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Search Results for " genistein "

7

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T69260	Genistein Diglucuronide
	Genistein Diglucuronide is a metabolite of Genistein which exhibits specific inhibitory activity against tyrosine kinases including autophosphorylation of epidermal growth factor receptor kinase.
T69863	Dihydrogenistein
	Dihydrogenistein is a derivative of Genistein -- a compound that exhibits specific inhibitory activity against tyrosine kinases including autophosphorylation of epidermal growth factor receptor kinase.
T71960	Aminogenistein
	Aminogenistein inhibits protein-tyrosine kinase activity of p56lck.
T126492	3',5'-Diprenylgenistein
	3',5'-Diprenylgenistein 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126492。
T36350	Cho-Arg (trifluoroacetate salt)
	Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the cav...
T36368	2H-Cho-Arg (trifluoroacetate salt)
	2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and t...
T36359	Dios-Arg (trifluoroacetate salt)
	Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4. Dios-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence and absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the cav...

化合物

Genistein Diglucuronide

Cat.No: T69260

Dihydrogenistein

Cat.No: T69863

Cat.No: T71960

3',5'-Diprenylgenistein

Cat.No: T126492

Cho-Arg (trifluoroacetate salt)

Cat.No: T36350

2H-Cho-Arg (trifluoroacetate salt)

Cat.No: T36368

Dios-Arg (trifluoroacetate salt)

Cat.No: T36359

Cat. No.	Product Name	Target	Signaling Pathways
T1737	Genistein NPI 031L,三叶草,染料木素,金雀异黄酮	Apoptosis; EGFR; Endogenous Metabolite; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
	Genistein (NPI 031L) 是一种大豆异黄酮，是一种多重的酪氨酸激酶抑制剂，通过改变细胞凋亡，细胞周期和血管生成以及抑制转移对多种癌症有化疗作用。
T13701	Genistein 8-c-glucoside G8CG	Mitochondrial Metabolism	Metabolism
	Genistein 8-c-glucoside (G8CG) 诱导线粒体膜去极化从而导致细胞凋亡。Genistein 8-c-glucoside 是一种来源于 Lupinus luteus L.花中的天然葡萄糖苷。
T3233	Sophoricoside Genistein sophoricoside,槐苷	Others	Others
	Sophoricoside (Genistein sophoricoside) 是一种异黄酮糖苷，从槐花中分离得到，具有抗炎，抗癌和免疫抑制作活性。
T2882	Genistin 染料木甙,Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside,染料木苷	Apoptosis; Estrogen Receptor/ERR; Others	Apoptosis; Endocrinology/Hormones; Others
	Genistin (Genistoside) 是一种植物雌激素家族的异黄酮，是一种抗脂肪生成剂。它通过调节ERalpha 信号通路抑制乳腺癌细胞生长和促进凋亡细胞死亡。
TN4125	Genistein 7-O-glucuronide	Others	Others
	Genistein 7-O-glucuronide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4125，CAS号为 38482-81-4。
TN1679	Genistein 7,4'-di-O-β-D-glucoside 染料木素-7,4'-二-O-Β-D-葡萄糖苷,Genistein 7,4'-di-O-beta-D-glucopyranoside,鲁冰花	Others; Estrogen/progestogen Receptor	Endocrinology/Hormones; Others
	Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range.
TN6335	8-(1,1-Dimethylallyl)genistein 5,7,4'-Trihydroxy-8-(1,1-dimethylprop-2-enyl)isoflavone
	8-(1,1-Dimethylallyl)genistein 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6335，CAS号为 651750-08-2。
TN1680	Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] Genistein 7-O-beta-D-glucopyranoside-4'-O-[alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside],染料木素-7-O-Β-D-葡萄糖苷-4'-O-[Α-L-鼠李糖基-(1-2)-Β-D-葡萄糖苷]	Others	Others
	Genistein 7-O-beta-D-glucopyranoside-4'-O-[alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside] is a natural product
T13922	Thevetiaflavone 2-Genistein-5-methyl ether,Apigenin-5-methyl ether	BCL; Caspase	Apoptosis; Proteases/Proteasome
	Thevetiaflavone (2-Genistein-5-methyl ether) 是一种来自 Wikstroemia indica 的天然类黄酮，可抑制乳酸脱氢酶从细胞质中泄漏并提高细胞活力。
TN2767	2'-Hydroxygenistein 鲁冰花	Antifection	Microbiology/Virology
	2'-Hydroxygenistein has antifungal activity, dimerization of it causes a remarkable increase of antifungal activity. It shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B. 2'-Hydroxygenistein of genistein can enhance its antioxidant activity and cell cytotoxicity in MCF-7 human breast cancer cells.
TN1301	6,8-Diprenylgenistein 6,8-二异戊烯基金雀异黄素,鲁冰花	Antifection	Microbiology/Virology
	6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria.
TN3179	6-Methylgenistein	Others	Others
	6-Methylgenistein is a natural product from Sophora dunnii.
TN3133	5-O-Methylgenistein	Others	Others
	5-O-Methylgenistein may show free radical scavenging activity, it also may have hepatoprotective property on the model of toxic hepatitis induced by carbon tetrachloride damage.
T1238	Daidzein 大豆素,Isoflavone,黄豆苷元	Endogenous Metabolite; PPAR	DNA Damage/DNA Repair; Metabolism
	Daidzein (Isoflavone) 是一种来自大豆的异黄酮提取物，是酪氨酸激酶抑制剂染料木黄酮的无活性类似物，具有抗氧化和植物雌激素特性。
T4000	(±)-Equol Equol,(±)-雌马酚,(R,S)-Equol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	(±)-Equol ((R,S)-Equol) 是 equol 的外消旋体。它对 ERα 和 ERβ 的 EC50s of 分别为 200 和 74 nM。Equol 是大豆异黄酮黄豆苷和大豆黄素的代谢产物。

