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Search Results for " gdf15 "

Targets Recommended: AMPK

2

抑制剂 & 化合物

21

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T78791	AMPK activator 12	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	AMPK activator 12 是一种 AMPK 激活剂和 GDF15 诱导剂，能提升人肝细胞内GDF15蛋白的表达水平，可用于研究癌症。
T76774	Ponsegromab PF 06946860	TGF-beta/Smad	Stem Cells
	Ponsegromab (PF 06946860) 是一种具有选择性和有效性的人源化抗 GDF15 抗体抑制剂。 Ponsegromab 具有抗恶病质活性，通过与 GDF15 结合来阻止其与 GFRAL 结合，从而中断 GDF15/GFRAL 介导的信号传导。 Ponsegromab 具有潜在的抗癌活性，可用于治疗患有癌症厌食-恶病质综合征的癌症患者。

化合物

AMPK activator 12

Cat.No: T78791

Target: AMPK

Cat.No: T76774

Synonym: PF 06946860

Target: TGF-beta/Smad

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01246	GDF-15 Protein, Mouse, Recombinant (His) MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-...	Mouse	E. coli
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec...
TMPK-01243	GDF-15 Protein, Rat, Recombinant (His) GDF-15,PDF,PTGF-beta,MIC-1,MIC1,GDF	Rat	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.
TMPK-01244	GDF-15 Protein, Mouse, Recombinant (hFc) PTGFBPTGF-beta,PTGFB,PLAB,NAG-1,Placental TGF-β,RG-1,GDF...	Mouse	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec...
TMPK-00569	GDF-15 Protein, Canine, Recombinant (His) GDF15,MIC1,MIC-1,PLAB,GDF-15<...	Canine	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.12 kDa and the accession number is A0A8C0TNP6.
TMPK-00196	GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated NAG-1,Placental TGF-beta,PTGFBPTGF-β,PDF,Placental TGF-β,PTG...	Human	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession nu...
TMPK-00665	GDF-15 Protein, Cynomolgus, Recombinant (His) PTGFBPTGF-beta,PTGFBPTGF-β,MIC-1,NAG-1,MIC1,PTGF-beta,PTGF-β...	Cynomolgus	E. coli
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus...
TMPK-00663	GDF-15 Protein, Cynomolgus, Recombinant (hFc) PTGF-β,GDF-15,NAG-1,PTGF-beta,PDF,PTGFBPTG...	Cynomolgus	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus...
TMPK-00197	GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated Placental TGF-β,GDF15,RG-1,MIC-1,PTGFB,PTG...	Human	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-01245	GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated RG-1,GDF15,Placental TGF-beta,GDF...	Mouse	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00198	GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF	Human	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00664	GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated Placental TGF-beta,PTGFBPTGF-β,PLAB,MIC-1,GDF15...	Cynomolgus	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPY-04727	GDF-15 Protein, Human, Recombinant (His) PLAB,PTGFB,NAG-1,MIC1,GDF-15,PDF,MIC-1,gro...	Human	P. pastoris (Yeast)
	GDF-15 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 13.7 kDa and the accession number is Q99988.
TMPY-01073	GDF-15 Protein, Human, Recombinant (hFc) PTGFB,PLAB,MIC-1,MIC1,PDF,NAG-1,growth differentiation facto...	Human	HEK293 Cells
	GDF-15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.6 kDa and the accession number is Q99988.
TMPJ-01414	GDF-15 Protein, Mouse, Recombinant (His & Flag) Growth Differentiation Factor 15, Macrophage inhibi...	Mouse	HEK293 Cells
	Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be secreted by a wide variety of cell types in response to a broad range of stressors. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenito...
TMPK-01059	GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated GFRAL/GFR α-like Protein,C6orf144,GFRAL,GFR alpha-like,GFR α...	Human	HEK293 Cells
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Human, Recombinant (...
TMPK-01058	GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi) GFR alpha-like,GFRAL,C6orf144,GRAL,GFR α-like,GFRAL/GFR α-li...	Human	HEK293 Cells
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Human, Recombinant (...
TMPK-01060	GFRAL/GFR alpha-like Protein, Human, Recombinant (hFc) GFRAL,GRAL,C6orf144,GFR alpha-like,GFR α-like,GFRAL/GFR α-li...	Human	HEK293 Cells
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Human, Recombinant (...
TMPK-01319	GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi) GFR alpha like,GRAL,GFRAL,C6orf144,GFRAL/GFR α-like Protein,...	Cynomolgus	HEK293 Cells
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombin...
TMPK-01053	GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated GRAL,GFRAL/GFR α-like Protein,GFR alpha-like,GFR α-like,GFRA...	Mouse	HEK293 Cells
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (...
TMPK-01052	GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi) GFRAL/GFR α-like Protein,GFR α-like,GRAL,C6orf144,GFR alpha-...	Mouse	HEK293 Cells
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (...
TMPK-01320	GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated GRAL,GFRAL,C6orf144,GFRAL/GFR α-like Protein,GFR α-like,GFR ...	Cynomolgus	HEK293 Cells
	GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombin...

重组蛋白

GDF-15 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01246

Species: Mouse

Expression System: E. coli

GDF-15 Protein, Rat, Recombinant (His)

Cat.No: TMPK-01243

Species: Rat

Expression System: E. coli

GDF-15 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-01244

Species: Mouse

Expression System: HEK293 Cells

GDF-15 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00569

Species: Canine

Expression System: E. coli

GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00196

Species: Human

Expression System: E. coli

GDF-15 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00665

Species: Cynomolgus

Expression System: E. coli

GDF-15 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPK-00663

Species: Cynomolgus

Expression System: HEK293 Cells

GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated

Cat.No: TMPK-00197

Species: Human

Expression System: HEK293 Cells

GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated

Cat.No: TMPK-01245

Species: Mouse

Expression System: HEK293 Cells

GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00198

Species: Human

Expression System: HEK293 Cells

GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00664

Species: Cynomolgus

Expression System: HEK293 Cells

GDF-15 Protein, Human, Recombinant (His)

Cat.No: TMPY-04727

Species: Human

Expression System: P. pastoris (Yeast)

GDF-15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01073

Species: Human

Expression System: HEK293 Cells

GDF-15 Protein, Mouse, Recombinant (His & Flag)

Cat.No: TMPJ-01414

Species: Mouse

Expression System: HEK293 Cells

GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01059

Species: Human

Expression System: HEK293 Cells

GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01058

Species: Human

Expression System: HEK293 Cells

GFRAL/GFR alpha-like Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01060

Species: Human

Expression System: HEK293 Cells

GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi)

Cat.No: TMPK-01319

Species: Cynomolgus

Expression System: HEK293 Cells

GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01053

Species: Mouse

Expression System: HEK293 Cells

GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-01052

Species: Mouse

Expression System: HEK293 Cells

GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01320

Species: Cynomolgus

Expression System: HEK293 Cells

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