium Channel, Parasite

Cat.No: T20914

Synonym: Disflatyl,西甲硅油,Simeticone,Phazyme

Target: Others

Neticonazole Hydrochloride

Cat.No: T4985

Target: Antifungal

Cat.No: T25982

Synonym: R-126638,R126638,R 126638,Azoline

Target: Antifungal

Oxiconazole nitrate

Cat.No: T1290

Synonym: 硝酸奥昔康唑,Ro 13-8996

Target: Others, Antibiotic, Antifection, Antifungal

Cat.No: T2411

Synonym: NND 502,卢立康唑

Target: Antibiotic, Antifungal

Anticonvulsant agent 2

Cat.No: T73586

Target: Others

Ibuprofen Piconol

Cat.No: T7363

Synonym: U75630,匹美诺芬,布洛芬吡啶甲醇

Target: Others

Cat.No: T0120

Synonym: UK-109496,伏立康唑

Target: Antifection, Antifungal

Cat.No: T0344

Synonym: R18134,咪康唑

Target: Potassium Channel, NOS, Antibacterial, Antibiotic, Antifection, Antifungal

Fenticonazole Nitrate

Cat.No: T6499

Synonym: REC 15-1476,硝酸芬替康唑,Falvin,Lomexin

Target: Antibiotic, Antifungal

Cat.No: T19721

Synonym: BAS-480F,BAS 480F,EC 406 850 2,氟环唑,BAS480F,EC-406-850-2

Target: Antifungal

Cat.No: T14179

Target: Antifungal

Cat.No: T5952

Synonym: 烯唑醇,Rac-diniconazole

Target: Antibacterial

Cat.No: T21482

Target: P450, ROS Kinase

Cat.No: T41244

Target: Antifungal

Ziconotide Acetate (107452-89-1 free base)

Cat.No: TP1559L

Synonym: 醋酸齐考诺肽,Prialt,Ziconotide Acetate

Target: Calcium Channel

Silicon Phthalocyanine 4

Cat.No: T28777

Synonym: Pc-4,Pc 4,Pc4

3-O-Methylfunicone

Cat.No: T131004

Cat.No: T20693

Synonym: Oxiconazolum,Ro13-8996,Ro 13-8996,Ro-13-8996

Potassium clavulanate mixture with silicon dioxide (1:1)

Cat.No: T73955

Cat.No: T75710

(7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-xyloside

Cat.No: T126480

Voriconazole camphorsulfonate

Cat.No: T64105

Cat.No: T32689

Cat.No: T20595

Synonym: CGA64250,CGA-64250,CGA 64250,Desmel

Dimethicone 350

Cat.No: T31487

Synonym: Polysilane,Dimeticonum,Dimethicone,Ophtasiloxane,Dimeticona

Cat.No: T27619

Cat.No: T25357

Cat.No: T126440

Cat.No: T35335

Synonym: SS717,Neticonazole

Cat.No: T62817

Ziconotide TFA (107452-89-1 free base)