天然产物

Cat.No: T1737

Synonym: NPI 031L,三叶草,染料木素,金雀异黄酮

Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy

Genistein 8-c-glucoside

Cat.No: T13701

Synonym: G8CG

Target: Mitochondrial Metabolism

Cat.No: T3233

Synonym: Genistein sophoricoside,槐苷

Target: Others

Cat.No: T2882

Synonym: 染料木甙,Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside,染料木苷

Target: Apoptosis, Estrogen Receptor/ERR, Others

Genistein 7-O-glucuronide

Cat.No: TN4125

Target: Others

Genistein 7,4'-di-O-β-D-glucoside

Cat.No: TN1679

Synonym: 染料木素-7,4'-二-O-Β-D-葡萄糖苷,Genistein 7,4'-di-O-beta-D-glucopyranoside,鲁冰花

Target: Others, Estrogen/progestogen Receptor

8-(1,1-Dimethylallyl)genistein

Cat.No: TN6335

Synonym: 5,7,4'-Trihydroxy-8-(1,1-dimethylprop-2-enyl)isoflavone

Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside]

Cat.No: TN1680

Synonym: Genistein 7-O-beta-D-glucopyranoside-4'-O-[alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside],染料木素-7-O-Β-D-葡萄糖苷-4'-O-[Α-L-鼠李糖基-(1-2)-Β-D-葡萄糖苷]

Target: Others

Thevetiaflavone

Cat.No: T13922

Synonym: 2-Genistein-5-methyl ether,Apigenin-5-methyl ether

Target: BCL, Caspase

2'-Hydroxygenistein

Cat.No: TN2767

Synonym: 鲁冰花

Target: Antifection

6,8-Diprenylgenistein

Cat.No: TN1301

Synonym: 6,8-二异戊烯基金雀异黄素,鲁冰花

Target: Antifection

6-Methylgenistein

Cat.No: TN3179

Target: Others

5-O-Methylgenistein

Cat.No: TN3133

Target: Others

Cat.No: T1238

Synonym: 大豆素,Isoflavone,黄豆苷元

Target: Endogenous Metabolite, PPAR

Cat.No: T4000

Synonym: Equol,(±)-雌马酚,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

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