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Search Results for " hydroxyecdysone "

2

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T4384	Halofenozide	Others	Others
	Halofenozide 是一种新的昆虫生长调节剂 (IGR)，具有苯甲酰肼结构，也是一种蜕皮激素 (ecdysteroid) 激动剂。可模拟天然昆虫蜕皮激素 20-羟基蜕皮激素的作用，
T75497	20,26-Dihydroxyecdysone
	20,26-Dihydroxyecdysone 是主要的蜕皮激素代谢物。

化合物

Cat.No: T4384

Target: Others

20,26-Dihydroxyecdysone

Cat.No: T75497

Cat. No.	Product Name	Target	Signaling Pathways
T13500	3-O-Acetyl-20-Hydroxyecdysone	Others	Others
	3-O-Acetyl-20-Hydroxyecdysone 是分离自Cyanotis arachnoidea C.B.Clark 根中的类固醇。
TN1216	2-O-Acetyl-20-hydroxyecdysone 20-Hydroxyeedysone 2-acetate	Beta Amyloid; Others	Neuroscience; Others
	2-O-Acetyl-20-hydroxyecdysone 是存在于昆虫和陆生植物中的一种蜕皮激素，2-O-Acetyl-20-hydroxyecdysone 对 amyloid-β42 诱导的细胞毒性有抑制作用，能够通过促进纤维发生减少 Aβ 寡聚物的形成，将 Aβ 寡聚物转变为低毒性纤维。
T2881	Crustecdysone Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素	Others; Caspase; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Metabolism; Others; Proteases/Proteasome
	Crustecdysone (Hydroxyecdysone) 是来源于露水草的一种蜕皮激素，可调节昆虫的蜕皮或蜕皮过程。它是 Ecdysone 的活性代谢物，通过 20E 核受体复合物 EcR-USP 抑制半胱天冬酶活性并诱导自噬，在心血管系统中具有调节或保护作用。
TN3910	Ecdysone	Apoptosis; ATPase; Glucocorticoid Receptor; Potassium Channel; Sodium Channel; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism
	Ecdysone 是存在于昆虫和草药中的主要类固醇激素，可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。
TN3911	Ecdysterone 2,3:20,22-diacetonide	Others	Others
	Due to the multi-drug resistance reversal activity of the less polar ecdysteroids, several new products( including 20-hydroxyecdysone,20-hydroxyecdysone 2,3;20,22-diacetonide) are promising for being tested against various cancer cell lines.
TN2287	Turkesterone	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistress activity, can increase the adaptation capacity of mice under immobilization-induced stress conditions.

天然产物

3-O-Acetyl-20-Hydroxyecdysone

Cat.No: T13500

Target: Others

2-O-Acetyl-20-hydroxyecdysone

Cat.No: TN1216

Synonym: 20-Hydroxyeedysone 2-acetate

Target: Beta Amyloid, Others

Cat.No: T2881

Synonym: Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素

Target: Others, Caspase, Endogenous Metabolite, Autophagy

Cat.No: TN3910

Target: Apoptosis, ATPase, Glucocorticoid Receptor, Potassium Channel, Sodium Channel, Endogenous Metabolite, Autophagy

Ecdysterone 2,3:20,22-diacetonide

Cat.No: TN3911

Target: Others

Cat.No: TN2287

Target: Calcium Channel

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