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Cat. No. | Product Name | ||
---|---|---|---|
L2520 | 糖代谢化合物库 | 702 compounds | |
702 种糖代谢相关的化合物,可用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11347 |
G6PD activator AG1
|
Others | Others |
G6PD activator AG1 is a glucose-6-phosphate dehydrogenase (G6PD) activator with an EC50 of 3 µΜ. | |||
T8640 |
G6PDi-1
|
Dehydrogenase | Metabolism |
G6PDi-1 是一种有效的 G6PD 抑制剂。它消耗 NADPH 并减少炎性细胞因子的产生。 | |||
T7400 |
RRX-001
|
Apoptosis; Dehydrogenase; Parasite | Apoptosis; Metabolism; Microbiology/Virology |
RRx-001 是一种低氧选择性的表观遗传因子,被用作放射或化疗敏感剂,能诱发凋亡,克服骨髓瘤的耐药性。它是G6PD 的有效抑制剂,具有抗疟、抗癌活性。它是免疫检查点的抑制剂,可下调CD47和SIRP-α。 | |||
T69426 | CB-83 | ||
CB-83 is a novel G6PD inhibitor. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3427 |
Polydatin
Piceid,虎杖苷,Polydotin Peceid |
Apoptosis; Mitophagy; NF-κB; Autophagy | Apoptosis; Autophagy; NF-κB |
Polydatin (Piceid) 是从传统中药虎杖根中提取的一种天然产物,在多个实验模型中具有抗炎作用。它可抑制 G6PD,并诱导氧化和内质网应激。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00836 |
G6PD Protein, Human, Recombinant (His)
Glucose-6-Phosphate 1-Dehydrogenase,G6PD |
Human | HEK293 Cells |
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the re... |