Cat.No: TP1471

Synonym: Ziconotide TFA

Cat.No: TP1559

Voriconazole N-oxide

Cat.No: T37796

Luliconazole, (+)-

Cat.No: T32943

Cat.No: T20803

Synonym: S3307D,(S)-S3307,S-3307D,S 3307D,Lomica

Anticonvulsant agent 1

Cat.No: T10027

Synonym: 4-(2,2-Difluoroethenyl)-α-ethyl-2-oxo-1-pyrrolidineacetamide

Target: Others

Cat.No: T73189

Cat.No: T125302

Cat. No.	Product Name	Target	Signaling Pathways
TN6770	Malabaricone A	Others	Others
	Malabaricone A 是一种生物活性化学物质。
T0344L	Miconazole nitrate NSC 169434 Nitrate,硝酸咪康唑,R18134 nitrate	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Miconazole nitrate (R18134 nitrate) 是咪唑类可抗菌的抗真菌剂。
TN6771	Malabaricone B	Others	Others
	Malabaricone B 是一种源自香料的酚类物质，它通过不依赖 p53 的途径诱导肺癌细胞中的线粒体损伤。
TN7097	Tetrahydrodehydrodiconiferyl alcohol	Others	Others
	Tetrahydrodehydrodiconiferyl alcohol 是一种天然产物。
TN3849	Dihydrodehydrodiconiferyl alcohol	TNF	Apoptosis
	Dihydrodehydrodiconiferyl alcohol 是 Liriodendron tulipifera 的甲醇提取物。
TN6772	Malabaricone C	Others	Others
	Malabaricone C 是天然的鞘磷脂合成酶抑制剂，对 SMS 1 和 SMS 2 的IC50分别为 3 和 1.5 μM。
TN4137	Glicoricone	MAO	Metabolism; Neuroscience
	Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
T3831	Licoricone	Antifection	Microbiology/Virology
	Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.
T83118	Angelicone Glabralactone
	Angelicone (Glabralactone)为香豆素类化合物，可从Fatoua villosa植物中提取。
T34642	Silicon dioxide
	Silicon dioxide is a transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid.
T32745	Liconeolignan
	Liconeolignan is extracted from the root of Glycyrrhiza uralensis.
T79975	Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside	HBV	Microbiology/Virology
	Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside（化合物1）是一种具有抗HBV活性的木脂素类化合物。该化合物对HBV表面抗原（HBsAg）的IC50为0.58 mM，而对HBV e抗原（HBeAg）的IC50 > 2.4 mM。其可从八角茴香中提取分离。
TN5432	(7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucoside
	(7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5432，CAS号为 351346-10-6。
T40611	(E)-Dehydrodiconiferyl alcohol
	(E)-Dehydrodiconiferyl alcohol is a potent dual inhibitor of hCA IX and hCA XII, effectively impeding the catalytic activity of both carbonic anhydrase isoforms. Additionally, (E)-Dehydrodiconiferyl alcohol exerts inhibitory effects on the nuclear translocation of NF-κB in the connective tissue of the healing area.
TN3802	Dehydrodiconiferyl alcohol	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Dehydrodiconiferyl alcohol （DHCA）是一种从葫芦中分离出来的木脂素，通过作为雌激素受体激动剂抑制破骨细胞分化和卵巢切除术诱导的骨质流失。
T79976	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside	HBV	Microbiology/Virology
	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside 作为一种抗HBV剂，在Hep G2.2.15细胞系上能够抑制HBsAg和HBeAg的分泌，其IC50值分别约为1.67 mM和>2.15 mM。
T82555	Dihydrodehydrodiconiferyl alcohol 9-Oglucoside
	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucopyranoside (DHD) is an extractable compound from G. mangostana L.

天然产物

Cat.No: TN6770

Target: Others

Miconazole nitrate

Cat.No: T0344L

Synonym: NSC 169434 Nitrate,硝酸咪康唑,R18134 nitrate

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: TN6771

Target: Others

Tetrahydrodehydrodiconiferyl alcohol

Cat.No: TN7097

Target: Others

Dihydrodehydrodiconiferyl alcohol

Cat.No: TN3849

Target: TNF

Cat.No: TN6772

Target: Others

Cat.No: TN4137

Target: MAO

Cat.No: T3831

Target: Antifection

Cat.No: T83118

Synonym: Glabralactone

Silicon dioxide

Cat.No: T34642

Cat.No: T32745

Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside

Cat.No: T79975

Target: HBV

(7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucoside

Cat.No: TN5432

(E)-Dehydrodiconiferyl alcohol

Cat.No: T40611

Dehydrodiconiferyl alcohol

Cat.No: TN3802

Target: Estrogen/progestogen Receptor

Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside

Cat.No: T79976

Target: HBV

Dihydrodehydrodiconiferyl alcohol 9-Oglucoside

Cat.No: T82555

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